Native analysis of plasma-derived clotting factor VIII concentrates: "Sponge effect" and contaminants

Electrophoresis

Volumn 33, Issue 8, 2012, Pages 1292-1298

  Blasi, Barbara ^a   D'Amici, Gian Maria ^a   D'Alessandro, Angelo ^a   Zolla, Lello ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Beriate; Clotting factor VIII; Emoclot; Factor VIII; Native complexes; Plasma derived

Indexed keywords

PROTEINS;

BERIATE; CLOTTING FACTOR VIII; EMOCLOT; FACTOR VIII; GEL-BASED; MANUFACTURING PROCESS; NATIVE COMPLEX; PLASMA-DERIVED; PROTEIN COMPLEXES;

FACTOR ANALYSIS;

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 1 MICROGLOBULIN; ALPHA 2 MACROGLOBULIN; APOLIPOPROTEIN A1; BLOOD CLOTTING FACTOR 8 CONCENTRATE; CERULOPLASMIN; COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C5; EMOCLOT; FIBRINOGEN; FIBRINOGEN ALPHA; FIBRINOGEN BETA; FIBRINOGEN GAMMA; GALECTIN 3; HAPTOGLOBIN; HEAT SHOCK PROTEIN 90 BETA; HEMOPEXIN; IMMUNOGLOBULIN HEAVY CHAIN; INTER ALPHA TRYPSIN HEAVY CHAIN ITIH1; KININOGEN I; LIPOPROTEIN GLN 1; PLATELET GLYCOPROTEIN 1B ALPHA; PROAPOLIPOPROTEIN; PROTHROMBIN; SERUM ALBUMIN; TRANSFERRIN; UNCLASSIFIED DRUG; VITRONECTIN; VON WILLEBRAND FACTOR;

ARTICLE; BLOOD CLOTTING; CHROMATOGRAPHY; CONTAMINATION; CONTROLLED STUDY; CRYOPRECIPITATION; ELECTROPHORESIS; IMMUNITY; INFLAMMATION; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PHYSICAL PHENOMENA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SPONGE EFFECT;

EID: 84860994971     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201100702     Document Type: Article

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