Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: The role of targeting signals and of protein-protein interactions

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 2164-2174

  Fillatre, Jonathan ^a   Delacour, Delphine ^a   Van Hove, Lucie ^a   Bagarre, Thomas ^a   Houssin, Nathalie ^a   Soulika, Marina ^a   Veitia, Reiner A ^a   Moreau, Jacques ^a  

^a INSTITUT JACQUES MONOD   (France)

Author keywords

Actin; Centrosome; NLS

Indexed keywords

ACTIN; BINDING PROTEIN; ELECTROPHILE; GLUTATHIONE; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; PROTEIN RALBP1; RAL PROTEIN; RAS PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CENTROSOME; CYTOSKELETON; EMBRYO; ENDOCYTOSIS; GASTRULATION; GENE EXPRESSION REGULATION; HELA CELL; MITOSIS; MITOSIS SPINDLE; MOLECULAR DYNAMICS; MULTIDRUG RESISTANCE; MUTATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; DNA PRIMERS; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; SEQUENCE HOMOLOGY, AMINO ACID; SUBCELLULAR FRACTIONS; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 84860905589     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-196451     Document Type: Article

References (28)

1. Prieve, M. G., and Waterman, M. L. (1999) Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression. Mol. Cell. Biol. 19, 4503-4515 (Pubitemid 29242023)
2. Jans, D. A., Xiao, C. Y., and Lam, M. H. (2000) Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays 22, 532-544 (Pubitemid 30387974)
3. Omura, T. (1998) Mitochondria-targeting sequence, a multirole sorting sequence recognized at all steps of protein import into mitochondria. J. Biochem. 123, 1010-1016
4. Pechlivanis, M., and Kuhlmann, J. (2006) Hydrophobic modifications of Ras proteins by isoprenoid groups and fatty acids-more than just membrane anchoring. Biochim. Biophys. Acta 1764, 1914-1931 (Pubitemid 44895028)
5. Andreou, A. M., and Tavernarakis, N. (2009) SUMOylation and cell signalling. Biotechnol. J. 4, 1740-1752
6. Hicks, S. W., and Machamer, C. E. (2002) The NH2-terminal domain of Golgin-160 contains both Golgi and nuclear targeting information. J. Biol. Chem. 277, 35833-35839
7. Omerovic, J., and Prior, I. A. (2009) Compartmentalized signalling: Ras proteins and signalling nanoclusters. FEBS J. 276, 1817-1825
8. Philips, M. R. (2005) Compartmentalized signalling of Ras. Biochem. Soc. Trans. 33, 657-661
9. Chiu, V. K., Bivona, T., Hach, A., Sajous, J. B., Silletti, J., Wiener, H., Johnson, R. L., 2nd, Cox, A. D., and Philips, M. R. (2002) Ras signalling on the endoplasmic reticulum and the Golgi. Nat. Cell Biol. 4, 343-350 (Pubitemid 34521029)
10. Jullien-Flores, V., Mahé, Y., Mirey, G., Leprince, C., Meunier-Bisceuil, B., Sorkin, A., and Camonis, J. H. (2000) RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endoocytosis. J. Cell Sci. 113, 2837-2844
11. Ikeda, M., Ishida, O., Hinoi, T., Kishida, S., and Kikuchi, A. (1998) Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. J. Biol. Chem. 273, 814-821 (Pubitemid 28049171)
12. Boissel, L., Houssin, N., Chikh, A., Rynditch, A., Van Hove, L., and Moreau, J. (2007) Recruitment of Cdc42 through the GAP domain of RLIP participates in remodeling of the actin cytoskeleton and is involved in Xenopus gastrulation. Dev. Biol. 312, 331-343 (Pubitemid 350180760)
13. Awasthi, S., Cheng, J., Singhal, S. S., Saini, M. K., Pandya, U., Pikula, S., Bandorowicz-Pikula, J., Singh, S. V., Zimniak, P., and Awasthi, Y. C. (2000) Novel function of human RLIP76: ATPdependent transport of glutathione conjugates and doxorubicin. Biochemistry 39, 9327-9334 (Pubitemid 30626323)
14. Singhal, S. S., Awasthi, Y. C., and Awasthi, S. (2006) Regression of melanoma in a murine model by RLIP76 depletion. Cancer Res. 66, 2354-2360
15. Singhal, S. S., Roth, C., Leake, K., Singhal, J., Yadav, S., and Awasthi, S. (2009) Regression of prostate cancer xenografts by RLIP76 depletion. Biochem. Pharmacol. 77, 1074-1083
16. Gurdon, J. B. (1967) African clawed frogs. In Methods in Developmental Biology (Wilt, F. H., and Wessels, N. K., eds) pp. 75-84, Crowell, New York
17. Lebreton, S., Boissel, L., Iouzalen, N., and Moreau, J. (2004) RLIP mediates downstream signalling from RalB to the actin cytoskeleton during Xenopus early development. Mech. Dev. 121, 1481-1494 (Pubitemid 39423627)
18. Gusse, M., Ghysdael, J., Evan, G., Soussi, T., and Mechali, M. (1989) Translocation of a store maternal cytoplasmic c-myc protein into nuclei during early development. Mol. Cell. Biol. 9, 5395-5403 (Pubitemid 20004355)
19. Moreau, J., Lebreton, S., Iouzalen, N., and Mechali, M. (1999) Characterization of Xenopus RalB and its involvement in F-actin control during early development. Dev. Biol. 209, 268-281 (Pubitemid 29230879)
20. Lebreton, S., Boissel, L., and Moreau, J. (2003) Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the signalling pathway. J. Cell Sci. 116, 4651-4662 (Pubitemid 37461619)
21. Sato, N., Tsuruma, R., Imoto, S., Sekine, Y., Muromoto, R., Sugiyama, K., and Matsuda, T. (2005) Nuclear retention of STAT3 through the coiled-coil domain regulates its activity. Biochem. Biophys. Res. Commun. 336, 617-624 (Pubitemid 41267271)
22. Imasaki, T., Shimizu, T., Hashimoto, H., Hidaka, Y., Kose, S., Imamoto, N., Yamada, M., and Sato, M. (2007) Structural basis for substrate recognition and dissociation by human transportin 1. Mol. Cell 28, 57-67 (Pubitemid 47531969)
23. Cascone, I., Selimoglu, R., Ozdemir, C., Del Nery, E., Yeaman, C., White, M., and Camonis, J. (2008) Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs. EMBO J. 27, 2375-2387
24. Cantor, S. B., Urano, T., and Feig, L. A. (1995) Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases. Mol. Cell. Biol. 15, 4578-34584
25. Awasthi, S., Singhal, S. S., Awasthi, Y. C., Martin, B., Woo, J. H., Cunningham, C. C., and Frankel, A. E. (2008) RLIP76 and cancer. Clin. Cancer Res. 14, 4372-4377
26. Quaroni, A., and Paul, E. C. (1999) Cytocentrin is a Ral-binding protein involved in the assembly and function of the mitotic apparatus. J. Cell Sci. 112, 707-718 (Pubitemid 29141990)
27. Han, K., Kim, M. H., Seeburg, D., Seo, J., Verpelli, C., Han, S., Chung, H. S., Ko, J., Lee, H. W., Kim, K., Heo, W. D., Meyer, T., Kim, H., Sala, C., Choi, S. Y., Sheng, M., and Kim, E. (2009) Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD. PLoS Biol. 7, e1000187
28. Cocquet, J., Chong, A., Zhang, G., and Veitia, R. A. (2006) Reverse transcriptase template switching and false alternative transcripts. Genomics 88, 127-131 (Pubitemid 44183763)