Fluorinated and pegylated polyaspartamide derivatives to increase solubility and efficacy of Flutamide

Journal of Drug Targeting

Volumn 20, Issue 5, 2012, Pages 433-444

  Piccionello, Antonio Palumbo ^a   Pitarresi, Giovanna ^a,b   Pace, Andrea ^a   Triolo, Daniela ^a   Picone, Pasquale ^b   Buscemi, Silvestre ^a   Giammona, Gaetano ^a,c  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR Consiglio Nazionale delle Ricerche   (Italy)

^c CNR   (Italy)

Author keywords

Cancer targeting; Cell model; Colloidal particles; Drug delivery; Polymer

Indexed keywords

3 CARBOXYETHYL 5 PENTADECAFLUOROHEPTYL 1,2,4 OXADIAZOLE; 5 PENTAFLUOROPHENYL 3 PERFLUOROHEPTYL 1,2,4 OXADIAZOLE; ALPHA,BETA POLY(N 2 HYDROXYETHYL)DEXTRO LEVO ASPARTAMIDE; COPOLYMER; FLUTAMIDE; MACROGOL; OXADIAZOLE DERIVATIVE; POLY[N (2 HYDROXYETHYL)ASPARTAMIDE]; UNCLASSIFIED DRUG;

ANALYSIS; ARTICLE; DRUG EFFICACY; DRUG SOLUBILITY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; LIGHT SCATTERING ANALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; PYRENE COLORIMETRIC ASSAY; SCANNING ELECTRON MICROSCOPY;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, GEL; DIHYDROTESTOSTERONE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ETHYLENEDIAMINES; FLUTAMIDE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; MICELLES; MICROSCOPY, ELECTRON, SCANNING; OXADIAZOLES; PEPTIDES; POLYETHYLENE GLYCOLS; POLYMERS; PROSTATIC NEOPLASMS; SOLUBILITY;

EID: 84861069152     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2012.680961     Document Type: Article

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