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Volumn 13, Issue 8, 2012, Pages 1385-1398

Monoclonal antibodies for the immunotherapy of solid tumours

Author keywords

Antibody dependent cell cytotoxicity (ADCC); Complementmediated lysis; Micro metastasis; Tumour associated antigen (TAA); Tumour infiltrating lymphocytes (TIL)

Indexed keywords

ADECATUMUMAB; BEVACIZUMAB; CATUMAXOMAB; CETUXIMAB; CIXUTUMUMAB; FIGITUMUMAB; HECEPTIN; IPILIMUMAB; LEXATUMUMAB; MAPATUMUMAB; MONOCLONAL ANTIBODY; PANITUMUMAB; PRITUMUMAB; TICILIMUMAB; TRASTUZUMAB; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84860520991     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920112800784844     Document Type: Article
Times cited : (9)

References (80)
  • 2
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren, L.; O'Reilly, M.; Folkman, J. Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med., 1995, 1, 149-53.
    • (1995) Nat. Med , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.2    Folkman, J.3
  • 3
    • 60849128549 scopus 로고    scopus 로고
    • Monoclonal antibodies as innovative therapeutics
    • Reichert, J.M. Monoclonal antibodies as innovative therapeutics. Curr. Pharm. Biotechnol., 2008, 9 (6), 423-30.
    • (2008) Curr. Pharm. Biotechnol , vol.9 , Issue.6 , pp. 423-430
    • Reichert, J.M.1
  • 4
    • 60849117560 scopus 로고    scopus 로고
    • Therapeutic antibodies and derivatives: From the bench to the clinic
    • Beck, A.; Wurch, T.; Corvaia, N. Therapeutic antibodies and derivatives: from the bench to the clinic. Curr. Pharm. Biotechnol., 2008, 9 (6), 421-2.
    • (2008) Curr. Pharm. Biotechnol , vol.9 , Issue.6 , pp. 421-422
    • Beck, A.1    Wurch, T.2    Corvaia, N.3
  • 6
    • 34548240159 scopus 로고    scopus 로고
    • Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer
    • Ribas, A.; Hanson, D.C.; Noe, D.A.; Millham, R.; Guyot, D.J.; Bernstein, S.H.; Canniff, P.C.; Sharma, A.; Gomez-Navarro, J. Tremelimumab (CP-675,206), a cytotoxic T lymphocyte associated antigen 4 blocking monoclonal antibody in clinical development for patients with cancer. The Oncologist, 2007, 12 (7), 873-883.
    • (2007) The Oncologist , vol.12 , Issue.7 , pp. 873-883
    • Ribas, A.1    Hanson, D.C.2    Noe, D.A.3    Millham, R.4    Guyot, D.J.5    Bernstein, S.H.6    Canniff, P.C.7    Sharma, A.8    Gomez-Navarro, J.9
  • 8
    • 0030853610 scopus 로고    scopus 로고
    • Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: The effect is manifested only at the restricted tumor-bearing stages
    • Yang, Y.F.; Zou, J.P.; Mu, J.; Wijesuriya, R.; Ono, S.; Walunas, T.; Bluestone, J.; Fujiwara, H.; Hamaoka, T. Enhanced induction of antitumor T-cell responses by cytotoxic T lymphocyte-associated molecule-4 blockade: the effect is manifested only at the restricted tumor-bearing stages. Cancer res., 1997, 57 (18), 4036-4041.
    • (1997) Cancer Res , vol.57 , Issue.18 , pp. 4036-4041
    • Yang, Y.F.1    Zou, J.P.2    Mu, J.3    Wijesuriya, R.4    Ono, S.5    Walunas, T.6    Bluestone, J.7    Fujiwara, H.8    Hamaoka, T.9
  • 9
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt, J.A.; Mayer, R.J. Systemic therapy for colorectal cancer. The New Eng. J. Med., 2005, 352 (5), 476-487.
    • (2005) The New Eng. J. Med , vol.352 , Issue.5 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 10
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: Immunoselection and immunosubversion
    • Zitvogel, L.; Tesniere, A.; Kroemer, G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nature Rev., 2006, 6 (10), 715-727.
    • (2006) Nature Rev , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 11
    • 0029134905 scopus 로고
    • Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation
    • Stewart, T.; Tsai, J.; Greyson, H.; Henderson, R.; Opelz, G. Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. Lancet, 1995, 346, 796-798.
    • (1995) Lancet , vol.346 , pp. 796-798
    • Stewart, T.1    Tsai, J.2    Greyson, H.3    Henderson, R.4    Opelz, G.5
  • 13
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • Gallucci, S.; Matzinger, P. Danger signals: SOS to the immune system. Curr. opin. immuno., 2001, 13 (1), 114-119.
    • (2001) Curr. Opin. Immuno , vol.13 , Issue.1 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 14
    • 70449375361 scopus 로고    scopus 로고
    • What's fueling the biotech engine--2008
    • Aggarwal, S. What's fueling the biotech engine--2008. Nat. biotechnol., 2009, 27 (11), 987-993.
    • (2009) Nat. Biotechnol , vol.27 , Issue.11 , pp. 987-993
    • Aggarwal, S.1
  • 15
    • 60849120154 scopus 로고    scopus 로고
    • Development and production of commercial therapeutic monoclonal antibodies in Mammalian cell expression systems: An overview of the current upstream technologies
    • Chartrain, M.; Chu, L. Development and production of commercial therapeutic monoclonal antibodies in Mammalian cell expression systems: an overview of the current upstream technologies. Curr. Pharm. Biotechnol., 2008, 9 (6), 447-467.
    • (2008) Curr. Pharm. Biotechnol , vol.9 , Issue.6 , pp. 447-467
    • Chartrain, M.1    Chu, L.2
  • 17
    • 70350732743 scopus 로고    scopus 로고
    • Antibody production branches out
    • Dove, A. Antibody production branches out. Nat. Methods, 2009, 6 (11), 851-855.
    • (2009) Nat. Methods , vol.6 , Issue.11 , pp. 851-855
    • Dove, A.1
  • 18
    • 0028130057 scopus 로고
    • Fc Receptors: Rubor redux
    • Ravetch, J. Fc Receptors: Rubor redux. Cell, 1994, 78, 553-560.
    • (1994) Cell , vol.78 , pp. 553-560
    • Ravetch, J.1
  • 19
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn, F.; Ravetch, J.V. Fcgamma receptors as regulators of immune responses. Nat. Reviews, 2008, 8 (1), 34-47.
    • (2008) Nat. Reviews , vol.8 , Issue.1 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 20
    • 84872610198 scopus 로고    scopus 로고
    • Neue Diagnose- und Therapie-Ansätze bei Tumoren
    • Gruber, R. Neue Diagnose- und Therapie-Ansätze bei Tumoren. Diagnostica Dialog, 1998, 1, 7-9.
    • (1998) Diagnostica Dialog , vol.1 , pp. 7-9
    • Gruber, R.1
  • 21
    • 0000029046 scopus 로고
    • Principles and applications of biologic therapy
    • 4th ed.; DeVita, V. T.; Hellman, S.; Rosenberg, S. A., Eds. J.B. Lippincott Co.: Philadelphia
    • Rosenberg, S.A. Principles and applications of biologic therapy. In Cancer: Principles and practice of oncology, 4th ed.; DeVita, V. T.; Hellman, S.; Rosenberg, S. A., Eds. J.B. Lippincott Co.: Philadelphia, 1993; pp 293-324.
    • (1993) Cancer: Principles and Practice of Oncology , pp. 293-324
    • Rosenberg, S.A.1
  • 22
    • 36049003710 scopus 로고    scopus 로고
    • Potential target antigens for immunotherapy identified by serological expression cloning (SEREX)
    • Jager, D. Potential target antigens for immunotherapy identified by serological expression cloning (SEREX). Methods Mol. Biol., 2007, 360, 319-326.
    • (2007) Methods Mol. Biol , vol.360 , pp. 319-326
    • Jager, D.1
  • 24
    • 0021336980 scopus 로고
    • Binding of murine immunoglobulin to human tissues after immunotherapy with anticolorectal carcinoma monoclonal antibody
    • Shen, J.-W.; Atkinson, B.; Koprowski, H.; Sears, H., Binding of murine immunoglobulin to human tissues after immunotherapy with anticolorectal carcinoma monoclonal antibody. Int J Cancer, 1984, 33, 465-468.
    • (1984) Int J Cancer , vol.33 , pp. 465-468
    • Shen, J.-W.1    Atkinson, B.2    Koprowski, H.3    Sears, H.4
  • 28
    • 0028107507 scopus 로고
    • Human Immune Response to monoclonal antibodies
    • Khazaeli, M.; Conry, R.; LoBuglio, A. Human Immune Response to monoclonal antibodies. J. Immunother., 1994, 15, 42-52.
    • (1994) J. Immunother , vol.15 , pp. 42-52
    • Khazaeli, M.1    Conry, R.2    Lobuglio, A.3
  • 30
    • 0027999767 scopus 로고
    • Anti-idiotypes and their application under autoimmune, neoplastic, and infectious conditions
    • Shoenfeld, Y.; Amital, H.; Ferrone, S.; Kennedy, R. Anti-idiotypes and their application under autoimmune, neoplastic, and infectious conditions. Int. Arch. Allergy Immmunol., 1994, 105, 211-223.
    • (1994) Int. Arch. Allergy Immmunol , vol.105 , pp. 211-223
    • Shoenfeld, Y.1    Amital, H.2    Ferrone, S.3    Kennedy, R.4
  • 32
    • 0027289121 scopus 로고
    • Survey of methods for measuring human anti-mouse antibodies
    • HAMA Survey Group
    • HAMA Survey Group, Survey of methods for measuring human anti-mouse antibodies. Clin. Chim. Acta., 1993, 215 (2), 153-163.
    • (1993) Clin. Chim. Acta , vol.215 , Issue.2 , pp. 153-163
  • 33
    • 0027081146 scopus 로고
    • Lack of T-cell immunity in humans with preexisting anti-mouse immunoglobulin reactivity
    • Conry, R. M.; Khazaeli, M. B.; LoBuglio, A. F. Lack of T-cell immunity in humans with preexisting anti-mouse immunoglobulin reactivity. Cancer Research, 1992, 52 (24), 6979-6982.
    • (1992) Cancer Research , vol.52 , Issue.24 , pp. 6979-6982
    • Conry, R.M.1    Khazaeli, M.B.2    Lobuglio, A.F.3
  • 34
    • 0028999405 scopus 로고
    • Interference by human antibodies with tumor marker assays
    • Reinsberg, J. Interference by human antibodies with tumor marker assays. Hybridoma, 1995, 14 (2), 205-208.
    • (1995) Hybridoma , vol.14 , Issue.2 , pp. 205-208
    • Reinsberg, J.1
  • 35
    • 0030610825 scopus 로고    scopus 로고
    • Value of HAMA--determination in clinical practice--an overview
    • Hasholzner, U.; Stieber, P.; Meier, W.; Lamerz, R. Value of HAMA--determination in clinical practice--an overview. Anticancer Res., 1997, 17 (4b), 3055-3058.
    • (1997) Anticancer Res , vol.17 , Issue.4 b , pp. 3055-3058
    • Hasholzner, U.1    Stieber, P.2    Meier, W.3    Lamerz, R.4
  • 36
    • 0031877466 scopus 로고    scopus 로고
    • Interferences with two-site immunoassays by human anti-mouse antibodies formed by patients treated with monoclonal antibodies: Comparison of different blocking reagents
    • Reinsberg, J. Interferences with two-site immunoassays by human anti-mouse antibodies formed by patients treated with monoclonal antibodies: comparison of different blocking reagents. Clin. Chem., 1998, 44 (8 Pt 1), 1742-1744.
    • (1998) Clin. Chem , vol.44 , Issue.8 Pt 1 , pp. 1742-1744
    • Reinsberg, J.1
  • 37
    • 0030024847 scopus 로고    scopus 로고
    • Antibody-enzyme conjugates for cancer therapy
    • Melton, R.; Sherwood, R. Antibody-enzyme conjugates for cancer therapy. J. Natl. Cancer Inst., 1996, 88, 153-165.
    • (1996) J. Natl. Cancer Inst , vol.88 , pp. 153-165
    • Melton, R.1    Sherwood, R.2
  • 38
    • 0028845205 scopus 로고
    • Overview of studies on experimental radioimmunotherapy
    • Knox, S. Overview of studies on experimental radioimmunotherapy. Canc. Res., 1995, 55, 5832s-5836s (Suppl).
    • (1995) Canc. Res , vol.55 , Issue.SUPPL.
    • Knox, S.1
  • 39
    • 0031856404 scopus 로고    scopus 로고
    • The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: Relevance for immunotherapy of carcinomas
    • Velders, M. P.; van Rhijn, C. M.; Oskam, E.; Fleuren, G. J.; Warnaar, S. O.; Litvinov, S. V. The impact of antigen density and antibody affinity on antibody-dependent cellular cytotoxicity: relevance for immunotherapy of carcinomas. British J. Canc., 1998, 78 (4), 478-483.
    • (1998) British J. Canc , vol.78 , Issue.4 , pp. 478-483
    • Velders, M.P.1    van Rhijn, C.M.2    Oskam, E.3    Fleuren, G.J.4    Warnaar, S.O.5    Litvinov, S.V.6
  • 41
    • 0028854592 scopus 로고
    • Minor human antibody response to a mouse and chimeric monoclonal antibody after a single i.v. infusion in ovarian carcinoma patients: A comparison of five assays
    • Buist, M. R.; Kenemans, P.; van Kamp, G. J.; Haisma, H. J. Minor human antibody response to a mouse and chimeric monoclonal antibody after a single i.v. infusion in ovarian carcinoma patients: a comparison of five assays. Cancer Immunol. Immunother., 1995, 40 (1), 24-30.
    • (1995) Cancer Immunol. Immunother , vol.40 , Issue.1 , pp. 24-30
    • Buist, M.R.1    Kenemans, P.2    van Kamp, G.J.3    Haisma, H.J.4
  • 42
    • 0032560552 scopus 로고    scopus 로고
    • Synthetic human antibodies and a strategy for protein engineering
    • Winter, G. Synthetic human antibodies and a strategy for protein engineering. FEBS lett., 1998, 430, 92-94.
    • (1998) FEBS Lett , vol.430 , pp. 92-94
    • Winter, G.1
  • 47
    • 0031569465 scopus 로고    scopus 로고
    • Biologic Properties of a Bispecific Single-Chain Antibody Directed Against 17-1A (EpCAM) and CD3
    • Mack, M.; Gruber, G.; Schmidt, S.; Riethmüller, G.; Kufer, P. Biologic Properties of a Bispecific Single-Chain Antibody Directed Against 17-1A (EpCAM) and CD3. J. Immunol., 1997, 158, 3965-3970.
    • (1997) J. Immunol , vol.158 , pp. 3965-3970
    • Mack, M.1    Gruber, G.2    Schmidt, S.3    Riethmüller, G.4    Kufer, P.5
  • 50
    • 65349172418 scopus 로고    scopus 로고
    • Adjuvant therapy with the monoclonal antibody Edrecolomab plus fluorouracil-based therapy does not improve overall survival of patients with stage III colon cancer
    • Fields, A. L.; Keller, A.; Schwartzberg, L.; Bernard, S.; Kardinal, C.; Cohen, A.; Schulz, J.; Eisenberg, P.; Forster, J.; Wissel, P. Adjuvant therapy with the monoclonal antibody Edrecolomab plus fluorouracil-based therapy does not improve overall survival of patients with stage III colon cancer. J. Clin. Oncol., 2009, 27 (12), 1941-1947.
    • (2009) J. Clin. Oncol , vol.27 , Issue.12 , pp. 1941-1947
    • Fields, A.L.1    Keller, A.2    Schwartzberg, L.3    Bernard, S.4    Kardinal, C.5    Cohen, A.6    Schulz, J.7    Eisenberg, P.8    Forster, J.9    Wissel, P.10
  • 51
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab--mechanism of action and use in clinical practice
    • Hudis, C. A. Trastuzumab--mechanism of action and use in clinical practice. The New Engl. J. Med., 2007, 357 (1), 39-51.
    • (2007) The New Engl. J. Med , vol.357 , Issue.1 , pp. 39-51
    • Hudis, C.A.1
  • 54
    • 67649382495 scopus 로고    scopus 로고
    • Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor
    • Freeman, D. J.; Bush, T.; Ogbagabriel, S.; Belmontes, B.; Juan, T.; Plewa, C.; Van, G.; Johnson, C.; Radinsky, R. Activity of panitumumab alone or with chemotherapy in non-small cell lung carcinoma cell lines expressing mutant epidermal growth factor receptor. Mol. Cancer Therapeutics, 2009, 8 (6), 1536-1546.
    • (2009) Mol. Cancer Therapeutics , vol.8 , Issue.6 , pp. 1536-1546
    • Freeman, D.J.1    Bush, T.2    Ogbagabriel, S.3    Belmontes, B.4    Juan, T.5    Plewa, C.6    Van, G.7    Johnson, C.8    Radinsky, R.9
  • 55
  • 57
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem, E.; Peeters, M.; Siena, S.; Humblet, Y.; Hendlisz, A.; Neyns, B.; Canon, J.L.; Van Laethem, J.L.; Maurel, J.; Richardson, G.; Wolf, M.; Amado, R.G. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J. Clin. Oncol., 2007, 25 (13), 1658-1664.
    • (2007) J. Clin. Oncol , vol.25 , Issue.13 , pp. 1658-1664
    • van Cutsem, E.1    Peeters, M.2    Siena, S.3    Humblet, Y.4    Hendlisz, A.5    Neyns, B.6    Canon, J.L.7    van Laethem, J.L.8    Maurel, J.9    Richardson, G.10    Wolf, M.11    Amado, R.G.12
  • 60
    • 38449123351 scopus 로고    scopus 로고
    • Trastuzumab for early breast cancer: Current status and future directions
    • Dinh, P.; de Azambuja, E.; Piccart-Gebhart, M.J. Trastuzumab for early breast cancer: current status and future directions. Clin. Adv. Hematol. Oncol., 2007, 5 (9), 707-717.
    • (2007) Clin. Adv. Hematol. Oncol , vol.5 , Issue.9 , pp. 707-717
    • Dinh, P.1    de Azambuja, E.2    Piccart-Gebhart, M.J.3
  • 61
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)- producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas, A.; Hurwitz, A.A.; Allison, J.P. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)- producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J. Exp. Med., 1999, 190 (3), 355-366.
    • (1999) J. Exp. Med , vol.190 , Issue.3 , pp. 355-366
    • van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 62
    • 34247231674 scopus 로고    scopus 로고
    • Drug evaluation: Adecatumumab, an engineered human anti-EpCAM antibody
    • Kirman, I.; Whelan, R.L. Drug evaluation: adecatumumab, an engineered human anti-EpCAM antibody. Curr. Opin. Mol. Ther., 2007, 9 (2), 190-196.
    • (2007) Curr. Opin. Mol. Ther , vol.9 , Issue.2 , pp. 190-196
    • Kirman, I.1    Whelan, R.L.2
  • 63
    • 33748956628 scopus 로고    scopus 로고
    • I study with adecatumumab, a human antibody directed against epithelial cell adhesion molecule, in hormone refractory prostate cancer patients
    • Oberneder, R.; Weckermann, D.; Ebner, B.; Quadt, C.; Kirchinger, P.; Raum, T.; Locher, M.; Prang, N.; Baeuerle, P.A.; Leo, E. A phase I study with adecatumumab, a human antibody directed against epithelial cell adhesion molecule, in hormone refractory prostate cancer patients. Eur. J. Cancer, 2006, 42 (15), 2530-2538.
    • (2006) Eur. J. Cancer , vol.42 , Issue.15 , pp. 2530-2538
    • Oberneder, R.1    Weckermann, D.2    Ebner, B.3    Quadt, C.4    Kirchinger, P.5    Raum, T.6    Locher, M.7    Prang, N.8    Baeuerle, P.A.9    Leo, E.A.10    Phase11
  • 66
    • 70349443573 scopus 로고    scopus 로고
    • Development of the monoclonal antibody figitumumab, targeting the insulin-like growth factor-1 receptor, for the treatment of patients with non-small-cell lung cancer
    • Gualberto, A.; Karp, D.D. Development of the monoclonal antibody figitumumab, targeting the insulin-like growth factor-1 receptor, for the treatment of patients with non-small-cell lung cancer. Clin. Lung Cancer, 2009, 10 (4), 273-280.
    • (2009) Clin. Lung Cancer , vol.10 , Issue.4 , pp. 273-280
    • Gualberto, A.1    Karp, D.D.2
  • 68
    • 66349091290 scopus 로고    scopus 로고
    • Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer
    • Karp, D.D.; Paz-Ares, L.G.; Novello, S.; Haluska, P.; Garland, L.; Cardenal, F.; Blakely, L.J.; Eisenberg, P.D.; Langer, C.J.; Blumenschein, G. Jr.; Johnson, F.M.; Green, S.; Gualberto, A. Phase II study of the anti-insulin-like growth factor type 1 receptor antibody CP-751,871 in combination with paclitaxel and carboplatin in previously untreated, locally advanced, or metastatic non-small-cell lung cancer. J. Clin. Oncol., 2009, 27 (15), 2516-2522.
    • (2009) J. Clin. Oncol , vol.27 , Issue.15 , pp. 2516-2522
    • Karp, D.D.1    Paz-Ares, L.G.2    Novello, S.3    Haluska, P.4    Garland, L.5    Cardenal, F.6    Blakely, L.J.7    Eisenberg, P.D.8    Langer, C.J.9    Blumenschein Jr., G.10    Johnson, F.M.11    Green, S.12    Gualberto, A.13
  • 69
    • 72449141229 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors
    • Wakelee, H.A.; Patnaik, A.; Sikic, B.I.; Mita, M.; Fox, N.L.; Miceli, R.; Ullrich, S.J.; Fisher, G.A.; Tolcher, A.W. Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors. Ann. Oncol., 2010, 21(2):376-381
    • (2010) Ann. Oncol , vol.21 , Issue.2 , pp. 376-381
    • Wakelee, H.A.1    Patnaik, A.2    Sikic, B.I.3    Mita, M.4    Fox, N.L.5    Miceli, R.6    Ullrich, S.J.7    Fisher, G.A.8    Tolcher, A.W.9
  • 71
    • 75149146510 scopus 로고    scopus 로고
    • Summary analysis of the pre-clinical and clinical results of brain tumor patients treated with pritumumab
    • Glassy, M.C.; Hagiwara, H. Summary analysis of the pre-clinical and clinical results of brain tumor patients treated with pritumumab. Human Antibodies, 2009, 18 (4), 127-137.
    • (2009) Human Antibodies , vol.18 , Issue.4 , pp. 127-137
    • Glassy, M.C.1    Hagiwara, H.2
  • 73
    • 32944482229 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics in oncology therapeutic antibody development
    • Yan, L.; Beckman, R.A. Pharmacogenetics and pharmacogenomics in oncology therapeutic antibody development. BioTechniques, 2005, 39 (4), 565-568.
    • (2005) BioTechniques , vol.39 , Issue.4 , pp. 565-568
    • Yan, L.1    Beckman, R.A.2
  • 75
    • 0034657595 scopus 로고    scopus 로고
    • Prognostic significance of an increased number of micrometastatic tumor cells in the bone marrow of patients with first recurrence of breast carcinoma
    • Janni, W.; Gastroph, S.; Hepp, F.; Kentenich, C.; Rjosk, D.; Schindlbeck, C.; Dimpfl, T.; Sommer, H.; Braun, S. Prognostic significance of an increased number of micrometastatic tumor cells in the bone marrow of patients with first recurrence of breast carcinoma. Cancer, 2000, 88 (10), 2252-2259.
    • (2000) Cancer , vol.88 , Issue.10 , pp. 2252-2259
    • Janni, W.1    Gastroph, S.2    Hepp, F.3    Kentenich, C.4    Rjosk, D.5    Schindlbeck, C.6    Dimpfl, T.7    Sommer, H.8    Braun, S.9
  • 76
    • 0023739306 scopus 로고
    • Enhanced cytotoxicity against colon carcinoma by combinantions of noncompeting monoclonal antibodies to the 17-1A antigen
    • Fogler, W.E.; Klinger, M.R.; Abraham, K.G.; Gottlinger, H.G.; Riethmüller, G.; Daddona, P.E. Enhanced cytotoxicity against colon carcinoma by combinantions of noncompeting monoclonal antibodies to the 17-1A antigen. Cancer Res., 1988, 48, 6303-6308.
    • (1988) Cancer Res , vol.48 , pp. 6303-6308
    • Fogler, W.E.1    Klinger, M.R.2    Abraham, K.G.3    Gottlinger, H.G.4    Riethmüller, G.5    Daddona, P.E.6
  • 77
    • 0029114244 scopus 로고
    • Phase II Trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rh-M-CSF) in patients with metastatic gastrointesinal cancer
    • Saleh, M.; Khazaeli, M.; Wheeler, R.; Bucy, R.; Liu, T.; Everson, M.; Munn, D.; Schlom, J.; LoBuglio, A. Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rh-M-CSF) in patients with metastatic gastrointesinal cancer. Cancer Res., 1995, 55, 4330-4346.
    • (1995) Cancer Res , vol.55 , pp. 4330-4346
    • Saleh, M.1    Khazaeli, M.2    Wheeler, R.3    Bucy, R.4    Liu, T.5    Everson, M.6    Munn, D.7    Schlom, J.8    Lobuglio, A.9
  • 79
    • 58849085569 scopus 로고    scopus 로고
    • BiTE: Teaching antibodies to engage T-cells for cancer therapy
    • Baeuerle, P.A.; Kufer, P.; Bargou, R. BiTE: Teaching antibodies to engage T-cells for cancer therapy. Curr. Opin. Molecular Ther., 2009, 11 (1), 22-30.
    • (2009) Curr. Opin. Molecular Ther , vol.11 , Issue.1 , pp. 22-30
    • Baeuerle, P.A.1    Kufer, P.2    Bargou, R.3
  • 80
    • 68449086890 scopus 로고    scopus 로고
    • Immunotherapy of lymphoma and leukemia with Tcell engaging BiTE antibody blinatumomab
    • Nagorsen, D.; Bargou, R.; Ruttinger, D.; Kufer, P.; Baeuerle, P. A.; Zugmaier, G. Immunotherapy of lymphoma and leukemia with Tcell engaging BiTE antibody blinatumomab. Leukemia & Lymphoma, 2009, 50 (6), 886-891.
    • (2009) Leukemia & Lymphoma , vol.50 , Issue.6 , pp. 886-891
    • Nagorsen, D.1    Bargou, R.2    Ruttinger, D.3    Kufer, P.4    Baeuerle, P.A.5    Zugmaier, G.6


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