Allosteric inhibition of cobalt binding to albumin by fatty acids: Implications for the detection of myocardial ischemia

Journal of Medicinal Chemistry

Volumn 55, Issue 9, 2012, Pages 4425-4430

  Lu, Jin ^a,c   Stewart, Alan J ^b   Sadler, Peter J ^a   Pinheiro, Teresa J T ^a   Blindauer, Claudia A ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

^c Lonza Biologics Inc Portsmouth   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BOVINE SERUM ALBUMIN; COBALT; DITHIOTHREITOL; FATTY ACID; MYRISTIC ACID;

ABSORPTION; ALLOSTERISM; ARTICLE; CHEMICAL BINDING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HEART MUSCLE ISCHEMIA; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BIOLOGICAL MARKERS; CALORIMETRY; CATTLE; COBALT; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MYOCARDIAL ISCHEMIA; MYRISTIC ACID; SERUM ALBUMIN, BOVINE;

EID: 84861079557     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3003137     Document Type: Article

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