Posttransplant lymphoproliferative disorders

Advances in Hematology

Volumn 2012, Issue , 2012, Pages

  Ibrahim, Hazem A H ^a,b   Naresh, Kikkeri N ^a  

^a IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^b MANSOURA UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; OKT 3; TACROLIMUS;

B LYMPHOCYTE; CELL INTERACTION; DRUG DOSE REDUCTION; EPIGENETICS; EPSTEIN BARR VIRUS INFECTION; GENE MUTATION; HUMAN; IMMUNOSTIMULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; ONCOGENE; PATHOGENESIS; PLASMACYTOID DENDRITIC CELL; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; RISK FACTOR; TUMOR SUPPRESSOR GENE;

EID: 84861047389     PISSN: 16879104     EISSN: 16879112     Source Type: Journal    
DOI: 10.1155/2012/230173     Document Type: Review

References (88)

1. Kwong Y. L., Lam C. C. K., Chan T. M., Post-transplantation lymphoproliferative disease of natural killer cell lineage: a clinicopathological and molecular analysis British Journal of Haematology 2000 110 1 197 202 (Pubitemid 30625608)
2. Kumar S., Kumar D., Kingma D. W., Jaffe E. S., Epstein-Barr virus-associated T-cell lymphoma in a renal transplant patient American Journal of Surgical Pathology 1993 17 10 1046 1053 (Pubitemid 23289347)
3. Swerdlow S. H., Webber S. A., Chadburn A., Swerdlow S. H., Campo E., Harris N. L., Jaffe E. S., Pileri S. A., Stein H., Thiele J., Vardiman J. W., Post-transplant lymphoproliferative disorders WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008 Lyon, France IARC 343 349
4. Yin C. C., Medeiros L. J., Abruzzo L. V., Jones D., Farhood A. I., Thomazy V. A., EBV-associated B- and T-cell posttransplant lymphoproliferative disorders following primary EBV infection in a kidney transplant recipient American Journal of Clinical Pathology 2005 123 2 222 228 (Pubitemid 40194083)
5. Chadburn A., Suciu-Foca N., Cesarman E., Reed E., Michler R. E., Knowles D. R., Post-transplantation lymphoproliferative disorders arising in solid organ transplant recipients are usually of recipient origin American Journal of Pathology 1995 147 6 1862 1870
6. Zutter M. M., Martin P. J., Sale G. E., Shulman H. M., Fisher L., Thomas E. D., Durnam D. M., Epstein-Barr virus lymphoproliferation after bone marrow transplantation Blood 1988 72 2 520 529
7. Ghobrial I. M., Habermann T. M., Macon W. R., Ristow K. M., Larson T. S., Walker R. C., Ansell S. M., Gores G. J., Stegall M. D., McGregor C. G., Differences between early and late posttransplant lymphoproliferative disorders in solid organ transplant patients: are they two different diseases? Transplantation 2005 79 2 244 247
8. Choi J. H., Park B. B., Suh C., Won J. H., Lee W. S., Shin H. J., Clinical characteristics of monomorphic post-transplant lymphoproliferative disorders Journal of Korean Medical Science 2010 25 4 523 526
9. Dharnidharka V. R., Tejani A. H., Ho P. L., Harmon W. E., Post-transplant lymphoproliferative disorder in the United States: young Caucasian males are at highest risk American Journal of Transplantation 2002 2 10 993 998 (Pubitemid 36330232)
10. Dharnidharka R. Vikas, 2006, http://www.emedicine.com/ped/topic2851.htm
11. Cox K. L., Lawrence-Miyasaki L. S., Garcia-Kennedy R., Lennette E. T., Martinez O. M., Krams S. M., Berquist W. E., So S. K. S., Esquivel C. O., An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation Transplantation 1995 59 4 524 529
12. Allen U. D., Farkas G., Hébert D., Weitzman S., Stephens D., Petric M., Tellier R., Ngan B., Fecteau A., West L., Wasfy S., Risk factors for post-transplant lymphoproliferative disorder in pediatric patients: a case-control study Pediatric Transplantation 2005 9 4 450 455 (Pubitemid 41153264)
13. Katz B. Z., Pahl E., Crawford S. E., Kostyk M. C., Rodgers S., Seshadri R., Proytcheva M., Pophal S., Case-control study of risk factors for the development of post-transplant lymphoproliferative disease in a pediatric heart transplant cohort Pediatric Transplantation 2007 11 1 58 65 (Pubitemid 46100956)
14. Vakiani E., Nandula S. V., Subramaniyam S., Keller C. E., Alobeid B., Murty V. V., Bhagat G., Cytogenetic analysis of B-cell posttransplant lymphoproliferations validates the World Health Organization classification and suggests inclusion of florid follicular hyperplasia as a precursor lesion Human Pathology 2007 38 2 315 325 (Pubitemid 46096557)
15. Harris N. L., Ferry J. A., Swerdlow S. H., Posttransplant lymphoproliferative disorders: summary of Society for Hematopathology Workshop Seminars in Diagnostic Pathology 1997 14 8 14 (Pubitemid 27078881)
16. Knowles D. M., Cesarman E., Chadburn A., Frizzera G., Chen J., Rose E. A., Michler R. E., Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders Blood 1995 85 2 552 565
17. Chadburn A., Chen J. M., Hsu D. T., Frizzera G., Cesarman E., Garrett T. J., Mears J. G., Zangwill S. D., Addonizio L. J., Michler R. E., Knowles D. M., The morphologic and molecular genetic categories of posttransplantation lymphoproliferative disorders are clinically relevant Cancer 1998 82 10 1978 1987 (Pubitemid 28208656)
18. Tang M. B. Y., Tan E. S. T., Tan S. H., Late-onset Epstein-Barr virus-negative post-transplant lymphoproliferative disorder presenting as ulcerated necrotic papules and nodules in a renal transplant patient Australasian Journal of Dermatology 2008 49 2 100 102 (Pubitemid 351537563)
19. Djokic M., Le Beau M. M., Swinnen L. J., Smith S. M., Rubin C. M., Anastasi J., Carlson K. M., Post-transplant lymphoproliferative disorder subtypes correlate with different recurring chromosomal abnormalities Genes Chromosomes and Cancer 2006 45 3 313 318 (Pubitemid 43238481)
20. Vakiani E., Basso K., Klein U., Mansukhani M. M., Narayan G., Smith P. M., Murty V. V., Dalla-Favera R., Pasqualucci L., Bhagat G., Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology Hematological Oncology 2008 26 4 199 211
21. Borenstein J., Pezzella F., Gatter K. C., Plasmablastic lymphomas may occur as post-transplant lymphoproliferative disorders Histopathology 2007 51 6 774 777 (Pubitemid 350179408)
22. Naresh K. N., Lymphoproliferative disorders in the immunosuppressed Diagnostic Histopathology 2010 16 4 206 215
23. Hernandez C., Cetner A. S., Wiley E. L., Cutaneous presentation of plasmablastic post-transplant lymphoproliferative disorder in a 14-month-old Pediatric Dermatology 2009 26 6 713 716
24. Morovic A., Jaffe E. S., Raffeld M., Metachronous EBV-associated B-cell and T-cell posttransplant lymphoproliferative disorders in a heart transplant recipient American Journal of Surgical Pathology 2009 33 149 154
25. Esquiche Len J., Takahama Jnior A., Vassallo J., Soares F. A., De Almeida O. P., Ajudarte Lopes M., EBV-associated polymorphic posttransplant lymphoproliferative disorder presenting as gingival ulcers International Journal of Surgical Pathology 2011 19 2 241 246
26. Ibrahim H. A. H., Menasce L. P., Pomplun S., Burke M., Bower M., Naresh K. N., Presence of monoclonal T-cell populations in B-cell post-transplant lymphoproliferative disorders Modern Pathology 2011 24 232 240
27. Capello D., Rossi D., Gaidano G., Post-transplant lymphoproliferative disorders: molecular basis of disease histogenesis and pathogenesis Hematological Oncology 2005 23 2 61 67 (Pubitemid 41774988)
28. Kppers R., B cells under influence: transformation of B cells by Epstein-Barr virus Nature Reviews Immunology 2003 3 10 801 812
29. Rickinson A., Epstein-Barr virus Virus Research 2002 82 109 113 (Pubitemid 34273721)
30. Thorley-Lawson D. A., Epstein-Barr virus: exploiting the immune system Nature Reviews Immunology 2001 1 1 75 82 (Pubitemid 33741978)
31. Chen A., Zhao B., Kieff E., Aster J. C., Wang F., EBNA-3B- and EBNA-3C-regulated cellular genes in Epstein-Barr virus-immortalized lymphoblastoid cell lines Journal of Virology 2006 80 20 10139 10150 (Pubitemid 44522607)
32. Thorley-Lawson D. A., Epstein-Barr virus: exploiting the immune system Nature Reviews Immunology 2001 1 1 75 82 (Pubitemid 33741978)
33. Sbih-Lammali F., Djennaoui D., Belaoui H., Bouguermouh A., Decaussin G., Ooka T., Transcriptional expression of Epstein-Barr virus genes and proto-oncogenes in North African nasopharyngeal carcinoma Journal of Medical Virology 1996 49 1 7 14 (Pubitemid 26164932)
34. Hochberg D., Middeldorp J. M., Catalina M., Sullivan J. L., Luzuriaga K., Thorley-Lawson D. A., Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo Proceedings of the National Academy of Sciences of the United States of America 2004 101 1 239 244 (Pubitemid 38084234)
35. Capello D., Cerri M., Muti G., Berra E., Oreste P., Deambrogi C., Rossi D., Dotti G., Conconi A., Vigan M., Magrini U., Ippoliti G., Morra E., Gloghini A., Rambaldi A., Paulli M., Carbone A., Gaidano G., Molecular histogenesis of posttransplantation lymphoproliferative disorders Blood 2003 102 10 3775 3785 (Pubitemid 37409400)
36. Nelson B. P., Nalesnik M. A., Bahler D. W., Locker J., Fung J. J., Swerdlow S. H., Epstein-Barr virus-negative post-transplant lymphoproliferative disorders: a distinct entity? American Journal of Surgical Pathology 2000 24 3 375 385 (Pubitemid 30127473)
37. Johnson L. R., Nalesnik M. A., Swerdlow S. H., Impact of Epstein-Barr virus in monomorphic B-cell posttransplant lymphoproliferative disorders: a histogenetic study American Journal of Surgical Pathology 2006 30 12 1604 1612 (Pubitemid 44808798)
38. Gan Y. J., Razzouk B. I., Su T., Sixbey J. W., A defective, rearranged Epstein-Barr virus genome in EBER-negative and EBER-positive Hodgkin's disease American Journal of Pathology 2002 160 3 781 786 (Pubitemid 34224567)
39. Ambinder R. F., Gammaherpesviruses and 'hit-and-run' oncogenesis American Journal of Pathology 2000 156 1 1 3 (Pubitemid 30644430)
40. Birkeland S. A., Hamilton-Dutoit S., Is posttransplant lymphoproliferative disorder (PTLD) caused by any specific immunosuppressive drug or by the transplantation per se? Transplantation 2003 76 6 984 988 (Pubitemid 37186032)
41. Frank D., Cesarman E., Yi Fang Liu, Michler R. E., Knowles D. M., Posttransplantation lymphoproliferative disorders frequently contain type A and not type B Epstein-Barr virus Blood 1995 85 5 1396 1403
42. Ibrahim H. A. H., Menasce L. P., Pomplun S., Burke M., Bower M., Naresh K. N., Epstein-Barr virus (EBV) genotypes among human immunodeficiency virus (HIV)-related B-cell Lymphomas and B-cell post-transplant lymphoproliferative disorders (B-PTLD)-late-onset lymphomas, especially in the HIV setting, are associated with type-B-EBV European Journal of Haematology 2010 85 3 227 230
43. Kapelushnik J., Ariad S., Benharroch D., Landau D., Moser A., Delsol G., Brousset P., Post renal transplantation human herpesvirus 8-associated lymphoproliferative disorder and Kaposi's sarcoma British Journal of Haematology 2001 113 2 425 428 (Pubitemid 32523148)
44. Gaidano G., Carbone A., Primary effusion lymphoma: a liquid phase lymphoma of fluid-filled body cavities Advances in Cancer Research 2000 80 115 146 (Pubitemid 33717324)
45. Chen W., Huang Q., Zuppan C. W., Rowsell E. H., Cao J. D., Weiss L. M., Wang J., Complete absence of KSHV/HHV-8 in posttransplant lymphoproliferative disorders an immunohistochemical and molecular study of 52 cases American Journal of Clinical Pathology 2009 131 5 632 639
46. Duval A., Raphael M., Brennetot C., Poirel H., Buhard O., Aubry A., Martin A., Krimi A., Leblond V., Gabarre J., Davi F., Charlotte F., Berger F., Gaidano G., Capello D., Canioni D., Bordessoule D., Feuillard J., Gaulard P., Delfau M. H., Ferlicot S., Eclache V., Prevot S., Guettier C., Lefevre P. C., Adotti F., Hamelin R., The mutator pathway is a feature of immunodeficiency- related lymphomas Proceedings of the National Academy of Sciences of the United States of America 2004 101 14 5002 5007 (Pubitemid 38469192)
47. Capello D., Gaidano G., Post-transplant lymphoproliferative disorders: role of viral infection, genetic lesions and antigen stimulation in the pathogenesis of the disease Mediterranean Journal of Hematology and Infectious Diseases 2009 1, article e2009018 2
48. Baron B. W., Nucifora G., McCabe N., Espinosa R., Le Beau M. M., McKeithan T. W., Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas Proceedings of the National Academy of Sciences of the United States of America 1993 90 11 5262 5266 (Pubitemid 23183018)
49. Windebank K., Walwyn T., Kirk R., Parry G., Hasan A., Bown N., Wilkins B., Post cardiac transplantation lymphoproliferative disorder presenting as t(8;14) Burkitt leukaemia/lymphoma treated with low intensity chemotherapy and rituximab Pediatric Blood and Cancer 2009 53 3 392 396
50. Poirel H. A., Bernheim A., Schneider A., Meddeb M., Choquet S., Leblond V., Charlotte F., Davi F., Canioni D., Macintyre E., Mamzer-Bruneel M. F., Hirsch I., Hermine O., Martin A., Cornillet-Lefebvre P., Patey M., Toupance O., Kémény J. L., Deteix P., Raphal M., Characteristic pattern of chromosomal imbalances in posttransplantation lymphoproliferative disorders: correlation with histopathological subcategories and EBV status Transplantation 2005 80 2 176 184 (Pubitemid 41061673)
51. Cerri M., Capello D., Muti G., Rambaldi A., Paulli M., Gloghini A., Berra E., Deambrogi C., Rossi D., Franceschetti S., Conconi A., Morra E., Pasqualucci L., Carbone A., Gaidano G., Aberrant somatic hypermutation in post-transplant lymphoproliferative disorders British Journal of Haematology 2004 127 3 362 364 (Pubitemid 39468954)
52. Fasan O., Willmott C., Czepulkowski B., Baker A., Rees D., Salisbury J., Mufti G. J., Epstein-Barr virus-related post-transplant lymphoproliferative disorder with t(9;14)(p11 12;q32) Cancer Genetics and Cytogenetics 2003 142 2 134 136 (Pubitemid 36434134)
53. Rinaldi A., Kwee I., Poretti G., Mensah A., Pruneri G., Capello D., Rossi D., Zucca E., Ponzoni M., Catapano C., Tibiletti M. G., Paulli M., Gaidano G., Bertoni F., Comparative genome-wide profiling of post-transplant lymphoproliferative disorders and diffuse large B-cell lymphomas British Journal of Haematology 2006 134 1 27 36 (Pubitemid 43830024)
54. Capello D., Rossi D., Gaidano G., Post-transplant lymphoproliferative disorders: molecular basis of disease histogenesis and pathogenesis Hematological Oncology 2005 23 2 61 67 (Pubitemid 41774988)
55. Rinaldi A., Capello D., Scandurra M., Greiner T. C., Chan W. C., Bhagat G., Rossi D., Morra E., Paulli M., Rambaldi A., Rancoita P. M. V., Inghirami G., Ponzoni M., Moreno S. M., Piris M. A., Mian M., Chigrinova E., Zucca E., Favera R. D., Gaidano G., Kwee I., Bertoni F., Single nucleotide polymorphism-arrays provide new insights in the pathogenesis of post-transplant diffuse large B-cell lymphoma British Journal of Haematology 2010 149 4 569 577
56. Ferreira B. I., Garca J. F., Suela J., Mollejo M., Camacho F. I., Carro A., Montes S., Piris M. A., Cigudosa J. C., Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasia Haematologica 2008 93 5 670 679 (Pubitemid 351669306)
57. Capello D., Scandurra M., Poretti G., Rancoita P. M. V., Mian M., Gloghini A., Deambrogi C., Martini M., Rossi D., Greiner T. C., Chan W. C., Ponzoni M., Moreno S. M., Piris M. A., Canzonieri V., Spina M., Tirelli U., Inghirami G., Rinaldi A., Zucca E., Favera R. D., Cavalli F., Larocca L. M., Kwee I., Carbone A., Gaidano G., Bertoni F., Genome wide DNA-profiling of HIV-related B-cell lymphomas British Journal of Haematology 2010 148 2 245 255
58. Lenz G., Wright G. W., Emre N. C. T., Kohlhammer H., Dave S. S., Davis R. E., Carty S., Lam L. T., Shaffer A. L., Xiao W., Powell J., Rosenwald A., Ott G., Muller-Hermelink H. K., Gascoyne R. D., Connors J. M., Campo E., Jaffe E. S., Delabie J., Smeland E. B., Rimsza L. M., Fisher R. I., Weisenburger D. D., Chan W. C., Staudt L. M., Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways Proceedings of the National Academy of Sciences of the United States of America 2008 105 36 13520 13525
59. Compagno M., Lim W. K., Grunn A., Nandula S. V., Brahmachary M., Shen Q., Bertoni F., Ponzoni M., Scandurra M., Califano A., Bhagat G., Chadburn A., Dalla-Favera R., Pasqualucci L., Mutations of multiple genes cause deregulation of NF-B in diffuse large B-cell lymphoma Nature 2009 459 7247 717 721
60. Craig F. E., Johnson L. R., Harvey S. A. K., Nalesnik M. A., Luo J. H., Bhattacharya S. D., Swerdlow S. H., Gene expression profiling of epstein-barr virus-positive and-negative monomorphic B-cell posttransplant lymphoproliferative disorders Diagnostic Molecular Pathology 2007 16 3 158 168 (Pubitemid 47329876)
61. Freudenreich C. H., Chromosome fragility: molecular mechanisms and cellular consequences Frontiers in Bioscience 2007 12 4911 4924
62. Das P. M., Singal R., DNA methylation and cancer Journal of Clinical Oncology 2004 22 22 4632 4642 (Pubitemid 41185132)
63. Rossi D., Gaidano G., Gloghini A., Deambrogi C., Franceschetti S., Berra E., Cerri M., Vendramin C., Conconi A., Viglio A., Muti G., Oreste P., Morra E., Paulli M., Capello D., Carbone A., Frequent aberrant promoter hypermethylation of O6-methylguanine- DNA methyltransferase and death-associated protein kinase genes in immunodeficiency-related lymphomas British Journal of Haematology 2003 123 3 475 478 (Pubitemid 37363490)
64. Bialik S., Kimchi A., DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death Seminars in Cancer Biology 2004 14 4 283 294 (Pubitemid 38824589)
65. Capello D., Berra E., Cerri M., Gaidano G., Post-transplant lymphoproliferative disorders: molecular analysis of histogenesis and pathogenesis Minerva Medica 2004 95 1 53 64 (Pubitemid 38667804)
66. Martin A., Baran-Marzak F., El Mansouri S., Legendre C., Leblond V., Charlotte F., Davi F., Canioni D., Raphael M., Expression of p16/INK4a in posttransplantation lymphoproliferative disorders American Journal of Pathology 2000 156 5 1573 1579 (Pubitemid 30646697)
67. Arbiser J. L., Mann K. P., Losken E. M., Cohen C., Reddy K., Kokko K., Pollack B., Fan C. Y., O'Reilly F., Presence of p16 hypermethylation and Epstein-Barr virus infection in transplant-associated hematolymphoid neoplasm of the skin Journal of the American Academy of Dermatology 2006 55 5 794 798 (Pubitemid 44556844)
68. Cyster J. G., Goodnow C. C., Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection Immunity 1995 2 1 13 24
69. Cerri M., Deambrogi C., Rossi D., Lunghi M., Zigrossi P., Spina V., De Paoli L., Riccomagno P., Gloghini A., Lucioni M., Capello D., Paulli M., Carbone A., Gaidano G., Aberrant methylation of SHP-1 (SH2-containing phosphatase 1) and SOCS-1 (suppressor of cytokine signaling 1) genes in immunodeficiency- related lymphomas 92, supplement 2, abstract 0289 Proceedings of the 12th Congress of the European Hematology Association June 2007 105 Haematologica
70. Barchet W., Cella M., Colonna M., Plasmacytoid dendritic cellsvirus experts of innate immunity Seminars in Immunology 2005 17 4 253 261 (Pubitemid 40981931)
71. Lim W. H., Kireta S., Thomson A. W., Russ G. R., Coates P. T. H., Renal transplantation reverses functional deficiencies in circulating dendritic cell subsets in chronic renal failure patients Transplantation 2006 81 2 160 168
72. Hackstein H., Renner F. C., Bohnert A., Nockher A., Frommer T., Bein G., Weimer R., Dendritic cell deficiency in the blood of kidney transplant patients on long-term immunosuppression: results of a prospective matched-cohort study American Journal of Transplantation 2005 5 12 2945 2953 (Pubitemid 43923956)
73. Gary-Gouy H., Lebon P., Dalloul A. H., Type I interferon production by plasmacytoid dendritic cells and monocytes is triggered by viruses, but the level of production is controlled by distinct cytokines Journal of Interferon and Cytokine Research 2002 22 6 653 659 (Pubitemid 35034523)
74. Salek-Ardakani S., Arrand J. R., Mackett M., Epstein-Barr virus encoded interleukin-10 inhibits HLA-class I, ICAM-1, and B7 expression on human monocytes: implications for immune evasion by EBV Virology 2002 304 2 342 351 (Pubitemid 36069174)
75. Mocellin S., Panelli M. C., Wang E., Nagorsen D., Marincola F. M., The dual role of IL-10 Trends in Immunology 2003 24 1 36 43 (Pubitemid 35462111)
76. Jegalian A. G., Facchetti F., Jaffe E. S., Plasmacytoid dendritic cells physiologic roles and pathologic states Advances in Anatomic Pathology 2009 16 6 392 404
77. Kutzner H., Kerl H., Pfaltz M. C., Kempf W., CD123-positive plasmacytoid dendritic cells in primary cutaneous marginal zone b-cell lymphoma: diagnostic and pathogenetic implications American Journal of Surgical Pathology 2009 33 9 1307 1313
78. Ibrahim H. A. H., Menasce L., Pomplun S., Burke M., Bower M., Naresh K. N., Tumour infiltrating plasmacytoid dendritic cells in B cell post-transplant lymphoproliferative disorders, human immunodeficiency virus-associated B cell lymphomas and immune competent diffuse large B cell lymphomas Histopathology 2011 59 1 152 156
79. Xystrakis E., Dejean A. S., Bernard I., Druet P., Liblau R., Gonzalez-Dunia D., Saoudi A., Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation Blood 2004 104 10 3294 3301 (Pubitemid 39507148)
80. Thornton A. M., Shevach E. M., CD4 + CD25 + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production Journal of Experimental Medicine 1998 188 2 287 296 (Pubitemid 28357757)
81. Piccirillo C. A., Shevach E. M., Cutting edge: control of CD8 + T cell activation by CD4 + CD25 + immunoregulatory cells Journal of Immunology 2001 167 3 1137 1140 (Pubitemid 32703105)
82. Chaperot L., Manches O., Mi J. Q., Moine A., Jacob M. C., Gressin R., Molens J. P., Sotto J. J., Leroux D., Bensa J. C., Plumas J., Differentiation of anti-tumour cytotoxic T lymphocytes from autologous peripheral blood lymphocytes in non-Hodgkin's lymphomas British Journal of Haematology 2002 119 2 425 431 (Pubitemid 35365494)
83. Lim H. W., Hillsamer P., Banham A. H., Kim C. H., Cutting edge: direct suppression of B cells by CD4 + CD25 + regulatory T cells Journal of Immunology 2005 175 7 4180 4183 (Pubitemid 41361949)
84. Curiel T. J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., Evdemon-Hogan M., Conejo-Garcia J. R., Zhang L., Burow M., Zhu Y., Wei S., Kryczek I., Daniel B., Gordon A., Myers L., Lackner A., Disis M. L., Knutson K. L., Chen L., Zou W., Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival Nature Medicine 2004 10 9 942 949 (Pubitemid 39273735)
85. Carreras J., Lopez-Guillermo A., Fox B. C., Colomo L., Martinez A., Roncador G., Montserrat E., Campo E., Banham A. H., High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma Blood 2006 108 9 2957 2964
86. Yang Z. Z., Novak A. J., Stenson M. J., Witzig T. E., Ansell S. M., Intratumoral CD4 + CD25 + regulatory T-cell-mediated suppression of infiltrating CD4 + T cells in B-cell non-Hodgkin lymphoma Blood 2006 107 9 3639 3646
87. Verdonk R. C., Haagsma E. B., Jonker M. R., Bok L. I. H., Zandvoort J. H., Kleibeuker J. H., Faber K. N., Dijkstra G., Effects of different immunosuppressive regimens on regulatory T-cells in noninflamed colon of liver transplant recipients Inflammatory Bowel Diseases 2007 13 6 703 709 (Pubitemid 46909984)
88. Richendollar B. G., Tsao R. E., Elson P., Jin T., Steinle R., Pohlman B., Hsi E. D., Predictors of outcome in post-transplant lymphoproliferative disorder: an evaluation of tumor infiltrating lymphocytes in the context of clinical factors Leukemia and Lymphoma 2009 50 12 2005 2012