Transarterial chemoembolization in very early and early-stage hepatocellular carcinoma patients excluded from curative treatment: A prospective cohort study

European Journal of Radiology

Volumn 81, Issue 6, 2012, Pages 1173-1178

  Bargellini, Irene ^a   Sacco, Rodolfo ^b,c   Bozzi, Elena ^a   Bertini, Marco ^b   Ginanni, Barbara ^a   Romano, Antonio ^b   Cicorelli, Antonio ^a   Tumino, Emanuele ^b   Federici, Graziana ^b   Cioni, Roberto ^a   Metrangolo, Salvatore ^b   Bertoni, Michele ^b   Bresci, Giampaolo ^b   Parisi, Giuseppe ^b   Altomare, Emanuele ^c   Capria, Alfonso ^b   Bartolozzi, Carlo ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

^c UNIVERSITY OF FOGGIA   (Italy)

Author keywords

Chemoembolization; Hepatocellular carcinoma; Interventional radiology; Liver transplantation; Survival

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN;

AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CANCER GROWTH; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; CHEMOEMBOLIZATION; CLINICAL TRIAL; DISEASE SEVERITY; FEMALE; FOLLOW UP; HOSPITAL DISCHARGE; HUMAN; LIVER CELL CARCINOMA; LIVER FAILURE; LIVER FUNCTION; LIVER TOXICITY; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; TREATMENT OUTCOME; TREATMENT RESPONSE;

AGED; CARCINOMA, HEPATOCELLULAR; CHEMOEMBOLIZATION, THERAPEUTIC; CHI-SQUARE DISTRIBUTION; DISEASE PROGRESSION; EPIRUBICIN; ETHIODIZED OIL; FEMALE; HUMANS; LIVER FUNCTION TESTS; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; NEOPLASM RECURRENCE, LOCAL; PATIENT SELECTION; PROSPECTIVE STUDIES; SURVIVAL RATE; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84860776105     PISSN: 0720048X     EISSN: 18727727     Source Type: Journal    
DOI: 10.1016/j.ejrad.2011.03.046     Document Type: Article

References (36)

1. V. Mazzaferro, E. Regalia, and R. Doci Liver transplantation for the treatment of small hepatocellular carcinoma in patients with cirrhosis N Engl J Med 334 1996 693 699
2. J. Bruix, and J.M. Llovet Prognostic prediction and treatment strategy in hepatocellular carcinoma Hepatology 35 2002 519 524
3. J.M. Llovet, A.M. Di Bisceglie, and J. Bruix Design and end-points of clinical trials in hepatocellular carcinoma J Natl Cancer Inst 100 2008 698 711
4. J. Bruix, M. Sherman, and J.M. Llovet EASL Panel of Experts on HCC. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver J Hepatol 35 2001 421 430
5. J. Bruix, and M. Sherman Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma Hepatology 42 2005 1208 1236
6. C.M. Lo, H. Ngan, and W.K. Tso Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma Hepatology 35 2002 1164 1171
7. J.M. Llovet, M.I. Real, and X. Montaña Barcelona Liver Cancer Group. Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial Lancet 359 2002 1734 1739
8. M. Varela, M. Reig, and M.D. Mata Treatment approach of hepatocellular carcinoma in Spain. Analysis of 705 patients from 62 centers Med Clin (Barc) 134 2010 569 576
9. A. Forner, M.E. Reig, C.R. de Lope, and J. Bruix Current strategy for staging and treatment: the BCLC update and future prospects Semin Liver Dis 30 1 2010 61 74
10. D.B. Brown, C.E. Fundakowski, and M. Lisker-Melman Comparison of MELD and Child-Pugh scores to predict survival after chemoembolization for hepatocellular carcinoma J Vasc Interv Radiol 15 2004 1209 1218
11. E.A. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) Eur J Cancer 45 2009 228 247
12. D.B. Brown, J.F. Cardella, and D. Sacks Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy J Vasc Interv Radiol 20 Suppl. 7 2009 S219-S226, e1-10
13. R. Lencioni, and J.M. Llovet Modified RECIST (mRECIST) assessment for hepatocellular carcinoma Semin Liver Dis 30 1 2010 52 60
14. S.H. Kim, W.J. Lee, H.K. Lim, and J.H. Lim Prediction of viable tumor in hepatocellular carcinoma treated with transcatheter arterial chemoembolization: usefulness of attenuation value measurement at quadruple-phase helical computed tomography J Comput Assist Tomogr 31 2007 198 203
15. D.M. Parkin Global cancer statistics in the year 2000 Lancet Oncol 2 2001 533 543
16. H.B. El-Serag, and A.C. Mason Rising incidence of hepatocellular carcinoma in the United States N Engl J Med 340 1999 745 750
17. S.F. Altekruse, K.A. Glynn, and M.E. Reichman Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005 J Clin Oncol 27 2009 1485 1491
18. G.L. Davis, J.E. Albright, S.F. Cook, and D.M. Rosenberg Projecting future complications of chronic hepatitis C in the United States Liver Transpl 9 2003 331 338
19. A.C. Chan, R.T. Poon, K.K. Ng, C.M. Lo, S.T. Fan, and J. Wong Changing paradigm in the management of hepatocellular carcinoma improves the survival benefit of early detection by screening Ann Surg 247 2008 666 673
20. M. Borzio, G. Colloredo, P. Pioltelli, and M. Quagliuolo Gruppo Epatologico Lombardo (GEL). Epidemiology and outcome of hepatocellular carcinoma in Lombardy Dig Liver Dis 39 2007 1011 1017
21. N.N. Massarweh, J.O. Park, and F. Farjah Trends in the utilization and impact of radiofrequency ablation for hepatocellular carcinoma J Am Coll Surg 210 2010 441 448
22. L. Marelli, R. Stigliano, and C. Triantos Transarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies Cardiovasc Intervent Radiol 30 1 2007 6 25
23. K. Takayasu, S. Arii, and I. Ikai Liver Cancer Study Group of Japan. Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients Gastroenterology 131 2006 461 469
24. S.Y. Song, J.W. Chung, and J.K. Han Liver abscess after transcatheter oily chemoembolization for hepatic tumors: incidence, predisposing factors, and clinical outcome J Vasc Interv Radiol 12 2001 313 320
25. J.F. Geschwind, S. Kaushik, D.E. Ramsey, M.A. Choti, E.K. Fishman, and H. Kobeiter Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses after chemoembolization treatment of liver tumors J Vasc Interv Radiol 13 2002 1163 1166
26. K. Malagari, K. Chatzimichael, and E. Alexopoulou Transarterial chemoembolization of unresectable hepatocellular carcinoma with drug eluting beads: results of an open-label study of 62 patients Cardiovasc Intervent Radiol 31 2008 269 280
27. M. Varela, M.I. Real, and M. Burrel Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics J Hepatol 46 2007 474 481
28. J. Lammer, K. Malagari, and T. Vogl On behalf of the PRECISION V Investigators Prospective Randomized Study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V Study Cardiovasc Intervent Radiol 33 2010 41 52
29. R. Sacco, M. Bertini, and P. Petruzzi Clinical impact of selective transarterial chemoembolization on hepatocellular carcinoma: a cohort study World J Gastroenterol 15 2009 1843 1848
30. A. Nicolini, L. Martinetti, S. Crespi, M. Maggioni, and A. Sangiovanni Transarterial chemoembolization with epirubicin-eluting beads versus transarterial embolization before liver transplantation for hepatocellular carcinoma J Vasc Interv Radiol 21 2010 327 332
31. D.K. Reyes, J.A. Vossen, and I.R. Kamel Single-center phase II trial of transarterial chemoembolization with drug-eluting beads for patients with unresectable hepatocellular carcinoma: initial experience in the United States Cancer J 15 2009 526 532
32. C. Cha, Y. Fong, W.R. Jarnagin, L.H. Blumgart, and R.P. DeMatteo Predictors and patterns of recurrence after resection of hepatocellular carcinoma J Am Coll Surg 197 2003 753 758
33. J.M. Llovet, and M. Beaugrand Hepatocellular carcinoma: present status and future prospects J Hepatol 38 Suppl. 1 2003 S136 S149
34. R. Lencioni, D. Cioni, and L. Crocetti Early-stage hepatocellular carcinoma in patients with cirrhosis: long-term results of percutaneous image-guided radiofrequency ablation Radiology 234 3 2005 961 967
35. B. Yang, J. Zou, and J. Xia Risk factors for recurrence of small hepatocellular carcinoma after long-term follow-up of percutaneous radiofrequency ablation Eur J Radiol 2010 [Epub ahead of print]
36. M.F. Yuen, A.O. Chan, and B.C. Wong Transarterial chemoembolization for inoperable, early stage hepatocellular carcinoma in patients with Child-Pugh grade A and B: results of a comparative study in 96 Chinese patients Am J Gastroenterol 98 5 2003 1181 1185