Cytokine mapping in cerebrospinal fluid and blood in multiple sclerosis patients without oligoclonal bands

Multiple Sclerosis Journal

Volumn 18, Issue 5, 2012, Pages 669-673

  Vrethem, M ^a   Kvarnstrom M ^a   Stenstam, J ^a   Cassel, P ^a   Gustafsson, M ^a   Landtblom, A M ^a,b   Ernerudh, J ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b Motala General Hospital   (Sweden)

Author keywords

cerebrospinal fluid; cytokines; multiple sclerosis; oligoclonal bands

Indexed keywords

BETA INTERFERON; CD14 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; OLIGOCLONAL BAND; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL;

EID: 84860462190     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458511424903     Document Type: Article

References (10)

1. McLean BN, Luxton RW, Thompson EJ. A study of immunoglobulin G in the cerebrospinal fluid of 1007 patients with suspected neurological disease using isoelectric focusing and the Log IgG-Index. A comparison and diagnostic applications. Brain. 1990 ; 113: 1269-1289
2. Luque FA, Jaffe SL. Cerebrospinal fluid analysis in multiple sclerosis. Int Rev Neurobiol. 2007 ; 79: 341-356
3. Link H, Huang YM. Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness. J Neuroimmunol. 2006 ; 180: 17-28
4. McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol. 2007 ; 8: 913-919
5. Ukkonen M, Wu K, Reipert B, Dastidar P, Elovaara I. Cell surface adhesion molecules and cytokine profiles in primary progressive multiple sclerosis. Mult Scler. 2007 ; 13: 701-715
6. Imrell K, Landtblom AM, Hillert J, Masterman T. Multiple sclerosis with and without CSF bands: clinically indistinguishable but immunogenetically distinct. Neurology. 2006 ; 67: 1062-1064
7. McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001 ; 50: 121-127
8. Öhman S, Forsberg P, Nelson N, Vrethem M. An improved formula for the judgement of intrathecally produced IgG in the presence of blood brain barrier damage. Clin Chim Acta. 1989 ; 181: 265-272
9. Hagman S, Raunio M, Rossi M, Dastidar P, Elovaara I. Disease-associated inflammatory biomarker profiles in blood in different subtypes of multiple sclerosis: Prospective clinical and MRI follow-up study. J Neuroimmunol. 2011 ; 234: 141-147
10. Maimone D, Gregory S, Arnason BG, Reder AT. Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis. J Neuroimmunol. 1991 ; 32: 67-74