Knockdown of BDNF suppressed invasion of HepG2 and HCCLM3 cells, a mechanism associated with inactivation of RhoA or Rac1 and actin skeleton disorganization

APMIS

Volumn 120, Issue 6, 2012, Pages 469-476

  Guo, Dawei ^a   Sun, Wenyu ^a   Zhu, Lei ^a   Zhang, Hongbin ^a   Hou, Xuezhong ^b   Liang, Jian ^a   Jiang, Xiaofeng ^a   Liu, Chen ^c  

^a CHINA MEDICAL UNIVERSITY   (China)

^b The Chinese People's Liberation Army 463th hospital   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Actin cytoskeleton; BDNF; Hepatocellular carcinoma; Invasion; Rho GTPase; TrkB

Indexed keywords

BETA ACTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; FLUORESCEIN ISOTHIOCYANATE; PHALLOIDIN; PROTEIN CDC42; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA;

ACTIN FILAMENT; ACTIN POLYMERIZATION; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL INVASION; CELL STRAIN; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; WESTERN BLOTTING;

ACTINS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARCINOMA, HEPATOCELLULAR; CDC42 GTP-BINDING PROTEIN; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; NEOPLASM INVASIVENESS; RAC1 GTP-BINDING PROTEIN; RECEPTOR, TRKB; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84860995168     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2011.02855.x     Document Type: Article

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