Quantitative Analysis of the Influenza Virus-Specific CD4+ T Cell Memory in the Absence of B Cells and Ig

Journal of Immunology

Volumn 157, Issue 7, 1996, Pages 2947-2952

  Topham, David J ^a   Tripp, Ralph A ^a   Hamilton Easton, Ann Marie ^a   Sarawar, Sally R ^a   Doherty, Peter C ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M; IMMUNOGLOBULIN MU CHAIN; INTERLEUKIN 2; VIRUS ANTIBODY;

AGAMMAGLOBULINEMIA; ANIMAL; ARTICLE; B LYMPHOCYTE; C57BL MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CROSS BREEDING; DENDRITIC CELL; FEMALE; GENETICS; GERMINAL CENTER; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; IMMUNOPHENOTYPING; INFLUENZA VIRUS A; LYMPH NODE; LYMPHOCYTE COUNT; MALE; MOUSE; MOUSE MUTANT; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; SECRETION; SPLEEN;

AGAMMAGLOBULINEMIA; ANIMALS; ANTIBODIES, VIRAL; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CROSSES, GENETIC; DENDRITIC CELLS; FEMALE; GERMINAL CENTER; IMMUNOGLOBULIN M; IMMUNOGLOBULIN MU-CHAINS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INFLUENZA A VIRUS; INTERLEUKIN-2; LYMPH NODES; LYMPHOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORTHOMYXOVIRIDAE INFECTIONS; SPLEEN;

EID: 0030265542     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Scherle, P. A., and W. Gerhard. 1986. Functional analysis of influenza-specific helper T cell clones in vivo: T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. J. Exp. Med. 164:1114.
2. Eichelberger, M. C., M. Wang, W. Allan, R. G. Webster, and P. C. Doherty. 1991. Influenza virus RNA in the lung and lymphoid tissue of immunologically intact and CD4-depleted mice. J. Gen. Virol. 72:1695.
3. Hayglass, K. T., S. J. Naides, C . F. Scott, Jr., B. Benacerraf, and M.-S. Sy. 1986. T Cell development in B cell-deficient mice. J. Immunol. 136:823.
4. Janeway, C. A., Jr., J. Ron, and M. E. Katz. 1987. The B cell is the initiating antigen-presenting cell in peripheral lymph nodes. J. Immunol. 138:1051.
5. Fuchs, E. J., and P. Matzinger. 1992. B cells turn off virgin but not memory T cells. Science 258:1156.
6. + T cells: ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response. J. Immunol. 155:45.
7. Liu, Y., L. Ramarathinam, A. Guo, D. Huszar, M. Trounstine, and M. Zhao. 1995. Gene-targeted B-deficient mice reveal a critical role for B cells in the CD4 response. Int. Immunol. 7:1353.
8. Kitamura, D., and K. Rajewsky. 1992. Targeted disruption of μchain membrane exon causes loss of heavy- chain allelic exclusion. Nature 356:154.
9. + T cells. J. Immunol. 154:4915.
10. Epstein, M. M., F. Di Rosa, D. Jankovic, A. Sher, and P. Matzinger. 1995. Successful T cell priming in B cell-deficient mice. J. Exp. Med. 182:915.
11. + T cells. Virology 210:179.
12. Gray, D. 1993. Immunological memory. Annu. Rev. Immunol. 11:49.
13. Kitamura, D., J. Roes, R. Kuhn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350:423.
14. + T cells. J. Immunol. 144:3980.
15. + memory T cells. J. Immunol. 154:5870.
16. + T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype. J. Immunol. 150:5494.
17. Sarawar, S. R., and P. C. Doherty. 1994. Concurrent production of interleukin-2, interleukin-10 and γ-interferon in the regional lymph nodes of mice with influenza pneumonia. J. Virol. 68:3112.
18. Picker, L. J. 1994. Control of lymphocyte homing. Curr. Opin. Immunol. 6:394.
19. Hou, S., L. Hyland, L. M. Bradley, S. R. Watson, and P. C. Doherty. 1995. Subverting lymph node trafficking by treatment with the Mel-14 monoclonal antibody to L-selectin does not prevent an effective host response to Sendai virus. J. Immunol. 155:252.
20. Bodmer, H., G. Obert, S. Chan, C. Benoist, and D. Mathis. 1993. Environmental modulation of the autonomy of cytotoxic T lymphocytes. Eur. J. Immunol. 23: 1649.
21. b gene. J. Immunol. 155:2955.
22. Cardell, S., M. Merkenschlager, H. Bodmer, S. Chan, D. Cosgrove, C. Benoist, and D. Mathis. 1994. The immune system of mice lacking conventional MHC class II molecules. Adv. Immunol. 55:423.
23. Hou, S., X. Y. Mo, L. Hyland, and P. C. Doherty. 1995. Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins. J. Virol. 69:1429.
24. Yap, K. L., and G. L. Ada. 1978. The recovery of mice from influenza A virus infection: adoptive transfer of immunity with influenza virus-specific cytotoxic T lymphocytes recognizing a common virion antigen. Scand. J. Immunol. 8:413.
25. Lin, Y. L., and B. A. Askonas. 1981. Biological properties of an influenza A virus-specific killer T cell clone: inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions. J. Exp. Med. 154:225.
26. Michels, J. E., T. F. Fitzgeral, and N. J. Roberts, Jr. 1993. Human macrophage responses to vaccine strains of influenza virus: synthesis of viral proteins, interleukin-1β, interleukin-6, tumour necrosis factor-α and interleukin-1 inhibitor. Vaccine 11:36.
27. Hamilton-Easton, A. M., and M. Eichelberger. 1995. Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice. J. Virol. 69:6359.
28. Walker, J. A., T. Sakaguchi, Y. Matsuda, T. Yoshida, and Y. Kawaoka. 1992. Location and character of the cellular enzyme that cleaves the hemagglutinin of a virulent avian influenza virus. Virology 190:278.
29. Schon-Hegrad, M. A., J. Oliver, P. G. McMenamin, and P. G. Holt. 1991. Studies on the density, distribution, and surface phenotype of intra epithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J. Exp. Med. 173:1345.
30. Malnati, M. S., S. Ceman, M. Weston, R. DeMars, and E. O. Long. 1993. Presentation of cytosolic antigen by HLA-DR requires a function encoded in the class II region of the MHC. J. Immunol. 151:6751.
31. Pinet, V., M. S. Malnati, and E. O. Long. 1994. Two processing pathways for the MHC class II-restricted presentation of exogenous influenza virus antigen. J. Immunol. 152:4852.
32. Bradley, L. M., M. Croft, and S. L. Swain. 1993. T-cell memory: new perspectives. Immunol. Today 14:197.
33. Bradley, L. M., S. R. Watson, and S. L. Swain. 1994. Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin. J. Exp. Med. 180:2401.
34. Kapasi, Z. F., G. F. Burton, L. D. Shultz, J. G. Tew, and A. K. Szakal. 1993. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. J. Immunol. 150:2648.