Role of IncHI2 plasmids harbouring bla VIM-1, bla CTX-M-9, aac(6′)-Ib and qnrA genes in the spread of multiresistant Enterobacter cloacae and Klebsiella pneumoniae strains in different units at Hospital Vall d'Hebron, Barcelona, Spain

International Journal of Antimicrobial Agents

Volumn 39, Issue 6, 2012, Pages 514-517

  Coelho, A ^a,b   Piedra Carrasco, N ^a,b   Bartolome R ^a,b   Quintero Zarate, J N ^a,b   Larrosa, N ^a,b   Cornejo Sanchez T ^a   Prats, G ^a,b   Garcillan Barcia M P ^c   De La Cruz, F ^c   Gonzalez Lopez J J ^a,b  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Dissemination; IncHI2 plasmid; Multiresistant; VIM 1

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE VIM 1; CEFOTAXIME; PLASMID DNA; RIFAMPICIN; UNCLASSIFIED DRUG;

AAC(6') IB GENE; ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BLACTX M 9 GENE; BLACTX M GENE; BLAIMP GENE; BLANDM GENE; BLAVIM 1 GENE; CONFERENCE PAPER; CONTROLLED STUDY; ENTEROBACTER CLOACAE; GENE CLUSTER; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC SCREENING; INCHI2 PLASMID; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE; MOLECULAR CLONING; MOLECULAR EPIDEMIOLOGY; MULTIDRUG RESISTANCE; NONHUMAN; PLASMID; PRIORITY JOURNAL; QNRA GENE; QNRB GENE; QNRS GENE; SPAIN;

BETA-LACTAMASES; CROSS INFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI PROTEINS; HUMANS; INTENSIVE CARE UNITS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MULTILOCUS SEQUENCE TYPING; PLASMIDS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SPAIN;

EID: 84860464544     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.01.006     Document Type: Conference Paper

References (19)

1. K. Miki, H. Takegawa, M. Etoh, M. Hayashi, T. Haruta, and K. Yamane First outbreak report of VIM-1 metallo-β-lactamase producing Pseudomonas aeruginosa in Japan Kansenshogaku Zasshi 84 2010 721 726
2. J. Oteo, J.L. Hernández-Almaraz, J. Gil-Antón, A. Vindel, S. Fernández, and V. Bautista Outbreak of VIM-1-carbapenemase-producing Enterobacter cloacae in a pediatric intensive care unit Pediatr Infect Dis J 29 2010 1144 1146
3. J. Merlino, H.W. Stokes, E.Y. Cheong, and T. Gottlieb First clinical case of a locally acquired carbapenem-resistant VIM-1 metallo-β-lactamase in Pseudomonas aeruginosa in Australia Med J Aust 191 2009 289
4. I. Yildirim, M. Ceyhan, D. Gur, C. Mugnaioli, and G.M. Rossolini First detection of VIM-1 type metallo-β-lactamase in a multidrug-resistant Klebsiella pneumoniae clinical isolate from Turkey also producing the CTX-M-15 extended-spectrum β-lactamase J Chemother 19 2007 467 468 (Pubitemid 47236530)
5. VIM-1 gene associated with different Tn402 variants, mercury transposons, and conjugative plasmids in Enterobacteriaceae and Pseudomonas aeruginosa Antimicrob Agents Chemother 54 2010 320 327
6. V. Miriagou, E. Tzelepi, G.L. Daikos, P.T. Tassios, and L.S. Tzouvelekis Panresistance in VIM-1-producing Klebsiella pneumoniae J Antimicrob Chemother 55 2005 810 811
7. VIM-1-carrying integron In-e541 Int J Antimicrob Agents 32 2008 540 541
8. VIM-1-positive Klebsiella pneumoniae in Athens, Greece: a prospective survey J Antimicrob Chemother 61 2008 59 63
9. A. Poulou, N. Spanakis, S. Pournaras, V. Pitiriga, K. Ranellou, and F. Markou Recurrent healthcare-associated community-onset infections due to Klebsiella pneumoniae producing VIM-1 metallo-β-lactamase J Antimicrob Chemother 65 2010 2538 2542
10. CTX-M genes and the qnr determinant in Enterobacter cloacae, Klebsiella pneumoniae and Klebsiella oxytoca isolates J Antimicrob Chemother 65 2010 661 665
11. M.T. Tortola, S. Lavilla, E. Miró, J.J. González, N. Larrosa, and M. Sabaté First detection of a carbapenem-hydrolyzing metalloenzyme in two Enterobacteriaceae isolates in Spain Antimicrob Agents Chemother 49 2005 3492 3494 (Pubitemid 41060602)
12. CTX-M genes in Enterobacteriaceae APMIS 115 2007 1400 1408
13. A. Coelho, B. Mirelis, C. Alonso-Tarrés, M. Nieves Larrosa, E. Miró, and R. Clivillé Abad Detection of three stable genetic clones of CTX-M-15-producing Klebsiella pneumoniae in the Barcelona metropolitan area, Spain J Antimicrob Chemother 64 2009 862 864
14. A. Coelho, J.J. Gonzàlez-Lòpez, E. Miró, C. Alonso-Tarrés, B. Mirelis, and M.N. Larrosa Characterisation of the CTX-M-15-encoding gene in Klebsiella pneumoniae strains from the Barcelona metropolitan area: plasmid diversity and chromosomal integration Int J Antimicrob Agents 36 2010 73 78
15. A. García-Fernández, and A. Carattoli Plasmid double locus sequence typing for IncHI2 plasmids, a subtyping scheme for the characterization of IncHI2 plasmids carrying extended-spectrum β-lactamase and quinolone resistance genes J Antimicrob Chemother 65 2010 1155 1161
16. M.P. Garcillán-Barcia, A. Alvarado, and F. de la Cruz Identification of bacterial plasmids based on mobility and plasmid population biology FEMS Microbiol Rev 35 2011 936 956
17. L. Sorlí, E. Miró, C. Segura, F. Navarro, S. Grau, and M. Salvado Intra- and inter-species spread of carbapenemase genes in a non-hospitalized patient Eur J Clin Microbiol Infect Dis 30 2011 1551 1555
18. R. Aschbacher, L. Pagani, M. Doumith, R. Pike, N. Woodford, and G. Spoladore Metallo-β-lactamases among Enterobacteriaceae from routine samples in an Italian tertiary-care hospital and long-term care facilities during 2008 Clin Microbiol Infect 17 2011 181 189
19. O. Samuelsen, M.A. Toleman, V. Hasseltvedt, K. Fuursted, T.M. Leegaard, and T.R. Walsh Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance Clin Microbiol Infect 17 2011 1811 1816