Genotyping of β-globin gene mutations in single lymphocytes: A preliminary study for preimplantation genetic diagnosis of monogenic disorders

Hemoglobin

Volumn 36, Issue 3, 2012, Pages 230-243

  Durmaz, Burak ^a   Ozkinay, Ferda ^a   Onay, Huseyin ^a   Karaca, Emin ^a   Aydinok, Yesim ^a   Tavmergen, Erol ^a   Vrettou, Christina ^b   Traeger Synodinos, Jan ^b   Kanavakis, Emmanuel ^b  

^a EGE UNIVERSITY   (Turkey)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Globin gene; Real time polymerase chain reaction (PCR); Single cell polymerase chain reaction (PCR); Thalassemia

Indexed keywords

BETA GLOBIN;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HEMOGLOBINOPATHY; HETEROZYGOTE; HUMAN; HUMAN TISSUE; INFANT; LYMPHOCYTE; MALE; MICROSATELLITE MARKER; MONOGENIC DISORDER; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; TURKEY (REPUBLIC);

ADOLESCENT; ADULT; ALLELES; BETA-GLOBINS; BETA-THALASSEMIA; CHILD; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENOTYPE; GENOTYPING TECHNIQUES; HUMANS; INFANT; LYMPHOCYTES; MALE; MICROSATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREIMPLANTATION DIAGNOSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SINGLE-CELL ANALYSIS; TURKEY;

EID: 84860738512     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630269.2012.675891     Document Type: Article

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