A standardized template for clinical studies in preterm birth

Reproductive Sciences

Volumn 19, Issue 5, 2012, Pages 474-482

  Myatt, Leslie ^a   Eschenbach, David A ^b   Lye, Stephen J ^c   Mesiano, Sam ^d   Murtha, Amy P ^e   Williams, Scott M ^f   Pennell, Craig E ^g  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

hemorrhage; infection; phenotypes; preterm birth; stress

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; DNA; GLUCOCORTICOID; RNA;

ARTICLE; BLEEDING; BODY MASS; CESAREAN SECTION; CLINICAL PROTOCOL; CLINICAL RESEARCH; FETUS ECHOGRAPHY; FETUS LUNG MATURATION; GESTATIONAL AGE; HUMAN; IATROGENIC DISEASE; INFECTION; INTRAUTERINE GROWTH RETARDATION; LABOR; OBESITY; OUTCOMES RESEARCH; PHENOTYPE; PREGNANCY; PREMATURE LABOR; PRENATAL CARE; PRIORITY JOURNAL; SEX DIFFERENCE; STANDARD; STRESS; UTERINE CERVIX DILATATION;

BIOMEDICAL RESEARCH; FEMALE; GESTATIONAL AGE; GLUCOCORTICOIDS; HUMANS; INFANT, NEWBORN; INFECTION; MALE; OBESITY; PHENOTYPE; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY, MULTIPLE; PREMATURE BIRTH; RESEARCH DESIGN; SEX FACTORS; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL; UTERINE CERVICAL DISEASES; UTERINE DISEASES; UTERINE HEMORRHAGE;

EID: 84860434648     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719111426602     Document Type: Article

References (76)

1. Beck S, Wojdyla D, Say L, et al. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ. 2010 ; 88 (1). 31-38
2. Lawn JE, Gravett MG, Nunes TM, Rubens CE, Stanton C. Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data. BMC Pregnancy Childbirth. 2010 ; 10 (suppl 1). S1
3. Martin JA, Kochanek KD, Strobino DM, Guyer B, MacDorman MF. Annual summary of vital statistics - 2003. Pediatrics. 2005 ; 115 (3). 619-634 (Pubitemid 43373022)
4. Damus K. Prevention of preterm birth: a renewed national priority. Curr Opin Obstet Gynecol. 2008 ; 20 (6). 590-596
5. Barker DJ. The developmental origins of adult disease. J Am Coll Nutr. 2004 ; 23 (6 suppl). 588S - 595S (Pubitemid 40096746)
6. Petrini JR, Dias T, McCormick MC, Massolo ML, Green NS, Escobar GJ. Increased risk of adverse neurological development for late preterm infants. J Pediatr. 2009 ; 154 (2). 169-176
7. Bhattacharya S, Raja EA, Mirazo ER, Campbell DM, Lee AJ, Norman JE. Inherited predisposition to spontaneous preterm delivery. Obstet Gynecol. 2010 ; 115 (6). 1125-1133
8. Boyd HA, Poulsen G, Wohlfahrt J, Murray JC, Feenstra B, Melbye M. Maternal contributions to preterm delivery. Am J Epidemiol. 2009 ; 170 (11). 1358-1364
9. Porter TF, Fraser AM, Hunter CY, Ward RH, Varner MW. The risk of preterm birth across generations. Obstet Gynecol. 1997 ; 90 (1). 63-67 (Pubitemid 27272958)
10. Svensson AC, Sandin S, Cnattingius S, et al. Maternal effects for preterm birth: a genetic epidemiologic study of 630,000 families. Am J Epidemiol. 2009 ; 170 (11). 1365-1372
11. Selling KE, Carstensen J, Finnstrom O, Sydsjo G. Intergenerational effects of preterm birth and reduced intrauterine growth: a population-based study of Swedish mother-offspring pairs. BJOG. 2006 ; 113 (4). 430-440
12. Weinberg CR, Shi M. The genetics of preterm birth: using what we know to design better association studies. Am J Epidemiol. 2009 ; 170 (11). 1373-1381
13. Mercer BM, Goldenberg RL, Moawad AH, et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. National institute of child health and human development maternal-fetal medicine units network. Am J Obstet Gynecol. 1999 ; 181 (5 pt 1). 1216-1221
14. Lang JM, Lieberman E, Cohen A. A comparison of risk factors for preterm labor and term small-for-gestational-age birth. Epidemiology. 1996 ; 7 (4). 369-376
15. Little J. Invited commentary: maternal effects in preterm birth - effects of maternal genotype, mitochondrial DNA, imprinting, or environment?. Am J Epidemiol. 2009 ; 170 (11). 1382-1385
16. Plunkett J, Feitosa MF, Trusgnich M, et al. Mother's genome or maternally-inherited genes acting in the fetus influence gestational age in familial preterm birth. Hum Hered. 2009 ; 68 (3). 209-219
17. Anum EA, Springel EH, Shriver MD, Strauss JF. Genetic contributions to disparities in preterm birth. Pediatr Res. 2009 ; 65 (1). 1-9
18. Velez DR, Fortunato SJ, Williams SM, Menon R. Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth. Hum Mol Genet. 2008 ; 17 (11). 1619-1630 (Pubitemid 351737166)
19. Velez DR, Fortunato SJ, Thorsen P, Lombardi SJ, Williams SM, Menon R. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. PLoS One. 2008 ; 3 (9). e3283
20. Ryckman KK, Morken NH, White MJ, et al. Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. PLoS One. 2010 ; 5 (2). e9040
21. Menon R. Race and genetics in understanding the complexities of preterm birth. Expert Rev Obstet Gynecol. 2009 ; 4 (6). 695-704
22. Nguyen TH, Larsen T, Engholm G, Moller H. Evaluation of ultrasound-estimated date of delivery in 17,450 spontaneous singleton births: do we need to modify Naegele's rule?. Ultrasound Obstet Gynecol. 1999 ; 14 (1). 23-28 (Pubitemid 29410490)
23. The Prevention of Perinatal Mortality and Morbidity. WHO Technical Report Series. Switzerland: Geneva ; 1970 :
24. Bowen JM, Chamley L, Keelan JA, Mitchell MD. Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition. Placenta. 2002 ; 23 (4). 257-273 (Pubitemid 41348518)
25. Kelly RW. Inflammatory mediators and parturition. Rev Reprod. 1996 ; 1 (2). 89-96 (Pubitemid 126664711)
26. Romero R, Gomez R, Ghezzi F, et al. A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition. Am J Obstet Gynecol. 1998 ; 179 (1). 186-193 (Pubitemid 28394494)
27. Romero R, Gotsch F, Pineles B, Kusanovic JP. Inflammation in pregnancy: its roles in reproductive physiology, obstetrical complications, and fetal injury. Nutr Rev. 2007 ; 65 (12 pt 2). S194-202
28. Goldenberg RL, Hauth JC, Andrews WW. Intrauterine infection and preterm delivery. N Engl J Med. 2000 ; 342 (20). 1500-1507 (Pubitemid 30318275)
29. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008 ; 371 (9606). 75-84
30. Lee SE, Romero R, Park CW, Jun JK, Yoon BH. The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency. Am J Obstet Gynecol. 2008 ; 198 (6). e631 - e638
31. Yoon BH, Romero R, Moon JB, et al. Clinical significance of intra-amniotic inflammation in patients with preterm labor and intact membranes. Am J Obstet Gynecol. 2001 ; 185 (5). 1130-1136 (Pubitemid 33097376)
32. Boggess KA. Pathophysiology of preterm birth: emerging concepts of maternal infection. Clin Perinatol. 2005 ; 32 (3). 561-569 (Pubitemid 41111991)
33. Klein LL, Gibbs RS. Infection and preterm birth. Obstet Gynecol Clin North Am. 2005 ; 32 (3). 397-410 (Pubitemid 41206560)
34. Park CW, Moon KC, Park JS, Jun JK, Romero R, Yoon BH. The involvement of human amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications. Placenta. 2009 ; 30 (1). 56-61
35. DiGiulio DB, Romero R, Amogan HP, et al. Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation. PLoS One. 2008 ; 3 (8). e3056
36. Hillier SL, Witkin SS, Krohn MA, Watts DH, Kiviat NB, Eschenbach DA. The relationship of amniotic fluid cytokines and preterm delivery, amniotic fluid infection, histologic chorioamnionitis, and chorioamnion infection. Obstet Gynecol. 1993 ; 81 (6). 941-948 (Pubitemid 23168738)
37. Adams Waldorf KM, Rubens CE, Gravett MG. Use of nonhuman primate models to investigate mechanisms of infection-associated preterm birth. BJOG. 2011 ; 118 (2). 136-144
38. Gravett MG, Adams KM, Sadowsky DW, et al. Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model. Am J Obstet Gynecol. 2007 ; 197 (5). e511 - e518
39. Redline RW. Placental pathology: a systematic approach with clinical correlations. Placenta. 2008 ; 29 (suppl A). S86 - S91
40. Gravett MG, Novy MJ, Rosenfeld RG, et al. Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers. JAMA. 2004 ; 292 (4). 462-469 (Pubitemid 38988955)
41. Fichorova RN, Onderdonk AB, Yamamoto H, et al. Maternal microbe-specific modulation of inflammatory response in extremely low-gestational-age newborns. MBio. 2011 ; 2 (1). e00280 - e00210
42. Yoon BH, Romero R, Park JS, et al. The relationship among inflammatory lesions of the umbilical cord (funisitis), umbilical cord plasma interleukin 6 concentration, amniotic fluid infection, and neonatal sepsis. Am J Obstet Gynecol. 2000 ; 183 (5). 1124-1129
43. Murtha AP, Sinclair T, Hauser ER, Swamy GK, Herbert WN, Heine RP. Maternal serum cytokines in preterm premature rupture of membranes. Obstet Gynecol. 2007 ; 109 (1). 121-127 (Pubitemid 46043194)
44. Gibbs RS, Duff P. Progress in pathogenesis and management of clinical intraamniotic infection. Am J Obstet Gynecol. 1991 ; 164 (5 pt 1). 1317-1326
45. Shynlova O, Kwong R, Lye SJ. Mechanical stretch regulates hypertrophic phenotype of the myometrium during pregnancy. Reproduction. 2010 ; 139 (1). 247-253
46. Lye SJ, Mitchell J, Nashman N, et al. Role of mechanical signals in the onset of term and preterm labor. Front Horm Res. 2001 ; 27: 165-178 (Pubitemid 33816371)
47. Gardner MO, Goldenberg RL, Cliver SP, Tucker JM, Nelson KG, Copper RL. The origin and outcome of preterm twin pregnancies. Obstet Gynecol. 1995 ; 85 (4). 553-557
48. Shynlova O, Williams SJ, Draper H, White BG, MacPhee DJ, Lye SJ. Uterine stretch regulates temporal and spatial expression of fibronectin protein and its alpha 5 integrin receptor in myometrium of unilaterally pregnant rats. Biol Reprod. 2007 ; 77 (5). 880-888 (Pubitemid 350014177)
49. Elovitz MA, Baron J, Phillippe M. The role of thrombin in preterm parturition. Am J Obstet Gynecol. 2001 ; 185 (5). 1059-1063 (Pubitemid 33097363)
50. Chaiworapongsa T, Espinoza J, Yoshimatsu J, et al. Activation of coagulation system in preterm labor and preterm premature rupture of membranes. J Matern Fetal Neonatal Med. 2002 ; 11 (6). 368-373 (Pubitemid 34836886)
51. Rosen T, Kuczynski E, O'Neill LM, Funai EF, Lockwood CJ. Plasma levels of thrombin-antithrombin complexes predict preterm premature rupture of the fetal membranes. J Matern Fetal Med. 2001 ; 10 (5). 297-300
52. Elovitz MA, Ascher-Landsberg J, Saunders T, Phillippe M. The mechanisms underlying the stimulatory effects of thrombin on myometrial smooth muscle. Am J Obstet Gynecol. 2000 ; 183 (3). 674-681
53. Moore RM, Schatz F, Kumar D, et al. Alpha-lipoic acid inhibits thrombin-induced fetal membrane weakening in vitro. Placenta. 2010 ; 31 (10). 886-892
54. Owen J, Iams JD. What we have learned about cervical ultrasound. Semin Perinatol. 2003 ; 27 (3). 194-203 (Pubitemid 36828956)
55. Hobel C, Culhane J. Role of psychosocial and nutritional stress on poor pregnancy outcome. J Nutr. 2003 ; 133 (5 suppl 2). 1709S - 1717S (Pubitemid 36548679)
56. Hobel CJ, Goldstein A, Barrett ES. Psychosocial stress and pregnancy outcome. Clin Obstet Gynecol. 2008 ; 51 (2). 333-348 (Pubitemid 351655105)
57. Mancuso RA, Schetter CD, Rini CM, Roesch SC, Hobel CJ. Maternal prenatal anxiety and corticotropin-releasing hormone associated with timing of delivery. Psychosom Med. 2004 ; 66 (5). 762-769 (Pubitemid 39332366)
58. Riley SC, Walton JC, Herlick JM, Challis JR. The localization and distribution of corticotropin-releasing hormone in the human placenta and fetal membranes throughout gestation. J Clin Endocrinol Metab. 1991 ; 72 (5). 1001-1007 (Pubitemid 21921798)
59. Power ML, Schulkin J. Functions of corticotropin-releasing hormone in anthropoid primates: from brain to placenta. Am J Hum Biol. 2006 ; 18 (4). 431-447 (Pubitemid 44083522)
60. Schulkin J. Corticotropin-releasing hormone signals adversity in both the placenta and the brain: regulation by glucocorticoids and allostatic overload. J Endocrinol. 1999 ; 161 (3). 349-356 (Pubitemid 29278790)
61. Hobel CJ, Arora CP, Korst LM. Corticotrophin-releasing hormone and CRH-binding protein. Differences between patients at risk for preterm birth and hypertension. Ann N Y Acad Sci. 1999 ; 897 ((1). 54-65 (Pubitemid 30040319)
62. McLean M, Bisits A, Davies J, et al. Predicting risk of preterm delivery by second-trimester measurement of maternal plasma corticotropin-releasing hormone and alpha-fetoprotein concentrations. Am J Obstet Gynecol. 1999 ; 181 (1). 207-215 (Pubitemid 29343357)
63. Hendler I, Goldenberg RL, Mercer BM, et al. The preterm prediction study: association between maternal body mass index and spontaneous and indicated preterm birth. Am J Obstet Gynecol. 2005 ; 192 (3). 882-886 (Pubitemid 40311284)
64. McDonald SD, Han Z, Mulla S, Beyene J. Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and meta-analyses. BMJ. 2010 ; 341: c3428
65. Torloni MR, Betran AP, Daher S, et al. Maternal BMI and preterm birth: a systematic review of the literature with meta-analysis. J Matern Fetal Neonatal Med. 2009 ; 22 (11). 957-970
66. Zhu XO, Yang Z, Guo CM, et al. Paradoxical stimulation of cyclooxygenase-2 expression by glucocorticoids via a cyclic AMP response element in human amnion fibroblasts. Mol Endocrinol. 2009 ; 23 (11). 1839-1849
67. Clifton VL. Review: sex and the human placenta: mediating differential strategies of fetal growth and survival. Placenta. 2010 ; 31 (suppl). S33 - S39
68. Yeganegi M, Leung CG, Martins A, et al. Lactobacillus rhamnosus GR-1 stimulates colony-stimulating factor 3 (granulocyte) (CSF3) output in placental trophoblast cells in a fetal sex-dependent manner. Biol Reprod. 2011 ; 84 (1). 18-25
69. Cooperstock M, Campbell J. Excess males in preterm birth: interactions with gestational age, race, and multiple birth. Obstet Gynecol. 1996 ; 88 (2). 189-193 (Pubitemid 26250289)
70. Pennell CE, Jacobsson B, Williams SM, et al. Genetic epidemiologic studies of preterm birth: guidelines for research. Am J Obstet Gynecol. 2007 ; 196 (2). 107-118 (Pubitemid 46239999)
71. Girotti M, Zingg HH. Gene expression profiling of rat uterus at different stages of parturition. Endocrinology. 2003 ; 144 (6). 2254-2265 (Pubitemid 36629875)
72. Song J, Zhang X, Qi Z, et al. Cloning and characterization of a calcium-activated chloride channel in rat uterus. Biol Reprod. 2009 ; 80 (4). 788-794
73. Mittal P, Romero R, Tarca AL, et al. Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term. J Perinat Med. 2010 ; 38 (6). 617-643
74. Tattersall M, Engineer N, Khanjani S, et al. Pro-labour myometrial gene expression: are preterm labour and term labour the same?. Reproduction. 2008 ; 135 (4). 569-579 (Pubitemid 351578163)
75. Gibb W, Challis JR. Mechanisms of term and preterm birth. J Obstet Gynaecol Can. 2002 ; 24 (11). 874-883
76. Myatt L, Lye SJ. Expression, localization and function of prostaglandin receptors in myometrium. Prostaglandins Leukot Essent Fatty Acids. 2004 ; 70 (2). 137-148 (Pubitemid 38141902)