Immediate ozone effects on heart rate and repolarisation parameters in potentially susceptible individuals

Occupational and Environmental Medicine

Volumn 69, Issue 6, 2012, Pages 428-436

  Hampel, Regina ^a   Breitner, Susanne ^a,b   Zareba, Wojciech ^c   Kraus, Ute ^a,b   Pitz, Mike ^a,d   Geruschkat, Uta ^a   Belcredi, Petra ^a,e   Peters, Annette ^a   Schneider, Alexandra ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d UNIVERSITY OF AUGSBURG   (Germany)

^e UNIVERSITY HOSPITAL AUGSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

OZONE;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; ELECTROCARDIOGRAM; ELECTROCARDIOGRAPHY; FEMALE; GENETIC PREDISPOSITION; HEART INFARCTION; HEART RATE; HEART REPOLARIZATION; HUMAN; HYPERTENSION; IMPAIRED GLUCOSE TOLERANCE; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OZONE DEPLETION; PRIORITY JOURNAL; QT INTERVAL; SUMMER; T WAVE AMPLITUDE; WINTER;

AGED; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; ELECTROCARDIOGRAPHY; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERMANY; GLUCOSE INTOLERANCE; HEART RATE; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; MYOCARDIAL CONTRACTION; OXIDANTS, PHOTOCHEMICAL; OZONE; PROSPECTIVE STUDIES;

EID: 84861183202     PISSN: 13510711     EISSN: 14707926     Source Type: Journal    
DOI: 10.1136/oemed-2011-100179     Document Type: Article

References (45)

1. Ruidavets JB, Cournot M, Cassadou S, et al. Ozone air pollution is associated with acute myocardial infarction. Circulation 2005;111:563-9.
2. Henrotin JB, Zeller M, Lorgis L, et al. Evidence of the role of short-term exposure to ozone on ischaemic cerebral and cardiac events: the Dijon Vascular Project (DIVA). Heart 2010;96:1990-6.
3. Medina-Ramon M, Zanobetti A, Schwartz J. The effect of ozone and PM10 on hospital admissions for pneumonia and chronic obstructive pulmonary disease: A national multicity study. Am J Epidemiol 2006;163:579-88.
4. Gryparis A, Forsberg B, Katsouyanni K, et al. Acute effects of ozone on mortality from the "Air pollution and health: A European approach" project. Am J Respir Crit Care Med 2004;170:1080-7. (Pubitemid 39488620)
5. Bell ML, Dominici F, Samet JM. A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution study. Epidemiology 2005;16:436-45. (Pubitemid 40847827)
6. Stafoggia M, Forastiere F, Faustini A, et al. Susceptibility factors to ozone-related mortality a population-based case-crossover analysis. Am J Respir Crit Care Med 2010;182:376-84.
7. Chuang KJ, Chan CC, Su TC, et al. The effect of urban air pollution on inflammation, oxidative stress, coagulation, and autonomic dysfunction in young adults. Am J Respir Crit Care Med 2007;176:370-6.
8. Zanobetti A, Gold DR, Stone PH, et al. Reduction in heart rate variability with traffic and air pollution in patients with coronary artery disease. Environ Health Perspect 2010;118:324-30.
9. Hampel R, Schneider A, Bruske I, et al. Altered Cardiac Repolarization in Association with Air Pollution and Air Temperature among Myocardial Infarction Survivors. Environ Health Perspect 2010;118:1755-61.
10. Schneider A, Neas LM, Graff DW, et al. Association of cardiac and vascular changes with ambient PM2.5 in diabetic individuals. Part Fibre Toxicol 2010;7:14.
11. Henneberger A, Zareba W, Ibald-Mulli A, et al. Repolarization changes induced by air pollution in ischemic heart disease patients. Environ Health Perspect 2005;113:440-6. (Pubitemid 40612995)
12. Liao D, Shaffer ML, Rodriguez-Colon S, et al. Acute adverse effects of fine particulate air pollution on ventricular repolarization. Environ Health Perspect 2010;118:1010-15.
13. Baja ES, Schwartz JD, Wellenius GA, et al. Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the normative aging study. Environ Health Perspect 2010;118:840-6.
14. Zanobetti A, Stone PH, Speizer FE, et al. T-wave alternans, air pollution and traffic in high-risk subjects. Am J Cardiol 2009;104:665-70.
15. Roden DM. Keep the QT interval: it is a reliable predictor of ventricular arrhythmias. Heart Rhythm 2008;5:1213-15.
16. Greenland P, Xie X, Liu K, et al. Impact of minor electrocardiographic ST-segment and/or T-wave abnormalities on cardiovascular mortality during long-term follow-up. Am J Cardiol 2003;91:1068-74. (Pubitemid 36514921)
17. Medina-Ramon M, Schwartz J. Who is more vulnerable to die from ozone air pollution? Epidemiology 2008;19:672-9.
18. Srebot V, Gianicolo EA, Rainaldi G, et al. Ozone and cardiovascular injury. Cardiovasc Ultrasound 2009;7:30.
19. Hayes JD, Strange RC. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 2000;61:154-66.
20. Franklin M, Schwartz J. The impact of secondary particles on the association between ambient ozone and mortality. Environ Health Perspect 2008;116:453-8. (Pubitemid 351864302)
21. Sivagangabalan G, Spears D, Masse S, et al. The effect of air pollution on spatial dispersion of myocardial repolarization in healthy human volunteers. J Am Coll Cardiol 2011;57:198-206.
22. Wichmann HE, Gieger C, Illig T. KORA-generesource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 2005;67 (Suppl 1):S26-30.
23. Holle R, Happich M, Lowel H, et al. KORAea research platform for population based health research. Gesundheitswesen 2005;67(Suppl 1):S19-25.
24. Cyrys J, Pitz M, Heinrich J, et al. Spatial and temporal variation of particle number concentration in Augsburg, Germany Sci Total Environ 2008;401:168-75.
25. Pitz M, Schmid O, Heinrich J, et al. Seasonal and diurnal variation of PM2.5 apparent particle density in urban air in Augsburg, Germany Environ Sci Technol 2008;42:5087-93.
26. Rich DQ, Mittleman MA, Link MS, et al. Increased risk of paroxysmal atrial fibrillation episodes associated with acute increases in ambient air pollution. Environ Health Perspect 2006;114:120-3.
27. Luttmann-Gibson H, Suh HH, Coull BA, et al. Systemic inflammation, heart rate variability and air pollution in a cohort of senior adults. Occup Environ Med 2010;67:625-30.
28. Brook RD, Rajagopalan S, Pope CA III, et al. Particulate Matter Air Pollution and Cardiovascular Disease. An Update to the Scientific Statement From the American Heart Association. Circulation 2010;121:2331-78.
29. Gold DR, Litonjua A, Schwartz J, et al. Ambient pollution and heart rate variability. Circulation 2000;101:1267-73. (Pubitemid 30158614)
30. Chen JC, Cavallari JM, Stone PH, et al. Obesity is a modifier of autonomic cardiac responses to fine metal particulates. Environ Health Perspect 2007;115:1002-6. (Pubitemid 47317062)
31. Adar SD, Gold DR, Coull BA, et al. Focused exposures to airborne traffic particles and heart rate variability in the elderly. Epidemiology 2007;18:95-103. (Pubitemid 46005914)
32. Luttmann-Gibson H, Suh HH, Coull BA, et al. Short-term effects of air pollution on heart rate variability in senior adults in Steubenville, Ohio. J Occup Environ Med 2006;48:780-8. (Pubitemid 44221832)
33. Peters A, Perz S, Doring A, et al. Increases in heart rate during an air pollution episode. Am J Epidemiol 1999;150:1094-8. (Pubitemid 29531946)
34. Pope CAI, Verrier RL, Lovett EG, et al. Heart rate variability associated with particulate air pollution. Am Heart J 1999;138:890-9. (Pubitemid 29523276)
35. Stein PK, Sanghavi D, Sotoodehnia N, et al. Association of Holter-based measures including T-wave alternans with risk of sudden cardiac death in the community-dwelling elderly: the Cardiovascular Health Study. J Electrocardiol 2010;43:251-9.
36. Lin KB, Shofer FS, McCusker C, et al. Predictive value of T-wave abnormalities at the time of emergency department presentation in patients with potential acute coronary syndromes. Acad Emerg Med 2008;15:537-43.
37. Beckman JA, Creager MA, Libby P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 2002;287:2570-81. (Pubitemid 34517204)
38. Perciaccante A, Fiorentini A, Paris A, et al. Circadian rhythm of the autonomic nervous system in insulin resistant subjects with normoglycemia, impaired fasting glycemia, impaired glucose tolerance, type 2 diabetes mellitus. BMC Cardiovasc Disord 2006;6:19.
39. Chahine T, Baccarelli A, Litonjua A, et al. Particulate air pollution, oxidative stress genes, and heart rate variability in an elderly cohort. Environ Health Perspect 2007;115:1617-22.
40. Mordukhovich I, Wilker E, Suh H, et al. Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study. Environ Health Perspect 2009;117:1767-72.
41. Schwartz J, Park SK, O'Neill MS, et al. Glutathione-S-transferase M1, obesity, statins, and autonomic effects of particles: gene-by-drug-by- environment interaction. Am J Respir Crit Care Med 2005;172:1529-33. (Pubitemid 43076541)
42. Romieu I, Ramirez-Aguilar M, Sienra-Monge JJ, et al. GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone. Eur Respir J 2006;28:953-9. (Pubitemid 46331964)
43. Reisenauer CS, Koenig JQ, McManus MS, et al. Pulmonary response to ozone exposures in healthy individuals aged 55 years or greater. JAPCA 1988;38:51-5. (Pubitemid 18040058)
44. Ren C, Melly S, Schwartz J. Modifiers of short-term effects of ozone on mortality in eastern Massachusetts - a case-crossover analysis at individual level. Environ Health 2010;9:3.
45. Lee K, Parkhurst WJ, Xue JP, et al. Outdoor/indoor/personal ozone exposures of children in Nashville, Tennessee. Air Waste Manag Assoc 2004;54:352-9. (Pubitemid 38296108)