Highly sensitive and rapid profiling method for carotenoids and their epoxidized products using supercritical fluid chromatography coupled with electrospray ionization-triple quadrupole mass spectrometry

Journal of Bioscience and Bioengineering

Volumn 113, Issue 6, 2012, Pages 782-787

  Matsubara, Atsuki ^a   Uchikata, Takato ^a   Shinohara, Masakazu ^b   Nishiumi, Shin ^b   Yoshida, Masaru ^b   Fukusaki, Eiichiro ^a   Bamba, Takeshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Carotenoids; Epoxy carotenoids; Oxidative stress marker; Supercritical fluid chromatography; Tandem mass spectrometry

Indexed keywords

CAROTENOIDS; EPOXY CAROTENOIDS; OXIDATIVE STRESS MARKERS; SUPER CRITICAL FLUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

BODY FLUIDS; ELECTROSPRAY IONIZATION; EPOXIDATION; GAS CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETRY; OXIDATIVE STRESS; SEPARATION;

PIGMENTS;

CAROTENOID; EPOXY CAROTENOID; LOW DENSITY LIPOPROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ELECTROSPRAY IONIZATION TRIPLE QUADRUPOLE MASS SPECTROMETRY; EPOXIDATION; HUMAN; MASS SPECTROMETRY; OXIDATIVE STRESS; SENSITIVITY ANALYSIS; SUPERCRITICAL FLUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

CAROTENOIDS; CHROMATOGRAPHY, SUPERCRITICAL FLUID; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84860625790     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2012.01.017     Document Type: Article

References (34)

1. Rando R.R. Polyenes and vision. Chem. Biol. 1996, 3:255-262.
2. Rao A.V., Rao L.G. Carotenoids and human health. Pharmacol. Res. 2007, 55:207-216.
3. Rooyen J., Esterhuyse A.J., Engelbrecht A.M., Toit E.F. Health benefits of a natural carotenoid rich oil: a proposed mechanism of protection against ischaemia/reperfusion injury. Asia Pac. J. Clin. Nutr. 2008, 17:316-319.
4. Semba R.D., Lauretani F., Ferrucci L. Carotenoids as protection against sarcopenia in older adults. Arch. Biochem. Biophys. 2007, 458:141-145.
5. Voutilainen S., Nurmi T., Mursu J., Rissanen T.H. Carotenoids and cardiovascular health. Am. J. Clin. 2006, 83:1265-1271.
6. Heinonen O.P., Huttunen J.K., Albanes D., Haapakoski J., Palmgren J., Pietinen P., Pikkarainen J., Rautalahti M., Virtamo J., Edwards B.K., other 113 authors The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 1994, 330:1029-1035.
7. Omenn G.S., Goodman G.E., Thornquist M.D., Balmes J., Cullen M.R., Glass A., Keogh J.P., Meyskens F.L., Valanis B., Williams J.H., other 2 authors Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl. J. Med. 1996, 334:1150-1155.
8. Lowe G.M., Vlismas K., Graham D.L., Carail M., Caris-Veyrat C., Young A.J. The degradation of (all-E)-β-carotene by cigarette smoke. Free Radic. Res. 2009, 43:280-286.
9. Yamauchi R., Tsuchihashi K., Kato K. Oxidation products of beta-carotene during the peroxidation of methyl linoleate in the bulk phase. Biosci. Biotechnol. Biochem. 1998, 62:1301-1306.
10. Yeh S.-L., Hu M.-L. Induction of oxidative DNA damage in human foreskin fibroblast Hs68 cells by oxidized beta-carotene and lycopene. Free Radic. Res. 2001, 35:203-213.
11. Salgo M.G., Cueto R., Winston G.W., Pryor W.A. Beta carotene and its oxidation products have different effects on microsome mediated binding of benzo[a]pyrene to DNA. Free Radic. Biol. Med. 1999, 26:162-173.
12. Rodriguez-Bernaldo de Quiros A., Costa H. Analysis of carotenoids in vegetable and plasma samples: a review. J. Food Compos. Anal. 2006, 19:97-111.
13. Meléndez-Martínez A.J., Vicario I.M., Heredia F.J. Review: analysis of carotenoids in orange juice. J. Food Compos. Anal. 2007, 20:638-649.
14. Smith R.M. Supercritical fluids in separation science-the dreams, the reality, and the future. J. Chromatogr. 1999, 856:83-115.
15. Taylor L.T. Supercritical fluid chromatography for the 21st century. J. Supercrit. Fluids 2009, 47:566-573.
16. Bamba T., Shimonishi N., Matsubara A., Hirata K., Nakazawa Y., Kobayashi A., Fukusaki E. High throughput and exhaustive analysis of diverse lipids by using supercritical fluid chromatography-mass spectrometry for metabolomics. J. Biosci. Bioeng. 2008, 105:460-469.
17. Matsubara A., Bamba T., Ishida H., Fukusaki E., Hirata K. Highly sensitive and accurate profiling of carotenoids by supercritical fluid chromatography coupled with mass spectrometry. J. Sep. Sci. 2009, 32:1459-1464.
18. Wada Y., Matsubara A., Uchikata T., Iwasaki Y., Morimoto S., Kan K., Okura T., Fukusaki E., Bamba T. Metabolic profiling of β-cryptoxanthn and its fatty acid esters by supercritical fluid chromatography coupled with triple quadrupole mass spectrometry. J. Sep. Sci. 2011, 34:3546-3552.
19. Matsubara A., Fukusaki E., Bamba T. Metabolite analysis by supercritical fluid chromatography. Bioanalysis 2010, 2:27-34.
20. Barua A.B. Intestinal absorption of epoxy-beta-carotenes by humans. Biochem. J. 1999, 339:359-362.
21. Chopra M., O'Neill M.E., Keogh N., Wortley G., Southon S., Thurnham D.I. Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers. Clin. Chem. 2000, 46:1818-1129.
22. Heath D.D., Li H., Letcher R.J., Tyndale S.T. Determination of carotenoids and all-trans-retinol in fish eggs by liquid chromatography-electrospray ionization-tandem mass spectrometry. J. Chromatogr. B 2005, 816:49-56.
23. Mercadante A.Z., Rodriguez-Amaya D.B., Britton G. HPLC and mass spectrometric analysis of carotenoids from mango. J. Agric. Food Chem. 1997, 45:120-123.
24. Maoka T., Fujiwara Y., Hashimoto K., Akimoto N. Characterization of epoxy carotenoids by fast atom bombardment collision-induced dissociation MS/MS. Lipids 2004, 39:179-183.
25. Rosso V., Mercadante A. Identification and quantification of carotenoids, by HPLC-PDA-MS/MS, from Amazonian fruits. J. Agric. Food Chem. 2007, 55:5062-5072.
26. Chauveau-Duriot B., Doreau M., Nozière P., Graulet B. Simultaneous quantification of carotenoids, retinol, and tocopherols in forages, bovine plasma, and milk: validation of a novel UPLC method. Anal. Bioanal. Chem. 2010, 397:777-790.
27. Khachik F., Spangler C.J., Smith J.C., Canfield L.M., Steck A., Pfander H. Identification, quantification, and relative concentrations of carotenoids and their metabolites in human milk and serum. Anal. Chem. 1997, 69:1873-1881.
28. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 1989, 320:915-924.
29. Witztum J.L. The oxidation hypothesis of atherosclerosis. Lancet 1994, 344:793-795.
30. Itabe H. Oxidized low-density lipoproteins: what is understood and what remains to be clarified. Biol. Pharm. Bull. 2003, 26:1-9.
31. Yamaguchi Y., Kunitomo M., Haginaka J. Assay methods of modified lipoproteins in plasma. J. Chromatogr. B 2002, 781:313-330.
32. Steinerová A., Racek J., Stozický F., Zima T., Fialová L., Lapin A. Antibodies against oxidized LDL-theory and clinical use. Physiol. Res. 2001, 50:131-141.
33. Dugas T.R., Morel D.W., Harrison E.H. Impact of LDL carotenoid and alpha-tocopherol content on LDL oxidation by endothelial cells in culture. J. Lipid Res. 1998, 39:999-1007.
34. Romanchik J. Addition of lutein, lycopene, or β-carotene to LDL or serum in vitro: effects on carotenoid distribution, LDL composition, and LDL oxidation. J. Nutr. Biochem. 1997, 8:681-688.