Ultrasonic-assisted liquid-liquid extraction and HILIC-ELSD analysis of ginsenoside Rb1, astragaloside IV and dulcitol in sugar-free "Fufangfufangteng Heji"

Journal of Pharmaceutical and Biomedical Analysis

Volumn 56, Issue 4, 2011, Pages 836-840

  Qin, Jieping ^a   Feng, Jun ^a   Li, Yaohua ^a   Mo, Kefeng ^b   Lu, Shiying ^b  

^a GUANGXI UNIVERSITY OF CHINESE MEDICINE   (China)

^b Nanning Institute for Food and Drug Control   (China)

Author keywords

Astragaloside iv; Dulcitol; Ginsenoside rb1; Quantitative determination; Ultrasonic assisted extraction

Indexed keywords

ASTRAGALOSIDE IV; CHINESE DRUG; FUFANGFUFANGTENG HEJI; GALACTITOL; GINSENOSIDE RB 1; HERBACEOUS AGENT; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; ASTRAGALUS PLANT; CHINESE MEDICINE; DRUG DETERMINATION; EUONYMUS; GINSENG; LIQUID; LIQUID LIQUID EXTRACTION; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ULTRASOUND;

CALIBRATION; CARDIOTONIC AGENTS; CHROMATOGRAPHY, LIQUID; DRUG COMBINATIONS; GALACTITOL; GINSENOSIDES; LIGHT; LIQUID-LIQUID EXTRACTION; PLANT PREPARATIONS; REPRODUCIBILITY OF RESULTS; SAPONINS; SCATTERING, RADIATION; SOUND; TRITERPENES;

EID: 84860390198     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.07.033     Document Type: Article

References (16)

1. CHP. Part 1. Beijing: Chemical Industry Press; 2010. p. 910.
2. Huang H.Y. Study on the anti-aging effects of Fufangfufangteng Heji. Chin. Tradit. Pat. Med. 1994, 16:39-40.
3. Xie J.X., Lin Q.Y., Fang H., et al. Study on the effects of Fufangfufangteng Heji on cardiac vascular system. Guangxi J. Tradit. Chin. Med. 1993, 16:45-47.
4. Chen L. Clinical observations on the therapeutic effect of Fufangfufangteng Heji on anti-leukopenia after the chemotherapy. Guangxi J. Tradit. Chin. Med. 2001, 24:49-50.
5. Li L., Luo P.Z., Zhou L.X., et al. Antioxidation effect of Fufangteng and its mixture after cerebral ischemia-reperfusion injury in rats. Chin. J. Clin. Rehab. 2004, 28:6258-6259.
6. Li Z.P., Cao Q. Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats. Acta Pharm. Sini. 2002, 23:898-904.
7. Cheng Y., Shen L.H., Zhang J.T. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharm. Sini. 2005, 26:143-149.
8. Jiang Q.S., Huang X.N., Dai Z.K., et al. Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat. J. Ethnopharma. 2007, 111:567-572.
9. Qu F.L., Ding Q.L., Zhang H.M. Study on the chemical composition in Euonymus fortunei. J. Nanjing Mil. Med. Coll. 2003, 23:221-226.
10. Min S.G., Zhang S.Y., Xu X.Y., et al. Simultaneous determination of three Panax notoginseng saponins at sub-nanograms by LC-MS/MS in dog plasma for pharmacokinetics of compound Danshen tablets. J. Chromatogr. B 2010, 878:3331-3337.
11. Yan M.M., Liu W., Fu Y.J., et al. Optimization of the microwave-assisted extraction process for four main astragalosides in Radix Astragali. Food Chem. 2010, 119:1663-1670.
12. Qin J.P., Yao R., Li Y. Determination of dulcitol and astragaloside in Fufang Fufangteng capsules by HPLC-ELSD. Chin. Tradit. Pat. Med. 2008, 30:1468-1471.
13. Alperta A.J. Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. J. Chromatogr. A 1990, 499:177-196.
14. GÖoran K., Stefan W., Helena S. Separation of monosaccharides by hydrophilic interaction chromatography with evaporative light scattering detection. J. Chromatogr. A 2005, 1092:246-249.
15. Zhang S.Q., Zhang J.S., Wang C.Z. Extraction of steroid saponins from Paris polyphylla Sm. var. yunnanensis using novel ultrahigh pressure extraction technology. Pharm. Chem. J. 2007, 41:424-429.
16. Shin J.S., Ahn S.C., Choi S.W., et al. Ultra high pressure extraction (UHPE) of ginsenosides from Korean Panax ginseng powder. Food Sci. Biotechnol. 2010, 19:743-748.