Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers

European Journal of Pharmaceutical Sciences

Volumn 46, Issue 5, 2012, Pages 446-454

  Xia, Dengning ^a,b   Wu, Jian X ^b   Cui, Fude ^a   Qu, Haiyan ^c   Rades, Thomas ^b,d   Rantanen, Jukka ^b   Yang, Mingshi ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Amorphous; Crystalline; Image analysis; Nitrendipine; Solid state transformation

Indexed keywords

CRYSTALLIN; MACROGOL; NITRENDIPINE; POLYMER; POLYVINYL ALCOHOL; SOLVENT;

AMORPHOUS PARTICLE SUSPENSION; ARTICLE; CRYSTALLIZATION; GROWTH RATE; IMAGE ANALYSIS; MICROSCOPY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SUSPENSION; X RAY DIFFRACTION;

CALCIUM CHANNEL BLOCKERS; CHEMICAL PRECIPITATION; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; KINETICS; MICROSCOPY, POLARIZATION; MOLECULAR STRUCTURE; NITRENDIPINE; PHASE TRANSITION; POLYETHYLENE GLYCOLS; POLYVINYL ALCOHOL; POWDER DIFFRACTION; SOLVENTS; SPECTRUM ANALYSIS, RAMAN; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 84861188276     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.03.008     Document Type: Article

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