Phosphatidylinositol 4,5-bisphosphate increases Ca2+ affinity of synaptotagmin-1 by 40-fold

Journal of Biological Chemistry

Volumn 287, Issue 20, 2012, Pages 16447-16453

  Van Bogaart, Geert Den ^a   Meyenberg, Karsten ^b   Diederichsen, Ulf ^b   Jahn, Reinhard ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIONIC PHOSPHOLIPIDS; COOPERATIVE BINDING; COOPERATIVITY; DISSOCIATION CONSTANT; MICRO-SCALES; NEUROTRANSMITTER RELEASE; PHOSPHATIDYLINOSITOL 4 ,5-BISPHOSPHATE; SYNAPTOTAGMINS;

BIOCHEMISTRY; DISSOCIATION; PHOSPHOLIPIDS;

CALCIUM;

CALCIUM; DIOLEOYLPHOSPHATIDYLCHOLINE; LIPOSOME; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; SYNAPTOTAGMIN I;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; CHEMICAL PROCEDURES; CONTROLLED STUDY; DISSOCIATION CONSTANT; LIPID COMPOSITION; MICROSCALE THERMOPHORESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTITATIVE ANALYSIS;

ANIMALS; CALCIUM; NEUROTRANSMITTER AGENTS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SYNAPTOTAGMIN I;

EID: 84860871594     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.343418     Document Type: Article

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