Evaluation of selective tumor detection by clinical magnetic resonance imaging using antibody-conjugated superparamagnetic iron oxide

Journal of Controlled Release

Volumn 159, Issue 3, 2012, Pages 413-418

  Koyama, Takayoshi ^a   Shimura, Mari ^a   Minemoto, Yuzuru ^a   Nohara, Satoshi ^b   Shibata, Sayaka ^c   Iida, Yutaka ^d   Iwashita, Shinki ^e   Hasegawa, Masakatsu ^b   Kurabayashi, Tohru ^f   Hamada, Hirofumi ^g   Kono, Kenji ^h   Honda, Eiichi ⁱ   Aoki, Ichio ^c   Ishizaka, Yukihito ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b Nagoya Research Laboratory   (Japan)

^c NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^d TORAY RESEARCH CENTER INC   (Japan)

^e RandD Division   (Japan)

^f TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^g SAPPORO MEDICAL UNIVERSITY   (Japan)

^h Osaka Prefecture University   (Japan)

ⁱ UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Clinical 1.5 T MRI; CMDM; Monoclonal antibodies; SPIO; Tumor targeting

Indexed keywords

ACTIVE TARGETING; CLINICAL 1.5 T-MRI; CLINICAL APPLICATION; CMDM; GENETIC BACKGROUNDS; IN-VIVO; MONOCLONAL ANTIBODIES (MABS); NANO-SIZE; SPECIFIC DETECTION; SPIO; SUPERPARAMAGNETIC IRON OXIDES; TUMOR DETECTION; TUMOR-TARGETING;

CHEMICAL DETECTION; IRON OXIDES; MAGNETIC RESONANCE IMAGING; MAMMALS; MONOCLONAL ANTIBODIES; SUPERPARAMAGNETISM; SURFACE PLASMON RESONANCE; TUMORS;

DIAGNOSIS;

ANTIBODY CONJUGATE; DEXTRAN; MONOCLONAL ANTIBODY; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TUMOR CELL; TUMOR DIAGNOSIS;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; CONTRAST MEDIA; DEXTRANS; FEMALE; FLUORESCENT DYES; IMMUNOGLOBULIN G; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NEOPLASMS; NIH 3T3 CELLS; PARTICLE SIZE;

EID: 84860673311     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.01.023     Document Type: Article

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