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Volumn 16, Issue 3, 2012, Pages 207-216

Spinal cord injury pain: Mechanisms and management

Author keywords

Allodynia; Mechanisms; Musculoskeletal pain; Neuropathic pain; Spinal cord injury; Treatment

Indexed keywords

BACLOFEN; CLONIDINE; DIPHENHYDRAMINE; DRONABINOL; DULOXETINE; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEGA CONOTOXIN MVIIA; OPIATE DERIVATIVE; PLACEBO; PREGABALIN; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 84861097467     PISSN: 15313433     EISSN: 15343081     Source Type: Journal    
DOI: 10.1007/s11916-012-0259-x     Document Type: Review
Times cited : (154)

References (99)
  • 1
    • 65949120926 scopus 로고    scopus 로고
    • Prevalence of chronic pain after traumatic spinal cord injury: A systematic review
    • Dijkers M, Bryce T, Zanca J. Prevalence of chronic pain after traumatic spinal cord injury: a systematic review. J Rehabil Res Dev. 2009;46:13-29.
    • (2009) J Rehabil Res Dev , vol.46 , pp. 13-29
    • Dijkers, M.1    Bryce, T.2    Zanca, J.3
  • 2
    • 79952049476 scopus 로고    scopus 로고
    • A longitudinal study of depression from 1 to 5 years after spinal cord injury
    • Hoffman JM, Bombardier CH, Graves DE, et al. A longitudinal study of depression from 1 to 5 years after spinal cord injury. Arch Phys Med Rehabil. 2011;92:411-8.
    • (2011) Arch Phys Med Rehabil , vol.92 , pp. 411-418
    • Hoffman, J.M.1    Bombardier, C.H.2    Graves, D.E.3
  • 3
    • 81855224824 scopus 로고    scopus 로고
    • Life satisfaction in people with spinal cord injury during the first five years after discharge from inpatient rehabilitation
    • van Leeuwen CM, Post MW, van Asbeck FW, et al. Life satisfaction in people with spinal cord injury during the first five years after discharge from inpatient rehabilitation. Disabil Rehabil. 2012;34:76-83.
    • (2012) Disabil Rehabil , vol.34 , pp. 76-83
    • Van Leeuwen, C.M.1    Post, M.W.2    Van Asbeck, F.W.3
  • 4
    • 33644659288 scopus 로고    scopus 로고
    • International standards for neurological classification of spinal cord injury
    • Marino RJ, Barros T, Biering-Sorensen F, et al. International standards for neurological classification of spinal cord injury. J Spinal Cord Med. 2003;26 Suppl 1:S50-6.
    • (2003) J Spinal Cord Med , vol.26 , Issue.SUPPL. 1
    • Marino, R.J.1    Barros, T.2    Biering-Sorensen, F.3
  • 5
    • 84870805301 scopus 로고    scopus 로고
    • International Spinal Cord Injury Pain (ISCIP) Classification: Part I. Background and description
    • In press
    • Bryce TN, Biering-Sorensen F, Finnerup NB, et al.: International Spinal Cord Injury Pain (ISCIP) Classification: Part I. Background and Description. Spinal Cord 2011, In press.
    • (2011) Spinal Cord
    • Bryce, T.N.1    Biering-Sorensen, F.2    Finnerup, N.B.3
  • 6
    • 0002449491 scopus 로고    scopus 로고
    • Pain following spinal cord injury: Clinical features, prevalence, and taxonomy
    • Siddall PJ, Yezierski RP, Loeser JD: Pain following spinal cord injury: clinical features, prevalence, and taxonomy. IASP newsletter 2000, Available at http://www.iasp-pain.org/TC00-3.html.
    • (2000) IASP Newsletter
    • Siddall, P.J.1    Yezierski, R.P.2    Loeser, J.D.3
  • 7
    • 57349178116 scopus 로고    scopus 로고
    • The international spinal cord injury pain basic data set
    • Widerstrom-Noga E, Biering-Sorensen F, Bryce T, et al. The International Spinal Cord Injury Pain Basic Data Set. Spinal Cord. 2008;46:818-23.
    • (2008) Spinal Cord , vol.46 , pp. 818-823
    • Widerstrom-Noga, E.1    Biering-Sorensen, F.2    Bryce, T.3
  • 8
    • 77949275171 scopus 로고    scopus 로고
    • Reliability and validity of the International Spinal Cord Injury Basic Pain Data Set items as self-report measures
    • Jensen MP, Widerstrom-Noga E, Richards JS, et al. Reliability and validity of the International Spinal Cord Injury Basic Pain Data Set items as self-report measures. Spinal Cord. 2010;48:230-8.
    • (2010) Spinal Cord , vol.48 , pp. 230-238
    • Jensen, M.P.1    Widerstrom-Noga, E.2    Richards, J.S.3
  • 10
    • 0037683297 scopus 로고    scopus 로고
    • A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury
    • DOI 10.1016/S0304-3959(02)00452-9
    • Siddall PJ, McClelland JM, Rutkowski SB, Cousins MJ. A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury. Pain. 2003;103:249-57. (Pubitemid 36638814)
    • (2003) Pain , vol.103 , Issue.3 , pp. 249-257
    • Siddall, P.J.1    McClelland, J.M.2    Rutkowski, S.B.3    Cousins, M.J.4
  • 11
    • 80053053333 scopus 로고    scopus 로고
    • A cross-sectional study of demographic and morphologic features of rotator cuff disease in paraplegic patients
    • Akbar M, Brunner M, Balean G, et al. A cross-sectional study of demographic and morphologic features of rotator cuff disease in paraplegic patients. J Shoulder Elbow Surg. 2011;20:1108-13.
    • (2011) J Shoulder Elbow Surg , vol.20 , pp. 1108-1113
    • Akbar, M.1    Brunner, M.2    Balean, G.3
  • 12
    • 40449129186 scopus 로고    scopus 로고
    • Abdominal pain in long-term spinal cord injury
    • DOI 10.1038/sj.sc.3102097, PII 3102097
    • Finnerup NB, Faaborg P, Krogh K, Jensen TS. Abdominal pain in long-term spinal cord injury. Spinal Cord. 2008;46:198-203. (Pubitemid 351347925)
    • (2008) Spinal Cord , vol.46 , Issue.3 , pp. 198-203
    • Finnerup, N.B.1    Faaborg, P.2    Krogh, K.3    Jensen, T.S.4
  • 13
    • 34247209276 scopus 로고    scopus 로고
    • Pain following spinal cord injury
    • McMahon SB, Koltzenburg M, editors. Churchill Livingstone: Elsevier
    • Siddall PJ. Pain following spinal cord injury. In: McMahon SB, Koltzenburg M, editors. Textbook of pain. Churchill Livingstone: Elsevier; 2006. p. 1043-55.
    • (2006) Textbook of Pain , pp. 1043-1055
    • Siddall, P.J.1
  • 14
    • 80053180821 scopus 로고    scopus 로고
    • A new definition of neuropathic pain
    • Jensen TS, Baron R, Haanpaa M, et al. A new definition of neuropathic pain. Pain. 2011;152:2204-5.
    • (2011) Pain , vol.152 , pp. 2204-2205
    • Jensen, T.S.1    Baron, R.2    Haanpaa, M.3
  • 15
    • 70449622719 scopus 로고    scopus 로고
    • Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury
    • Carlton SM, Du J, Tan HY, et al. Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury. Pain. 2009;147:265-76.
    • (2009) Pain , vol.147 , pp. 265-276
    • Carlton, S.M.1    Du, J.2    Tan, H.Y.3
  • 16
    • 78651457235 scopus 로고    scopus 로고
    • Above-level mechanical hyperalgesia in rats develops after incomplete spinal cord injury but not after cord transection, and is reversed by amitriptyline, morphine and gabapentin
    • Densmore VS, Kalous A, Keast JR, Osborne PB. Above-level mechanical hyperalgesia in rats develops after incomplete spinal cord injury but not after cord transection, and is reversed by amitriptyline, morphine and gabapentin. Pain. 2010;151:184-93.
    • (2010) Pain , vol.151 , pp. 184-193
    • Densmore, V.S.1    Kalous, A.2    Keast, J.R.3    Osborne, P.B.4
  • 17
    • 84870840867 scopus 로고    scopus 로고
    • Evoked potentials and quantitative thermal testing in spinal cord injury patients with chronic neuropathic pain
    • Epub Aug 16
    • Kumru H, Soler D, Vidal J, et al.: Evoked potentials and quantitative thermal testing in spinal cord injury patients with chronic neuropathic pain. Clin Neurophysiol 2011, Epub Aug 16
    • (2011) Clin Neurophysiol
    • Kumru, H.1    Soler, D.2    Vidal, J.3
  • 18
    • 84870812306 scopus 로고    scopus 로고
    • The nature and course of sensory changes following spinal cord injury: Predictive properties and implications on the mechanism of central pain
    • Epub Nov 16
    • Zeilig G, Enosh S, Rubin-Asher D, et al.: The nature and course of sensory changes following spinal cord injury: predictive properties and implications on the mechanism of central pain. Brain 2011, Epub Nov 16.
    • (2011) Brain
    • Zeilig, G.1    Enosh, S.2    Rubin-Asher, D.3
  • 20
    • 78650415128 scopus 로고    scopus 로고
    • NeuPSIG guidelines on neuropathic pain assessment
    • Haanpaa M, Attal N, Backonja M, et al. NeuPSIG guidelines on neuropathic pain assessment. Pain. 2011;152:14-27.
    • (2011) Pain , vol.152 , pp. 14-27
    • Haanpaa, M.1    Attal, N.2    Backonja, M.3
  • 22
    • 85047697444 scopus 로고    scopus 로고
    • Pain classification following spinal cord injury: The utility of verbal descriptors
    • DOI 10.1038/sj/sc/3101269
    • Putzke JD, Richards JS, Hicken BL, et al. Pain classification following spinal cord injury: The utility of verbal descriptors. Spinal Cord. 2002;40:118-27. (Pubitemid 34188277)
    • (2002) Spinal Cord , vol.40 , Issue.3 , pp. 118-127
    • Putzke, J.D.1    Richards, J.S.2    Hicken, B.L.3    Ness, T.J.4    Kezar, L.5    DeVivo, M.6
  • 24
    • 79953048654 scopus 로고    scopus 로고
    • Screening tools for neuropathic pain: Can they be of use in individuals with spinal cord injury?
    • Hallstrom H, Norrbrink C. Screening tools for neuropathic pain: can they be of use in individuals with spinal cord injury? Pain. 2011;152:772-9.
    • (2011) Pain , vol.152 , pp. 772-779
    • Hallstrom, H.1    Norrbrink, C.2
  • 25
    • 79961209828 scopus 로고    scopus 로고
    • Conditioned place preference reveals tonic pain in an animal model of central pain
    • Davoody L, Quiton RL, Lucas JM, et al. Conditioned place preference reveals tonic pain in an animal model of central pain. J Pain. 2011;12:868-74.
    • (2011) J Pain , vol.12 , pp. 868-874
    • Davoody, L.1    Quiton, R.L.2    Lucas, J.M.3
  • 26
    • 78049465524 scopus 로고    scopus 로고
    • Reflex and pain behaviors are not equivalent: Lessons from spinal cord injury
    • Yezierski RP, Vierck CJ. Reflex and pain behaviors are not equivalent: lessons from spinal cord injury. Pain. 2010;151:569-70.
    • (2010) Pain , vol.151 , pp. 569-570
    • Yezierski, R.P.1    Vierck, C.J.2
  • 27
    • 36249031078 scopus 로고    scopus 로고
    • Gabapentin suppresses spasticity in the spinal cord-injured rat
    • DOI 10.1016/j.neuroscience.2007.07.020, PII S0306452207009037
    • Kitzman PH, Uhl TL, Dwyer MK. Gabapentin suppresses spasticity in the spinal cord-injured rat. Neuroscience. 2007;149:813-21. (Pubitemid 350123753)
    • (2007) Neuroscience , vol.149 , Issue.4 , pp. 813-821
    • Kitzman, P.H.1    Uhl, T.L.2    Dwyer, M.K.3
  • 28
    • 78049477607 scopus 로고    scopus 로고
    • Spinal-, brainstem- and cerebrally mediated responses at- and below-level of a spinal cord contusion in rats: Evaluation of pain-like behavior
    • Baastrup C, Maersk-Moller CC, Nyengaard JR, et al. Spinal-, brainstem- and cerebrally mediated responses at- and below-level of a spinal cord contusion in rats: evaluation of pain-like behavior. Pain. 2010;151:670-9.
    • (2010) Pain , vol.151 , pp. 670-679
    • Baastrup, C.1    Maersk-Moller, C.C.2    Nyengaard, J.R.3
  • 29
    • 79955919643 scopus 로고    scopus 로고
    • Neuronal hyperexcitability: A substrate for central neuropathic pain after spinal cord injury
    • Gwak YS, Hulsebosch CE. Neuronal hyperexcitability: a substrate for central neuropathic pain after spinal cord injury. Curr Pain Headache Rep. 2011;15:215-22.
    • (2011) Curr Pain Headache Rep , vol.15 , pp. 215-222
    • Gwak, Y.S.1    Hulsebosch, C.E.2
  • 30
    • 79957959515 scopus 로고    scopus 로고
    • Cellular and molecular insights into neuropathy-induced pain hypersensitivity for mechanism-based treatment approaches
    • Berger JV, Knaepen L, Janssen SP, et al. Cellular and molecular insights into neuropathy-induced pain hypersensitivity for mechanism-based treatment approaches. Brain Res Rev. 2011;67: 282-310.
    • (2011) Brain Res Rev , vol.67 , pp. 282-310
    • Berger, J.V.1    Knaepen, L.2    Janssen, S.P.3
  • 31
    • 84859900673 scopus 로고    scopus 로고
    • The dark side of neuroplasticity
    • Epub Nov 12
    • Brown A, Weaver LC: The dark side of neuroplasticity. Exp Neurol. 2011, Epub Nov 12
    • (2011) Exp Neurol
    • Brown, A.1    Weaver, L.C.2
  • 32
    • 70350289958 scopus 로고    scopus 로고
    • Dendritic spine remodeling after spinal cord injury alters neuronal signal processing
    • Tan AM, Choi JS, Waxman SG, Hains BC. Dendritic spine remodeling after spinal cord injury alters neuronal signal processing. J Neurophysiol. 2009;102:2396-409.
    • (2009) J Neurophysiol , vol.102 , pp. 2396-2409
    • Tan, A.M.1    Choi, J.S.2    Waxman, S.G.3    Hains, B.C.4
  • 33
    • 84859900672 scopus 로고    scopus 로고
    • Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms
    • Epub Sept 7
    • Tan AM, Waxman SG: Spinal cord injury, dendritic spine remodeling, and spinal memory mechanisms. Exp Neurol. 2011, Epub Sept 7
    • (2011) Exp Neurol
    • Tan, A.M.1    Waxman, S.G.2
  • 34
    • 34347389235 scopus 로고    scopus 로고
    • Sodium channel expression and the molecular pathophysiology of pain after SCI
    • DOI 10.1016/S0079-6123(06)61013-3, PII S0079612306610133
    • Hains BC, Waxman SG: Sodium channel expression and the molecular pathophysiology of pain after SCI. Prog Brain Res. 2007;161:195-203.:195-203 (Pubitemid 47023093)
    • (2007) Progress in Brain Research , vol.161 , pp. 195-203
    • Hains, B.C.1    Waxman, S.G.2
  • 35
    • 79851507524 scopus 로고    scopus 로고
    • Calcium channel alpha-2- delta-1 protein upregulation in dorsal spinal cord mediates spinal cord injury-induced neuropathic pain states
    • Boroujerdi A, Zeng J, Sharp K, et al. Calcium channel alpha-2- delta-1 protein upregulation in dorsal spinal cord mediates spinal cord injury-induced neuropathic pain states. Pain. 2011;152:649-55.
    • (2011) Pain , vol.152 , pp. 649-655
    • Boroujerdi, A.1    Zeng, J.2    Sharp, K.3
  • 36
    • 77953689502 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors contribute to maintained neuronal hyperexcitability following spinal cord injury in rats
    • Leem JW, Kim HK, Hulsebosch CE, Gwak YS. Ionotropic glutamate receptors contribute to maintained neuronal hyperexcitability following spinal cord injury in rats. Exp Neurol. 2010;224:321-4.
    • (2010) Exp Neurol , vol.224 , pp. 321-324
    • Leem, J.W.1    Kim, H.K.2    Hulsebosch, C.E.3    Gwak, Y.S.4
  • 37
    • 78049513095 scopus 로고    scopus 로고
    • Chronic spontaneous activity generated in the somata of primary nociceptors is associated with pain-related behavior after spinal cord injury
    • Bedi SS, Yang Q, Crook RJ, et al. Chronic spontaneous activity generated in the somata of primary nociceptors is associated with pain-related behavior after spinal cord injury. J Neurosci. 2010;30: 14870-82.
    • (2010) J Neurosci , vol.30 , pp. 14870-14882
    • Bedi, S.S.1    Yang, Q.2    Crook, R.J.3
  • 38
    • 33646439133 scopus 로고    scopus 로고
    • Activated microglia contribute to the maintenance of chronic pain after spinal cord injury
    • DOI 10.1523/JNEUROSCI.0003-06.2006
    • Hains BC, Waxman SG. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J Neurosci. 2006;26:4308-17. (Pubitemid 44315390)
    • (2006) Journal of Neuroscience , vol.26 , Issue.16 , pp. 4308-4317
    • Hains, B.C.1    Waxman, S.G.2
  • 39
    • 84861093171 scopus 로고    scopus 로고
    • Spatial and temporal activation of spinal glial cells: Role of gliopathy in central neuropathic pain following spinal cord injury in rats
    • Epub Oct 21
    • Gwak YS, Kang J, Unabia GC, Hulsebosch CE: Spatial and temporal activation of spinal glial cells: Role of gliopathy in central neuropathic pain following spinal cord injury in rats. Exp Neurol. 2011, Epub Oct 21.
    • (2011) Exp Neurol
    • Gwak, Y.S.1    Kang, J.2    Unabia, G.C.3    Hulsebosch, C.E.4
  • 40
    • 34548096949 scopus 로고    scopus 로고
    • Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine-cysteine chemokine ligand 21
    • DOI 10.1523/JNEUROSCI.2209-07.2007
    • Zhao P, Waxman SG, Hains BC. Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand. J Neurosci. 2007;27:8893-902. (Pubitemid 47292772)
    • (2007) Journal of Neuroscience , vol.27 , Issue.33 , pp. 8893-8902
    • Zhao, P.1    Waxman, S.G.2    Hains, B.C.3
  • 41
    • 60949105934 scopus 로고    scopus 로고
    • CCL2 is a key mediator of microglia activation in neuropathic pain states
    • Thacker MA, Clark AK, Bishop T, et al. CCL2 is a key mediator of microglia activation in neuropathic pain states. Eur J Pain. 2009;13:263-72.
    • (2009) Eur J Pain , vol.13 , pp. 263-272
    • Thacker, M.A.1    Clark, A.K.2    Bishop, T.3
  • 42
    • 79955634824 scopus 로고    scopus 로고
    • Spatiotemporal CCR1 CCL3(MIP-1alpha) CXCR4 CXCL12(SDF-1alpha) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain
    • Knerlich-Lukoschus F, von der R-B, Lucius R, et al. Spatiotemporal CCR1, CCL3(MIP-1alpha), CXCR4, CXCL12(SDF-1alpha) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain. J Neurosurg Spine. 2011;14:583-97.
    • (2011) J Neurosurg Spine , vol.14 , pp. 583-597
    • Knerlich-Lukoschus, F.1    Von Der, R.-B.2    Lucius R, R.3
  • 43
    • 79954430475 scopus 로고    scopus 로고
    • Upregulation of inflammatory mediators in a model of chronic pain after spinal cord injury
    • Sandhir R, Gregory E, He YY, Berman NE. Upregulation of inflammatory mediators in a model of chronic pain after spinal cord injury. Neurochem Res. 2011;36:856-62.
    • (2011) Neurochem Res , vol.36 , pp. 856-862
    • Sandhir, R.1    Gregory, E.2    He, Y.Y.3    Berman, N.E.4
  • 44
    • 79952313732 scopus 로고    scopus 로고
    • GABA and central neuropathic pain following spinal cord injury
    • Gwak YS, Hulsebosch CE. GABA and central neuropathic pain following spinal cord injury. Neuropharmacology. 2011;60:799-808.
    • (2011) Neuropharmacology , vol.60 , pp. 799-808
    • Gwak, Y.S.1    Hulsebosch, C.E.2
  • 45
    • 77951294191 scopus 로고    scopus 로고
    • Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury
    • Meisner JG, Marsh AD, Marsh DR. Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury. J Neurotrauma. 2010;27:729-37.
    • (2010) J Neurotrauma , vol.27 , pp. 729-737
    • Meisner, J.G.1    Marsh, A.D.2    Marsh, D.R.3
  • 46
    • 77954585902 scopus 로고    scopus 로고
    • Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury
    • Hasbargen T, Ahmed MM, Miranpuri G, et al.: Role of NKCC1 and KCC2 in the development of chronic neuropathic pain following spinal cord injury. Ann N YAcad Sci. 2010;1198:168-72.:168-172.
    • (2010) Ann N YAcad Sci , vol.1198 , Issue.168-172 , pp. 168-172
    • Hasbargen, T.1    Ahmed, M.M.2    Miranpuri, G.3
  • 47
    • 53549122751 scopus 로고    scopus 로고
    • The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury
    • Cramer SW, Baggott C, Cain J, et al.: The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury. Mol Pain. 2008;4
    • (2008) Mol Pain , vol.4
    • Cramer, S.W.1    Baggott, C.2    Cain, J.3
  • 48
    • 84861092003 scopus 로고    scopus 로고
    • Subarachnoid transplant of the human neuronal hNT2.19 serotonergic cell line attenuates behavioral hypersensitivity without affecting motor dysfunction after severe contusive spinal cord injury
    • ID 891605
    • EatonMJ,Widerstrom-Noga E,Wolfe SQ: Subarachnoid transplant of the human neuronal hNT2.19 serotonergic cell line attenuates behavioral hypersensitivity without affecting motor dysfunction after severe contusive spinal cord injury. Neurol Res Int. 2011;2011:ID 891605
    • (2011) Neurol Res Int , vol.2011
    • Eaton, M.J.1    Widerstrom-Noga, E.2    Wolfe, S.Q.3
  • 49
    • 65949093032 scopus 로고    scopus 로고
    • Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats
    • Eaton MJ, Wolfe SQ. Clinical feasibility for cell therapy using human neuronal cell line to treat neuropathic behavioral hypersensitivity following spinal cord injury in rats. J Rehabil Res Dev. 2009;46:145-65.
    • (2009) J Rehabil Res Dev , vol.46 , pp. 145-165
    • Eaton, M.J.1    Wolfe, S.Q.2
  • 50
    • 80055064642 scopus 로고    scopus 로고
    • Treatment of rat spinal cord injury with the neurotrophic factor albumin-oleic Acid: Translational application for paralysis, spasticity and pain
    • Avila-Martin G, Galan-Arriero I, Gomez-Soriano J, Taylor J. Treatment of rat spinal cord injury with the neurotrophic factor albumin-oleic Acid: translational application for paralysis, spasticity and pain. PLoS One. 2011;6:e26107.
    • (2011) PLoS One , vol.6
    • Avila-Martin, G.1    Galan-Arriero, I.2    Gomez-Soriano, J.3    Taylor, J.4
  • 51
    • 0036895397 scopus 로고    scopus 로고
    • Laser-evoked potential abnormalities in central pain patients: The influence of spontaneous and provoked pain
    • Garcia-Larrea L, Convers P, Magnin M, et al. Laser-evoked potential abnormalities in central pain patients: the influence of spontaneous and provoked pain. Brain. 2002;125:2766-81. (Pubitemid 35423525)
    • (2002) Brain , vol.125 , Issue.12 , pp. 2766-2781
    • Garcia-Larrea, L.1    Convers, P.2    Magnin, M.3    Andre-Obadia, N.4    Peyron, R.5    Laurent, B.6    Mauguiere, F.7
  • 52
    • 0018084750 scopus 로고
    • Phantom body pain in paraplegics: Evidence for a central 'pattern generating mechanism' for pain
    • DOI 10.1016/0304-3959(77)90133-6
    • Melzack R, Loeser JD. Phantom body pain in paraplegics: evidence for a central "pattern generating mechanism" for pain. Pain. 1978;4:195-210. (Pubitemid 8273224)
    • (1978) Pain , vol.4 , Issue.3 , pp. 195-210
    • Melzack, R.1    Loeser, J.D.2
  • 53
    • 0344738664 scopus 로고    scopus 로고
    • MRI in chronic spinal cord injury patients with and without central pain
    • Finnerup NB, Gyldensted C, Nielsen E, et al. MRI in chronic spinal cord injury patients with and without central pain. Neurology. 2004;61:1569-75.
    • (2004) Neurology , vol.61 , pp. 1569-1575
    • Finnerup, N.B.1    Gyldensted, C.2    Nielsen, E.3
  • 54
    • 0003289302 scopus 로고
    • Central neurogenic pain: Possible mechanisms
    • Willis WD. Central neurogenic pain: possible mechanisms. Adv Pain Res Ther. 1991;19:81-102.
    • (1991) Adv Pain Res Ther , vol.19 , pp. 81-102
    • Willis, W.D.1
  • 57
    • 77956059949 scopus 로고    scopus 로고
    • Neuro magnetic resonance spectroscopy using wavelet decomposition and statistical testing identifies biochemical changes in people with spinal cord injury and pain
    • Stanwell P, Siddall P, Keshava N, et al. Neuro magnetic resonance spectroscopy using wavelet decomposition and statistical testing identifies biochemical changes in people with spinal cord injury and pain. Neuroimage. 2010;53:544-52.
    • (2010) Neuroimage , vol.53 , pp. 544-552
    • Stanwell, P.1    Siddall, P.2    Keshava, N.3
  • 58
    • 58149163278 scopus 로고    scopus 로고
    • Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury
    • Wrigley PJ, Press SR, Gustin SM, et al. Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury. Pain. 2009;141:52-9.
    • (2009) Pain , vol.141 , pp. 52-59
    • Wrigley, P.J.1    Press, S.R.2    Gustin, S.M.3
  • 59
    • 84861101680 scopus 로고    scopus 로고
    • Are we neglecting spinal reorganization following nerve damage?
    • Epub Nov 18
    • Finnerup NB, Nikolajsen L, Jensen TS: Are we neglecting spinal reorganization following nerve damage? Pain. 2011;Epub Nov 18
    • (2011) Pain
    • Finnerup, N.B.1    Nikolajsen, L.2    Jensen, T.S.3
  • 60
    • 0001046549 scopus 로고
    • Pain resulting from central nervous system pathology (central pain)
    • Bonica JJ, editor. Philadelphia: LEA & FEBIGER;
    • Tasker R. Pain resulting from central nervous system pathology (central pain). In: Bonica JJ, editor. The management of pain. Philadelphia: LEA & FEBIGER; 1990. p. 264-83.
    • (1990) The Management of Pain , pp. 264-283
    • Tasker, R.1
  • 62
    • 0035130326 scopus 로고    scopus 로고
    • Characterization of chronic pain and somatosensory function in spinal cord injury subjects
    • DOI 10.1016/S0304-3959(00)00369-9, PII S0304395900003699
    • Defrin R, Ohry A, Blumen N, Urca G. Characterization of chronic pain and somatosensory function in spinal cord injury subjects. Pain. 2001;89:253-63. (Pubitemid 32146405)
    • (2001) Pain , vol.89 , Issue.2-3 , pp. 253-263
    • Defrin, R.1    Ohry, A.2    Blumen, N.3    Urca, G.4
  • 63
    • 0037224588 scopus 로고    scopus 로고
    • Sensory function in spinal cord injury patients with and without central pain
    • DOI 10.1093/brain/awg007
    • Finnerup NB, Johannesen IL, Fuglsang-Frederiksen A, et al. Sensory function in spinal cord injury patients with and without central pain. Brain. 2003;126:57-70. (Pubitemid 36068560)
    • (2003) Brain , vol.126 , Issue.1 , pp. 57-70
    • Finnerup, N.B.1    Johannesen, I.L.2    Fuglsang-Frederiksen, A.3    Bach, F.W.4    Jensen, T.S.5
  • 64
    • 67649881618 scopus 로고    scopus 로고
    • Neuropathic pain in spinal cord injury: Significance of clinical and electrophysiological measures
    • Wydenkeller S, Maurizio S, Dietz V, Halder P. Neuropathic pain in spinal cord injury: significance of clinical and electrophysiological measures. Eur J Neurosci. 2009;30:91-9.
    • (2009) Eur J Neurosci , vol.30 , pp. 91-99
    • Wydenkeller, S.1    Maurizio, S.2    Dietz, V.3    Halder, P.4
  • 65
    • 62049083634 scopus 로고    scopus 로고
    • Enhanced recovery of human spinothalamic function is associated with central neuropathic pain after SCI
    • Hari AR, Wydenkeller S, Dokladal P, Halder P. Enhanced recovery of human spinothalamic function is associated with central neuropathic pain after SCI. Exp Neurol. 2009;216:428-30.
    • (2009) Exp Neurol , vol.216 , pp. 428-430
    • Hari, A.R.1    Wydenkeller, S.2    Dokladal, P.3    Halder, P.4
  • 66
    • 50849084474 scopus 로고    scopus 로고
    • Residual spinothalamic tract pathways predict development of central pain after spinal cord injury
    • Wasner G, Lee BB, Engel S, McLachlan E. Residual spinothalamic tract pathways predict development of central pain after spinal cord injury. Brain. 2008;131:2387-400.
    • (2008) Brain , vol.131 , pp. 2387-2400
    • Wasner, G.1    Lee, B.B.2    Engel, S.3    McLachlan, E.4
  • 67
    • 18544411408 scopus 로고    scopus 로고
    • Types and effectiveness of treatments used by people with chronic pain associated with spinal cord injuries: Influence of pain and psychosocial characteristics
    • DOI 10.1038/sj.sc.3101511
    • Widerstrom-Noga EG, Turk DC. Types and effectiveness of treatments used by people with chronic pain associated with spinal cord injuries: influence of pain and psychosocial characteristics. Spinal Cord. 2003;41:600-9. (Pubitemid 37386445)
    • (2003) Spinal Cord , vol.41 , Issue.11 , pp. 600-609
    • Widerstrom-Noga, E.G.1    Turk, D.C.2
  • 68
    • 33749246215 scopus 로고    scopus 로고
    • Treatments for chronic pain in persons with spinal cord injury: A survey study
    • Cardenas DD, Jensen MP. Treatments for chronic pain in persons with spinal cord injury: a survey study. J Spinal Cord Med. 2006;29:109-17.
    • (2006) J Spinal Cord Med , vol.29 , pp. 109-117
    • Cardenas, D.D.1    Jensen, M.P.2
  • 69
    • 79952824018 scopus 로고    scopus 로고
    • Strengthening and optimal movements for painful shoulders (STOMPS) in chronic spinal cord injury: A randomized controlled trial
    • Mulroy SJ, Thompson L, Kemp B, et al. Strengthening and optimal movements for painful shoulders (STOMPS) in chronic spinal cord injury: a randomized controlled trial. Phys Ther. 2011;91:305-24.
    • (2011) Phys Ther , vol.91 , pp. 305-324
    • Mulroy, S.J.1    Thompson, L.2    Kemp, B.3
  • 71
    • 77953823105 scopus 로고    scopus 로고
    • EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision
    • Attal N, Cruccu G, Baron R, et al. EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision. Eur J Neurol. 2010;17:1113-e88.
    • (2010) Eur J Neurol. , vol.17
    • Attal, N.1    Cruccu, G.2    Baron, R.3
  • 72
    • 77950367410 scopus 로고    scopus 로고
    • Recommendations for the pharmacological management of neuropathic pain: An overview and literature update
    • Dworkin RH, O'connor AB, Audette J, et al. Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc. 2010;85:S3-S14.
    • (2010) Mayo Clin Proc , vol.85
    • Dworkin, R.H.1    O'Connor, A.B.2    Audette, J.3
  • 74
    • 78651519971 scopus 로고    scopus 로고
    • Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: A randomized, double-blind, placebo-controlled trial
    • Vranken JH, Hollmann MW, van der Vegt MH, et al. Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: A randomized, double-blind, placebo-controlled trial. Pain. 2010;152:267-73.
    • (2010) Pain , vol.152 , pp. 267-273
    • Vranken, J.H.1    Hollmann, M.W.2    Van Der Vegt, M.H.3
  • 75
    • 33845403623 scopus 로고    scopus 로고
    • Pregabalin in central neuropathic pain associated with spinal cord injury: A placebo-controlled trial
    • DOI 10.1212/01.wnl.0000244422.45278.ff, PII 0000611420061128000017
    • Siddall PJ, Cousins MJ, Otte A, et al. Pregabalin in central neuropathic pain associated with spinal cord injury: a placebo-controlled trial. Neurology. 2006;67:1792-800. (Pubitemid 44900755)
    • (2006) Neurology , vol.67 , Issue.10 , pp. 1792-1800
    • Siddall, P.J.1    Cousins, M.J.2    Otte, A.3    Griesing, T.4    Chambers, R.5    Murphy, T.K.6
  • 76
    • 67649207623 scopus 로고    scopus 로고
    • Tramadol in neuropathic pain after spinal cord injury: A randomized, double-blind, placebocontrolled trial
    • Norrbrink C, Lundeberg T. Tramadol in neuropathic pain after spinal cord injury: a randomized, double-blind, placebocontrolled trial. Clin J Pain. 2009;25:177-84.
    • (2009) Clin J Pain , vol.25 , pp. 177-184
    • Norrbrink, C.1    Lundeberg, T.2
  • 77
    • 4043096916 scopus 로고    scopus 로고
    • Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
    • Svendsen KB, Jensen TS, Bach FW. Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. BMJ. 2004;329:253-61.
    • (2004) BMJ , vol.329 , pp. 253-261
    • Svendsen, K.B.1    Jensen, T.S.2    Bach, F.W.3
  • 78
    • 25444530723 scopus 로고    scopus 로고
    • Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
    • DOI 10.1212/01.wnl.0000176753.45410.8b
    • Rog DJ, Nurmikko TJ, Friede T, Young CA. Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology. 2005;65:812-9. (Pubitemid 41362120)
    • (2005) Neurology , vol.65 , Issue.6 , pp. 812-819
    • Rog, D.J.1    Nurmikko, T.J.2    Friede, T.3    Young, C.A.4
  • 79
    • 78649316038 scopus 로고    scopus 로고
    • Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain
    • Ahmed MM, Rajpal S, Sweeney C, et al. Cannabinoid subtype-2 receptors modulate the antihyperalgesic effect of WIN 55,212-2 in rats with neuropathic spinal cord injury pain. Spine J. 2010;10: 1049-54.
    • (2010) Spine J , vol.10 , pp. 1049-1054
    • Ahmed, M.M.1    Rajpal, S.2    Sweeney, C.3
  • 80
    • 80052026180 scopus 로고    scopus 로고
    • Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a ratmodel of neuropathic spinal cord injury pain
    • Hama A, Sagen J.Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a ratmodel of neuropathic spinal cord injury pain. Brain Res. 2011;1412:44-54.
    • (2011) Brain Res , vol.1412 , pp. 44-54
    • Hama, A.1    Sagen, J.2
  • 81
    • 77957567663 scopus 로고    scopus 로고
    • Effect of dronabinol on central neuropathic pain after spinal cord injury: A pilot study
    • Rintala DH, Fiess RN, Tan G, et al. Effect of dronabinol on central neuropathic pain after spinal cord injury: a pilot study. Am J Phys Med Rehabil. 2010;89:840-8.
    • (2010) Am J Phys Med Rehabil , vol.89 , pp. 840-848
    • Rintala, D.H.1    Fiess, R.N.2    Tan, G.3
  • 82
    • 0033677167 scopus 로고    scopus 로고
    • The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury
    • Siddall PJ, Molloy AR, Walker S, Rutkowski SB. The efficacy of intrathecal morphine and clonidine in the treatment of pain after spinal cord injury. Anesth Analg. 2000;91:1-6.
    • (2000) Anesth Analg , vol.91 , pp. 1-6
    • Siddall, P.J.1    Molloy, A.R.2    Walker, S.3    Rutkowski, S.B.4
  • 83
    • 67650459927 scopus 로고    scopus 로고
    • Intrathecal ziconotide and baclofen provide pain relief in seven patients with neuropathic pain and spasticity: Case reports
    • Saulino M, Burton AW, Danyo DA, et al. Intrathecal ziconotide and baclofen provide pain relief in seven patients with neuropathic pain and spasticity: case reports. Eur J Phys Rehabil Med. 2009;45: 61-7.
    • (2009) Eur J Phys Rehabil Med , vol.45 , pp. 61-67
    • Saulino, M.1    Burton, A.W.2    Danyo, D.A.3
  • 84
    • 84861100179 scopus 로고    scopus 로고
    • Simultaneous treatment of intractable pain and spasticity: Observations of combined intrathecal baclofen-morphine therapy over a 10-year clinical experience
    • Epub April 28
    • SaulinoM: Simultaneous treatment of intractable pain and spasticity: observations of combined intrathecal baclofen-morphine therapy over a 10-year clinical experience. Eur J Phys Rehabil Med. 2011, Epub April 28
    • (2011) Eur J Phys Rehabil Med
    • Saulino, M.1
  • 85
    • 67349196056 scopus 로고    scopus 로고
    • The chronic neuropathic pain of spinal cord injury: Which efficiency of neuropathic stimulation?
    • Lagauche D, Facione J, Albert T, Fattal C. The chronic neuropathic pain of spinal cord injury: which efficiency of neuropathic stimulation? Ann Phys Rehabil Med. 2009;52:180-7.
    • (2009) Ann Phys Rehabil Med , vol.52 , pp. 180-187
    • Lagauche, D.1    Facione, J.2    Albert, T.3    Fattal, C.4
  • 86
    • 65249109373 scopus 로고    scopus 로고
    • Chronic neuropathic pain in spinal cord injury: Efficiency of deep brain and motor cortex stimulation therapies for neuropathic pain in spinal cord injury patients
    • Previnaire JG, Nguyen JP, Perrouin-Verbe B, Fattal C. Chronic neuropathic pain in spinal cord injury: efficiency of deep brain and motor cortex stimulation therapies for neuropathic pain in spinal cord injury patients. Ann Phys Rehabil Med. 2009;52:188-93.
    • (2009) Ann Phys Rehabil Med , vol.52 , pp. 188-193
    • Previnaire, J.G.1    Nguyen, J.P.2    Perrouin-Verbe, B.3    Fattal, C.4
  • 87
    • 77956389824 scopus 로고    scopus 로고
    • Effectiveness of transcranial direct current stimulation and visual illusion on neuropathic pain in spinal cord injury
    • Soler MD, Kumru H, Pelayo R, et al. Effectiveness of transcranial direct current stimulation and visual illusion on neuropathic pain in spinal cord injury. Brain. 2010;133:2565-77.
    • (2010) Brain , vol.133 , pp. 2565-2577
    • Soler, M.D.1    Kumru, H.2    Pelayo, R.3
  • 88
    • 76349105481 scopus 로고    scopus 로고
    • Brain circuitry underlying pain in response to imagined movement in people with spinal cord injury
    • Gustin SM,Wrigley PJ, Henderson LA, Siddall PJ. Brain circuitry underlying pain in response to imagined movement in people with spinal cord injury. Pain. 2010;148:438-45.
    • (2010) Pain , vol.148 , pp. 438-445
    • Gustin, S.M.1    Wrigley, P.J.2    Henderson, L.A.3    Siddall, P.J.4
  • 89
    • 0036726988 scopus 로고    scopus 로고
    • Dorsal root entry zone microcoagulation for spinal cord injury-related central pain: Operative intramedullary electrophysiological guidance and clinical outcome
    • Falci S, Best L, Bayles R, et al. Dorsal root entry zone microcoagulation for spinal cord injury-related central pain: operative intramedullary electrophysiological guidance and clinical outcome. J Neurosurg. 2002;97:193-200.
    • (2002) J Neurosurg , vol.97 , pp. 193-200
    • Falci, S.1    Best, L.2    Bayles, R.3
  • 90
    • 79956218595 scopus 로고    scopus 로고
    • A modified microsurgical DREZotomy procedure for refractory neuropathic pain
    • Chun HJ, Kim YS, Yi HJ. A modified microsurgical DREZotomy procedure for refractory neuropathic pain. World Neurosurg. 2011; 75:551-7.
    • (2011) World Neurosurg , vol.75 , pp. 551-557
    • Chun, H.J.1    Kim, Y.S.2    Yi, H.J.3
  • 91
    • 68449099265 scopus 로고    scopus 로고
    • Effects of self-hypnosis training and EMG biofeedback relaxation training on chronic pain in persons with spinal-cord injury
    • Jensen MP, Barber J, Romano JM, et al. Effects of self-hypnosis training and EMG biofeedback relaxation training on chronic pain in persons with spinal-cord injury. Int J Clin Exp Hypn. 2009;57:239-68.
    • (2009) Int J Clin Exp Hypn , vol.57 , pp. 239-268
    • Jensen, M.P.1    Barber, J.2    Romano, J.M.3
  • 92
    • 79957600851 scopus 로고    scopus 로고
    • Multidisciplinary cognitive behavioural pain management programmes for people with a spinal cord injury: Design and implementation
    • Perry KN, Nicholas MK, Middleton J. Multidisciplinary cognitive behavioural pain management programmes for people with a spinal cord injury: design and implementation. Disabil Rehabil. 2011;33: 1272-80.
    • (2011) Disabil Rehabil , vol.33 , pp. 1272-1280
    • Perry, K.N.1    Nicholas, M.K.2    Middleton, J.3
  • 93
    • 84870820599 scopus 로고    scopus 로고
    • The CONECSI trial: Results of a randomized controlled trial of a multidisciplinary cognitive behavioral program for coping with chronic neuropathic pain after spinal cord injury
    • Epub Nov 17
    • Heutink M, Post MW, Bongers-Janssen HM, et al.: The CONECSI trial: results of a randomized controlled trial of a multidisciplinary cognitive behavioral program for coping with chronic neuropathic pain after spinal cord injury. Pain. 2011, Epub Nov 17
    • (2011) Pain
    • Heutink, M.1    Post, M.W.2    Bongers-Janssen, H.M.3
  • 94
    • 0036222008 scopus 로고    scopus 로고
    • Efficacy of amitriptyline for relief of pain in spinal cord injury: Results of a randomized controlled trial
    • DOI 10.1016/S0304-3959(01)00483-3, PII S0304395901004833
    • Cardenas DD, Warms CA, Turner JA, et al. Efficacy of amitriptyline for relief of pain in spinal cord injury: results of a randomized controlled trial. Pain. 2002;96:365-73. (Pubitemid 34327885)
    • (2002) Pain , vol.96 , Issue.3 , pp. 365-373
    • Cardenas, D.D.1    Warms, C.A.2    Turner, J.A.3    Marshall, H.4    Brooke, M.M.5    Loeser, J.D.6
  • 95
    • 0036595280 scopus 로고    scopus 로고
    • Gabapentin in the treatment of neuropathic pain after spinal cord injury: A prospective, randomized, double-blind, crossover trial
    • Tai Q, Kirshblum S, Chen B, et al. Gabapentin in the treatment of neuropathic pain after spinal cord injury: a prospective, randomized, double-blind, crossover trial. J Spinal Cord Med. 2002;25: 100-5. (Pubitemid 36834703)
    • (2002) Journal of Spinal Cord Medicine , vol.25 , Issue.2 , pp. 100-105
    • Tai, Q.1    Kirshblum, S.2    Chen, B.3    Millis, S.4    Johnston, M.5    DeLisa, J.A.6
  • 96
    • 1842616051 scopus 로고    scopus 로고
    • Gabapentin Is a First Line Drug for the Treatment of Neuropathic Pain in Spinal Cord Injury
    • DOI 10.1097/01.BRS.0000112068.16108.3A
    • Levendoglu F, Ogun CO, Ozerbil O, et al. Gabapentin is a first line drug for the treatment of neuropathic pain in spinal cord injury. Spine. 2004;29:743-51. (Pubitemid 38437522)
    • (2004) Spine , vol.29 , Issue.7 , pp. 743-751
    • Levendoglu, F.1    Ogun, C.O.2    Ozerbil, O.3    Ogun, T.C.4    Ugurlu, H.5
  • 97
    • 41749093436 scopus 로고    scopus 로고
    • Pregabalin in patients with central neuropathic pain: A randomized, double-blind, placebocontrolled trial of a flexible-dose regimen
    • Vranken JH, Dijkgraaf MG, Kruis RM, et al. Pregabalin in patients with central neuropathic pain: a randomized, double-blind, placebocontrolled trial of a flexible-dose regimen. Pain. 2007;136:150-7.
    • (2007) Pain , vol.136 , pp. 150-157
    • Vranken, J.H.1    Dijkgraaf, M.G.2    Kruis, R.M.3
  • 98
    • 0036213898 scopus 로고    scopus 로고
    • Lamotrigine in spinal cord injury pain: A randomized controlled trial
    • DOI 10.1016/S0304-3959(01)00484-5, PII S0304395901004845
    • Finnerup NB, Sindrup SH, Bach FW, et al. Lamotrigine in spinal cord injury pain: a randomized controlled trial. Pain. 2002;96:375-83. (Pubitemid 34327886)
    • (2002) Pain , vol.96 , Issue.3 , pp. 375-383
    • Finnerup, N.B.1    Sindrup, S.H.2    Bach, F.W.3    Johannesen, I.L.4    Jensen, T.S.5
  • 99
    • 73249135882 scopus 로고    scopus 로고
    • Levetiracetam in spinal cord injury pain: A randomized controlled trial
    • Finnerup NB, Grydehoj J, Bing J, et al. Levetiracetam in spinal cord injury pain: a randomized controlled trial. Spinal Cord. 2009;47:861-7.
    • (2009) Spinal Cord , vol.47 , pp. 861-867
    • Finnerup, N.B.1    Grydehoj, J.2    Bing, J.3


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