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Volumn 76, Issue 3, 2012, Pages 269-279

Maintenance treatment of advanced non-small-cell lung cancer: Results of an International Expert Panel Meeting of the Italian Association of Thoracic Oncology

(13)  Gridelli, Cesare a   de Marinis, Filippo b   Di Maio, Massimo c   Ardizzoni, Andrea d   Belani, Chandra P e   Cappuzzo, Federico f   Ciardiello, Fortunato g   Fidias, Panagiotis h   Paz Ares, Luis i   Perrone, Francesco c   Pirker, Robert j   De Petris, Luigi k   Stahel, Rolf l  


Author keywords

Bevacizumab; Cetuximab; Docetaxel; Erlotinib; Gefitinib; Gemcitabine; Maintenance; Non small cell lung cancer; Pemetrexed

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; GEMCITABINE; IFOSFAMIDE; MITOMYCIN; NAVELBINE; PACLITAXEL; PEMETREXED; PLATINUM DERIVATIVE; VASCULOTROPIN ANTIBODY;

EID: 84860537353     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.12.011     Document Type: Review
Times cited : (22)

References (34)
  • 1
    • 74949133978 scopus 로고    scopus 로고
    • American Society of Clinical Oncology. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer
    • Azzoli C.G., Baker S., Temin S., Pao W., Aliff T., Brahmer J., et al. American Society of Clinical Oncology. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2009, 27:6251-6266.
    • (2009) J Clin Oncol , vol.27 , pp. 6251-6266
    • Azzoli, C.G.1    Baker, S.2    Temin, S.3    Pao, W.4    Aliff, T.5    Brahmer, J.6
  • 2
    • 80053639884 scopus 로고    scopus 로고
    • 2011 focused update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on chemotherapy for stage IV non-small-cell lung cancer
    • [Epub ahead of print], September
    • Azzoli C.G., Temin S., Aliff T., Baker S., Brahmer J., Johnson D.H., et al. 2011 focused update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2011, (September). [Epub ahead of print].
    • (2011) J Clin Oncol
    • Azzoli, C.G.1    Temin, S.2    Aliff, T.3    Baker, S.4    Brahmer, J.5    Johnson, D.H.6
  • 3
    • 79959703683 scopus 로고    scopus 로고
    • Panel Members Metastatic non-small-cell lung cancer: consensus on pathology and molecular tests, first-line, second-line, and third-line therapy: 1st ESMO Consensus Conference in Lung Cancer; Lugano 2010
    • Felip E., Gridelli C., Baas P., Rosell R., Stahel R., Panel Members Metastatic non-small-cell lung cancer: consensus on pathology and molecular tests, first-line, second-line, and third-line therapy: 1st ESMO Consensus Conference in Lung Cancer; Lugano 2010. Ann Oncol 2011, 22:1507-1519.
    • (2011) Ann Oncol , vol.22 , pp. 1507-1519
    • Felip, E.1    Gridelli, C.2    Baas, P.3    Rosell, R.4    Stahel, R.5
  • 4
    • 84860509537 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network-Clinical Practice Guidelines in Oncology. Non-small-cell lung cancer. Version 3.2011 [last accessed 18.07.2011].
    • National Comprehensive Cancer Network-Clinical Practice Guidelines in Oncology. Non-small-cell lung cancer. Version 3.2011 [last accessed 18.07.2011]. http://www.nccn.org/.
  • 5
    • 79957730176 scopus 로고    scopus 로고
    • Treatment of advanced non-small-cell lung cancer: Italian Association of Thoracic Oncology (AIOT) clinical practice guidelines
    • de Marinis F., Rossi A., Di Maio M., Ricciardi S., Gridelli C. Treatment of advanced non-small-cell lung cancer: Italian Association of Thoracic Oncology (AIOT) clinical practice guidelines. Lung Cancer 2011, 73:1-10.
    • (2011) Lung Cancer , vol.73 , pp. 1-10
    • de Marinis, F.1    Rossi, A.2    Di Maio, M.3    Ricciardi, S.4    Gridelli, C.5
  • 6
    • 63849290363 scopus 로고    scopus 로고
    • Potential treatment option after first-line chemotherapy for advanced NSCLC: maintenance treatment or early second-line?
    • Gridelli C., Maione P., Rossi A., Ferrara M.L., Bareschino M., Schettino C., et al. Potential treatment option after first-line chemotherapy for advanced NSCLC: maintenance treatment or early second-line?. Oncologist 2009, 14:137-147.
    • (2009) Oncologist , vol.14 , pp. 137-147
    • Gridelli, C.1    Maione, P.2    Rossi, A.3    Ferrara, M.L.4    Bareschino, M.5    Schettino, C.6
  • 7
    • 59149092945 scopus 로고    scopus 로고
    • Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer
    • Fidias P.M., Dakhil S.R., Lyss A.P., Loesch D.M., Waterhouse D.M., Bromund J.L., et al. Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer. J Clin Oncol 2009, 27:591-598.
    • (2009) J Clin Oncol , vol.27 , pp. 591-598
    • Fidias, P.M.1    Dakhil, S.R.2    Lyss, A.P.3    Loesch, D.M.4    Waterhouse, D.M.5    Bromund, J.L.6
  • 9
    • 70350225538 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
    • Ciuleanu T., Brodowicz T., Zielinski C., Kim J.H., Krzakowski M., Laack E., et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet 2009, 374:1432-1440.
    • (2009) Lancet , vol.374 , pp. 1432-1440
    • Ciuleanu, T.1    Brodowicz, T.2    Zielinski, C.3    Kim, J.H.4    Krzakowski, M.5    Laack, E.6
  • 10
    • 70349092474 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care (BSC) versus placebo plus BSC: a randomized phase III study in advanced non-small cell lung cancer
    • [Suppl.; abstr CRA8000]
    • Belani C.P., Brodowicz T., Ciuleanu T., Kim J.H., Krzakowski M., Laack E., et al. Maintenance pemetrexed plus best supportive care (BSC) versus placebo plus BSC: a randomized phase III study in advanced non-small cell lung cancer. J Clin Oncol 2009, 27:18s. [Suppl.; abstr CRA8000].
    • (2009) J Clin Oncol , vol.27
    • Belani, C.P.1    Brodowicz, T.2    Ciuleanu, T.3    Kim, J.H.4    Krzakowski, M.5    Laack, E.6
  • 11
    • 15944388587 scopus 로고    scopus 로고
    • French Thoracic Oncology Collaborative Group (GCOT). Randomized study of maintenance vinorelbine in responders with advanced non-small-cell lung cancer
    • Westeel V., Quoix E., Moro-Sibilot D., Mercier M., Breton J.L., Debieuvre D., et al. French Thoracic Oncology Collaborative Group (GCOT). Randomized study of maintenance vinorelbine in responders with advanced non-small-cell lung cancer. J Natl Cancer Inst 2005, 97:499-506.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 499-506
    • Westeel, V.1    Quoix, E.2    Moro-Sibilot, D.3    Mercier, M.4    Breton, J.L.5    Debieuvre, D.6
  • 12
    • 33646485007 scopus 로고    scopus 로고
    • Central European Cooperative Oncology Group CECOG. Cisplatin and gemcitabine first-line chemotherapy followed by maintenance gemcitabine or best supportive care in advanced non-small cell lung cancer: a phase III trial
    • Brodowicz T., Krzakowski M., Zwitter M., Tzekova V., Ramlau R., Ghilezan N., et al. Central European Cooperative Oncology Group CECOG. Cisplatin and gemcitabine first-line chemotherapy followed by maintenance gemcitabine or best supportive care in advanced non-small cell lung cancer: a phase III trial. Lung Cancer 2006, 52:155-163.
    • (2006) Lung Cancer , vol.52 , pp. 155-163
    • Brodowicz, T.1    Krzakowski, M.2    Zwitter, M.3    Tzekova, V.4    Ramlau, R.5    Ghilezan, N.6
  • 13
    • 78049401119 scopus 로고    scopus 로고
    • Phase III study of maintenance gemcitabine (G) and best supportive care (BSC) versus BSC, following standard combination therapy with gemcitabine-carboplatin (G-Cb) for patients with advanced non-small cell lung cancer (NSCLC)
    • [Suppl.; abstr 7506]
    • Belani C.P., Waterhouse D.M., Ghazal H., Ramalingam S.S., Bordoni R., Greenberg R., et al. Phase III study of maintenance gemcitabine (G) and best supportive care (BSC) versus BSC, following standard combination therapy with gemcitabine-carboplatin (G-Cb) for patients with advanced non-small cell lung cancer (NSCLC). J Clin Oncol 2010, 28:15s. [Suppl.; abstr 7506].
    • (2010) J Clin Oncol , vol.28
    • Belani, C.P.1    Waterhouse, D.M.2    Ghazal, H.3    Ramalingam, S.S.4    Bordoni, R.5    Greenberg, R.6
  • 14
    • 77957042719 scopus 로고    scopus 로고
    • Maintenance with either gemcitabine or erlotinib versus observation with predefined second-line treatment after cisplatin-gemcitabine induction chemotherapy in advanced NSCLC: IFCT-GFPC 0502 phase III study
    • [Suppl.; abstr 7507]
    • Perol M., Chouaid C., Milleron B.J., Gervais R., Barlesi F., Westeel V., et al. Maintenance with either gemcitabine or erlotinib versus observation with predefined second-line treatment after cisplatin-gemcitabine induction chemotherapy in advanced NSCLC: IFCT-GFPC 0502 phase III study. J Clin Oncol 2010, 28(15s). [Suppl.; abstr 7507].
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Perol, M.1    Chouaid, C.2    Milleron, B.J.3    Gervais, R.4    Barlesi, F.5    Westeel, V.6
  • 15
    • 80052748728 scopus 로고    scopus 로고
    • PARAMOUNT: phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC)
    • [Suppl.; abstr CRA7510]
    • Paz-Ares L.G., De Marinis F., Dediu M., Thomas M., Pujol J., Bidoli P., et al. PARAMOUNT: phase III study of maintenance pemetrexed (pem) plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pem plus cisplatin for advanced nonsquamous non-small cell lung cancer (NSCLC). J Clin Oncol 2011, 29. [Suppl.; abstr CRA7510].
    • (2011) J Clin Oncol , pp. 29
    • Paz-Ares, L.G.1    De Marinis, F.2    Dediu, M.3    Thomas, M.4    Pujol, J.5    Bidoli, P.6
  • 16
    • 84860519221 scopus 로고    scopus 로고
    • Safety, resource use, and quality of life results from PARAMOUNT: A phase III study of maintenance pemetrexed plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pemetrexed-cisplatin for advanced NSCLC
    • Gridelli C., de Marinis F., Pujol J., Reck M., Ramlau R., Parente B., et al. Safety, resource use, and quality of life results from PARAMOUNT: A phase III study of maintenance pemetrexed plus best supportive care (BSC) versus placebo plus BSC immediately following induction treatment with pemetrexed-cisplatin for advanced NSCLC. Presented at 14th World Conference on Lung Cancer 2011.
    • (2011) Presented at 14th World Conference on Lung Cancer
    • Gridelli, C.1    de Marinis, F.2    Pujol, J.3    Reck, M.4    Ramlau, R.5    Parente, B.6
  • 17
    • 84863754395 scopus 로고    scopus 로고
    • AVAPERL (MO22089): final efficacy outcomes for patients with advanced non-squamous non-small cell lung cancer randomised to continuation maintenance with bevacizumab or bevacizumab+pemetrexed after first-line bevacizumab-cisplatin-pemetrexed treatment
    • [47 (Suppl. 2): abstract 34LBA]
    • Barlesi F., de Castro J., Dvornichenko V., Kim J.H., Pazzola A., Rittmeyer A., et al. AVAPERL (MO22089): final efficacy outcomes for patients with advanced non-squamous non-small cell lung cancer randomised to continuation maintenance with bevacizumab or bevacizumab+pemetrexed after first-line bevacizumab-cisplatin-pemetrexed treatment. Presented at 2011 ECCO-ESMO European Multidisciplinary Cancer Congress. Eur J Cancer 2011, [47 (Suppl. 2): abstract 34LBA].
    • (2011) Presented at 2011 ECCO-ESMO European Multidisciplinary Cancer Congress. Eur J Cancer
    • Barlesi, F.1    de Castro, J.2    Dvornichenko, V.3    Kim, J.H.4    Pazzola, A.5    Rittmeyer, A.6
  • 18
    • 77953541527 scopus 로고    scopus 로고
    • SATURN investigators. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
    • Cappuzzo F., Ciuleanu T., Stelmakh L., Cicenas S., Szczésna A., Juhász E., et al. SATURN investigators. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010, 11:521-529.
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3    Cicenas, S.4    Szczésna, A.5    Juhász, E.6
  • 19
    • 70349477817 scopus 로고    scopus 로고
    • For the ATLAS Investigators; A randomized, double-blind, placebo-controlled, phase IIIb trial (ATLAS) comparing bevacizumab (B) therapy with or without erlotinib (E) after completion of chemotherapy with B for first-line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer (NSCLC)
    • [Suppl.; abstr LBA8002]
    • Miller V.A., O'Connor P., Soh C., Kabbinavar F. for the ATLAS Investigators; A randomized, double-blind, placebo-controlled, phase IIIb trial (ATLAS) comparing bevacizumab (B) therapy with or without erlotinib (E) after completion of chemotherapy with B for first-line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer (NSCLC). J Clin Oncol 2009, 27:18s. [Suppl.; abstr LBA8002].
    • (2009) J Clin Oncol , vol.27
    • Miller, V.A.1    O'Connor, P.2    Soh, C.3    Kabbinavar, F.4
  • 20
    • 80755181069 scopus 로고    scopus 로고
    • Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer
    • Brugger W., Triller N., Blasinska-Morawiec M., Curescu S., Sakalauskas R., Manikhas G.M., et al. Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer. J Clin Oncol 2011, 29:4113-4120.
    • (2011) J Clin Oncol , vol.29 , pp. 4113-4120
    • Brugger, W.1    Triller, N.2    Blasinska-Morawiec, M.3    Curescu, S.4    Sakalauskas, R.5    Manikhas, G.M.6
  • 21
    • 84655173671 scopus 로고    scopus 로고
    • SATURN Investigators. Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line chemotherapy
    • May 24 [Epub ahead of print]
    • Coudert B., Ciuleanu T., Park K., Wu Y.L., Giaccone G., Brugger W., et al. SATURN Investigators. Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line chemotherapy. Ann Oncol 2011, May 24 [Epub ahead of print].
    • (2011) Ann Oncol
    • Coudert, B.1    Ciuleanu, T.2    Park, K.3    Wu, Y.L.4    Giaccone, G.5    Brugger, W.6
  • 22
    • 78449274913 scopus 로고    scopus 로고
    • ATLAS Investigators; Overall survival (OS) in ATLAS, a phase IIIb trial comparing bevacizumab (B) therapy with or without erlotinib (E) after completion of chemotherapy (chemo) with B for first-line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer (NSCLC)
    • [Suppl.; abstr 7526]
    • Kabbinavar F.F., Miller V.A., Johnson B.E., O'Connor P.G., Soh C. ATLAS Investigators; Overall survival (OS) in ATLAS, a phase IIIb trial comparing bevacizumab (B) therapy with or without erlotinib (E) after completion of chemotherapy (chemo) with B for first-line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer (NSCLC). J Clin Oncol 2010, 28(15s). [Suppl.; abstr 7526].
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Kabbinavar, F.F.1    Miller, V.A.2    Johnson, B.E.3    O'Connor, P.G.4    Soh, C.5
  • 23
    • 45149102984 scopus 로고    scopus 로고
    • Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
    • Kelly K., Chansky K., Gaspar L.E., Albain K.S., Jett J., Ung Y.C., et al. Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 2008, 26:2450-2456.
    • (2008) J Clin Oncol , vol.26 , pp. 2450-2456
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3    Albain, K.S.4    Jett, J.5    Ung, Y.C.6
  • 24
    • 77649203360 scopus 로고    scopus 로고
    • Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese patients with advanced non-small-cell lung cancer: results of a west Japan thoracic oncology group trial (WJTOG0203)
    • Takeda K., Hida T., Sato T., Ando M., Seto T., Satouchi M., et al. Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese patients with advanced non-small-cell lung cancer: results of a west Japan thoracic oncology group trial (WJTOG0203). J Clin Oncol 2010, 28:753-760.
    • (2010) J Clin Oncol , vol.28 , pp. 753-760
    • Takeda, K.1    Hida, T.2    Sato, T.3    Ando, M.4    Seto, T.5    Satouchi, M.6
  • 25
    • 80054731248 scopus 로고    scopus 로고
    • Efficacy, tolerability, and biomarker analyses from a phase III, randomized, placebo-controlled, parallel group study of gefitinib as maintenance therapy in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC; INFORM; C-TONG 0804)
    • [Suppl.; abstr LBA7511]
    • Zhang L., Shenglin M., Song X., Han B., Cheng Y., Huang C., et al. Efficacy, tolerability, and biomarker analyses from a phase III, randomized, placebo-controlled, parallel group study of gefitinib as maintenance therapy in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC; INFORM; C-TONG 0804). J Clin Oncol 2011, 29. [Suppl.; abstr LBA7511].
    • (2011) J Clin Oncol , pp. 29
    • Zhang, L.1    Shenglin, M.2    Song, X.3    Han, B.4    Cheng, Y.5    Huang, C.6
  • 26
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A., Gray R., Perry M.C., Brahmer J., Schiller J.H., Dowlati A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355:2542-2550.
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3    Brahmer, J.4    Schiller, J.H.5    Dowlati, A.6
  • 27
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAiL
    • [Erratum in: J Clin Oncol 2009;27:2415]
    • Reck M., von Pawel J., Zatloukal P., Ramlau R., Gorbounova V., Hirsh V., et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAiL. J Clin Oncol 2009, 27:1227-1234. [Erratum in: J Clin Oncol 2009;27:2415].
    • (2009) J Clin Oncol , vol.27 , pp. 1227-1234
    • Reck, M.1    von Pawel, J.2    Zatloukal, P.3    Ramlau, R.4    Gorbounova, V.5    Hirsh, V.6
  • 28
    • 65349116059 scopus 로고    scopus 로고
    • FLEX Study Team. Cetuximab plus chemotherapy in patients with advanced non-small cell lung cancer (FLEX): an open-label randomised phase III trial
    • Pirker R., Pereira J.R., Szczesna A., von Pawel J., Krzakowski M., Ramlau R., et al. FLEX Study Team. Cetuximab plus chemotherapy in patients with advanced non-small cell lung cancer (FLEX): an open-label randomised phase III trial. Lancet 2009, 373:1525-1531.
    • (2009) Lancet , vol.373 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3    von Pawel, J.4    Krzakowski, M.5    Ramlau, R.6
  • 29
    • 77949891126 scopus 로고    scopus 로고
    • Cetuximab and first-line taxane/carboplatin chemotherapy in advanced nonsmall-cell lung cancer: results of the randomized multicenter phase III trial BMS099
    • Lynch T.J., Patel T., Dreisbach L., McCleod M., Heim W.J., Hermann R.C., et al. Cetuximab and first-line taxane/carboplatin chemotherapy in advanced nonsmall-cell lung cancer: results of the randomized multicenter phase III trial BMS099. J Clin Oncol 2010, 28:911-917.
    • (2010) J Clin Oncol , vol.28 , pp. 911-917
    • Lynch, T.J.1    Patel, T.2    Dreisbach, L.3    McCleod, M.4    Heim, W.J.5    Hermann, R.C.6
  • 30
    • 84856579849 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) expression as a predictor of survival for first-line chemotherapy plus cetuximab in FLEX study patients with advanced non-small cell lung cancer (NSCLC)
    • [abstract]
    • Pirker R., Paz-Ares L., Eberhardt W., Krzakowski M., Störkel S., Heeger S., et al. Epidermal growth factor receptor (EGFR) expression as a predictor of survival for first-line chemotherapy plus cetuximab in FLEX study patients with advanced non-small cell lung cancer (NSCLC). WCLC 2011, [abstract].
    • (2011) WCLC
    • Pirker, R.1    Paz-Ares, L.2    Eberhardt, W.3    Krzakowski, M.4    Störkel, S.5    Heeger, S.6
  • 31
    • 33747844588 scopus 로고    scopus 로고
    • Response rate or time to progression as predictors of survival in trials of metastatic colorectal cancer or non-small-cell lung cancer: a meta-analysis
    • Johnson K.R., Ringland C., Stokes B.J., Anthony D.M., Freemantle N., Irs A., et al. Response rate or time to progression as predictors of survival in trials of metastatic colorectal cancer or non-small-cell lung cancer: a meta-analysis. Lancet Oncol 2006, 7:741-746.
    • (2006) Lancet Oncol , vol.7 , pp. 741-746
    • Johnson, K.R.1    Ringland, C.2    Stokes, B.J.3    Anthony, D.M.4    Freemantle, N.5    Irs, A.6
  • 32
    • 79960414995 scopus 로고    scopus 로고
    • Maintenance therapy with continuous or switch strategy in advanced non-small cell lung cancer: a systematic review and meta-analysis
    • Zhang X., Zang J., Xu J., Bai C., Qin Y., Liu K., et al. Maintenance therapy with continuous or switch strategy in advanced non-small cell lung cancer: a systematic review and meta-analysis. Chest 2011, 140:117-126.
    • (2011) Chest , vol.140 , pp. 117-126
    • Zhang, X.1    Zang, J.2    Xu, J.3    Bai, C.4    Qin, Y.5    Liu, K.6
  • 33
    • 84858685177 scopus 로고    scopus 로고
    • Single-agent maintenance therapy for advanced-stage non-small cell lung cancer: a meta-analysis
    • [Suppl.; abstr 7553]
    • Behera M., Owonikoko T.K., Chen Z., Kono S.A., Khuri F.R., Belani C.P., et al. Single-agent maintenance therapy for advanced-stage non-small cell lung cancer: a meta-analysis. J Clin Oncol 2011, 29. [Suppl.; abstr 7553].
    • (2011) J Clin Oncol , pp. 29
    • Behera, M.1    Owonikoko, T.K.2    Chen, Z.3    Kono, S.A.4    Khuri, F.R.5    Belani, C.P.6
  • 34
    • 84857608820 scopus 로고    scopus 로고
    • Is there a benefit to maintenance therapy after first line chemotherapy in advanced non-small cell lung cancer-a systematic review with meta-analysis. Abstract Book, 2011 European Multidisciplinary Cancer Congress: S593
    • [abstr. 9005]
    • Des Guetz G., Uzzan B., Chouahnia K., Nicolas P., Perol M., Morere J.F. Is there a benefit to maintenance therapy after first line chemotherapy in advanced non-small cell lung cancer-a systematic review with meta-analysis. Abstract Book, 2011 European Multidisciplinary Cancer Congress: S593. Eur J Cancer 2011, 47(Suppl. 1). [abstr. 9005].
    • (2011) Eur J Cancer , vol.47 , Issue.SUPPL. 1
    • Des Guetz, G.1    Uzzan, B.2    Chouahnia, K.3    Nicolas, P.4    Perol, M.5    Morere, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.