The measurement of the β/α anomer composition within amorphous lactose prepared by spray and freeze drying using a simple 1H-NMR method

Pharmaceutical Research

Volumn 29, Issue 2, 2012, Pages 511-524

  Jawad, Rim ^a   Elleman, Carole ^b   Vermeer, Louic ^a   Drake, Alex F ^a   Woodhead, Brendon ^a   Martin, Gary P ^a   Royall, Paul G ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Reading Scientific Services Ltd   (United Kingdom)

Author keywords

anomer composition; Amorphous; Freeze drying; Lactose; NMR; Spray drying

Indexed keywords

ALDEHYDE; LACTOSE; PROTON; SILICON DIOXIDE; EXCIPIENT;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FREEZE DRYING; NUCLEAR MAGNETIC RESONANCE; OPTICAL ROTATION; POLARIMETER; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SPRAY DRYING; THERMOGRAVIMETRY; X RAY DIFFRACTION; CHEMISTRY; CRYSTALLIZATION; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POWDER DIFFRACTION;

CRYSTALLIZATION; EXCIPIENTS; FREEZE DRYING; LACTOSE; MAGNETIC RESONANCE SPECTROSCOPY; POWDER DIFFRACTION; X-RAY DIFFRACTION;

EID: 84860859015     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0575-6     Document Type: Article

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