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Volumn 10, Issue , 2010, Pages

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; FOCAL ADHESION KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; DDEF2 PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;

EID: 77649088952     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-43     Document Type: Article
Times cited : (37)

References (34)
  • 2
    • 0037430992 scopus 로고    scopus 로고
    • Cisplatin-induced cytotoxicity is blocked by brain-derived neurotrophic factor activation of TrkB signal transduction path in neuroblastoma
    • 10.1016/S0304-3835(02)00723-1, 12691830
    • Jaboin J, Hong A, Kim CJ, Thiele CJ. Cisplatin-induced cytotoxicity is blocked by brain-derived neurotrophic factor activation of TrkB signal transduction path in neuroblastoma. Cancer Lett 2003, 193:109-14. 10.1016/S0304-3835(02)00723-1, 12691830.
    • (2003) Cancer Lett , vol.193 , pp. 109-114
    • Jaboin, J.1    Hong, A.2    Kim, C.J.3    Thiele, C.J.4
  • 3
    • 27944460443 scopus 로고    scopus 로고
    • The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness
    • 10.1093/carcin/bgi192, 16051641
    • Hecht M, Schulte JH, Eggert A, Wilting J, Schweigerer L. The neurotrophin receptor TrkB cooperates with c-Met in enhancing neuroblastoma invasiveness. Carcinogenesis 2005, 26:2105-2115. 10.1093/carcin/bgi192, 16051641.
    • (2005) Carcinogenesis , vol.26 , pp. 2105-2115
    • Hecht, M.1    Schulte, J.H.2    Eggert, A.3    Wilting, J.4    Schweigerer, L.5
  • 4
    • 0028948182 scopus 로고
    • Expression of brain-derived neurotrophic factor and pl4STrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells
    • Matsumoto K, Wada RK, Yamashiro JM, Kaplan DR, Thiele CJ. Expression of brain-derived neurotrophic factor and pl4STrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. Cancer Res 1995, 55:1798-1806.
    • (1995) Cancer Res , vol.55 , pp. 1798-1806
    • Matsumoto, K.1    Wada, R.K.2    Yamashiro, J.M.3    Kaplan, D.R.4    Thiele, C.J.5
  • 5
    • 38949109297 scopus 로고    scopus 로고
    • Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer
    • 10.1111/j.1349-7006.2007.00722.x, 18201274
    • Yu X, Liu L, Cai B, He Y, Wan X. Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer. Cancer Sci 2008, 99:543-52. 10.1111/j.1349-7006.2007.00722.x, 18201274.
    • (2008) Cancer Sci , vol.99 , pp. 543-552
    • Yu, X.1    Liu, L.2    Cai, B.3    He, Y.4    Wan, X.5
  • 8
    • 4344627055 scopus 로고    scopus 로고
    • Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
    • 10.1038/nature02765, 15329723
    • Douma S, Van Laar T, Zevenhoven J, Meuwissen R, Van Garderen E, Peeper DS. Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 2004, 430:1034-9. 10.1038/nature02765, 15329723.
    • (2004) Nature , vol.430 , pp. 1034-1039
    • Douma, S.1    Van Laar, T.2    Zevenhoven, J.3    Meuwissen, R.4    Van Garderen, E.5    Peeper, D.S.6
  • 9
    • 0037112455 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3-kinase pathway
    • Jaboin J, Kim CJ, Kaplan DR, Thiele CJ. Brain-derived neurotrophic factor activation of TrkB protects neuroblastoma cells from chemotherapy-induced apoptosis via phosphatidylinositol 3-kinase pathway. Cancer Res 2002, 62:6756-6763.
    • (2002) Cancer Res , vol.62 , pp. 6756-6763
    • Jaboin, J.1    Kim, C.J.2    Kaplan, D.R.3    Thiele, C.J.4
  • 10
    • 16844374910 scopus 로고    scopus 로고
    • Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death
    • 10.1158/0008-5472.CAN-04-3606, 15781614
    • Li Z, Jaboin J, Dennis PA, Thiele CJ. Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death. Cancer Res 2005, 65:2070-5. 10.1158/0008-5472.CAN-04-3606, 15781614.
    • (2005) Cancer Res , vol.65 , pp. 2070-2075
    • Li, Z.1    Jaboin, J.2    Dennis, P.A.3    Thiele, C.J.4
  • 11
    • 37349096959 scopus 로고    scopus 로고
    • Targeting Akt to increase the sensitivity of neuroblastoma to chemotherapy:lessons learned from the brain-derived neurotrophic factor/TrkB signal transduction pathway
    • 10.1517/14728222.11.12.1611, 18020981
    • Li Z, Thiele CJ. Targeting Akt to increase the sensitivity of neuroblastoma to chemotherapy:lessons learned from the brain-derived neurotrophic factor/TrkB signal transduction pathway. Expert Opin Ther Targets 2007, 11:1611-21. 10.1517/14728222.11.12.1611, 18020981.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1611-1621
    • Li, Z.1    Thiele, C.J.2
  • 12
    • 34247203153 scopus 로고    scopus 로고
    • The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes
    • 10.1038/sj.jid.5700662, 17205062
    • Schindler EM, Baumgartner M, Gribben EM, Li L, Efimova T. The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes. J Invest Dermatol 2007, 127:1094-106. 10.1038/sj.jid.5700662, 17205062.
    • (2007) J Invest Dermatol , vol.127 , pp. 1094-1106
    • Schindler, E.M.1    Baumgartner, M.2    Gribben, E.M.3    Li, L.4    Efimova, T.5
  • 13
    • 0037081867 scopus 로고    scopus 로고
    • Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells
    • 10.1016/S0303-7207(01)00667-0, 11850124
    • Picascia A, Stanzione R, Chieffi P, Kisslinger A, Dikic I, Tramontano D. Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells. Mol Cell Endocrinol 2002, 186:81-7. 10.1016/S0303-7207(01)00667-0, 11850124.
    • (2002) Mol Cell Endocrinol , vol.186 , pp. 81-87
    • Picascia, A.1    Stanzione, R.2    Chieffi, P.3    Kisslinger, A.4    Dikic, I.5    Tramontano, D.6
  • 14
    • 3042683296 scopus 로고    scopus 로고
    • Differential regulation of cell migration and proliferation through proline-rich tyrosine kinase 2 in endothelial cells
    • 10.1210/en.2003-1433, 15070849
    • Kuwabara K, Nakaoka T, Sato K, Nishishita T, Sasaki T, Yamashita N. Differential regulation of cell migration and proliferation through proline-rich tyrosine kinase 2 in endothelial cells. Endocrinology 2004, 145:3324-30. 10.1210/en.2003-1433, 15070849.
    • (2004) Endocrinology , vol.145 , pp. 3324-3330
    • Kuwabara, K.1    Nakaoka, T.2    Sato, K.3    Nishishita, T.4    Sasaki, T.5    Yamashita, N.6
  • 16
    • 0034995547 scopus 로고    scopus 로고
    • A role for PYK2 in regulation of ERK1/2 MAP kinases and PI3-kinase by ANG II in vascular smooth muscle
    • Rocic P, Govindarajan G, Sabri A, Lucchesi PA. A role for PYK2 in regulation of ERK1/2 MAP kinases and PI3-kinase by ANG II in vascular smooth muscle. Am J Physiol Cell Physiol 2001, 280:C90-9.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Rocic, P.1    Govindarajan, G.2    Sabri, A.3    Lucchesi, P.A.4
  • 17
    • 10944223361 scopus 로고    scopus 로고
    • Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis
    • 10.1038/sj.onc.1208091, 15489898
    • Wei L, Yang Y, Zhang X, Yu Q. Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene 2004, 23:9052-61. 10.1038/sj.onc.1208091, 15489898.
    • (2004) Oncogene , vol.23 , pp. 9052-9061
    • Wei, L.1    Yang, Y.2    Zhang, X.3    Yu, Q.4
  • 18
    • 33845687683 scopus 로고    scopus 로고
    • RAFTK/PYK2 regulates EGF-induced PC12 cell spreading and movement
    • 10.1016/j.cellsig.2006.07.005, 16945503
    • Park SY, Li H, Avraham S. RAFTK/PYK2 regulates EGF-induced PC12 cell spreading and movement. Cell Signal 2007, 19:289-300. 10.1016/j.cellsig.2006.07.005, 16945503.
    • (2007) Cell Signal , vol.19 , pp. 289-300
    • Park, S.Y.1    Li, H.2    Avraham, S.3
  • 19
    • 0034594914 scopus 로고    scopus 로고
    • RAFTK/PYK2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion
    • 10.1038/sj.onc.1203422, 10713673
    • Zrihan-Licht S, Fu Y, Settleman J, Schinkmann K, Shaw L, Keydar I, Avraham S, Avraham H. RAFTK/PYK2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion. Oncogene 2000, 19:1318-28. 10.1038/sj.onc.1203422, 10713673.
    • (2000) Oncogene , vol.19 , pp. 1318-1328
    • Zrihan-Licht, S.1    Fu, Y.2    Settleman, J.3    Schinkmann, K.4    Shaw, L.5    Keydar, I.6    Avraham, S.7    Avraham, H.8
  • 20
    • 56949090552 scopus 로고    scopus 로고
    • Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer
    • 10.1016/j.lungcan.2008.05.008, 18571765
    • Zhang S, Qiu X, Gu Y, Wang E. Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer. Lung Cancer 2008, 62:295-301. 10.1016/j.lungcan.2008.05.008, 18571765.
    • (2008) Lung Cancer , vol.62 , pp. 295-301
    • Zhang, S.1    Qiu, X.2    Gu, Y.3    Wang, E.4
  • 21
    • 34447123807 scopus 로고    scopus 로고
    • Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis
    • 10.1158/0008-5472.CAN-07-0121, 17616679
    • Geiger TR, Peeper DS. Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis. Cancer Res 2007, 67:6221-9. 10.1158/0008-5472.CAN-07-0121, 17616679.
    • (2007) Cancer Res , vol.67 , pp. 6221-6229
    • Geiger, T.R.1    Peeper, D.S.2
  • 22
    • 0032589782 scopus 로고    scopus 로고
    • Role of neurotrophins and neurotrophins receptors in the in vitro invasion and heparanase production of human prostate cancer cells
    • 10.1023/A:1006652605568, 10545017
    • Walch ET, Marchetti D. Role of neurotrophins and neurotrophins receptors in the in vitro invasion and heparanase production of human prostate cancer cells. Clin Exp Metastasis 1999, 17:307-14. 10.1023/A:1006652605568, 10545017.
    • (1999) Clin Exp Metastasis , vol.17 , pp. 307-314
    • Walch, E.T.1    Marchetti, D.2
  • 23
    • 20344393365 scopus 로고    scopus 로고
    • The tyrosine kinase PYK2 promotes migration and invasion of glioma cells
    • 10.1593/neo.04712, 1501165, 15967096
    • Lipinski CA, Tran NL, Menashi E, Rohl C, Kloss J, Bay RC, Berens ME, Loftus JC. The tyrosine kinase PYK2 promotes migration and invasion of glioma cells. Neoplasia 2005, 7:435-45. 10.1593/neo.04712, 1501165, 15967096.
    • (2005) Neoplasia , vol.7 , pp. 435-445
    • Lipinski, C.A.1    Tran, N.L.2    Menashi, E.3    Rohl, C.4    Kloss, J.5    Bay, R.C.6    Berens, M.E.7    Loftus, J.C.8
  • 24
    • 63949084308 scopus 로고    scopus 로고
    • Up-regulation of Tropomyosin related kinase B contributes to resistance to detachment-induced apoptosis in hepatoma multicellular aggregations
    • 10.1007/s11033-008-9299-z, 18595003
    • Zhang Z, Han L, Liu Y, Liang X, Sun W. Up-regulation of Tropomyosin related kinase B contributes to resistance to detachment-induced apoptosis in hepatoma multicellular aggregations. Mol Biol Rep 2009, 36:1211-6. 10.1007/s11033-008-9299-z, 18595003.
    • (2009) Mol Biol Rep , vol.36 , pp. 1211-1216
    • Zhang, Z.1    Han, L.2    Liu, Y.3    Liang, X.4    Sun, W.5
  • 25
    • 0032939723 scopus 로고    scopus 로고
    • Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: expression patterns and effects on in vitro invasive behavior
    • 10.1002/(SICI)1097-0215(19990505)81:3<417::AID-IJC16>3.0.CO;2-6, 10209957
    • Miknyoczki SJ, Lang D, Huang L, Klein-Szanto AJ, Dionne CA, Ruggeri BA. Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: expression patterns and effects on in vitro invasive behavior. Int J Cancer 1999, 81:417-427. 10.1002/(SICI)1097-0215(19990505)81:3<417::AID-IJC16>3.0.CO;2-6, 10209957.
    • (1999) Int J Cancer , vol.81 , pp. 417-427
    • Miknyoczki, S.J.1    Lang, D.2    Huang, L.3    Klein-Szanto, A.J.4    Dionne, C.A.5    Ruggeri, B.A.6
  • 26
    • 0035253655 scopus 로고    scopus 로고
    • Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor
    • Eggert A, Grotzer MA, Ikegaki N, Zhao H, Cnaan A, Brodeur GM, Evans AE. Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor. J Clin Oncol 2001, 19:689-896.
    • (2001) J Clin Oncol , vol.19 , pp. 689-896
    • Eggert, A.1    Grotzer, M.A.2    Ikegaki, N.3    Zhao, H.4    Cnaan, A.5    Brodeur, G.M.6    Evans, A.E.7
  • 27
    • 0037339606 scopus 로고    scopus 로고
    • Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma
    • 10.1007/BF02706217, 12711810
    • Wadhwa S, Nag TC, Jindal A, Kushwaha R, Mahapatra AK, Sarkar C. Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma. J Biosci 2003, 28:181-8. 10.1007/BF02706217, 12711810.
    • (2003) J Biosci , vol.28 , pp. 181-188
    • Wadhwa, S.1    Nag, T.C.2    Jindal, A.3    Kushwaha, R.4    Mahapatra, A.K.5    Sarkar, C.6
  • 28
    • 0038033715 scopus 로고    scopus 로고
    • Growth, survival and migration: the Trk to cancer
    • full_text, 12613191
    • Rubin JB, Segal RA. Growth, survival and migration: the Trk to cancer. Cancer Treat Res 2003, 115:1-18. full_text, 12613191.
    • (2003) Cancer Treat Res , vol.115 , pp. 1-18
    • Rubin, J.B.1    Segal, R.A.2
  • 29
    • 19344367302 scopus 로고    scopus 로고
    • A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival
    • 10.1182/blood-2004-08-3096, 15657181
    • Pearse RN, Swendeman SL, Li Y, Rafii D, Hempstead BL. A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival. Blood 2005, 105:4429-36. 10.1182/blood-2004-08-3096, 15657181.
    • (2005) Blood , vol.105 , pp. 4429-4436
    • Pearse, R.N.1    Swendeman, S.L.2    Li, Y.3    Rafii, D.4    Hempstead, B.L.5
  • 30
    • 34250378582 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro
    • Festuccia C, Muzi P, Gravina GL, Millimaggi D, Speca S, Dolo V, Ricevuto E, Vicentini C, Bologna M. Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro. Int J Oncol 2007, 30:193-200.
    • (2007) Int J Oncol , vol.30 , pp. 193-200
    • Festuccia, C.1    Muzi, P.2    Gravina, G.L.3    Millimaggi, D.4    Speca, S.5    Dolo, V.6    Ricevuto, E.7    Vicentini, C.8    Bologna, M.9
  • 31
    • 56049123161 scopus 로고    scopus 로고
    • Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation
    • 10.1093/carcin/bgn203, 18765415
    • Sun CK, Man K, Ng KT, Ho JW, Lim ZX, Cheng Q, Lo CM, Poon RT, Fan ST. Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation. Carcinogenesis 2008, 29:2096-105. 10.1093/carcin/bgn203, 18765415.
    • (2008) Carcinogenesis , vol.29 , pp. 2096-2105
    • Sun, C.K.1    Man, K.2    Ng, K.T.3    Ho, J.W.4    Lim, Z.X.5    Cheng, Q.6    Lo, C.M.7    Poon, R.T.8    Fan, S.T.9
  • 32
    • 1442278553 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2
    • 10.1038/sj.onc.1207243, 14676843
    • McMullen M, Keller R, Sussman M, Pumiglia K. Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2. Oncogene 2004, 23:1275-82. 10.1038/sj.onc.1207243, 14676843.
    • (2004) Oncogene , vol.23 , pp. 1275-1282
    • McMullen, M.1    Keller, R.2    Sussman, M.3    Pumiglia, K.4
  • 33
    • 4043054389 scopus 로고    scopus 로고
    • RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner
    • 10.1074/jbc.M313527200, 15166227
    • Park SY, Avraham HK, Avraham S. RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. J Biol Chem 2004, 279:33315-22. 10.1074/jbc.M313527200, 15166227.
    • (2004) J Biol Chem , vol.279 , pp. 33315-33322
    • Park, S.Y.1    Avraham, H.K.2    Avraham, S.3
  • 34
    • 21744450576 scopus 로고    scopus 로고
    • Role of the actin cytoskeleton in G-protein-coupled receptor activation of PYK2 and paxillin in vascular smooth muscle
    • 10.1161/01.HYP.0000167990.82235.3c, 15911746
    • Ohanian V, Gatfield K, Ohanian J. Role of the actin cytoskeleton in G-protein-coupled receptor activation of PYK2 and paxillin in vascular smooth muscle. Hypertension 2005, 46:93-9. 10.1161/01.HYP.0000167990.82235.3c, 15911746.
    • (2005) Hypertension , vol.46 , pp. 93-99
    • Ohanian, V.1    Gatfield, K.2    Ohanian, J.3


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