Periodic leg movements in sleep in elderly patients with Parkinsonism and Alzheimer's disease

European Journal of Neurology

Volumn 19, Issue 6, 2012, Pages 918-923

  Bliwise, D L ^a   Trotti, L M ^a   Yesavage, J A ^b   Rye, D B ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Parkinsonism; Periodic leg movements in sleep; Restless legs syndrome; Willis Ekbom disease

Indexed keywords

DOPAMINE; LEVODOPA;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CAREGIVER; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; FEMALE; HUMAN; LEG MOVEMENT; MAJOR CLINICAL STUDY; MALE; PARKINSONISM; PERIODIC LIMB MOVEMENT DISORDER; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SYMPTOM;

AGED; ALZHEIMER DISEASE; ELECTROMYOGRAPHY; FEMALE; HUMANS; LOWER EXTREMITY; MALE; MIDDLE AGED; MOVEMENT; PARKINSONIAN DISORDERS; POLYSOMNOGRAPHY; PSYCHIATRIC STATUS RATING SCALES; RESIDENCE CHARACTERISTICS; RESTLESS LEGS SYNDROME; SEVERITY OF ILLNESS INDEX;

EID: 84860917840     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2012.03673.x     Document Type: Article

References (47)

1. Bliwise DL. Restless legs syndrome and periodic limb movements in the elderly with and without dementia. In: Hening WA, Allen RP, Chokroverty S, Earley CJ eds. Restless Legs Syndrome. Philadelphia: Elsevier/Saunders, 2009: 178-184.
2. Benes H, Kurella B, Kummer J, Kazenwadel J, Selzer R, Kohnen R. Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomized, multicenter, crossover trial. Sleep 1999; 22: 1073-1081.
3. Allen R, Becker PM, Bogan R, et al. Ropinirole decreases periodic leg movements and improves sleep parameters in patients with restless legs syndrome. Sleep 2004; 27: 907-914.
4. Partinen M, Hirvonen K, Jama L, et al. Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study-the PRELUDE study. Sleep Med 2006; 7: 407-417.
5. Routtinen HM, Partinen M, Hublin C, et al. An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. Neurology 2000; 54: 502-504.
6. Staedt J, Stoppe G, Kogler A, et al. Dopamine D2 receptor alteration in patients with periodic leg movements in sleep (nocturnal myoclonus). J Neural Trans [Gen Sect] 1993; 93: 71-74.
7. Michaud M, Soucy JP, Chabli A, Lavigne G, Montplaisir J. SPECT imaging of striatal pre- and postsynaptic dopaminergic status in restless legs syndrome with periodic leg movements in sleep. J Neurol 2002; 249: 164-170.
8. Eisensehr I, Wetter TC, Linke R, et al. Normal IPT and IBZM SPECT in drug-naïve and levodopa-treated idiopathic restless legs syndrome. Neurology 2001; 57: 1307-1309.
9. Earley CJ, Hyland K, Allen RP. CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome. Mov Disord 2001; 16: 144-149.
10. Stiasny-Kolster K, Moller JC, Zschocke J, et al. Normal dopaminergic and serotonergic metabolites in cerebrospinal fluid and blood of restless legs syndrome patients. Mov Disord 2004; 19: 192-196.
11. Gilman S, Low P, Quinn N, et al. Consensus statement on the diagnosis of multiple system atrophy. Clin Auton Res 1998; 8: 359-362.
12. Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967; 17: 427-442.
13. Hobson DE, Lang AE, Martin WRW, Razmy A, Rivest J, Fleming J. Excessive daytime sleepiness and sudden onset sleep in Parkinson's disease: a survey by the Canadian Movement Disorders Group. JAMA 2002; 287: 455-463.
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadian EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-944.
15. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res 1975; 12: 189-198.
16. Bliwise DL, Bliwise NG, Partinen M, Pursley AM, Dement WC. Sleep apnea and mortality in an aged cohort. Am J Public Health 1988; 78: 544-547.
17. Bliwise DL. Sleep and aging. In: Pressman MR, Orr WC eds. Understanding Sleep: The Evaluation and Treatment of Sleep Disorders. Washington, DC: American Psychological Association, 1997: 441-464.
18. Bliwise DL. Epidemiology of age-dependence of sleep disordered breathing in old age. Sleep Med Clin 2009; 4: 57-64.
19. Bliwise DL, Williams ML, Irbe D, Ansari FP, Rye DB. Inter-rater reliability for identification of REM sleep in Parkinson's disease. Sleep 2000; 23: 671-676.
20. American Sleep Disorders Association. EEG arousals: scoring rules and examples: a preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep 1992; 15: 173-184.
21. American Sleep Disorders Association. Atlas and scoring rules. Sleep 1993; 16: 748-759.
22. Wetter T, Collado-Seidel V, Pollmacher T, Yassouridis A, Trenkwalder C. Sleep and periodic leg movement patterns in drug-free patients with Parkinson's disease and multiple system atrophy. Sleep 2000; 23: 361-367.
23. Freeman AAH, Rye DB. The brain's dopamine systems and their relevance to restless legs syndrome. In: Hening WA, Allen RP, Chokroverty S, Earley CJ eds. Restless Legs Syndrome. Philadelphia: Elsevier/Saunders, 2009: 69-77.
24. Rottach KG, Schaner BM, Kirch MH, et al. Restless legs syndrome as side effect of second generation antidepressants. J Psychiatr Res 2008; 43: 70-75.
25. Yang C, White DP, Winkelman JW. Anti-depressants and periodic leg movements of sleep. Biol Psychiatry 2005; 58: 510-514.
26. Buchbuhrer MJ, Gunzel J. Nonpharmacologic considerations and treatment of restless legs syndrome. In: Hening WA, Allen RP, Chokroverty S, Earley CJ eds. Restless Legs Syndrome. Philadelphia: Elsevier/Saunders, 2009: 228-237.
27. Trotti LM, Rye DB. Restless legs syndrome. Handb Clin Neurol 2011; 100: 661-673.
28. Bliwise DL, Keenan S, Burnburg D, et al. Inter-rater reliability for scoring periodic leg movements in sleep. Sleep 1991; 14: 249-251.
29. Whitney CW, Gottlieb DJ, Redline S, et al. Reliability of scoring respiratory disturbance indices and sleep staging. Sleep 1998; 21: 749-757.
30. Winkelman JW. The evoked heart rate response to periodic leg movements of sleep. Sleep 1999; 22: 575-580.
31. Joyce JN, Myers AJ, Gurevich E. Dopamine D2 receptor bands in normal human temporal cortex are absent in Alzheimer's disease. Brain Res 1998; 784: 7-17.
32. Ryoo HL, Joyce JN. Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease. J Comp Neurol 1994; 348: 94-110.
33. Kemppainen N, Ruottinen H, Nagren K, Rinne JO. PET shows that striatal dopamine D1 and D2 receptors are differentially affected in AD. Neurology 2000; 55: 205-209.
34. Pizzolato G, Chierichetti F, Fabbri M, et al. Reduced striatal dopamine receptors in Alzheimer's disease: single photon emission tomography study with the D2 tracer [123I]-IBZM. Neurology 1996; 47: 1065-1068.
35. Reeves S, Brown R, Howard R, Grasby P. Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer's disease. Neurology 2009; 72: 528-534.
36. Pritchard AL, Pritchard CW, Bentham P, Lendon CL. Investigation of the role of the dopamine transporter in susceptibility to behavioural and psychological symptoms of patients with probable Alzheimer's disease. Dement Geriatr Cogn Disord 2008; 26: 257-260.
37. Sweet RA, Hamilton RL, Healy MT, et al. Alterations of striatal dopamine receptor binding in Alzheimer disease are associated with Lewy body pathology and antemortem psychosis. Arch Neurol 2001; 58: 466-472.
38. Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diagnostic criteria, special considerations and epidemiology. A report from the Restless Legs Syndrome Diagnosis and Epidemiology Workshop at the National Institutes of Health. Sleep Med 2003; 4: 101-119.
39. Boeve BF, Silber MH, Saper CB, et al. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 2007; 130: 2770-2788.
40. Iranzo A, Comella CL, Santamaria J, Oertel W. Restless legs syndrome in Parkinson's disease and other neurodegenerative diseases of the central nervous system. Mov Disord 2007; 22(Suppl.): S424-S430.
41. Rongve A, Boeve BF, Aarsland D. Frequency and correlates of caregiver-reported sleep disturbances in a sample of persons with early dementia. J Am Geriatr Soc 2010; 58: 480-486.
42. Tractenberg RE, Singer CM, Kaye JA. Symptoms of sleep disturbance in persons with Alzheimer's disease and normal elderly. J Sleep Res 2005; 14: 177-185.
43. Tanaka Y, Meguro K, Yamaguchi S, et al. Decreased striatal D2 receptor density associated with severe behavioral abnormality in Alzheimer's disease. Ann Nucl Med 2003; 17: 567-573.
44. Meguro K, Yamaguchi S, Itoh M, Fujiwara T, Yamadori A. Striatal dopamine metabolism correlated with frontotemporal glucose utilization in Alzheimer's disease: a double-tracer PET study. Neurology 1997; 49: 941-945.
45. Richards K, Shue VM, Beck CK, Lambert CW, Bliwise DL. Restless legs syndrome risk factors, behaviors and diagnoses in persons with elderly to moderate dementia and sleep disturbance. Behav Sleep Med 2010; 8: 48-61.
46. Rose KM, Beck C, Tsai P-F, et al. Sleep disturbances and nocturnal agitation behaviors in older adults with dementia. Sleep 2011; 34: 779-786.
47. Cohen-Mansfield J. Agitated behaviors in the elderly. II. Preliminary results in the cognitively deteriorated. J Am Geriatr Soc 1986; 34: 722-727.