Evaluating the effects of ginger extract on knee pain, stiffness and difficulty in patients with knee osteoarthritis

Journal of Medicinal Plants Research

Volumn 5, Issue 15, 2011, Pages 3375-3379

  Zakeri, Zahra ^a   Izadi, Shahrokh ^a   Bari, Zohreh ^a   Soltani, Farhang ^a   Narouie, Behzad ^a   Ghasemi Rad, Mohammad ^b  

^a ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Ginger; Human; Knee; Osteoarthritis; Pain; Randomized clinical trial; Stiffness

Indexed keywords

GINGER EXTRACT; PARACETAMOL; PLACEBO;

ADULT; AGED; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DYSPEPSIA; FEMALE; HEARTBURN; HUMAN; JOINT STIFFNESS; KNEE OSTEOARTHRITIS; KNEE PAIN; MAJOR CLINICAL STUDY; MALE; MORNING STIFFNESS; OUTCOME ASSESSMENT; PAIN ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; VISUAL ANALOG SCALE;

ZINGIBER OFFICINALE;

EID: 84860401956     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Ali BH, Blunden G, Tanira MO, Nemmar A (2008). Some phytochemical and toxilogical properties of ginger (zingiber officinale roscoe): A review of recent research. Food Chem Toxicol., 46(2): 409-429.
2. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Borenstein K (1986). Development of criteria for the classification and reporting of osteoarthritis: Classification of the osteoarthritis of the knee. Arthritis Rheum., 29: 1039-1049.
3. Altman RD, Marcussen KC (2001). Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum., 44(11): 2531-2538.
4. Awang D (1992). Ginger. Can Pharm J., pp. 309-311.
5. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J (1988). Validation study of womac: A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J. Rheumatol., 15: 1833-1840.
6. Bliddal H, Rosetzsky A, Schlichting P, Weidner MS, Anderson LA, Ibfelt H (2000). A randomized, placebo - controlled, cross - over study of ginger extract and ibuprofen in osteoarthritis. Osteoarthritis cartilage, 8: 9-12.
7. Chrubasik JE, Roufogalis BD, Chrubasik S (2007). Evidence of effectiveness of herbal anti-inflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain. Phytother. Res., 21(7): 675-683.
8. Felson DT (2006). Clinical practice. Osteoarthritis of the knee. N. Engl. J. Med., 354(8):841-848. Available from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16495396. DOI 354/8/841 [pii]10.1056/NEJMcp051726.
9. Frondoza CG, Sohrabi A (2004). An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human synoviocyte cultures. In vitro Cell Dev. Biol. Anim., 40: 95-101.
10. Grznna R, Lindmark L, Frondoza CG (2005). Ginger- an herbal medical product with broad anti-inflammatory actions. J. Med. Food, 8(2): 125-132.
11. Hochberg MC, Altman RD, Brandt KD, Clark BM, Dieppe PA, Griffin MR (1995). Guidelines for the medical management of osteoarthritis: Part II. Osteoarthritis of the knee. Arthritis Rheum., 38: 1541-1546.
12. Laurent G, Ameye LG, Winniessehee WS (2006). Osteoarthritis and nutrition. Arthritis Res. Ther., 8: 1-22.
13. Long L, Soeken K, Ernst E (2001). Herbal medicines for the treatment of osteoarthritis. Rheumatology, 40: 779-793.
14. Lozada CJ, Altman RD (2001). Management of osteoarthritis. In. 14 Edn., Baltimore Lippincott, Williams and Wilkins.
15. Murray CJL, Lopez AD (1997). The global burden of disease geneva. world Health organization.
16. Nisha JM (2001). Medical management of osteoarthritis. Mayoclin. Proc., 76: 533-539.
17. Pendleton A, Arden N, Dougados M, Doherty M, Bannwarth B, Bijlsma JMJ (2000). Eular recommendations for therapy of knee osteoarthritis: Report of a task force of standing committee for international clinical studies including therapeutic trials (escisito). Ann. Rheum. Dis., 59: 936-944.
18. Srivastava KC, Mustafa T (1992). Ginger (Zingiber official) in rheumatism and musculoskeletal disorders. Med. Hypotheses, 39(4): 342-348.
19. Trease GE, Evans WC (1983). Pharmacognosy. 12nd Edn., London: Bailliere Tindall.
20. Wewers ME, Lowe NK (1990). A critical review of visual analog scale n the measurement of clinical phenomena. Res. Nurs. Health, 13: 227-236.
21. Wigler I, Grotto, Caspi D, YM (2003). The effects of zintoma ec (a ginger extract) on symptomatic osteoarthritis osteoarthritis Cartilage, 11: 783-789.
22. Wolfe F (1999). Determinants of womac function, pain and stiffness scores: Evidence for the role of low back pain, symptom counts, fatigue and depression in osteoarthritis, rheumatoid arthritis and fibromyalgia. Rheumatology, 38: 355-361.