Extensively hydrolysed casein formula supplemented with Lactobacillus rhamnosus GG maintains hypoallergenic status: Randomised double-blind, placebo-controlled crossover trial

BMJ Open

Volumn 2, Issue 2, 2012, Pages

  Muraro, Antonella ^a   Hoekstra, Maarten O ^b   Meijer, Yolanda ^c   Lifschitz, Carlos ^d   Wampler, Jennifer L ^e   Harris, Cheryl ^e   Scalabrin, Deolinda M F ^e  

^a UNIVERSITY OF PADOVA   (Italy)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d HOSPITAL ITALIANO DE BUENOS AIRES   (Argentina)

^e Clinical Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN HYDROLYSATE; PROBIOTIC AGENT;

ALLERGENICITY; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HYPOALLERGENICITY; INFANT; LACTOBACILLUS RHAMNOSUS; MALE; MILK ALLERGY; MULTICENTER STUDY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD;

EID: 84860891446     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2011-000637     Document Type: Article

References (31)

1. Gartner LM, Morton J, Lawrence RA, et al. Breastfeeding and the use of human milk. Pediatrics 2005;115:496-506.
2. Boyce JA, Assa'ad A, Burks AW, et al NIAID-Sponsored Expert Panel. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol 2010;126(6 Suppl):S1-58.
3. Höst A, Halken S, Jacobsen HP, et al. Clinical course of cow's milk protein allergy/intolerance and atopic diseases in childhood. Pediatr Allergy Immunol 2002;13(Suppl 15):23-8. (Pubitemid 36125081)
4. Schrander JJ, van den Bogart JP, Forget PP, et al. Cow's milk protein intolerance in infants under 1 year of age: a prospective epidemiological study. Eur J Pediatr 1993;152:640-4. (Pubitemid 23211146)
5. Bindslev-Jensen C, Ballmer-Weber BK, Bengtsson U, et al. Standardization of food challenges in patients with immediate reactions to foodseposition paper from the European Academy of Allergology and Clinical Immunology. Allergy 2004;59:690-7. (Pubitemid 38850342)
6. Garcia-Ara C, Boyano-Martinez T, Diaz-Pena JM, et al. Specific IgE levels in the diagnosis of immediate hypersensitivity to cows' milk protein in the infant. J Allergy Clin Immunol 2001;107:185-90. (Pubitemid 32105264)
7. Sampson HA. Utility of food-specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol 2001;107:891-6. (Pubitemid 32436924)
8. Vandenplas Y, Koletzko S, Isolauri E, et al. Guidelines for the diagnosis and management of cow's milk protein allergy in infants. Arch Dis Child 2007;92:902-8. (Pubitemid 47535455)
9. Bhatia J, Greer F. Use of soy protein-based formulas in infant feeding. Pediatrics 2008;121:1062-8.
10. Committee on Nutrition. American Academy of Pediatrics. Hypoallergenic infant formulas. Pediatrics 2000;106:346-9.
11. Oldæus G, Björkstén B, Einarsson R, et al. Antigenicity and allergenicity of cow milk hydrolysates intended for infant feeding. Pediatr Allergy Immunol 1991;2:156-64.
12. Oldæus G, Bradley CK, Björkstén B, et al. Allergenicity screening of "hypoallergenic" milk-based formulas. J Allergy Clin Immunol 1992;90:133-5.
13. Sampson HA, Bernhisel-Broadbent J, Yang E, et al. Safety of casein hydrolysate formula in children with cow milk allergy. J Pediatr 1991;118:520-5.
14. Isolauri E, Sutas Y, Makinen-Kiljunen S, et al. Efficacy and safety of hydrolyzed cow milk and amino acid-derived formulas in infants with cow milk allergy. J Pediatr 1995;127:550-7.
15. Host A, Husby S, Hansen LG, et al. Bovine beta-lactoglobulin in human milk from atopic and non-atopic mothers. Relationship to maternal intake of homogenized and unhomogenized milk. Clin Exp Allergy 1990;20:383-7. (Pubitemid 20208475)
16. Host A, Koletzko B, Dreborg S, et al. Dietary products used in infants for treatment and prevention of food allergy. Joint statement of the European Society for Paediatric Allergology and Clinical Immunology (ESPACI) Committee on Hypoallergenic Formulas and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Committee on Nutrition. Arch Dis Child 1999;81:80-4. (Pubitemid 29307465)
17. Guarner F, Schaafsma GJ. Probiotics. Int J Food Microbiol 1998;39:237-8. (Pubitemid 28132640)
18. Isolauri E, Arvola T, Sutas Y, et al. Probiotics in the management of atopic eczema. Clin Exp Allergy 2000;30:1604-10.
19. Viljanen M, Savilahti E, Haahtela T, et al. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy 2005;60:494-500. (Pubitemid 40332976)
20. Baldassarre ME, Laforgia N, Fanelli M, et al. Lactobacillus GG improves recovery in infants with blood in the stools and presumptive allergic colitis compared with extensively hydrolyzed formula alone. J Pediatr 2010;156:397-401.
21. Canani RB, Nocerino R, Terrin G, et al. Effect of extensively hydrolyzed casein formula supplemented with Lactobacillus GG on tolerance acquisition in infants with cow's milk allergy: a randomized trial. J Allergy Clin Immunol 2012;129:580-2.e5
22. Petschow BW, Figueroa R, Harris CL, et al. Effects of feeding an infant formula containing Lactobacillus GG on the colonization of the intestine: a dose-response study in healthy infants. J Clin Gastroenterol 2005;39:786-90. (Pubitemid 41361896)
23. Scalabrin DM, Johnston WH, Hoffman DR, et al. Growth and tolerance of healthy term infants receiving hydrolyzed infant formulas supplemented with Lactobacillus rhamnosus GG: randomized, double-blind, controlled trial. Clin Pediatr (Phila) 2009;48:734-44.
24. Burks W, Jones SM, Berseth CL, et al. Hypoallergenicity and effects on growth and tolerance of a new amino acid-based formula with docosahexaenoic acid and arachidonic acid. J Pediatr 2008;153:266-71.
25. Gorbach SL. The discovery of Lactobacillus GG. (Lactobacillus GG). Nutr Today 1996;31:5S.
26. Stansbridge EM, Walker V, Hall MA, et al. Effects of feeding premature infants with Lactobacillus GG on gut fermentation. Arch Dis Child 1993;69:488-92. (Pubitemid 23357108)
27. Laitinen K, Kalliomaki M, Poussa T, et al. Evaluation of diet and growth in children with and without atopic eczema: follow-up study from birth to 4 years. Br J Nutr 2005;94:565-74. (Pubitemid 41555498)
28. Rinne M, Kalliomaki M, Salminen S, et al. Probiotic intervention in the first months of life: short-term effects on gastrointestinal symptoms and long-term effects on gut microbiota. J Pediatr Gastroenterol Nutr 2006;43:200-5. (Pubitemid 44180505)
29. Pessi T, Sutas Y, Hurme M, et al. Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy 2000;30:1804-8. (Pubitemid 32011762)
30. Kalliomä ki M, Salminen S, Poussa T, et al. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J Allergy Clin Immunol 2007;119:1019-21.
31. Majamaa H, Isolauri E. Probiotics: a novel approach in the management of food allergy. J Allergy Clin Immunol 1997;99:179-85. (Pubitemid 27091565)