Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: A double-blind, placebo-controlled randomized study

Colorectal Disease

Volumn 14, Issue 6, 2012, Pages 776-782

  Andersen, J ^a   Christensen, H ^b   Pachler, J H ^a   Hallin, M ^a   Thaysen, H V ^b   Kehlet, H ^c  

^a HVIDOVRE HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

Colonic surgery; Fast track surgery; Laxative; Magnesia

Indexed keywords

MAGNESIUM OXIDE; PLACEBO;

ADULT; ARTICLE; COLON RESECTION; CONTROLLED STUDY; DEFECATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FATIGUE; FEMALE; FLATULENCE; FOOD INTAKE; GASTROINTESTINAL TRACT FUNCTION; HEMICOLECTOMY; HOSPITALIZATION; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MOBILIZATION; OUTCOME ASSESSMENT; POSTOPERATIVE NAUSEA; POSTOPERATIVE PAIN; POSTOPERATIVE VOMITING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIGMOIDECTOMY;

ADULT; AGED; AGED, 80 AND OVER; COLON; DEFECATION; DOUBLE-BLIND METHOD; FEMALE; GASTROINTESTINAL MOTILITY; HUMANS; LAXATIVES; LENGTH OF STAY; MAGNESIUM OXIDE; MALE; MIDDLE AGED; POSTOPERATIVE PERIOD; RECOVERY OF FUNCTION; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 84860713132     PISSN: 14628910     EISSN: 14631318     Source Type: Journal    
DOI: 10.1111/j.1463-1318.2011.02796.x     Document Type: Article

References (15)

1. Kehlet H. Postoperative ileus - an update on preventive techniques. Nat Clin Pract Gastroenterol Hepatol 2008; 5: 552-8.
2. Basse L, Thorbol JE, Lossl K, Kehlet H. Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 2004; 47: 271-7.
3. Kehlet H, Wilmore DW. Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg 2008; 248: 189-98.
4. Kehlet H. Fast-track colorectal surgery. Lancet 2008; 371: 791-3.
5. Gouvas N, Tan E, Windsor A, Xynos E, Tekkis PP. Fast-track vs standard care in colorectal surgery: a meta-analysis update. Int J Colorectal Dis 2009; 24: 1119-31.
6. Kehlet H, Büchler MW, Beart RW Jr, Billingham RP, Williamson R. Care after colonic operation - is it evidence-based? Results from a multinational survey in Europe and the United States. J Am Coll Surg 2006; 202: 45-54.
7. Fearon KC, Ljungqvist O, Von Meyenfeldt M et al. Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection. Clin Nutr 2005; 24: 466-77.
8. Holte K, Kehlet H. Postoperative ileus: a preventable event. Br J Surg 2000; 87: 1480-93.
9. Mattei P, Rombeau JL. Review of the pathophysiology and management of postoperative ileus. World J Surg 2006; 30: 1382-91.
10. Wind J, Hofland J, Preckel B et al. Perioperative strategy in colonic surgery; LAparoscopy and/or Fast track multimodal management versus standard care (LAFA trial). BMC Surg 2006; 6: 16.
11. Hansen CT, Sorensen M, Moller C, Ottesen B, Kehlet H. Effect of laxatives on gastrointestinal functional recovery in fast-track hysterectomy: a double-blind, placebo-controlled randomized study. Am J Obstet Gynecol 2007; 196: 311-7.
12. Hendry PO, van Dam RM, Bukkems SFFW et al. Randomized clinical trial of laxatives and oral nutritional supplements within an enhanced recovery after surgery protocol following liver resection. Br J Surg 2010; 97: 1198-206.
13. Zingg U, Miskovic D, Pasternak I, Meyer P, Hammel CT, Metzger U. Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial. Int J Colorectal Dis 2008; 23: 1175-83.
14. Holte K, Kehlet H. Postoperative ileus: progress towards effective management. Drugs 2002; 62: 2603-15.
15. Andersen J, Hjort-Jakobsen D, Christiansen PS, Kehlet H. Readmission rates after a planned hospital stay of 2 versus 3days in fast-track colonic surgery. Br J Surg 2007; 94: 890-3.