Alkylation-induced genotoxicity as a predictor of DNA repair deficiency following experimental oral carcinogenesis

Journal of Molecular Histology

Volumn 43, Issue 2, 2012, Pages 145-150

  Carvalho, Juliana G ^a   Noguti, Juliana ^a   Da Silva, Victor Hugo P ^a   Dedivitis, Rogério A ^b   Franco, Marcello ^a   Ribeiro, Daniel A ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b HOSPITAL ANA COSTA   (Brazil)

Author keywords

4 Nitroquinoline 1 oxide; DNA repair deficiency; Methylmetanesulfonate; Oral squamous cell carcinoma; Rat tongue mucosa

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; DNA; DRINKING WATER; MESYLIC ACID METHYL ESTER;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CELL; BLOOD SAMPLING; CHEMICAL CARCINOGENESIS; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPAIR DEFICIENCY; GENOTOXICITY; HISTOPATHOLOGY; MALE; MOUTH MUCOSA; MOUTH SQUAMOUS CELL CARCINOMA; MUCOSA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; TONGUE CANCER;

4-NITROQUINOLINE-1-OXIDE; ADMINISTRATION, ORAL; ALKYLATION; ANIMALS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; COMET ASSAY; DNA; DNA DAMAGE; DNA REPAIR; DRINKING WATER; LEUKOCYTES, MONONUCLEAR; MALE; METHYL METHANESULFONATE; MOUTH MUCOSA; RATS; RATS, WISTAR; TIME FACTORS; TONGUE NEOPLASMS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84861094090     PISSN: 15672379     EISSN: 15672387     Source Type: Journal    
DOI: 10.1007/s10735-011-9388-5     Document Type: Article

References (27)

1. Anantharaman D, Samant TA, Sen S, Mahimkar MB (2011) Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk. Oral Oncol 47:866-872
2. Assis GF, Ceolin DS, Marques ME, Salvadori DM, Ribeiro DA (2005) Cigarette smoke affects apoptosis in rat tongue mucosa: role of bcl-2 gene family. J Mol Histol 36:483-489 (Pubitemid 43829387)
3. Berwick M, Vineis P (2000) Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review. J Natl Cancer Inst 92:874-897 (Pubitemid 30429188)
4. Fracalossi AC, Miranda SR, Oshima CT, Franco M, Ribeiro DA (2010) The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. J Mol Histol 41:19-25
5. Fracalossi AC, Comparini L, Funabashi K, Godoy C, Iwamura ES, Nascimento FD, Nader HB, Oshima CT, Ribeiro DA (2011) Ras gene mutation is not related to tumour invasion during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. J Oral Pathol Med 40:325-333
6. Haliwell B, Gutteridge J M C (1999) Free radicals in biology and medicine, 3rd edn. Oxford University Press, New York
7. Hartmann A, Agurell E, Beevers C et al (2003) 4th International comet assay workshop. Recommendations for conducting the in vivo alkaline comet assay. Mutagenesis 18:45-51 (Pubitemid 36118820)
8. Hayashi S, Nonoyama T, Miyajima H (1989) Spontaneous nonthymic cell lymphomasin young Wistar rats. Vet Pathol 26:326-332
9. Herzig M, Christofori G (2002) Recent advances in cancer research, mouse models of tumorigenesis. Biochim Biophys Acta 1602:97-113 (Pubitemid 34521790)
10. Kuehl DW, Serrano S, Naumann S (1994) Identification of potentially mutagenic contaminants in the aquatic environmental by liquid chromatographic-thermospray mass spectrometric characterization of in vitro DNA adducts. J Chrom 684:1113-1119
11. Lindahl T, Wood RD (1999) Quality control by DNA repair. Science 286:1897-1905 (Pubitemid 129515891)
12. Lundin C, North M, Erixon K, Walters K, Jenssen D, Goldman A S H, Helleday T (2005) Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA doublestrand breaks. Nucleic Acids Res 33:3799-3811 (Pubitemid 41418549)
13. Martinez GR, Loureiro AP, Marques SA, Miyamoto S, Yamaguchi LF, Onuki J et al (2003) Oxidative and alkylating damage in DNA. Mutat Res 544:115-127 (Pubitemid 37487655)
14. Miranda SR, Noguti J, Carvalho JG, Oshima CT, Ribeiro DA (2011) Oxidative DNA damage is a preliminary step during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. J Mol Histol 42:181-186
15. Nagpal JK, Patnaik S, Das BR (2002) Prevalence of high-risk human papilloma virus types and its association with P53 codon 72 polymorphism in tobacco addicted oral squamous cell carcinoma OSCC patients of Eastern India. Int J Cancer 10:649-653 (Pubitemid 34087805)
16. Ribeiro DA, Assis GF (2008) Expression of placental glutathione S-transferase in rat tongue mucosa exposed to cigarette smoke. J Mol Histol 39:115-119
17. Ribeiro DA, Favero Salvadori DM, Da Silva RN, Ribeiro Darros B, Alencar Marques ME (2004) Genomic instability in nonneoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oral Oncol 40:910-915 (Pubitemid 39369563)
18. Ribeiro DA, Salvadori DM, Marques ME (2005) Abnormal expression of bcl-2 and bax in rat tongue mucosa during the development of squamous cell carcinoma induced by 4-nitroquinoline 1-oxide. Int J Exp Pathol 86:375-381 (Pubitemid 41746376)
19. Ribeiro DA, Marques ME, Salvadori DM (2006) Antimicrobial endodontic compounds do not modulate alkylation-induced genotoxicity and oxidative stress in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e32-e36 (Pubitemid 44109984)
20. Ribeiro DA, Kitakawa D, Domingues MA, Cabral LA, Marques ME, Salvadori DM (2007a) Survivin and nitric oxide inducible synthase production during 4NQO-induced rat tongue carcinogenesis: a possible relationship. Exp Mol Pathol 83:131-137 (Pubitemid 46842970)
21. Ribeiro DA, Marques ME, Salvadori DM (2007b) Lack of effect of prior treatment with fluoride on genotoxicity of two chemical agents in vitro. Caries Res 41:239-243
22. Saran R, Tiwari RK, Reddy PP, Ahuja YR (2008) Risk assessment of oral cancer in patients with pre-cancerous states of the oral cavity using micronucleus test and challenge assay. Oral Oncol 44:354-360 (Pubitemid 351380980)
23. Sarasin A (2003) An overview of the mechanisms of mutagenesis and carcinogenesis. Mutat Res 544:99-106 (Pubitemid 37487653)
24. Sugimura T, Terada M, Yokota J, Hirohashi S, Wakabayashi K (1992) Multiple genetic alterations in human carcinogenesis. Environ Health Perspect 98:5-12 (Pubitemid 23061777)
25. Tanaka T, Kohno H, Sakata K, Yamada Y, Hirose Y, Sugie S, Mori H (2002) Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Carcinogenesis 23:1361-1367
26. Tice RR, Agurell E, Anderson D et al (2000) Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206-221 (Pubitemid 30196665)
27. Xi S, Grandis JR (2003) Gene therapy for the treatment of oral squamous cell carcinoma. J Dent Res 82:11-16