Photobleaching-based method to individualize irradiation time during interstitial 5-aminolevulinic acid photodynamic therapy

Photodiagnosis and Photodynamic Therapy

Volumn 8, Issue 3, 2011, Pages 275-281

  Hennig, Georg ^a   Stepp, Herbert ^a   Johansson, Ann ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

42.62.Be (biological and medical applications); 87.10.Kn (finite element calculations); 87.50.wj (dosimetry exposure assessment); 87.50.wp (therapeutic applications); 87.64.Cc (scattering of visible, uv, and infrared radiation); 87.64.kv (fluorescence); Brain PDT; Dosimetry; Finite element method; Fluorescence; Interstitial photodynamic therapy

Indexed keywords

AMINOLEVULINIC ACID; BLEACHING AGENT; PHOTOSENSITIZING AGENT;

ARTICLE; BLEACHING; COMPUTER SIMULATION; CONTROLLED STUDY; FLUORESCENCE; HUMAN; IRRADIATION; MONITORING; OPTICS; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

ABSORPTION; ALGORITHMS; AMINOLEVULINIC ACID; BRAIN NEOPLASMS; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; FLUORESCENCE; GLIOBLASTOMA; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PHOTOBLEACHING; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS; RADIATION DOSAGE; RADIOMETRY; SCATTERING, RADIATION; TIME FACTORS;

EID: 84860394828     PISSN: 15721000     EISSN: 18731597     Source Type: Journal    
DOI: 10.1016/j.pdpdt.2011.03.338     Document Type: Article

References (34)

1. Johansson A., Kreth F.W., Stummer W., Stepp H. Interstitial photodynamic therapy of brain tumors. IEEE J Sel Topics in Quantum Electron 2010, 16(4):841-853.
2. Beck T.J., Kreth F.W., Beyer W., et al. Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX. Lasers Surg Med 2007, 39(5):386-393.
3. Johansson A., Palte G., Schnell O., Herms J., Stepp H. 5-Aminolaevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumours. Photochem Photobiol 2010, 86(6):1373-1378.
4. Stummer W., Beck T., Beyer W., et al. Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report. J Neurooncol 2008, 87(1):103-109.
5. Castano A.P., Mroz P., Hamblin M.R. Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer 2006, 6(7):535-545.
6. Fingar V.H. Vascular effects of photodynamic therapy. J Clin Laser Med Surg 1996, 14(5):323-328.
7. Zhu T.C., Finlay J.C., Hahn S.M. Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy. J Photochem Photobiol B 2005, 79(3):231-241.
8. Wilson B.C., Patterson M.S., Lilge L. Implicit and explicit dosimetry in photodynamic therapy. Lasers Med Sci 1997, 12:182-199.
9. Weersink R.A., Bogaards A., Gertner M., et al. Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: clinical experience and practicalities. J Photochem Photobiol B 2005, 79(3):211-222.
10. Johansson A., Axelsson J., Andersson-Engels S., Swartling J. Realtime light dosimetry software tools for interstitial photodynamic therapy of the human prostate. Med Phys 2007, 34(11):4309-4321.
11. Finlay J.C., Mitra S., Patterson M.S., Foster T.H. Photobleaching kinetics of Photofrin in vivo and in multicell tumour spheroids indicate two simultaneous bleaching mechanisms. Phys Med Biol 2004, 49(21):4837-4860.
12. Wang K.K., Mitra S., Foster T.H. A comprehensive mathematical model of microscopic dose deposition in photodynamic therapy. Med Phys 2007, 34(1):282-293.
13. Wang K.K., Finlay J.C., Busch T.M., Hahn S.M., Zhu T.C. Explicit dosimetry for photodynamic therapy: macroscopic singlet oxygen modeling. J Biophotonics 2010, 3(5-6):304-318.
14. Jarvi M.T., Niedre M.J., Patterson M.S., Wilson B.C. Singlet oxygen luminescence dosimetry (SOLD) for photodynamic therapy: current status, challenges and future prospects. Photochem Photobiol 2006, 82(5):1198-1210.
15. Dysart J.S., Singh G., Patterson M.S. Calculation of singlet oxygen dose from photosensitizer fluorescence and photobleaching during mTHPC photodynamic therapy of MLL cells. Photochem Photobiol 2005, 81(1):196-205.
16. Robinson D.J., de Bruijn H.S., van der Veen N., Stringer M.R., Brown S.B., Star W.M. Protoporphyrin IX fluorescence photobleaching during ALA-mediated photodynamic therapy of UVB-induced tumors in hairless mouse skin. Photochem Photobiol 1999, 69(1):61-70.
17. Ericson M.B., Sandberg C., Stenquist B., et al. Photodynamic therapy of actinic keratosis at varying fluence rates: assessment of photobleaching, pain and primary clinical outcome. Br J Dermatol 2004, 151(6):1204-1212.
18. Cottrell W.J., Paquette A.D., Keymel K.R., Foster T.H., Oseroff A.R. Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. Clin Cancer Res 2008, 14(14):4475-4483.
19. Sheng C., Hoopes P.J., Hasan T., Pogue B.W. Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus. Photochem Photobiol 2007, 83(3):738-748.
20. Stepp H., Beck T., Pongratz T., et al. ALA and malignant glioma: fluorescence-guided resection and photodynamic treatment. J Environ Pathol Toxicol Oncol 2007, 26(2):157-164.
21. Lavi A., Weitman H., Holmes R.T., Smith K.M., Ehrenberg B. The depth of porphyrin in a membrane and the membrane's physical properties affect the photosensitizing efficiency. Biophys J 2002, 82(4):2101-2110.
22. Patterson M.S., Wilson B.C. A theoretical study of the influence of sensitizer photobleaching on depth of necrosis in photodynamic therapy. Proc SPIE 1994, 2133:208-219.
23. Beck T.J., Beyer W., Pongratz T., et al. Clinical determination of tissue optical properties in vivo by spatially resolved reflectance measurements. Proc SPIE 2003, 5138:96-105.
24. Vollet-Filho J.D., Menez P.F.C., Moriyama L.T., et al. Possibility for a full optical determination of photodynamic therapy outcome. J Appl Phys 2009, 105:102038.
25. Farrell T.J., Hawkes R.P., Patterson M.S., Wilson B.C. Modeling of photosensitizer fluorescence emission and photobleaching for photodynamic therapy dosimetry. Appl Opt 1998, 37(31):7168-7183.
26. Eleouet S., Rousset N., Carre J., et al. Heterogeneity of delta-aminolevulinic acid-induced protoporphyrin IX fluorescence in human glioma cells and leukemic lymphocytes. Neurol Res 2000, 22(4):361-368.
27. Madsen S.J., Angell-Petersen E., Spetalen S., Carper S.W., Ziegler S.A., Hirschberg H. Photodynamic therapy of newly implanted glioma cells in the rat brain. Lasers Surg Med 2006, 38(5):540-548.
28. Jacques S.L., Joseph R., Gofstein G. How photobleaching affects dosimetry and fluorescence monitoring of PDT in turbid media. Proc SPIE 1993, 1881:168-179.
29. Jongen A.J., Sterenborg H.J. Mathematical description of photobleaching in vivo describing the influence of tissue optics on measured fluorescence signals. Phys Med Biol 1997, 42(9):1701-1716.
30. Müller M.G., Georgakoudi I., Zhang Q., Wu J., Feld M.S. Intrinsic fluorescence spectroscopy in turbid media: disentangling effects of scattering and absorption. Appl Opt 2001, 40(25):4633-4646.
31. Jacques S.L. Light distributions from point, line and plane sources for photochemical reactions and fluorescence in turbid biological tissues. Photochem Photobiol 1998, 67(1):23-32.
32. Moan J., Streckyte G., Bagdonas S., Bech O., Berg K. Photobleaching of protoporphyrin IX in cells incubated with 5-aminolevulinic acid. Int J Cancer 1997, 70(1):90-97.
33. Forrer M., Glanzmann T., Mizeret J., et al. Fluorescence excitation and emission spectra of ALA induced protoporphyrin IX in normal and tumoral tissue of the human bladder. Optical biopsy and fluorescence spectroscopy and imaging 1994, 84-88. Proc. SPIE, Lille, France. R. Cubeddu, R. Marchesini, S.R. Mordon, K. Svanberg, H.H. Rinneberg, G. Wagnières (Eds.).
34. Wang K.K., Cottrell W.J., Mitra S., Oseroff A.R., Foster T.H. Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT. Lasers Surg Med 2009, 41(9):686-696.