메뉴 건너뛰기




Volumn 28, Issue 12, 2011, Pages 1045-1058

Hormone-responsive breast cancer

Author keywords

Adjuvant therapy; Aromatase; Aromatase inhibitors; Breast cancer; Cytochrome p450; Endocrine therapy; Estrogen receptor; Extended therapy; HER 2; Sequential therapy

Indexed keywords

ANDROGEN; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CYTOCHROME P450; LETROZOLE; LIPID; NITRILE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TRIAZOLE DERIVATIVE;

EID: 84860569989     PISSN: 0741238X     EISSN: 18658652     Source Type: Journal    
DOI: 10.1007/s12325-011-0075-4     Document Type: Review
Times cited : (21)

References (71)
  • 2
    • 0034086613 scopus 로고    scopus 로고
    • Breast cancer prevention: A review of current evidence
    • Vogel VG. Breast cancer prevention: a review of current evidence. CA Cancer J Clin. 2000;50:156-170.
    • (2000) CA Cancer J Clin , vol.50 , pp. 156-170
    • Vogel, V.G.1
  • 3
    • 84893386274 scopus 로고    scopus 로고
    • NHS Breast Screening Programme and Association of Breast Surgery at BASO, Last accessed May 5, 2011
    • NHS Breast Screening Programme and Association of Breast Surgery at BASO. Audit of screen detected breast cancers for the year of screening April 2004 to March 2005. Available at: http://www. cancerscreening.nhs.uk/breastscreen/ publications/baso2004-2005.pdf. Last accessed May 5, 2011.
    • Audit of Screen Detected Breast Cancers for the Year of Screening April 2004 to March 2005
  • 4
    • 85044709641 scopus 로고    scopus 로고
    • Hormonal therapies for early breast cancer: Systematic review and economic evaluation
    • Jul, ix-xi, 1-134. Availabe at: http://www.hta.nhs.uk/pdfexecs/summ1126. pdf. Last accessed May 5, 2011
    • Hind D, Ward S, De Nigris E, Simpson E, Carroll C, Wyld L. Hormonal therapies for early breast cancer: systematic review and economic evaluation. Health Technol Assess. 2007 Jul; 11 (26): iii-iv, ix-xi, 1-134. Availabe at: http://www.hta.nhs.uk/pdfexecs/summ1126.pdf. Last accessed May 5, 2011.
    • (2007) Health Technol Assess , vol.11 , Issue.26
    • Hind, D.1    Ward, S.2    De Nigris, E.3    Simpson, E.4    Carroll, C.5    Wyld, L.6
  • 6
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet. 1998;351:1451-1467.
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 7
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005 ;365:1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 8
    • 28044461469 scopus 로고    scopus 로고
    • When to recommend and to pay for first-line adjuvant breast cancer treatment? A structured review of the literature
    • Kilian R, Porzsolt F. When to recommend and to pay for first-line adjuvant breast cancer treatment? A structured review of the literature. Breast. 2005;14:636-642.
    • (2005) Breast , vol.14 , pp. 636-642
    • Kilian, R.1    Porzsolt, F.2
  • 9
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A, Cuzick J, Baum M, et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet. 2005;365:60-62.
    • (2005) Lancet , vol.365 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3
  • 10
    • 17144423592 scopus 로고    scopus 로고
    • Aromatase inhibition: Translation into a successful therapeutic approach
    • Geisler J, Lonning PE. Aromatase inhibition: translation into a successful therapeutic approach. Clin Cancer Res. 2005;11:2809-2821.
    • (2005) Clin Cancer Res , vol.11 , pp. 2809-2821
    • Geisler, J.1    Lonning, P.E.2
  • 11
    • 77649189240 scopus 로고    scopus 로고
    • Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women
    • Gibson L, Lawrence D, Dawson C, Bliss J. Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. Cochrane Database Syst Rev. 2009:CD003370.
    • (2009) Cochrane Database Syst Rev
    • Gibson, L.1    Lawrence, D.2    Dawson, C.3    Bliss, J.4
  • 12
    • 40649108301 scopus 로고    scopus 로고
    • Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: A systematic review
    • Eisen A, Trudeau M, Shelley W, Messersmith H, Pritchard KI. Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review. Cancer Treat Rev. 2008;34:157-174.
    • (2008) Cancer Treat Rev , vol.34 , pp. 157-174
    • Eisen, A.1    Trudeau, M.2    Shelley, W.3    Messersmith, H.4    Pritchard, K.I.5
  • 14
    • 0032836573 scopus 로고    scopus 로고
    • Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer
    • Dowsett M, Pfister C, Johnston SR, et al. Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer. Clin Cancer Res. 1999;5:2338-2343.
    • (1999) Clin Cancer Res , vol.5 , pp. 2338-2343
    • Dowsett, M.1    Pfister, C.2    Johnston, S.R.3
  • 15
    • 0035207127 scopus 로고    scopus 로고
    • Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients
    • Pfister CU, Martoni A, Zamagni C, et al. Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients. Biopharm Drug Dispos. 2001;22:191-197.
    • (2001) Biopharm Drug Dispos , vol.22 , pp. 191-197
    • Pfister, C.U.1    Martoni, A.2    Zamagni, C.3
  • 16
    • 0141428055 scopus 로고    scopus 로고
    • Pharmacokinetics of third-generation aromatase inhibitors
    • Lonning P, Pfister C, Martoni A, Zamagni C. Pharmacokinetics of third-generation aromatase inhibitors. Semin Oncol. 2003;30(Suppl. 14):23-32.
    • (2003) Semin Oncol , vol.30 , Issue.SUPPL. 14 , pp. 23-32
    • Lonning, P.1    Pfister, C.2    Martoni, A.3    Zamagni, C.4
  • 18
    • 34948879654 scopus 로고    scopus 로고
    • The discovery and mechanism of action of letrozole
    • Bhatnagar AS. The discovery and mechanism of action of letrozole. Breast Cancer Res Treat. 2007;105(Suppl. 1):7-17.
    • (2007) Breast Cancer Res Treat , vol.105 , Issue.SUPPL. 1 , pp. 7-17
    • Bhatnagar, A.S.1
  • 21
    • 0032711815 scopus 로고    scopus 로고
    • The effect of combining aromatase inhibitors with antiestrogens on tumor growth in a nude mouse model for breast cancer
    • Lu Q, Liu Y, Long BJ, Grigoryev D, Gimbel M, Brodie A. The effect of combining aromatase inhibitors with antiestrogens on tumor growth in a nude mouse model for breast cancer. Breast Cancer Res Treat. 1999;57:183-192.
    • (1999) Breast Cancer Res Treat , vol.57 , pp. 183-192
    • Lu, Q.1    Liu, Y.2    Long, B.J.3    Grigoryev, D.4    Gimbel, M.5    Brodie, A.6
  • 22
    • 0036807501 scopus 로고    scopus 로고
    • The evolving role of aromatase inhibitors in breast cancer
    • Mokbel K. The evolving role of aromatase inhibitors in breast cancer. Int J Clin Oncol. 2002;7:279-283.
    • (2002) Int J Clin Oncol , vol.7 , pp. 279-283
    • Mokbel, K.1
  • 23
    • 10744233578 scopus 로고    scopus 로고
    • Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status
    • Ellis MJ, Coop A, Singh B, et al. Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status. Cancer Res. 2003;63:6523-6531.
    • (2003) Cancer Res , vol.63 , pp. 6523-6531
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 24
    • 61449148696 scopus 로고    scopus 로고
    • A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women
    • Murray J, Young OE, Renshaw L, et al. A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women. Breast Cancer Res Treat. 2009;114:495-501.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 495-501
    • Murray, J.1    Young, O.E.2    Renshaw, L.3
  • 25
    • 0029560237 scopus 로고
    • In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with breast cancer
    • Dowsett M, Jones A, Johnston SR, Jacobs S, Trunet P, Smith IE. In vivo measurement of aromatase inhibition by letrozole (CGS 20267) in postmenopausal patients with breast cancer. Clin Cancer Res. 1995;1:1511-1515.
    • (1995) Clin Cancer Res , vol.1 , pp. 1511-1515
    • Dowsett, M.1    Jones, A.2    Johnston, S.R.3    Jacobs, S.4    Trunet, P.5    Smith, I.E.6
  • 26
    • 0036467847 scopus 로고    scopus 로고
    • Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study
    • Geisler J, Haynes B, Anker G, Dowsett M, Lonning PE. Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. J Clin Oncol. 2002;20:751-757.
    • (2002) J Clin Oncol , vol.20 , pp. 751-757
    • Geisler, J.1    Haynes, B.2    Anker, G.3    Dowsett, M.4    Lonning, P.E.5
  • 27
    • 58149145625 scopus 로고    scopus 로고
    • Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels
    • Geisler J, Helle H, Ekse D, et al. Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels. Clin Cancer Res. 2008;14:6330-6335.
    • (2008) Clin Cancer Res , vol.14 , pp. 6330-6335
    • Geisler, J.1    Helle, H.2    Ekse, D.3
  • 28
    • 0032974458 scopus 로고    scopus 로고
    • Biology of aromatase inhibitors: Pharmacology/endocrinology within the breast
    • Miller WR. Biology of aromatase inhibitors: pharmacology/endocrinology within the breast. Endocr Relat Cancer. 1999;6:187-195.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 187-195
    • Miller, W.R.1
  • 29
    • 0035716365 scopus 로고    scopus 로고
    • Local endocrine effects of aromatase inhibitors within the breast
    • Miller WR, Dixon JM. Local endocrine effects of aromatase inhibitors within the breast. J Steroid Biochem Mol Biol. 2001;79:93-102.
    • (2001) J Steroid Biochem Mol Biol , vol.79 , pp. 93-102
    • Miller, W.R.1    Dixon, J.M.2
  • 31
    • 0033082373 scopus 로고    scopus 로고
    • Double-blind, randomised, multicentre endocrine trial comparing two letrozole doses, in postmenopausal breast cancer patients
    • Bajetta E, Zilembo N, Dowsett M, et al. Double-blind, randomised, multicentre endocrine trial comparing two letrozole doses, in postmenopausal breast cancer patients. Eur J Cancer. 1999;35:208-213.
    • (1999) Eur J Cancer , vol.35 , pp. 208-213
    • Bajetta, E.1    Zilembo, N.2    Dowsett, M.3
  • 32
    • 0027535830 scopus 로고
    • Phase i study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer
    • Iveson TJ, Smith IE, Ahern J, Smithers DA, Trunet PF, Dowsett M. Phase I study of the oral nonsteroidal aromatase inhibitor CGS 20267 in postmenopausal patients with advanced breast cancer. Cancer Res. 1993;53:266-270.
    • (1993) Cancer Res , vol.53 , pp. 266-270
    • Iveson, T.J.1    Smith, I.E.2    Ahern, J.3    Smithers, D.A.4    Trunet, P.F.5    Dowsett, M.6
  • 33
    • 0029114143 scopus 로고
    • Use of ultrasensitive recombinant cell bioassay to measure estrogen levels in women with breast cancer receiving the aromatase inhibitor, letrozole
    • Klein KO, Demers LM, Santner SJ, Baron J, Cutler GB, Jr., Santen RJ. Use of ultrasensitive recombinant cell bioassay to measure estrogen levels in women with breast cancer receiving the aromatase inhibitor, letrozole. J Clin Endocrinol Metab. 1995;80:2658-2660.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2658-2660
    • Klein, K.O.1    Demers, L.M.2    Santner, S.J.3    Baron, J.4    Cutler Jr., G.B.5    Santen, R.J.6
  • 35
    • 67650337804 scopus 로고    scopus 로고
    • Endocrine effects of adjuvant letrozole compared with tamoxifen in hormone-responsive postmenopausal patients with early breast cancer: The HOBOE trial
    • Rossi E, Morabito A, Di Rella F, et al. Endocrine effects of adjuvant letrozole compared with tamoxifen in hormone-responsive postmenopausal patients with early breast cancer: the HOBOE trial. J Clin Oncol. 2009;27:3192-3197.
    • (2009) J Clin Oncol , vol.27 , pp. 3192-3197
    • Rossi, E.1    Morabito, A.2    Di Rella, F.3
  • 36
    • 43249113162 scopus 로고    scopus 로고
    • Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer
    • Dixon JM, Renshaw L, Young O, et al. Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer. J Clin Oncol. 2008;26:1671-1676.
    • (2008) J Clin Oncol , vol.26 , pp. 1671-1676
    • Dixon, J.M.1    Renshaw, L.2    Young, O.3
  • 37
    • 34948815626 scopus 로고    scopus 로고
    • Letrozole in the extended adjuvant setting: MA-17
    • Goss PE. Letrozole in the extended adjuvant setting: MA-17. Breast Cancer Res Treat. 2007;105(Suppl. 1):45-53.
    • (2007) Breast Cancer Res Treat , vol.105 , Issue.SUPPL. 1 , pp. 45-53
    • Goss, P.E.1
  • 38
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
    • Thurlimann B, Keshaviah A, Coates AS, et al. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med. 2005;353:2747-2757.
    • (2005) N Engl J Med , vol.353 , pp. 2747-2757
    • Thurlimann, B.1    Keshaviah, A.2    Coates, A.S.3
  • 39
    • 0042591537 scopus 로고    scopus 로고
    • Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy
    • Brodie AH, Mouridsen HT. Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy. Am J Clin Oncol. 2003;26:S17-26.
    • (2003) Am J Clin Oncol , vol.26
    • Brodie, A.H.1    Mouridsen, H.T.2
  • 40
    • 20444448539 scopus 로고    scopus 로고
    • Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model
    • Jelovac D, Macedo L, Goloubeva OG, Handratta V, Brodie AM. Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model. Cancer Res. 2005;65:5439-5444.
    • (2005) Cancer Res , vol.65 , pp. 5439-5444
    • Jelovac, D.1    Macedo, L.2    Goloubeva, O.G.3    Handratta, V.4    Brodie, A.M.5
  • 41
    • 0030480630 scopus 로고    scopus 로고
    • Novel non-steroidal aromatase inhibitors: Are there new perspectives in the treatment of breast cancer?
    • Bajetta E, Celio L, Buzzoni R, Bichisao E. Novel non-steroidal aromatase inhibitors: are there new perspectives in the treatment of breast cancer? Tumori. 1996;82:417-22.
    • (1996) Tumori , vol.82 , pp. 417-422
    • Bajetta, E.1    Celio, L.2    Buzzoni, R.3    Bichisao, E.4
  • 42
    • 0037242971 scopus 로고    scopus 로고
    • Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors
    • Buzdar AU. Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors. Clin Cancer Res. 2003;9(1 Pt 2):468S-72S.
    • (2003) Clin Cancer Res , vol.9 , Issue.1 PART 2
    • Buzdar, A.U.1
  • 43
    • 67650688364 scopus 로고    scopus 로고
    • Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer
    • Nabholtz JM, Mouret-Reynier MA, Durando X, et al. Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer. Expert Opin Pharmacother. 2009;10:1435-1447.
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 1435-1447
    • Nabholtz, J.M.1    Mouret-Reynier, M.A.2    Durando, X.3
  • 44
    • 0034885923 scopus 로고    scopus 로고
    • Effect of letrozole on the lipid profile in postmenopausal women with breast cancer
    • Elisaf MS, Bairaktari ET, Nicolaides C, et al. Effect of letrozole on the lipid profile in postmenopausal women with breast cancer. Eur J Cancer. 2001;37:1510-1513.
    • (2001) Eur J Cancer , vol.37 , pp. 1510-1513
    • Elisaf, M.S.1    Bairaktari, E.T.2    Nicolaides, C.3
  • 45
    • 0029081347 scopus 로고
    • Plasma changes in breast cancer patients during endocrine therapy-lipid measurements and nuclear magnetic resonance (NMR) spectroscopy
    • Engan T, Krane J, Johannessen DC, Lonning PE, Kvinnsland S. Plasma changes in breast cancer patients during endocrine therapy-lipid measurements and nuclear magnetic resonance (NMR) spectroscopy. Breast Cancer Res Treat. 1995;36:287-297.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 287-297
    • Engan, T.1    Krane, J.2    Johannessen, D.C.3    Lonning, P.E.4    Kvinnsland, S.5
  • 46
    • 0036317949 scopus 로고    scopus 로고
    • Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: A pilot study for breast cancer prevention
    • Harper-Wynne C, Ross G, Sacks N, et al. Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention. Cancer Epidemiol Biomarkers Prev. 2002;11:614-621.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 614-621
    • Harper-Wynne, C.1    Ross, G.2    Sacks, N.3
  • 47
    • 34249936011 scopus 로고    scopus 로고
    • Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA-17
    • Goss PE, Ingle JN, Martino S, et al. Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA-17. J Clin Oncol. 2007;25:2006-2011.
    • (2007) J Clin Oncol , vol.25 , pp. 2006-2011
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 48
    • 33747058527 scopus 로고    scopus 로고
    • Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: A companion study to NCIC CTG MA-17
    • Perez EA, Josse RG, Pritchard KI, et al. Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: a companion study to NCIC CTG MA-17. J Clin Oncol. 2006;24:3629-3635.
    • (2006) J Clin Oncol , vol.24 , pp. 3629-3635
    • Perez, E.A.1    Josse, R.G.2    Pritchard, K.I.3
  • 49
    • 20044380552 scopus 로고    scopus 로고
    • The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA-17L)
    • Wasan KM, Goss PE, Pritchard PH, et al. The influence of letrozole on serum lipid concentrations in postmenopausal women with primary breast cancer who have completed 5 years of adjuvant tamoxifen (NCIC CTG MA-17L). Ann Oncol. 2005;16:707-715.
    • (2005) Ann Oncol , vol.16 , pp. 707-715
    • Wasan, K.M.1    Goss, P.E.2    Pritchard, P.H.3
  • 50
    • 0035710547 scopus 로고    scopus 로고
    • A summary of second-line randomized studies of aromatase inhibitors
    • Buzdar AU. A summary of second-line randomized studies of aromatase inhibitors. J Steroid Biochem Mol Biol. 2001;79:109-114.
    • (2001) J Steroid Biochem Mol Biol , vol.79 , pp. 109-114
    • Buzdar, A.U.1
  • 51
    • 0034913582 scopus 로고    scopus 로고
    • Letrozole as primary medical therapy for locally advanced and large operable breast cancer
    • Dixon JM, Love CD, Bellamy CO, et al. Letrozole as primary medical therapy for locally advanced and large operable breast cancer. Breast Cancer Res Treat. 2001;66:191-199.
    • (2001) Breast Cancer Res Treat , vol.66 , pp. 191-199
    • Dixon, J.M.1    Love, C.D.2    Bellamy, C.O.3
  • 52
    • 0035692576 scopus 로고    scopus 로고
    • Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicenter study
    • Eiermann W, Paepke S, Appfelstaedt J, et al. Preoperative treatment of postmenopausal breast cancer patients with letrozole: A randomized double-blind multicenter study. Ann Oncol. 2001;12:1527-1532.
    • (2001) Ann Oncol , vol.12 , pp. 1527-1532
    • Eiermann, W.1    Paepke, S.2    Appfelstaedt, J.3
  • 53
    • 0030927955 scopus 로고    scopus 로고
    • A randomized phase II trial of two dosage levels of letrozole as thirdline hormonal therapy for women with metastatic breast carcinoma
    • Ingle JN, Johnson PA, Suman VJ, et al. A randomized phase II trial of two dosage levels of letrozole as thirdline hormonal therapy for women with metastatic breast carcinoma. Cancer. 1997;80:218-224.
    • (1997) Cancer , vol.80 , pp. 218-224
    • Ingle, J.N.1    Johnson, P.A.2    Suman, V.J.3
  • 54
    • 33947510501 scopus 로고    scopus 로고
    • Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98
    • Coates AS, Keshaviah A, Thurlimann B, et al. Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: update of study BIG 1-98. J Clin Oncol. 2007;25:486-492.
    • (2007) J Clin Oncol , vol.25 , pp. 486-492
    • Coates, A.S.1    Keshaviah, A.2    Thurlimann, B.3
  • 55
    • 69049113989 scopus 로고    scopus 로고
    • Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer
    • Mouridsen H, Giobbie-Hurder A, Goldhirsch A, et al. Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer. N Engl J Med. 2009;361:766-776.
    • (2009) N Engl J Med , vol.361 , pp. 766-776
    • Mouridsen, H.1    Giobbie-Hurder, A.2    Goldhirsch, A.3
  • 56
    • 0038460245 scopus 로고    scopus 로고
    • Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: Analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group
    • Mouridsen H, Gershanovich M, Sun Y, et al. Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol. 2003;21:2101-2109.
    • (2003) J Clin Oncol , vol.21 , pp. 2101-2109
    • Mouridsen, H.1    Gershanovich, M.2    Sun, Y.3
  • 57
    • 0343584508 scopus 로고    scopus 로고
    • Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: Results of a phase III study of the International Letrozole Breast Cancer Group
    • Mouridsen H, Gershanovich M, Sun Y, et al. Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group. J Clin Oncol. 2001;19:2596-2606.
    • (2001) J Clin Oncol , vol.19 , pp. 2596-2606
    • Mouridsen, H.1    Gershanovich, M.2    Sun, Y.3
  • 58
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial
    • Ellis MJ, Coop A, Singh B, et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol. 2001;19:3808-3816.
    • (2001) J Clin Oncol , vol.19 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3
  • 60
    • 77649100030 scopus 로고    scopus 로고
    • Lapatinib plus letrozole as first-line therapy for HER-2+ hormone receptorpositive metastatic breast cancer
    • Schwartzberg LS, Franco SX, Florance A, O'Rourke L, Maltzman J, Johnston S. Lapatinib plus letrozole as first-line therapy for HER-2+ hormone receptorpositive metastatic breast cancer. Oncologist. 2010;15:122-129.
    • (2010) Oncologist , vol.15 , pp. 122-129
    • Schwartzberg, L.S.1    Franco, S.X.2    Florance, A.3    O'Rourke, L.4    Maltzman, J.5    Johnston, S.6
  • 61
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005;353:1659-1672.
    • (2005) N Engl J Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 62
    • 26844536978 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
    • Romond EH, Perez EA, Bryant J, et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med. 2005;353:1673-1684.
    • (2005) N Engl J Med , vol.353 , pp. 1673-1684
    • Romond, E.H.1    Perez, E.A.2    Bryant, J.3
  • 63
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001;344:783-792.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 64
    • 15744401575 scopus 로고    scopus 로고
    • Correlation of HER-2 status with estrogen and progesterone receptors and histologic features in 3,655 invasive breast carcinomas
    • Lal P, Tan LK, Chen B. Correlation of HER-2 status with estrogen and progesterone receptors and histologic features in 3,655 invasive breast carcinomas. Am J Clin Pathol. 2005;123:541-546.
    • (2005) Am J Clin Pathol , vol.123 , pp. 541-546
    • Lal, P.1    Tan, L.K.2    Chen, B.3
  • 65
    • 37549056583 scopus 로고    scopus 로고
    • Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: Supplementary results from the BIG 1-98 randomised trial
    • Rasmussen BB, Regan MM, Lykkesfeldt AE, et al. Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial. Lancet Oncol. 2008;9:23-28.
    • (2008) Lancet Oncol , vol.9 , pp. 23-28
    • Rasmussen, B.B.1    Regan, M.M.2    Lykkesfeldt, A.E.3
  • 66
    • 51549101729 scopus 로고    scopus 로고
    • A phase i and pharmacokinetic study of lapatinib in combination with letrozole in patients with advanced cancer
    • Chu QS, Cianfrocca ME, Goldstein LJ, et al. A phase I and pharmacokinetic study of lapatinib in combination with letrozole in patients with advanced cancer. Clin Cancer Res. 2008;14:4484-4490.
    • (2008) Clin Cancer Res , vol.14 , pp. 4484-4490
    • Chu, Q.S.1    Cianfrocca, M.E.2    Goldstein, L.J.3
  • 67
    • 73149115341 scopus 로고    scopus 로고
    • Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone-receptor metastasic breast cancer
    • Johnston S, Pippen J, Pivot X, et al. Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone-receptor metastasic breast cancer. J Clin Oncol. 2009;27:5538-5546.
    • (2009) J Clin Oncol , vol.27 , pp. 5538-5546
    • Johnston, S.1    Pippen, J.2    Pivot, X.3
  • 68
    • 77649100030 scopus 로고    scopus 로고
    • Lapatinib plus letrozole as first-line therapy for HER-2 positive hormone receptorpositive metastatic breast cancer
    • Schwartzberg LS, Franco S, Florane A, et al. Lapatinib plus letrozole as first-line therapy for HER-2 positive hormone receptorpositive metastatic breast cancer. Oncologist. 2010;15:122-129.
    • (2010) Oncologist , vol.15 , pp. 122-129
    • Schwartzberg, L.S.1    Franco, S.2    Florane, A.3
  • 69
    • 66849136781 scopus 로고    scopus 로고
    • Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer
    • Baselga J, Semiglazov V, van Dam P, et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. J Clin Oncol. 2009;27:2630-2637.
    • (2009) J Clin Oncol , vol.27 , pp. 2630-2637
    • Baselga, J.1    Semiglazov, V.2    Van Dam, P.3
  • 70
    • 79953222210 scopus 로고    scopus 로고
    • Combination of trastuzumab and letrozole after resistance to sequential trastuzumab and aromatase inhibitor monotherapies in patients with estrogen receptor-positive, HER- 2-positive advanced breast cancer: A proof-ofconcept trial (SAKK 23/03)
    • Koeberle D, Ruhstaller T, Jost L, et al. Combination of trastuzumab and letrozole after resistance to sequential trastuzumab and aromatase inhibitor monotherapies in patients with estrogen receptor-positive, HER- 2-positive advanced breast cancer: a proof-ofconcept trial (SAKK 23/03). Endocr Relat Cancer. 2011;18:257-64.
    • (2011) Endocr Relat Cancer , vol.18 , pp. 257-264
    • Koeberle, D.1    Ruhstaller, T.2    Jost, L.3
  • 71
    • 63049137792 scopus 로고    scopus 로고
    • Gene expression profiles differentiating between breast cancers clinically responsive or resistant to letrozole
    • Miller WR, Larionov A, Renshaw L, et al. Gene expression profiles differentiating between breast cancers clinically responsive or resistant to letrozole. J Clin Oncol. 2009;27:1382-1387.
    • (2009) J Clin Oncol , vol.27 , pp. 1382-1387
    • Miller, W.R.1    Larionov, A.2    Renshaw, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.