Inhibitors of p38 and ERK1/2 MAPkinase and hydrogen sulphide block constitutive and IL-1β-induced IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2

Rheumatology International

Volumn 32, Issue 3, 2012, Pages 729-736

  Kloesch, B ^a   Liszt, M ^a   Steiner, G ^b   Broll J ^a  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

H 2S; Interleukin 6; Interleukin 8; Mitogen activated protein kinases

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HYDROGEN SULFIDE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NATRIUM HYDROGEN SULFIDE; SODIUM; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; NITRILE; PYRIDINE DERIVATIVE;

ARTICLE; CARTILAGE CELL; DRUG ACTIVITY; DRUG EFFECT; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; CELL LINE; DRUG ANTAGONISM; GENE EXPRESSION; GENETICS; METABOLISM;

BUTADIENES; CELL LINE; CHONDROCYTES; DRUG ANTAGONISM; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; HYDROGEN SULFIDE; IMIDAZOLES; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES;

EID: 84860756043     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-010-1682-0     Document Type: Article

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