Impaired renal function is associated with greater urinary strong ion differences in critically ill patients with metabolic acidosis

Journal of Critical Care

Volumn 27, Issue 3, 2012, Pages 255-260

  Moviat, Miriam ^a   Terpstra, Anniek M ^b   van der Hoeven, Johannes G ^b   Pickkers, Peter ^b  

^a JEROEN BOSCH HOSPITAL   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Chloride; Critically ill; Metabolic acidosis; Renal failure; Stewart

Indexed keywords

CHLORIDE ION; SODIUM ION;

ADOLESCENT; ADULT; AGED; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; DISEASE ASSOCIATION; FEMALE; HUMAN; KIDNEY DYSFUNCTION; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; PH; STATISTICAL ANALYSIS; URINALYSIS; URINARY EXCRETION;

ACIDOSIS; ACUTE KIDNEY INJURY; AGED; CHLORIDES; CREATININE; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LINEAR MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROSPECTIVE STUDIES;

EID: 84861153800     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2011.05.028     Document Type: Article

References (14)

1. Moviat M., van Haren F., van der H.H. Conventional or physicochemical approach in intensive care unit patients with metabolic acidosis. Crit Care 2003, 7:R41-R45.
2. Stewart P.A. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol 1983, 61:1444-1461.
3. Kellum J.A. Determinants of blood pH in health and disease. Crit Care 2000, 4:6-14.
4. Rocktaeschel J., Morimatsu H., Uchino S., Goldsmith D., Poustie S., Story D., et al. Acid-base status of critically ill patients with acute renal failure: analysis based on Stewart-Figge methodology. Crit Care 2003, 7:R60.
5. Ring T., Frische S., Nielsen S. Clinical review: renal tubular acidosis-a physicochemical approach. Crit Care 2005, 9:573-580.
6. Koeppen B.M. The kidney and acid-base regulation. Adv Physiol Educ 2009, 33:275-281.
7. Koch S.M., Taylor R.W. Chloride ion in intensive care medicine. Crit Care Med 1992, 20:227-240.
8. Kim G.H., Han J.S., Kim Y.S., Joo K.W., Kim S., Lee J.S. Evaluation of urine acidification by urine anion gap and urine osmolal gap in chronic metabolic acidosis. Am J Kidney Dis 1996, 27:42-47.
9. Liborio A.B., da Silva A.C., Noritomi D.T., Andrade L., Seguro A.C. Impact of chloride balance in acidosis control: the Stewart approach in hemodialysis critically ill patients. J Crit Care 2006, 21:333-338.
10. Kirschbaum B. Sulfate regulation: native kidney vs dialysis. Int J Artif Organs 1999, 22:591-592.
11. Moviat M., Terpstra A.M., Ruitenbeek W., Kluijtmans L.A., Pickkers P., van der Hoeven J.G. Contribution of various metabolites to the "unmeasured" anions in critically ill patients with metabolic acidosis. Crit Care Med 2008, 36:752-758.
12. Noritomi D.T., Soriano F.G., Kellum J.A., Cappi S.B., Biselli P.J., Liborio A.B., et al. Metabolic acidosis in patients with severe sepsis and septic shock: a longitudinal quantitative study. Crit Care Med 2009, 37:2733-2739.
13. Story D.A., Morimatsu H., Bellomo R. Strong ions, weak acids and base excess: a simplified Fencl-Stewart approach to clinical acid-base disorders. Br J Anaesth 2004, 92:54-60.
14. Durward A., Skellett S., Mayer A., Taylor D., Tibby S.M., Murdoch I.A. The value of the chloride: sodium ratio in differentiating the aetiology of metabolic acidosis. Intensive Care Med 2001, 27:828-835.