Continuous intake of a high-fat diet beyond one generation promotes lipid accumulation in liver and white adipose tissue of female mice

Journal of Nutritional Biochemistry

Volumn 23, Issue 6, 2012, Pages 640-645

  Takasaki, Mariko ^a   Honma, Taro ^a   Yanaka, Miyuki ^a   Sato, Kenta ^a   Shinohara, Nahoko ^a   Ito, Junya ^a   Tanaka, Yurie ^a   Tsuduki, Tsuyoshi ^a   Ikeda, Ikuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Cdkn1a; Fatty liver; High fat diet; Insulin resistance; Obesity; Offspring

Indexed keywords

ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; FATTY ACID SYNTHASE; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; INSULIN; LIPID; MALATE DEHYDROGENASE (DECARBOXYLATING); MESSENGER RNA;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; DIETARY INTAKE; ENERGY; ENZYME ACTIVITY; FATTY ACID METABOLISM; FEMALE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIVER CELL; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PROGENY; TISSUE METABOLISM; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD GLUCOSE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DIET, HIGH-FAT; DIETARY FATS; FATTY LIVER; FEMALE; HYPERINSULINISM; INSULIN; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED ICR; OBESITY;

MUS;

EID: 84860889537     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.03.008     Document Type: Article

References (34)

1. Haslam D., James P. Obesity. Lancet 2005, 366:1197-1209.
2. Kelly T., Yang W., Chen C.S., Reynolds K., He J. Global burden of obesity in 2005 and projections to 2030. Int J Obes 2008, 32:1431-1437.
3. Wang Y., Beydoun M.A., Liang L., Caballero B., Kumanyika S.K. Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic. Obesity 2008, 16:2323-2330.
4. Howie G.J., Sloboda D.M., Kamal T., Vickers M.H. Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet. J Physiol 2009, 587:905-915.
5. Maso L.D., Zucchetto A., Vecchia C.L., Montella M., Conti E., Canzonieri V., et al. Prostate cancer and body size at different ages: an Italian multicentre case-control study. Br J Cancer 2004, 90:2176-2180.
6. Shankar K., Harrell A., Liu X., Gilchrist J.M., Ronis M.J., Badger T.M. Maternal obesity at conception programs obesity in the offspring. Am J Physiol Regul Integr Comp Physiol 2008, 294:R528-R538.
7. Bayol S.A., Simbi B.H., Bertrand J.A., Stickland N.C. Offspring from mothers fed a 'junk food' diet in pregnancy and lactation exhibit exacerbated adiposity that is more pronounced in females. J Physiol 2008, 586:3219-3230.
8. McCurdy C.E., Bishop J.M., Williams S.M., Grayson B.E., Smith M.S., Friedman J.E., et al. Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J Clin Invest 2009, 119:323-335.
9. Samuelsson A.M., Matthews P.A., Argenton M., Christie M.R., McConnell J.M., Jansen E.H., et al. Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance. Hypertension 2008, 51:383-392.
10. Khan I.Y., Taylor P.D., Dekou V., Seed P.T., Lakasing L., Graham D., et al. Gender-linked hypertension in offspring of lard-fed pregnant rats. Hypertension 2003, 41:168-175.
11. Tsuzuki T., Tokuyama Y., Igarashi M., Miyazawa T. Tumor growth suppression by α-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis 2004, 25:1417-1425.
12. Tsuzuki T., Kawakami Y., Suzuki Y., Abe R., Nakagawa K., Miyazawa T. Intake of conjugated eicosapentaenoic acid suppresses lipid accumulation of liver and epididymal adipose tissue in rats. Lipids 2005, 40:1117-1123.
13. Tsuzuki T., Kawakami Y., Nakagawa K., Miyazawa T. Conjugated docosahexaenoic acid inhibits lipid accumulation in rats. J Nutr Biochem 2006, 17:518-524.
14. Rouser G., Fkeischer S., Yamamoto A. Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids 1970, 5:494-496.
15. Ide T., Kobatashi H., Ashakumary L., Rouyer I.A., Takahashi Y., Aoyama T., et al. Comparative effects of perilla and fish oils on the activity and gene expression of fatty acid oxidation enzymes in rat liver. Biochim Biophys Acta 2000, 1485:23-35.
16. Shibata A., Nakagawa K., Sookwong P., Tsuzuki T., Oikawa S., Miyazawa T. Tumor anti-angiogenic effect and mechanism of action of δ-tocotrienol. Biochem Pharmacol 2008, 76:330-339.
17. Tsuzuki T., Kambe T., Shibata A., Kawakami Y., Nakagawa K., Miyazawa T. Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells. Biochim Biophys Acta 2007, 1771:20-30.
18. Parekh S., Anania F.A. Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease. Gastroenterology 2007, 132:2191-2207.
19. Paulauskis J.D., Sul H.S. Hormonal regulation of mouse fatty acid synthase gene transcription in liver. J Biol Chem 1989, 264:574-577.
20. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002, 346:1221-1231.
21. 31P NMR studies on the effects of increased plasma free fatty acids on intramuscular glucose metabolism in the awake rat. J Biol Chem 1997, 272:10464-10473.
22. Hajer G.R., van Haeften T.W., Visseren F.L. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J 2008, 29:2959-2971.
23. Harper J.W., Elledge S.J., Keyomarsi K., Dynlacht B., Tsai L.H., Zhang P., et al. Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 1995, 6:387-400.
24. Xiong Y., Hannon G.J., Zhang H., Casso D., Kobayashi R., Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993, 366:701-704.
25. Yahagi N., Shimano H., Matsuzaka T., Najima Y., Sekiya M., Nakagawa Y., et al. p53 activation in adipocytes of obese mice. J Biol Chem 2003, 278:25395-25400.
26. Yahagi N., Shimano H., Matsuzaka T., Sekiya M., Najima Y., Okazaki S., et al. p53 involvement in the pathogenesis of fatty liver disease. J Biol Chem 2004, 279:20571-20575.
27. Inoue N., Yahagi N., Yamamoto T., Ishikawa M., Watanabe K., Matsuzaka T., et al. Cyclin-dependent kinase Inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance. J Biol Chem 2008, 283:21220-21229.
28. Gu W., Roeder R.G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 c-terminal domain. Cell 1997, 90:595-606.
29. Siliciano J.D., Canman C.E., Taya Y., Sakaguchi K., Appella E., Kastan M.B. DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev 1997, 11:3471-3481.
30. Park E.A., Mynatt R.L., Cook G.A., Kashfi K. Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic carnitine palmitoyltransferase-I. Biochem J 1995, 310:853-858.
31. Shefer S., Hauser S., Bekersky I., Mosbach E.H. Biochemical site of regulation of bile acid biosynthesis in the rat. J Lipid Res 1970, 11:404-411.
32. Dunn G.A., Bale T.L. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 2009, 150:4999-5009.
33. Plagemann A., Harder T., Brunn M., Harder A., Roepke K., Wittrock-Staar M., et al. Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol 2009, 587:4963-4976.
34. Jimenez-Chillaron J.C., Isganaitis E., Charalambous M., Gesta S., Pentinat-Pelegrin T., Faucette R.R., et al. Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. Diabetes 2009, 58:460-468.