Identification of the HSPB4/TLR2/NF-κB axis in macrophage as a therapeutic target for sterile inflammation of the cornea

EMBO Molecular Medicine

Volumn 4, Issue 5, 2012, Pages 435-448

  Oh, Joo Youn ^a,c   Choi, Hosoon ^a   Lee, Ryang Hwa ^a   Roddy, Gavin W ^a   Ylöstalo, Joni H ^a   Wawrousek, Eric ^b   Prockop, Darwin J ^a  

^a SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c Seoul National University Hospital   (South Korea)

Author keywords

Cornea; HSPB4; Inflammation; Macrophage; Toll like receptor 2

Indexed keywords

ANTIBODY; BETA ACTIN; HEAT SHOCK PROTEIN; HERMES ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN; PROTEIN HSPB4; SECRETONEURIN; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA STIMULATED GENE PROTEIN 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL BURN; CONTROLLED STUDY; CORNEA INJURY; DRY EYE; HUMAN; HUMAN CELL; KERATINOCYTE; KERATITIS; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

ANIMALS; CORNEA; CRYSTALLINS; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; KERATITIS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NEUTROPHILS; NF-KAPPA B; RATS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2;

EID: 84860520943     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201200221     Document Type: Article

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