Serum ferritin and total units transfused for assessing iron overload in adults with sickle cell disease

British Journal of Haematology

Volumn 157, Issue 5, 2012, Pages 645-647

  Drasar, Emma ^a,b   Vasavda, Nisha ^b   Igbineweka, Norris ^b   Awogbade, Moji ^a   Allman, Marlene ^a   Thein, Swee Lay ^a,b  

^a KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Blood transfusion; Ferritin; Iron loading; Sickle cell disease

Indexed keywords

FERRITIN; IRON CHELATING AGENT;

ADOLESCENT; ADULT; AGED; BLOOD TRANSFUSION; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DRY WEIGHT; FEMALE; FERRITIN BLOOD LEVEL; HUMAN; IRON OVERLOAD; LETTER; LIVER IRON CONCENTRATION; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SICKLE CELL ANEMIA; TOTAL TOP UP UNITS TRANSFUSED;

ANEMIA, SICKLE CELL; BLOOD TRANSFUSION; FERRITINS; HUMANS; IRON OVERLOAD;

EID: 84860836952     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2012.09060.x     Document Type: Letter

References (5)

1. Adamkiewicz, T.V., Abboud, M.R., Paley, C., Olivieri, N., Kirby-Allen, M., Vichinsky, E., Casella, J.F., Alvarez, O.A., Barredo, J.C., Lee, M.T., Iyer, R.V., Kutlar, A., McKie, K.M., McKie, V., Odo, N., Gee, B., Kwiatkowski, J.L., Woods, G.M., Coates, T., Wang, W. & Adams, R.J. (2009) Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury. Blood, 114, 4632-4638.
2. Adams, M.D., Ataga, K.I., Ballard, H., Benjamin, L., Billett, H., Boehme, C., Bridges, K., Castro, O., Charache, S., Covitz, W., Cutter, G.R., Dampier, C.D., DeSimone, J., Earles, A., Eckman, J., Goldberg, M., Jergeson, H.E., Johnson, C., Johnson-Telfair, P.A.C., Joiner, C., Kark, J.D., Koshy, M., Lane, P., Loukopoulos, D., Lubin, B.H., Mandell, M.S.N., Mankad, V., Mann, M., Nagel, R.L., Norcott, K., Ohene-Frempong, K., Orringer, E., Platt, O.S., Ross, S., Shafer, F., Smith, J., Smith-Whitley, K., Steinberg, M.H., Stuart, M., Swerdlow, P., Telfair, J., Townes, T., Treadwell, M., Vichinsky, E., Walters, M., Wang, W., Ware, R., Wethers, D., Whitten, C., Whitten-Shurney, W., Windrow, N., Yamashita, R., Alving, B., Rodgers, G., Chang, H., Peterson, C., Bonds, D., Evans, G., Bodine, D., Drugan, J., Barrow, P. & Brasier, K. (2004) The Management of Sickle Cell Disease. NIH publication No 04-2117. National Institutes of Health, Bethesda, MD, USA.
3. Drasar, E., Igbineweka, N., Vasavda, N., Free, M., Awogbade, M., Allman, M., Mijovic, A. & Thein, S.L. (2011) Blood transfusion usage among adults with sickle cell disease - a single institution experience over ten years. British Journal of Haematology, 152, 766-770.
4. Inati, A., Musallam, K.M., Wood, J.C. & Taher, A.T. (2010) Iron overload indices rise linearly with transfusion rate in patients with sickle cell disease. Blood, 115, 2980-2981; author reply 2981-2982.
5. St Pierre, T.G., Clark, P.R., Chua-anusorn, W., Fleming, A.J., Jeffrey, G.P., Olynyk, J.K., Pootrakul, P., Robins, E. & Lindeman, R. (2005) Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood, 105, 855-861.