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Volumn 27, Issue 6, 2012, Pages 1849-1856

Role of systemic chemotherapy in the management of resected or resectable colorectal liver metastases: A systematic review and meta-analysis of randomized controlled trials

Author keywords

Colorectal cancer; Liver metastases; Meta analysis; Resectable; Resected; Systematic review; Systemic chemotherapy

Indexed keywords

FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN;

EID: 84860721647     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1740     Document Type: Article
Times cited : (59)

References (65)
  • 3
    • 35348972526 scopus 로고    scopus 로고
    • Epidemiology, disease progression, and economic burden of colorectal cancer
    • Benson AB III: Epidemiology, disease progression, and economic burden of colorectal cancer. J Manag Care Pharm 13 (6 Suppl C): S5-S18, 2007.
    • (2007) J Manag Care Pharm , vol.13 , Issue.6 SUPPL. C
    • Benson III, A.B.1
  • 4
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt JA and Mayer RJ: Systemic therapy for colorectal cancer. N Engl J Med 352: 476-487, 2005.
    • (2005) N Engl J Med , vol.352 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 5
    • 34447554584 scopus 로고    scopus 로고
    • Colorectal cancer: What has changed in diagnosis and treatment over the last 50 years?
    • Gennari L, Russo A and Rossetti C: Colorectal cancer: what has changed in diagnosis and treatment over the last 50 years? Tumori 93: 235-241, 2007. (Pubitemid 47080007)
    • (2007) Tumori , vol.93 , Issue.3 , pp. 235-241
    • Gennari, L.1    Russo, A.2    Rossetti, C.3
  • 6
    • 34548043520 scopus 로고    scopus 로고
    • Adjuvant therapies for colorectal cancer
    • Kosmider S and Lipton L: Adjuvant therapies for colorectal cancer. World J Gastroenterol 13: 3799-3805, 2007. (Pubitemid 47277226)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.28 , pp. 3799-3805
    • Kosmider, S.1    Lipton, L.2
  • 8
    • 6044226542 scopus 로고    scopus 로고
    • German Rectal Cancer Study Group: Preoperative versus postoperative chemoradiotherapy for rectal cancer
    • Sauer R, Becker H, Hohenberger W, et al: German Rectal Cancer Study Group: Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351: 1731-1740, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1731-1740
    • Sauer, R.1    Becker, H.2    Hohenberger, W.3
  • 9
    • 40449103322 scopus 로고    scopus 로고
    • Advanced colorectal cancer: ESMO clinical recommendations for diagnosis,treatment and follow-up
    • ESMO Guidelines Working Group
    • ESMO Guidelines Working Group, Van Cutsem EJ: Advanced colorectal cancer: ESMO clinical recommendations for diagnosis,treatment and follow-up. Ann Oncol 18 (Suppl 2): ii25-6, 2007.
    • (2007) Ann Oncol , vol.18 , Issue.SUPPL. 2
    • Van Cutsem, E.J.1
  • 10
    • 6944230093 scopus 로고    scopus 로고
    • Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging
    • DOI 10.1093/jnci/djh275
    • O'Connell JB, Maggard MA and Ko CY: Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst 96: 1420-1425, 2004. (Pubitemid 39429665)
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.19 , pp. 1420-1425
    • O'Connell, J.B.1    Maggard, M.A.2    Ko, C.Y.3
  • 11
    • 0021282270 scopus 로고
    • The natural history of hepatic metastases from colorectal cancer. A comparison with resective treatment
    • Wagner JS, Adson MA, Van Heerden JA, Adson MH and Ilstrup DM: The natural history of hepatic metastases from colorectal cancer. A comparison with resective treatment. Ann Surg 199: 502-508, 1984. (Pubitemid 14105105)
    • (1984) Annals of Surgery , vol.199 , Issue.5 , pp. 502-508
    • Wagner, J.S.1    Adson, M.A.2    Van Heerden, J.A.3
  • 12
    • 34250021354 scopus 로고    scopus 로고
    • Epidemiology of colorectal liver metastases
    • DOI 10.1016/j.suronc.2007.04.008, PII S0960740407000242, Metastatic Colorectal Cancer
    • McMillan DC and McArdle CS: Epidemiology of colorectal liver metastases. Surg Oncol 16: 3-5, 2007. (Pubitemid 46887664)
    • (2007) Surgical Oncology , vol.16 , Issue.1 , pp. 3-5
    • McMillan, D.C.1    McArdle, C.S.2
  • 13
    • 35348833118 scopus 로고    scopus 로고
    • WITHDRAWN: Resection versus no intervention or other surgical interventions for colorectal cancer liver metastases
    • CDUO6039
    • Al-Asfoor A and Fedorowicz Z: WITHDRAWN: Resection versus no intervention or other surgical interventions for colorectal cancer liver metastases. Cochrane Database Syst Rev 17: CDUO6039, 2007.
    • (2007) Cochrane Database Syst Rev , vol.17
    • Al-Asfoor, A.1    Fedorowicz, Z.2
  • 14
    • 34547141354 scopus 로고    scopus 로고
    • Clinical, biological, and molecular aspects of metastasis in colorectal cancer
    • Stein U and Schlag PM: Clinical, biological, and molecular aspects of metastasis in colorectal cancer. Recent Results Cancer Res 176: 61-80, 2007.
    • (2007) Recent Results Cancer Res , vol.176 , pp. 61-80
    • Stein, U.1    Schlag, P.M.2
  • 15
    • 33644638369 scopus 로고    scopus 로고
    • Resection of colorectal liver metastases: Current perspectives
    • McLoughlin JM, Jensen EH and Malafa M: Resection of colorectal liver metastases: current perspectives. Cancer Control 13: 32-41, 2006. (Pubitemid 43327552)
    • (2006) Cancer Control , vol.13 , Issue.1 , pp. 32-41
    • McLoughlin, J.M.1    Jensen, E.H.2    Malafa, M.3
  • 16
    • 0023161984 scopus 로고
    • Resection of liver metastasis - When is it worthwile?
    • Adson MA: Resection of liver metastases: When is it worthwhile? World J Surg 11: 511-520, 1987. (Pubitemid 17137106)
    • (1987) World Journal of Surgery , vol.11 , Issue.4 , pp. 511-520
    • Adson, M.A.1
  • 18
    • 0023861077 scopus 로고
    • Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection-registry of hepatic metastases
    • Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of indications for resection-registry of hepatic metastases. Surgery 103: 278-288, 1988.
    • (1988) Surgery , vol.103 , pp. 278-288
  • 19
    • 0028308472 scopus 로고
    • Factors influencing the natural history of colorectal liver metastases
    • DOI 10.1016/S0140-6736(94)92529-1
    • Stangl R, Altendorf-Hofman A, Charnley RM, et al: Factors influencing the natural history of colorectal liver metastases. Lancet 343: 1405-1410, 1994. (Pubitemid 24167517)
    • (1994) Lancet , vol.343 , Issue.8910 , pp. 1405-1410
    • Stangl, R.1    Altendorf-Hofmann, A.2    Charnley, R.M.3    Scheele, J.4
  • 22
    • 0035346978 scopus 로고    scopus 로고
    • Resektion colorectaler Lebermetastasen: Welche Prognosefaktoren bestimmen die Patientenselektion?
    • DOI 10.1007/s001040051345
    • Scheele J, Altendorf-Hofmann A, Grube T, et al: Resection of colorectal liver metastases: what prognostic factors determine patient selection? Chirurg 72: 547-560, 2001 (In German). (Pubitemid 33678653)
    • (2001) Chirurg , vol.72 , Issue.5 , pp. 547-560
    • Scheele, J.1    Altendorf-Hofmann, A.2    Grube, T.3    Hohenberger, W.4    Stangl, R.5    Schmidt, K.6
  • 23
    • 38849175589 scopus 로고    scopus 로고
    • Expanding criteria for resectability of colorectal liver metastases
    • DOI 10.1634/theoncologist.2007-0142
    • Pawlik TM, Schulick RD and Choti MA: Expanding criteria for resectability of colorectal liver metastases. Oncologist 13: 51-64, 2008. (Pubitemid 351206696)
    • (2008) Oncologist , vol.13 , Issue.1 , pp. 51-64
    • Pawlik, T.M.1    Schulick, R.D.2    Choti, M.A.3
  • 25
    • 27244450852 scopus 로고    scopus 로고
    • OncoSurge: A strategy for improving resectability with curative intent in metastatic colorectal cancer
    • Poston GJ, Adam R, Alberts S, et al: OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. J Clin Oncol 23: 7125-7134, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 7125-7134
    • Poston, G.J.1    Adam, R.2    Alberts, S.3
  • 26
    • 0024390441 scopus 로고
    • Resection of hepatic metastases from colorectal cancer. Biologic perspective
    • Steele G Jr and Ravikumar TS: Resection of hepatic metastases from colorectal cancer. Biologic perspective. Ann Surg 210: 127-138, 1989.
    • (1989) Ann Surg , vol.210 , pp. 127-138
    • Steele Jr., G.1    Ravikumar, T.S.2
  • 28
    • 77952994052 scopus 로고    scopus 로고
    • Metastatic colorectal cancer: From improved survival to potential cure
    • Gallagher DJ and Kemeny N: Metastatic colorectal cancer: from improved survival to potential cure. Oncology 78: 237-248, 2010.
    • (2010) Oncology , vol.78 , pp. 237-248
    • Gallagher, D.J.1    Kemeny, N.2
  • 29
    • 0023156451 scopus 로고
    • Patterns of failure following surgical resection of colorectal cancer liver metastases. Rationale for a multimodal approach
    • Bozzetti F, Doci R, Bignami P, Morabito A and Gennari L: Patterns of failure following surgical resection of colorectal cancer liver metastases: rationale for a multimodal approach. Ann Surg 205: 264-270, 1987. (Pubitemid 17037049)
    • (1987) Annals of Surgery , vol.205 , Issue.3 , pp. 264-270
    • Bozzetti, F.1    Doci, R.2    Bignami, P.3
  • 30
    • 0345505228 scopus 로고    scopus 로고
    • Patterns of failure following curative resection of colorectal liver metastases
    • DOI 10.1053/ejso.2002.1421
    • Topal B, Kaufman L, Aerts R and Penninckx F: Patterns of failure following curative resection of colorectal liver metastases. Eur J Surg Oncol 29: 248-253, 2003. (Pubitemid 36395560)
    • (2003) European Journal of Surgical Oncology , vol.29 , Issue.3 , pp. 248-253
    • Topal, B.1    Kaufman, L.2    Aerts, R.3    Penninckx, F.4
  • 32
    • 0029794696 scopus 로고    scopus 로고
    • Resection of non-resectable liver metastases from colorectal cancer after neoadjuvant chemotherapy
    • Bismuth H, Adam R, Levi F, et al: Resection of non-resectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg 224: 509-520, 1996.
    • (1996) Ann Surg , vol.224 , pp. 509-520
    • Bismuth, H.1    Adam, R.2    Levi, F.3
  • 35
    • 4644320061 scopus 로고    scopus 로고
    • Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: A model to predict long-term survival
    • Adam R, Delvart V, Pascal G, et al: Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: A model to predict long-term survival. Ann Surg 240: 644-657, 2004.
    • (2004) Ann Surg , vol.240 , pp. 644-657
    • Adam, R.1    Delvart, V.2    Pascal, G.3
  • 36
    • 35348905517 scopus 로고    scopus 로고
    • Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemotherapy for unresectable liver metastases
    • DOI 10.1038/sj.bjc.6603988, PII 6603988
    • Pozzo C, Basso M, Quirino M, et al: Long-term follow-up of colorectal cancer (CRC) patients treated with neoadjuvant chemotherapy with Irinotecan and fluorouracil plus folinic acid (5-FU/FA) for unresectable liver metastases. Br J Cancer 97: 1035-1039, 2007. (Pubitemid 47587006)
    • (2007) British Journal of Cancer , vol.97 , Issue.8 , pp. 1035-1039
    • Barone, C.1    Nuzzo, G.2    Cassano, A.3    Basso, M.4    Schinzari, G.5    Giuliante, F.6    D'Argento, E.7    Trigila, N.8    Astone, A.9    Pozzo, C.10
  • 37
    • 33644819672 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: A North Central Cancer Treatment Group phase II study
    • Alberts SR, Horvath WL, Sternfeld WC, et al: Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study. J Clin Oncol 23: 9243-9249, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 9243-9249
    • Alberts, S.R.1    Horvath, W.L.2    Sternfeld, W.C.3
  • 38
    • 85100415918 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2
    • (updated September 2009). Available from
    • Higgins JPT and Green S (eds): Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009. Available from: www.mrc-bsu.cam.ac.uk/cochrane/handbook502.
    • (2009) The Cochrane Collaboration
    • Higgins, J.P.T.1    Green, S.2
  • 39
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB and Mazumdar M: Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101, 1994.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 40
    • 0001910889 scopus 로고    scopus 로고
    • Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis
    • Egger M, Smith GD and Altman DG (eds). 2nd edition. BMJ Publication Group, London
    • Deeks, JJ, Altman DG and Bradburn MJ: Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Systematic Reviews in Health Care: Meta-Analysis in Context. Egger M, Smith GD and Altman DG (eds). 2nd edition. BMJ Publication Group, London, 2001.
    • (2001) Systematic Reviews in Health Care: Meta-Analysis in Context
    • Deeks, J.J.1    Altman, D.G.2    Bradburn, M.J.3
  • 42
    • 13144307188 scopus 로고    scopus 로고
    • Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma
    • Bathe OF, Dowden S, Sutherland F, et al: Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma. BMC Cancer 4: 32, 2004.
    • (2004) BMC Cancer , vol.4 , pp. 32
    • Bathe, O.F.1    Dowden, S.2    Sutherland, F.3
  • 46
    • 76049109203 scopus 로고    scopus 로고
    • Neoadjuvant treatment with weekly high-dose 5-fluorouracil as a 24h-infusion, folinic acid and biweekly oxaliplatin in patients with primary resectable liver metastases of colorectal cancer: Long-term results of a phase II trial
    • Boxberger F, Albrecht H, Konturek PC, et al: Neoadjuvant treatment with weekly high-dose 5-fluorouracil as a 24h-infusion, folinic acid and biweekly oxaliplatin in patients with primary resectable liver metastases of colorectal cancer: long-term results of a phase II trial. Med Sci Monit 16: CR49-CR55, 2010.
    • (2010) Med Sci Monit , vol.16
    • Boxberger, F.1    Albrecht, H.2    Konturek, P.C.3
  • 47
    • 67649780943 scopus 로고    scopus 로고
    • A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases
    • Bathe OF, Ernst S, Sutherland FR, et al: A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases. BMC Cancer 9: 156, 2009.
    • (2009) BMC Cancer , vol.9 , pp. 156
    • Bathe, O.F.1    Ernst, S.2    Sutherland, F.R.3
  • 48
    • 67349166959 scopus 로고    scopus 로고
    • Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy, combined with surgery for resectable colorectal liver metastases?
    • Lubezky N, Geva R, Shmueli E, Nakache R, Klausner JM, Figer A and Ben-Haim M: Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy, combined with surgery for resectable colorectal liver metastases? World J Surg 33: 1028-1034, 2009.
    • (2009) World J Surg , vol.33 , pp. 1028-1034
    • Lubezky, N.1    Geva, R.2    Shmueli, E.3    Nakache, R.4    Klausner, J.M.5    Figer, A.6    Ben-Haim, M.7
  • 49
    • 70449105423 scopus 로고    scopus 로고
    • A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer
    • Ychou M, Hohenberger W, Thezenas S, et al: A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer. Ann Oncol 20: 1964-1970, 2009.
    • (2009) Ann Oncol , vol.20 , pp. 1964-1970
    • Ychou, M.1    Hohenberger, W.2    Thezenas, S.3
  • 50
    • 54449087716 scopus 로고    scopus 로고
    • Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: A pooled analysis of two randomized trials
    • Mitry E, Fields AL, Bleiberg H, et al: Adjuvant chemotherapy after potentially curative resection of metastases from colorectal cancer: a pooled analysis of two randomized trials. J Clin Oncol 26: 4906-4911, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 4906-4911
    • Mitry, E.1    Fields, A.L.2    Bleiberg, H.3
  • 51
    • 68949216600 scopus 로고    scopus 로고
    • Systemic or hepatic arterial chemotherapy is useful after curative resection of liver metastases from colorectal cancer. A meta-analysis of randomized controlled trials
    • Uzzan B, Mariani P, Nicolas P, Perret, G Morere J and des Guetz G: Systemic or hepatic arterial chemotherapy is useful after curative resection of liver metastases from colorectal cancer. A meta-analysis of randomized controlled trials. J Clin Oncol 26 (Suppl): 4077, 2008.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL. , pp. 4077
    • Uzzan, B.1    Mariani, P.2    Nicolas, P.3    Perret, G.4    Morere, J.5    Des Guetz, G.6
  • 52
    • 0345455373 scopus 로고    scopus 로고
    • Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): Results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial
    • Langer B, Bleiberg H, Labianca R, Shepherd L, et al: Fluorouracil (FU) plus l-leucovorin (l-LV) versus observation after potentially curative resection of liver or lung metastases from colorectal cancer (CRC): results of the ENG (EORTC/NCIC CTG/GIVIO) randomized trial. Proc Am Soc Clin Oncol 21: 592, 2002.
    • (2002) Proc Am Soc Clin Oncol , vol.21 , pp. 592
    • Langer, B.1    Bleiberg, H.2    Labianca, R.3    Shepherd, L.4
  • 53
    • 33044488863 scopus 로고    scopus 로고
    • Observation versus postoperative chemotherapy after resection of liver metastases in patients with advanced colorectal cancer
    • Lopez-Ladron A, Salvador J, Bernabe R, et al: Observation versus postoperative chemotherapy after resection of liver metastases in patients with advanced colorectal cancer. Proc Am Soc Clin Oncol 22: 1497, 2003.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 1497
    • Lopez-Ladron, A.1    Salvador, J.2    Bernabe, R.3
  • 55
    • 40749149728 scopus 로고    scopus 로고
    • Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): A randomised controlled trial
    • EORTC Gastro-Intestinal Tract Cancer Group, Cancer Research UK, Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), Australasian Gastro-Intestinal Trials Group (AGITG), Fédération Francophone de Cancérologie Digestive (FFCD)
    • Nordlinger B, Sorbye H, Glimelius B, et al; EORTC Gastro-Intestinal Tract Cancer Group, Cancer Research UK, Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO), Australasian Gastro-Intestinal Trials Group (AGITG), Fédération Francophone de Cancérologie Digestive (FFCD): Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 371: 1007-1016, 2008.
    • (2008) Lancet , vol.371 , pp. 1007-1016
    • Nordlinger, B.1    Sorbye, H.2    Glimelius, B.3
  • 57
    • 35649022759 scopus 로고    scopus 로고
    • Surrogate end points for median overall survival in metastatic colorectal cancer: Literature-based analysis from 39 randomized controlled trials of first-line chemotherapy
    • DOI 10.1200/JCO.2006.08.1935
    • Tang PA, Bentzen SM, Chen EX and Siu LL: Surrogate end points for median overall survival in metastatic colorectal cancer: literature-based analysis from 39 randomized controlled trials of first-line chemotherapy. J Clin Oncol 25: 4562-4568, 2007. (Pubitemid 350035313)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.29 , pp. 4562-4568
    • Tang, P.A.1    Bentzen, S.M.2    Chen, E.X.3    Siu, L.L.4
  • 60
    • 63449116518 scopus 로고    scopus 로고
    • Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases
    • Masi G, Loupakis F, Pollina L, Vasile E, Cupini S, Ricci S, Brunetti IM, Ferraldeschi R, Naso G, Filipponi F, Pietrabissa A, et al: Long-term outcome of initially unresectable metastatic colorectal cancer patients treated with 5-fluorouracil/leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) followed by radical surgery of metastases. Ann Surg 249: 420-425, 2009.
    • (2009) Ann Surg , vol.249 , pp. 420-425
    • Masi, G.1    Loupakis, F.2    Pollina, L.3    Vasile, E.4    Cupini, S.5    Ricci, S.6    Brunetti, I.M.7    Ferraldeschi, R.8    Naso, G.9    Filipponi, F.10    Pietrabissa, A.11
  • 61
    • 23844448040 scopus 로고    scopus 로고
    • Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates
    • DOI 10.1093/annonc/mdi246
    • Folprecht G, Grothey A, Alberts S, et al: Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates. Ann Oncol 16: 1311-1319, 2005. (Pubitemid 41158476)
    • (2005) Annals of Oncology , vol.16 , Issue.8 , pp. 1311-1319
    • Folprecht, G.1    Grothey, A.2    Alberts, S.3    Raab, H.-R.4    Kohne, C.-H.5
  • 62
    • 33750961459 scopus 로고    scopus 로고
    • Benefits and risks of neoadjuvant therapy for liver metastases
    • DOI 10.1200/JCO.2006.07.9244
    • Nordlinger B and Benoist S: Benefits and risks of neoadjuvant therapy for liver metastases. J Clin Oncol 24: 4954-4955, 2006. (Pubitemid 46631395)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.31 , pp. 4954-4955
    • Nordlinger, B.1    Benoist, S.2
  • 64
    • 0036721291 scopus 로고    scopus 로고
    • Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): A meta-analysis
    • Kinkel K, Lu Y, Both M, Warren RS and Thoeni RF: Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): a meta-analysis. Radiology 224: 748-756, 2002. (Pubitemid 34919808)
    • (2002) Radiology , vol.224 , Issue.3 , pp. 748-756
    • Kinkel, K.1    Lu, Y.2    Both, M.3    Warren, R.S.4    Thoeni, R.F.5


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