Investigation of biodegradable and biocompatible castor oil poly(mannitolcitric-sebacate) polyester as a drug carrier

Current Science

Volumn 102, Issue 1, 2012, Pages 97-104

  Sathiskumar, P S ^a   Chopra, Sunita ^a   Madras, Giridhar ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Biocompatibility; Biodegradable; Castor oil polyesters; Drug delivery

Indexed keywords

EID: 84860847458     PISSN: 00113891     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Edlund, U. and Albertsson, A. C., Degradable polymer microspheres for controlled drug delivery. In Degradable Aliphatic Polyesters, Springer, Berlin, 2002, vol. 157, pp. 67-112.
2. Uhrich, K. E., Cannizzaro, S. M., Langer, R. S. and Shakesheff, K. M., Polymeric systems for controlled drug release. Chem. Rev., 1999, 99, 3181-3198.
3. Brouwers, J. R. B. J., Advanced and controlled drug-delivery systems in clinical disease management. Pharm. World Sci., 1996, 18, 153-162.
4. Zhou, S., Deng, X., Yuan, M. and Li, X., Investigation on preparation and protein release of biodegradable polymer microspheres as drug-delivery system. J. Appl. Polym. Sci., 2002, 84, 778-784.
5. Bai, X.-L., Yang, Y.-Y., Chung, T.-S., Ng, S. and Heller, J., Effect of polymer compositions on the fabrication of poly(ortho-ester) microspheres for controlled release of protein. J. Appl. Polym. Sci., 2001, 80, 1630-1642.
6. Azab, A. K., Kleinstern, J., Doviner, V., Orkin, B., Srebnik, M., Nissan, A. and Rubinstein, A., Prevention of tumor recurrence and distant metastasis formation in a breast cancer mouse model by biodegradable implant of 131 Inorcholesterol. J. Control. Release, 2007, 123, 116-122.
7. Cheung, R., Ying, Y., Rauth, A., Marcon, N. and Yuwu, X., Biodegradable dextran-based microspheres for delivery of anticancer drug mitomycin C. Biomaterials, 2005, 26, 5375-5385.
8. Liu, J., Meisner, D., Kwong, E., Wu, X. Y. and Johnston, M. R., A novel translymphatic drug-delivery system: implantable gelatin sponge impregnated with PLGA-paclitaxel microspheres. Biomaterials, 2007, 28, 3236-3244.
9. Brem, H., Polymers to treat brain tumours. Biomaterials, 1990, 11, 699-701.
10. Sun, Z.-J. et al., The application of poly(glycerol-sebacate) as biodegradable drug carrier. Biomaterials, 2009, 30, 5209-5214.
11. Gunatillake, P. A., Adhikari, R. and Gadegaard, N., Biodegradable synthetic polymers for tissue engineering. Eur. Cells Mater., 2003, 5, 1-16.
12. Diasio, R. B. and Harris, B. E., Clinical pharmacology of 5-fluorouracil. Clin. Pharmacokinet., 1989, 16, 215-237.
13. Heller, J. et al., Use of poly(ortho esters) for the controlled release of 5-fluorouracyl and a LHRH analogue. J. Control. Release, 1987, 6, 217-224.
14. Sathiskumar, P. S. and Madras, G., Synthesis, characterization, degradation of biodegradable castor oil based polyesters. Polym. Degrad. Stabil., 2011, 96, 1695-1704.
15. Katti, D. S., Lakshmi, S., Langer, R. and Laurencin, C. T., Toxicity, biodegradation and elimination of polyanhydrides. Adv. Drug Deliv. Rev., 2002, 54, 933-961.
16. Bruggeman, J. P., de Bruin, B.-J., Bettinger, C. J. and Langer, R., Biodegradable poly(polyol sebacate) polymers. Biomaterials, 2008, 29, 4726-4735.
17. Yang, J., Webb, A. R., Pickerill, S. J., Hageman, G. and Ameer, G. A., Synthesis and evaluation of poly(diol citrate) biodegradable elastomers. Biomaterials, 2006, 27, 1889-1898.
18. Kenawy, E.-R., Abdel-Hay, F., El-Newehy, M. and Ottenbrite, R. M., Effect of pH on the drug release rate from a new polymer- drug conjugate system. Polym. Int., 2008, 57, 85-91.
19. Yeganeh, H. and Hojati-Talemi, P., Preparation and properties of novel biodegradable polyurethane networks based on castor oil and poly(ethylene glycol). Polym. Degrad. Stabil., 2007, 92, 480- 489.
20. Li, X., Deng, X., Yuan, M., Xiong, C., Huang, Z., Zhang, Y. and Jia, W., In vitro degradation and release profiles of poly-DLlactide-poly(ethylene glycol) microspheres with entrapped proteins. J. Appl. Polym. Sci., 2000, 78, 140-148.
21. Freiberg, S. and Zhu, X. X., Polymer microspheres for controlled drug release. Int. J. Pharma., 2004, 282, 1-18.
22. Kim, G. Y., Tyler, B. M., Tupper, M. M., Karp, J. M., Langer, R. S., Brem, H. and Cima, M. J., Resorbable polymer microchips releasing BCNU inhibit tumor growth in the rat 9L flank model. J. Control. Release, 2007, 123, 172-178.
23. Fung, L. K., Shin, M., Tyler, B., Brem, H. and Saltzman, W. M., Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-l-nitrosourea in the rat brain. Pharm. Res., 1996, 13(5), 671-682.
24. Ritger, P. L. and Peppas, N. A., A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. J. Control. Rel., 1987, 5, 37-42.