Comparative study between trimetazidine and ice slush hypothermia in protection against renal ischemia/reperfusion injury in a porcine model

International Braz J Urol

Volumn 37, Issue 5, 2011, Pages 649-656

  Abreu, Leonardo de Albuquerque dos Santos ^a   Kawano, Paulo Roberto ^b   Yamamoto, Hamilto ^b   Damião, Ronaldo ^a   Fugita, Oscar Eduardo Hidetoshi ^b  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Hypothermia; Ischemia; Kidney; Reperfusion injury; Trimetazine

Indexed keywords

ICE; TRIMETAZIDINE; VASODILATOR AGENT;

ANIMAL; ARTICLE; COLD ISCHEMIA; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; INDUCED HYPOTHERMIA; ISCHEMIC PRECONDITIONING; KIDNEY; METHODOLOGY; PATHOLOGY; REPERFUSION INJURY; SWINE; VASCULARIZATION;

ANIMALS; COLD ISCHEMIA; DISEASE MODELS, ANIMAL; HYPOTHERMIA, INDUCED; ICE; ISCHEMIC PRECONDITIONING; KIDNEY; REPERFUSION INJURY; SUS SCROFA; TRIMETAZIDINE; VASODILATOR AGENTS;

EID: 84860753470     PISSN: 16775538     EISSN: 16776119     Source Type: Journal    
DOI: 10.1590/S1677-55382011000500013     Document Type: Article

References (28)

1. Thompson RH, Frank I, Lohse CM, Saad IR, Fergany A, Zincke H, et al.: The impact of ischemia time during open nephron sparing surgery on solitary kidneys: a multi-institutional study. J Urol. 2007; 177: 471-6.
2. Foyil KV, Ames CD, Ferguson GG, Weld KJ, Figenshau RS, Venkatesh R, et al.: Longterm changes in creatinine clearance after laparoscopic renal surgery. J Am Coll Surg. 2008; 206: 511-5.
3. Di Sole F: Adenosine and renal tubular function. Curr Opin Nephrol Hypertens. 2008; 17: 399-407.
4. Wickham JE, Fernando AR, Hendry WF, Whitfield HN, Fitzpatrick JM: Intravenous inosine for ischaemic renal surgery. Br J Urol. 1979; 51: 437-9.
5. Hansson R, Johansson S, Jonsson O, Pettersson S, Scherstén T, Waldenström J: Kidney protection by pretreatment with free radical scavengers and allopurinol: renal function at recirculation after warm ischaemia in rabbits. Clin Sci (Lond). 1986; 71: 245-51.
6. Yang CW, Ahn HJ, Han HJ, Kim WY, Li C, Shin MJ, et al.: Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/ reperfusion injury in rat kidney. Transplantation. 2001; 72: 1753-9.
7. Takahira R, Yonemura K, Fujise Y, Hishida A: Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl. Free Radic Biol Med. 2001; 31: 809-15.
8. Dobashi K, Singh I, Orak JK, Asayama K, Singh AK: Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemiareperfusion injury in rat kidney. Mol Cell Biochem. 2002; 240: 9-17.
9. McAnulty JF, Huang XQ: The effects of administering quinacrine during ultraprofound hypothermia on warm ischemic kidney cortex tissue. J Pharmacol Exp Ther. 1996; 277: 691-9.
10. Jayachandran S, Mooppan MM, Chou SY, Kim H: Effects of chlorpromazine on ischemic rat kidney: a functional and ultrastructural study. Urology. 1985; 25: 386-90.
11. Unal D, Yeni E, Erel O, Bitiren M, Vural H: Antioxidative effects of exogenous nitric oxide versus antioxidant vitamins on renal ischemia reperfusion injury. Urol Res. 2002; 30: 190-4.
12. Jayle C, Favreau F, Zhang K, Doucet C, Goujon JM, Hebrard W, et al.: Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model. Am J Physiol Renal Physiol. 2007; 292: F1082-93.
13. Mathur VK, Ramsey EW: Comparison of methods for preservation of renal function during ischemic renal surgery. J Urol. 1983; 129: 163-5.
14. Stanley WC, Lopaschuk GD, Hall JL, McCormack JG: Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions. Cardiovasc Res. 1997; 33: 243-57.
15. Sulikowski T, Domanski L, Ciechanowski K, Adler G, Pawlik A, Safranow K, et al.: Effect of trimetazidine on xanthine oxidoreductase expression in rat kidney with ischemia--reperfusion injury. Arch Med Res. 2008; 39: 459-62.
16. Cau J, Favreau F, Tillement JP, Lerman LO, Hauet T, Goujon JM: Trimetazidine reduces early and longterm effects of experimental renal warm ischemia: a dose effect study. J Vasc Surg. 2008; 47: 852-860.
17. Jacobsson L: A method for the calculation of renal clearance based on a single plasma sample. Clin Physiol. 1983; 3: 297-305.
18. Shihabi ZK, Thompson EN, Constantinescu M S: Iohexol determination by direct injection of serum on the HPLC column. J. Liq. Chromatogr. 1993; 16: 1289-96.
19. Thompson RH, Leibovich BC, Lohse CM, Zincke H, Blute ML: Complications of contemporary open nephron sparing surgery: a single institution experience. J Urol. 2005; 174: 855-8.
20. Novick AC: Renal hypothermia: in vivo and ex vivo. Urol Clin North Am. 1983; 10: 637-44.
21. Ward JP: Determination of the Optimum temperature for regional renal hypothermia during temporary renal ischaemia. Br J Urol. 1975; 47: 17-24.
22. Laven BA, Orvieto MA, Chuang MS, Ritch CR, Murray P, Harland RC, et al.: Renal tolerance to prolonged warm ischemia time in a laparoscopic versus open surgery porcine model. J Urol. 2004; 172: 2471-4.
23. Baldwin DD, Maynes LJ, Berger KA, Desai PJ, Zuppan CW, Zimmerman GJ, et al.: Laparoscopic warm renal ischemia in the solitary porcine kidney model. Urology. 2004; 64: 592-7.
24. Orvieto MA, Tolhurst SR, Chuang MS, Lyon MB, Ritch CR, Rapp DE, et al.: Defining maximal renal tolerance to warm ischemia in porcine laparoscopic and open surgery model. Urology. 2005; 66: 1111-5.
25. Schoeppler GM, Klippstein E, Hell J, Häcker A, Trojan L, Alken P, et al.: Prolonged cold ischemia time for laparoscopic partial nephrectomy with a new cooling material: Freka-Gelice--a comparison of four cooling methods. J Endourol. 2010; 24: 1151-4.
26. Guerra R, Leonardi EP, Otsuka RA, Quitzan J, Kawano PR, Yamamoto HA, et al.: Cold renal ischemia: comparison of efficacy between two techniques of cooling, in a swine model. J Endourol. 2010; 24: 445-9.
27. Hauet T, Mothes D, Goujon JM, Caritez JC, Carretier M, le Moyec L, et al.: Trimetazidine prevents renal injury in the isolated perfused pig kidney exposed to prolonged cold ischemia. Transplantation. 1997; 64: 1082-6.
28. Hauet T, Baumert H, Mothes D, Germonville T, Caritez JC, Carretier M, et al.: Lipid peroxidation after cold storage and normothermic reperfusion: the effect of trimetazidine. Transpl Int. 1998; 11(Suppl 1): S408-9.