Pax6 interacts with SPARC and TGF-β in murine eyes

Molecular Vision

Volumn 18, Issue , 2012, Pages 951-956

  Shubham, Kumar ^a   Mishra, Rajnikant ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

OSTEONECTIN; SMAD PROTEIN; TRANSCRIPTION FACTOR PAX6; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EYE; EYE DEVELOPMENT; FLUORESCENCE MICROSCOPY; FUNCTIONAL ANATOMY; IMMUNOPRECIPITATION; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; EYE; EYE PROTEINS; HOMEODOMAIN PROTEINS; IMMUNOPRECIPITATION; MICE; MICROSCOPY, FLUORESCENCE; MICROTOMY; OSTEONECTIN; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TISSUE EMBEDDING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84860871002     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Halder G, Callaerts P, Gehring WJ. New perspectives on eye evolution. Curr Opin Genet Dev 1995; 5:602-9. [PMID: 8664548]
2. Chow RL, Altmann CR, Lang RA, Hemmati-Brivanlou A. Pax6 induces ectopic eyes in a vertebrate. Development 1999; 126:4213-22. [PMID: 10477290]
3. Carrière C, Plaza S, Caboche J, Dozier C, Bailly M, Martin P, Saule S. Nuclear-Localization Signals, Dna-Binding, and Transactivation Properties of Quail Pax-6 (Pax-Qnr) Isoforms. Cell Growth Differ 1995; 6:1531-40. [PMID: 9019158]
4. Zhang Y, Ferreira HB, Greenstein D, Chisholm A, Emmons SW. Regulated nuclear entry of the C-elegans Pax-6 transcription factor. Mech Dev 1998; 78:179-87. [PMID: 9858725]
5. Mishra R, Gorlov IP, Chao LY, Singh S, Saunders GF. PAX6, paired domain influences sequence recognition by the homeodomain. J Biol Chem 2002; 277:49488-94. [PMID: 12388550]
6. Tripathi R, Mishra R. Interaction of Pax6 with SPARC and p53 in Brain of Mice Indicates Smad3 Dependent Autoregulation. J Mol Neurosci 2010; 41:397-403. [PMID: 20177825]
7. Glaser T, Jepeal L, Edwards JG, Young SR, Favor J, Maas RL. PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects. Nat Genet 1994; 7:463-71. [PMID: 7951315]
8. Schedl A, Ross A, Lee M, Engelkamp D, Rashbass P, VanHeyningen V, Hastie ND. Influence of PAX6 gene dosage on development: Overexpression causes severe eye abnormalities. Cell 1996; 86:71-82. [PMID: 8689689]
9. Kumar JP. Signalling pathways in Drosophila and vertebrate retinal development. Nat Rev Genet 2001; 2:846-57. [PMID: 11715040]
10. Gehring WJ, Ikeo K. Pax 6: mastering eye morphogenesis and eye evolution. Trends Genet 1999; 15:371-7. [PMID: 10461206]
11. Lang RA. Pathways regulating lens induction in the mouse. Int J Dev Biol 2004; 48:783-91. [PMID: 15558471]
12. Honjo Y, Nagineni CN, Larsson J, Nandula SR, Hooks JJ, Chan CC, Karlsson S, Kulkarni AB. Neuron-specific TGF-beta signaling deficiency results in retinal detachment and cataracts in mice. Biochem Biophys Res Commun 2007; 352:418-22. [PMID: 17126294]
13. Liu J, Wilson S, Reh T. BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Dev Biol 2003; 256:34-48. [PMID: 12654290]
14. Trousse F, Esteve P, Bovolenta P. BMP4 mediates apoptotic cell death in the developing chick eye. J Neurosci 2001; 21:1292-301. [PMID: 11160400]
15. Grocott T, Frost V, Maillard M, Johansen T, Wheeler GN, Dawes LJ, Wormstone IM, Chantry A. The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of thePax6 P1 promoter. Nucleic Acids Res 2007; 35:890-901. [PMID: 17251190]
16. Mishima H, Hibino T, Hara H, Murakami J, Otori T. SPARC from corneal epithelial cells modulates collagen contraction by keratocytes. Invest Ophthalmol Vis Sci 1998; 39:2547-53. [PMID: 9856764]
17. Yan Q, Sage EH, Hendrickson AE. SPARC is expressed by ganglion cells and astrocytes in bovine retina. J Histochem Cytochem 1998; 46:3-10. [PMID: 10712100]
18. Magee RM, Hagan S, Hiscott PS, Sheridan CM, Carron JA, McGalliard J, Grierson I. Synthesis of osteonectin by human retinal pigment epithelial cells is modulated by cell density. Invest Ophthalmol Vis Sci 2000; 41:2707-11. [PMID: 10937587]
19. Yan Q, Clark JI, Sage EH. Expression and characterization of SPARC in human lens and in the aqueous and vitreous humors. Exp Eye Res 2000; 71:81-90. [PMID: 10880278]
20. Yan Q, Weaver M, Perdue N, Sage EH. Matricellular protein SPARC is translocated to the nuclei of immortalized murine lens epithelial cells. J Cell Physiol 2005; 203:286-94. [PMID: 15534859]
21. Berryhill BL, Kane B, Stramer BM, Fini ME, Hassell JR. Increased SPARC accumulation during corneal repair. Exp Eye Res 2003; 77:85-92. [PMID: 12823991]
22. Kantorow M, Huang Q, Yang XJ, Sage EH, Magabo KS, Miller KM, Horwitz J. Increased expression of osteonectin/SPARC mRNA and protein in age-related human cataracts and spatial expression in the normal human lens. Mol Vis 2000;6:24-9. [PMID: 10756178]
23. Kantorow M, Horwitz J, Carper D. Up-regulation of osteonectin/SPARC in age-related cataractous human lens epithelia. Mol Vis 1998; 4:17-23. [PMID: 9743541]
24. Gilbert RE, Cox AJ, Kelly DJ, Wilkinson-Berka JL, Sage EH, Jerums G, Cooper ME. Localization of secreted protein acidic and rich in cysteine (SPARC) expression in the rat eye. Connect Tissue Res 1999; 40:295-303. [PMID: 10757117]
25. Gotoh N, Perdue NR, Matsushima H, Sage EH, Yan Q, Clark JI. An in vitro model of posterior capsular opacity: SPARC and TGF-beta2 minimize epithelial-to-mesenchymal transition in lens epithelium. Invest Ophthalmol Vis Sci 2007; 48:4679-87. [PMID: 17898292]
26. Mu Y, Gudey SK, Landström M. Non-Smad signalling Pathways. Cell Tissue Res 2012; 347:11-20. [PMID: 21701805]
27. Attisano L, Wrana JL. Smads as transcriptional co-modulators. Curr Opin Cell Biol 2000; 12:235-43. [PMID: 10712925]
28. Massagué J, Wotton D. Transcriptional control by the TGFbeta/ Smad signaling system. EMBO J 2000; 19:1745-54. [PMID: 10775259]
29. ten Dijke P, Miyazono K, Heldin CH. Signaling inputs converge on nuclear effecters in TGF-beta signaling. Trends Biochem Sci 2000; 25:64-70. [PMID: 10664585]
30. Inman GJ, Nicolas FJ, Hill CS. Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity. Mol Cell 2002; 10:283-94. [PMID: 12191474]
31. Xu L, Alarcon X, Col S, Massague J. Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import. J Biol Chem 2003; 278:42569-77. [PMID: 12917407]