Gender-specific differences in susceptibility to low-dose methadone-associated QTc prolongation in patients with heroin dependence

Journal of Cardiovascular Electrophysiology

Volumn 23, Issue 5, 2012, Pages 527-533

  Chang, Kuan Cheng ^a,b   Huang, Chieh Liang ^a   Liang, Hsin Yueh ^a   Chang, Shih Sheng ^a   Wang, Yu Chen ^a   Liang, Wen Miin ^b   Lane, Hsien Yuan ^a   Chen, Chu Huang ^b   Stephen Huang, Shoei K ^c  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

gender; heroin dependence; methadone; potassium currents; QT interval

Indexed keywords

METHADONE;

ADULT; ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION COEFFICIENT; CROSS-SECTIONAL STUDY; DISEASE PREDISPOSITION; ELECTROCARDIOGRAPHY; FEMALE; HEROIN DEPENDENCE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; POTASSIUM CURRENT; PRIORITY JOURNAL; QT PROLONGATION; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE;

ACTION POTENTIALS; ADULT; ANALGESICS, OPIOID; CHINA; CROSS-SECTIONAL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HEROIN DEPENDENCE; HUMANS; LINEAR MODELS; LONG QT SYNDROME; LONGITUDINAL STUDIES; MALE; METHADONE; MIDDLE AGED; OPIATE SUBSTITUTION TREATMENT; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; RISK FACTORS; SEX FACTORS; TIME FACTORS;

EID: 84860840896     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2011.02231.x     Document Type: Article

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