Exogenous surfactant may improve oxygenation but not mortality in adult patients with acute lung injury/acute respiratory distress syndrome: A meta-analysis of 9 clinical trials

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 26, Issue 5, 2012, Pages 849-856

  Meng, Haoyu ^a,b   Sun, Ying ^b   Lu, Jun ^a   Fu, Shukun ^a   Meng, Zhaoyi ^c   Scott, Melanie ^d   Li, Quan ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c Department of Ophthalmology   (China)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

adverse effects; exogenous surfactant; pulmonary surfactant; randomized control trial

Indexed keywords

ARTIFICIAL LUNG SURFACTANT; LUSUPULTIDE;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTERIAL OXYGEN TENSION; ARTIFICIAL VENTILATION; BRADYCARDIA; HUMAN; HYPOTENSION; HYPOXIA; META ANALYSIS; MORTALITY; OUTCOME ASSESSMENT; OXYGENATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TREATMENT DURATION; TREATMENT RESPONSE;

EID: 84861120862     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2011.11.006     Document Type: Article

References (20)

1. A. Günther, C. Ruppert, R. Schmidt Surfactant alteration and replacement in acute respiratory distress syndrome Respir Res 2 2001 353 364
2. National Heart and Lung Institute, Task Force on Problems Research Approaches, Needs: The Lung Program 1972 Department of Health, Education, and Welfare Washington, DC 165 180
3. J.F. Lewis, R. Veldhuizen The role of exogenous surfactant in the treatment of acute lung injury Annu Rev Physiol 65 2003 613 642
4. J.F. Lewis, A. Brackenbury Role of exogenous surfactant in acute lung injury Crit Care Med 31 suppl 2003 S324 S328
5. D. Walmrath, F. Grimminger, D. Pappert Bronchoscopic administration of bovine natural surfactant in ARDS and septic shock: Impact on gas exchange and haemodynamics Eur Respir J 19 2002 805 810
6. A. Bautin, G. Khubulava, I. Kozlov Surfactant therapy for patients with ARDS after cardiac surgery J Liposome Res 16 2006 265 272
7. W.J. Davidson, D. Dorscheid, R. Spragg Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: Results of a meta-analysis Crit Care 10 2006 R41
8. J.G. Weg, R.A. Balk, R.S. Tharratt Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome JAMA 272 1994 1433 1438
9. A. Anzueto, R.P. Baughman, K.K. Guntupalli Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group N Engl J Med 334 1996 1417 1421
10. T.J. Gregory, K.P. Steinberg, R. Spragg Bovine surfactant therapy for patients with acute respiratory distress syndrome Am J Respir Crit Care Med 155 1997 1309 1315
11. R.G. Spragg, J.F. Lewis, W. Wurst Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant Am J Respir Crit Care Med 167 2003 1562 1566
12. R.G. Spragg, J.F. Lewis, H.D. Walmrath Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome N Engl J Med 351 2004 884 892
13. P. Markart, C. Ruppert, M. Wygrecka Patients with ARDS show improvement but not normalisation of alveolar surface activity with surfactant treatment: Putative role of neutral lipids Thorax 62 2007 588 594
14. I. Tsangaris, E. Galiatsou, E. Kostanti The effect of exogenous surfactant in patients with lung contusions and acute lung injury Intensive Care Med 33 2007 851 855
15. J. Kesecioglu, R. Beale, T.E. Stewart Exogenous natural surfactant for treatment of acute lung injury and the acute respiratory distress syndrome Am J Respir Crit Care Med 180 2009 989 994
16. R.G. Spragg, F.J. Taut, J.F. Lewis Recombinant surfactant protein C-based surfactant for patients with severe direct lung injury Am J Respir Crit Care Med 183 2011 1055 1061
17. N. Seger, R. Soll Animal derived surfactant extract for treatment of respiratory distress syndrome Cochrane Database Syst Rev 15 2009 CD007836
18. M. Duffett, K. Choong, V. Ng Surfactant therapy for acute respiratory failure in children: A systematic review and meta-analysis Crit Care 11 2007 R66
19. F.J. Taut, G. Rippin, P. Schenk A search for subgroups of patients with ARDS who may benefit from surfactant replacement therapy: A pooled analysis of five studies with recombinant surfactant protein-C surfactant (Venticute) Chest 134 2008 724 732
20. B.B. Li, Z.N. Ding The replacement therapy of pulmonary surfactant for ARDS International Journal of Anesthesiology and Resuscitation 25 2004 14 16