Fanconi's syndrome and nephrogenic diabetes insipidus in an adult treated with ifosfamide

Pharmacotherapy

Volumn 32, Issue 1, 2012, Pages

  Ingemi, Amanda I ^a   Bota, Vasile M ^b,c   Peguero, Anyeri ^b,c   Charpentier, Margaret ^d  

^a HENRY FORD HOSPITAL   (United States)

^b ROGER WILLIAMS MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Adverse event; Diabetes insipidus; Fanconi's syndrome; Ifosfamide

Indexed keywords

AMILORIDE; DOXORUBICIN; IFOSFAMIDE;

ABNORMAL LABORATORY RESULT; ADULT; ANOREXIA; ARTICLE; CASE REPORT; DISEASE ASSOCIATION; FANCONI RENOTUBULAR SYNDROME; FATIGUE; FEBRILE NEUTROPENIA; FEVER; HUMAN; LEUKOCYTE COUNT; LUNG METASTASIS; MALE; MEDICAL HISTORY; METASTASIS RESECTION; MULTIPLE CYCLE TREATMENT; NEPHROGENIC DIABETES INSIPIDUS; NEPHROTOXICITY; PATIENT MONITORING; POLYDIPSIA; POLYURIA; SARCOMA;

DIABETES INSIPIDUS, NEPHROGENIC; DIAGNOSIS, DIFFERENTIAL; FANCONI SYNDROME; HUMANS; IFOSFAMIDE; MALE; MIDDLE AGED; TREATMENT OUTCOME;

EID: 84860741020     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1002/PHAR.1013     Document Type: Article

References (12)

1. Hanly L, Chen N, Rieder M, Koren G. Ifosfamide nephrotoxicity in children: a mechanistic base for pharmacological prevention. Expert Opin Drug Saf 2009;8:155-68.
2. Kintzel PE. Anticancer drug-induced kidney disorders. Drug Saf 2001;24:29-30.
3. Chen N, Aleksa K, Woodland C, Rieder M, Koren G. The effect of N-acetylcysteine on ifosfamide-induced nephrotoxicity: in vitro studies in renal tubular cells. Transl Res 2007;150:51-7. (Pubitemid 46935594)
4. Rossi R, Godde A, Kleinebrand A, Rath B, Jurgens H. Concentrating capacity in ifosfamide-induced severe renal dysfunction. Ren Fail 1995;17:551-7.
5. Yaseen Z, Michoudet C, Baverel G, Dubourg L. Mechanisms of the ifosfamide-induced inhibition of endocytosis in the rat proximal kidney tubule. Arch Toxicol 2008;82:607-14.
6. Negro A, Regolisti G, Perazzoli F, Davoli S, Sani C, Rossi E. Ifosfamide-induced renal Fanconi syndrome with associated nephrogenic diabetes insipidus in an adult patient. Nephrol Dial Transplant 1998;13:1547-9. (Pubitemid 28254336)
7. Ciarimboli G, Holle SK, Vollenbrocker B, et al. New clues for nephrotoxicity induced by ifosfamide preferential renal uptake via the human organic cation transporter 2. Mol Pharm 2011;8:270-9.
8. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45. (Pubitemid 12149145)
9. Garcia AA. Ifosfamide-induced Fanconi syndrome. Ann Pharmacother 1995;29:590-1.
10. Loffing J. Paradoxical antidiuretic effect of thiazides in diabetes insipidus: another piece in the puzzle. J Am Soc Nephrol 2004;15:2948-50. (Pubitemid 41103404)
11. Chen N, Aleksa K, Woodland C, et al. N-acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats. Br J Pharmacol 2008;153:1364-72. (Pubitemid 351481517)
12. Skinner R, Parry A, Price L, et al. Glomerular toxicity persists 10 years after ifosfamide treatment in childhood and is not predictable by age or dose. Pediatr Blood Cancer 2010;54:983-9.