-
1
-
-
17644361955
-
The NOD mouse: a model of immune dysregulation
-
Anderson MS, Bluestone JA, (2005) The NOD mouse: a model of immune dysregulation. Annu Rev Immunol 23: 447-485.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 447-485
-
-
Anderson, M.S.1
Bluestone, J.A.2
-
2
-
-
23844525846
-
A comprehensive review of interventions in the NOD mouse and implications for translation
-
Shoda LK, Young DL, Ramanujan S, Whiting CC, Atkinson MA, et al. (2005) A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity 23: 115-126.
-
(2005)
Immunity
, vol.23
, pp. 115-126
-
-
Shoda, L.K.1
Young, D.L.2
Ramanujan, S.3
Whiting, C.C.4
Atkinson, M.A.5
-
3
-
-
33747598510
-
Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes
-
Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, et al. (2006) Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes. Proc Natl Acad Sci U S A 103: 12475-12480.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12475-12480
-
-
Chaparro, R.J.1
Konigshofer, Y.2
Beilhack, G.F.3
Shizuru, J.A.4
McDevitt, H.O.5
-
4
-
-
55849136929
-
Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice
-
Koulmanda M, Bhasin M, Hoffman L, Fan Z, Qipo A, et al. (2008) Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A 105: 16242-16247.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16242-16247
-
-
Koulmanda, M.1
Bhasin, M.2
Hoffman, L.3
Fan, Z.4
Qipo, A.5
-
5
-
-
34548751075
-
Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts
-
Koulmanda M, Budo E, Bonner-Weir S, Qipo A, Putheti P, et al. (2007) Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A 104: 13074-13079.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13074-13079
-
-
Koulmanda, M.1
Budo, E.2
Bonner-Weir, S.3
Qipo, A.4
Putheti, P.5
-
6
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone JA, Barriot S, Megret J, Bach JF, et al. (2003) TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 9: 1202-1208.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
-
7
-
-
33646392755
-
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs
-
Bresson D, Togher L, Rodrigo E, Chen Y, Bluestone JA, et al. (2006) Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs. J Clin Invest 116: 1371-1381.
-
(2006)
J Clin Invest
, vol.116
, pp. 1371-1381
-
-
Bresson, D.1
Togher, L.2
Rodrigo, E.3
Chen, Y.4
Bluestone, J.A.5
-
8
-
-
3042737844
-
Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4
-
Ogawa N, List JF, Habener JF, Maki T, (2004) Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes 53: 1700-1705.
-
(2004)
Diabetes
, vol.53
, pp. 1700-1705
-
-
Ogawa, N.1
List, J.F.2
Habener, J.F.3
Maki, T.4
-
9
-
-
33846410255
-
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
-
Tarbell KV, Petit L, Zuo X, Toy P, Luo X, et al. (2007) Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med 204: 191-201.
-
(2007)
J Exp Med
, vol.204
, pp. 191-201
-
-
Tarbell, K.V.1
Petit, L.2
Zuo, X.3
Toy, P.4
Luo, X.5
-
10
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, et al. (2002) Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med 346: 1692-1698.
-
(2002)
N Engl J Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
Poumian-Ruiz, E.4
Taylor, L.5
-
11
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
Keymeulen B, Vandemeulebroucke E, Ziegler AG, Mathieu C, Kaufman L, et al. (2005) Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 352: 2598-2608.
-
(2005)
N Engl J Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
Vandemeulebroucke, E.2
Ziegler, A.G.3
Mathieu, C.4
Kaufman, L.5
-
12
-
-
0025020303
-
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1
-
Jacob CO, Aiso S, Michie SA, McDevitt HO, Acha-Orbea H, (1990) Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A 87: 968-972.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 968-972
-
-
Jacob, C.O.1
Aiso, S.2
Michie, S.A.3
McDevitt, H.O.4
Acha-Orbea, H.5
-
13
-
-
0027990811
-
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process
-
Yang XD, Tisch R, Singer SM, Cao ZA, Liblau RS, et al. (1994) Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med 180: 995-1004.
-
(1994)
J Exp Med
, vol.180
, pp. 995-1004
-
-
Yang, X.D.1
Tisch, R.2
Singer, S.M.3
Cao, Z.A.4
Liblau, R.S.5
-
14
-
-
0032813549
-
Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice
-
Green EA, Flavell RA, (1999) Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice. Immunol Rev 169: 11-22.
-
(1999)
Immunol Rev
, vol.169
, pp. 11-22
-
-
Green, E.A.1
Flavell, R.A.2
-
15
-
-
51649084550
-
Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism
-
Ban L, Zhang J, Wang L, Kuhtreiber W, Burger D, et al. (2008) Selective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonism. Proc Natl Acad Sci U S A 105: 13644-13649.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13644-13649
-
-
Ban, L.1
Zhang, J.2
Wang, L.3
Kuhtreiber, W.4
Burger, D.5
-
16
-
-
0242582180
-
Islet regeneration during the reversal of autoimmune diabetes in NOD mice
-
Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL, (2003) Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 302: 1223-1227.
-
(2003)
Science
, vol.302
, pp. 1223-1227
-
-
Kodama, S.1
Kuhtreiber, W.2
Fujimura, S.3
Dale, E.A.4
Faustman, D.L.5
-
17
-
-
0025647147
-
Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages
-
Hutchings P, Rosen H, O'Reilly L, Simpson E, Gordon S, et al. (1990) Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages. Nature 348: 639-642.
-
(1990)
Nature
, vol.348
, pp. 639-642
-
-
Hutchings, P.1
Rosen, H.2
O'Reilly, L.3
Simpson, E.4
Gordon, S.5
-
18
-
-
0024211490
-
Evidence for initial involvement of macrophage in development of insulitis in NOD mice
-
Lee KU, Amano K, Yoon JW, (1988) Evidence for initial involvement of macrophage in development of insulitis in NOD mice. Diabetes 37: 989-991.
-
(1988)
Diabetes
, vol.37
, pp. 989-991
-
-
Lee, K.U.1
Amano, K.2
Yoon, J.W.3
-
19
-
-
0028031569
-
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha
-
Hotamisligil GS, Budavari A, Murray D, Spiegelman BM, (1994) Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J Clin Invest 94: 1543-1549.
-
(1994)
J Clin Invest
, vol.94
, pp. 1543-1549
-
-
Hotamisligil, G.S.1
Budavari, A.2
Murray, D.3
Spiegelman, B.M.4
-
20
-
-
67650079482
-
Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study
-
Mastrandrea L, Yu J, Behrens T, Buchlis J, Albini C, et al. (2009) Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study. Diabetes Care 32: 1244-1249.
-
(2009)
Diabetes Care
, vol.32
, pp. 1244-1249
-
-
Mastrandrea, L.1
Yu, J.2
Behrens, T.3
Buchlis, J.4
Albini, C.5
-
21
-
-
67650766977
-
Translating molecular insights in autoimmunity into effective therapy
-
Feldmann M, (2009) Translating molecular insights in autoimmunity into effective therapy. Annu Rev Immunol 27: 1-27.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 1-27
-
-
Feldmann, M.1
-
22
-
-
23844524767
-
Gene signatures of progression and metastasis in renal cell cancer
-
Jones J, Otu H, Spentzos D, Kolia S, Inan M, et al. (2005) Gene signatures of progression and metastasis in renal cell cancer. Clin Cancer Res 11: 5730-5739.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5730-5739
-
-
Jones, J.1
Otu, H.2
Spentzos, D.3
Kolia, S.4
Inan, M.5
-
23
-
-
24644512209
-
Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis
-
Wilson CL, Miller CJ, (2005) Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis. Bioinformatics 21: 3683-3685.
-
(2005)
Bioinformatics
, vol.21
, pp. 3683-3685
-
-
Wilson, C.L.1
Miller, C.J.2
-
24
-
-
33751006151
-
RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis
-
Hong F, Breitling R, McEntee CW, Wittner BS, Nemhauser JL, et al. (2006) RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis. Bioinformatics 22: 2825-2827.
-
(2006)
Bioinformatics
, vol.22
, pp. 2825-2827
-
-
Hong, F.1
Breitling, R.2
McEntee, C.W.3
Wittner, B.S.4
Nemhauser, J.L.5
-
25
-
-
79960088916
-
Insulitis in human type 1 diabetes: The quest for an elusive lesion
-
In't Veld P, (2011) Insulitis in human type 1 diabetes: The quest for an elusive lesion. Islets 3: 131-138.
-
(2011)
Islets
, vol.3
, pp. 131-138
-
-
In't Veld, P.1
-
26
-
-
0022408439
-
An improved method for isolation of mouse pancreatic islets
-
Gotoh M, Maki T, Kiyoizumi T, Satomi S, Monaco AP, (1985) An improved method for isolation of mouse pancreatic islets. Transplantation 40: 437-438.
-
(1985)
Transplantation
, vol.40
, pp. 437-438
-
-
Gotoh, M.1
Maki, T.2
Kiyoizumi, T.3
Satomi, S.4
Monaco, A.P.5
-
27
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF, Bonner-Weir S, (1999) Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48: 2270-2276.
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
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