Perturbation of the endothelial glycocalyx in post cardiac arrest syndrome

Resuscitation

Volumn 83, Issue 6, 2012, Pages 715-720

  Grundmann, Sebastian ^a   Fink, Katrin ^a   Rabadzhieva, Lyubomira ^a   Bourgeois, Natascha ^a   Schwab, Tilmann ^a   Moser, Martin ^a   Bode, Christoph ^a   Busch, Hans Joerg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cardiac arrest; Glycocalyx; Post cardiac arrest syndrome; Post resuscitation care

Indexed keywords

ANTITHROMBIN III; HEPARAN SULFATE; HYALURONIC ACID; HYPERTENSIVE AGENT; STATIN; SYNDECAN 1;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; ENDOTHELIUM CELL; FEMALE; GLYCOCALYX; HEART ARREST; HEMODYNAMIC PARAMETERS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MEDICAL RECORD; PATHOPHYSIOLOGY; POST CARDIAC ARREST SYNDROME; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESUSCITATION; SURVIVAL; SURVIVOR;

AGED; BLOOD PROTEINS; ENDOTHELIUM, VASCULAR; FEMALE; GLYCOCALYX; HEART ARREST; HEPARITIN SULFATE; HUMANS; HYALURONIC ACID; MALE; SYNDECAN-1;

EID: 84860445611     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.01.028     Document Type: Article

References (24)

1. Strauss M., Gitt A.K., Becker T., et al. Prehospital cardiac arrest: a marker for higher mortality in patients with acute myocardial infarction and moderately reduced left ventricular function: results from the MITRA plus registry. Clin Res Cardiol 2008, 97:748-752.
2. Neumar R.W., Nolan J.P., Adrie C., et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, Inter American Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation 2008, 118:2452-2483.
3. Dokken B.B., Hilwig W.R., Teachey M.K., et al. Glucagon-like peptide-1 (GLP-1) attenuates post-resuscitation myocardial microcirculatory dysfunction. Resuscitation 2010, 81:755-760.
4. Fink K., Schwarz M., Feldbrugge L., et al. Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation. Crit Care 2010, 14:R104.
5. Adrie C., Adib-Conquy M., Laurent I., et al. Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome. Circulation 2002, 106:562-568.
6. Chappell D., Westphal M., Jacob M. The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness. Curr Opin Anaesthesiol 2009, 22:155-162.
7. Van Teeffelen J.W., Brands J., Stroes E.S., Vink H. Endothelial glycocalyx: sweet shield of blood vessels. Trends Cardiovasc Med 2007, 17:101-105.
8. Reitsma S., Slaaf D.W., Vink H., van Zandvoort M.A., oude Egbrink M.G. The endothelial glycocalyx: composition, functions, and visualization. Pflugers Arch 2007, 454:345-359.
9. Mulivor A.W., Lipowsky H.H. Inflammation- and ischemia-induced shedding of venular glycocalyx. Am J Physiol Heart Circ Physiol 2004, 286:H1672-H1680.
10. Nieuwdorp M., Meuwese M.C., Vink H., Hoekstra J.B., Kastelein J.J., Stroes E.S. The endothelial glycocalyx: a potential barrier between health and vascular disease. Curr Opin Lipidol 2005, 16:507-511.
11. Johansson P.I., Stensballe J., Rasmussen L.S., Ostrowski S.R. A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis, and increased mortality in trauma patients. Ann Surg 2011, 254:194-200.
12. Nieuwdorp M., Meuwese M.C., Mooij H.L., et al. Tumor necrosis factor-alpha inhibition protects against endotoxin-induced endothelial glycocalyx perturbation. Atherosclerosis 2009, 202:296-303.
13. Chappell D., Hofmann-Kiefer K., Jacob M., et al. TNF-alpha induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin. Basic Res Cardiol 2009, 104:78-89.
14. Chappell D., Jacob M., Hofmann-Kiefer K., et al. Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion. Cardiovasc Res 2009, 83:388-396.
15. Danielli J.F. Capillary permeability and oedema in the perfused frog. J Physiol 1940, 98:109-129.
16. van den Berg B.M., Vink H., Spaan J.A. The endothelial glycocalyx protects against myocardial edema. Circ Res 2003, 92:592-594.
17. Becker B.F., Chappell D., Bruegger D., Annecke T., Jacob M. Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potential. Cardiovasc Res 2010, 87:300-310.
18. Mochizuki S., Vink H., Hiramatsu O., et al. Role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release. Am J Physiol Heart Circ Physiol 2003, 285:H722-H726.
19. Grundmann S., Schirmer S.H., Hekking L.H., et al. Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis. J Cell Mol Med 2009, 13:3463-3474.
20. Rehm M., Bruegger D., Christ F., et al. Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia. Circulation 2007, 116:1896-1906.
21. Bruegger D., Schwartz L., Chappell D., et al. Release of atrial natriuretic peptide precedes shedding of the endothelial glycocalyx equally in patients undergoing on- and off-pump coronary artery bypass surgery. Basic Res Cardiol 2011, 106:1111-1121.
22. Nelson A., Berkestedt I., Schmidtchen A., Ljunggren L., Bodelsson M. Increased levels of glycosaminoglycans during septic shock: relation to mortality and the antibacterial actions of plasma. Shock (Augusta, GA) 2008, 30:623-627.
23. Pal N., Kertai M.D., Lakshminarasimhachar A., Avidan M.S. Pharmacology and clinical applications of human recombinant antithrombin. Expert Opin Biol Ther 2010, 10:1155-1168.
24. Meybohm P., Gruenewald M., Zacharowski K.D., et al. Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation. Crit Care 2010, 14:R21.