Inhibition of the p38 and PKA signaling pathways is associated with the anti-melanogenic activity of Qian-wang-hong-bai-san, a Chinese herbal formula, in B16 cells

Journal of Ethnopharmacology

Volumn 141, Issue 2, 2012, Pages 622-628

  Tsang, Ting Fung ^a   Ye, Yan ^a   Tai, William Chi Shing ^a   Chou, Gui Xin ^b   Leung, Alexander Kai Man ^a   Yu, Zhi Ling ^a   Hsiao, Wen Luan Wendy ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b Shanghai R and D Center for Standardization of Chinese Medicines   (China)

Author keywords

B16 cells; Melanogenesis; p38 MAPK; PKA; Qian wang hong bai san; Traditional Chinese medicine; Tyrosinase

Indexed keywords

CHINESE DRUG; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DERMATOLOGICAL AGENT; MELANIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOPHENOL MONOOXYGENASE; QIAN WANG HONG BAI SAN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPECTROPHOTOMETER; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLEACHING AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; INTRAMOLECULAR OXIDOREDUCTASES; MEDICINE, CHINESE TRADITIONAL; MELANINS; MELANOMA, EXPERIMENTAL; MICE; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLANTS, MEDICINAL; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SKIN PIGMENTATION; SPECTROPHOTOMETRY; TIME FACTORS;

EID: 84861184204     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.08.043     Document Type: Article

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