The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi

FEBS Journal

Volumn 278, Issue 17, 2011, Pages 3164-3176

  Díaz Sánchez, Violeta ^a   Estrada, Alejandro F ^a   Trautmann, Danika ^b   Al Babili, Salim ^b   Avalos, Javier ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

apo 4 carotenal; apocarotenoids; carotenogenesis; carS mutants; light regulation

Indexed keywords

ALDEHYDE DEHYDROGENASE; CAROTENOID; MESSENGER RNA; NEUROSPORAXANTHIN; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; BIOSYNTHESIS; CARD GENE; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; FUNGAL GENE; FUSARIUM; FUSARIUM FUJIKUROI; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE TARGETING; GENETIC CODE; IN VITRO STUDY; IN VIVO STUDY; LIGHT EXPOSURE; MOLECULAR CLONING; NEUROSPORA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SPECIES COMPARISON; UPREGULATION; YLO 1 GENE;

ALDEHYDE DEHYDROGENASE; AMINO ACID SEQUENCE; CAROTENOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FUNGAL PROTEINS; FUSARIUM; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; LIGHT; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; NEUROSPORA CRASSA; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

ESCHERICHIA COLI; FUNGI; FUSARIUM; GIBBERELLA FUJIKUROI; NEUROSPORA; NEUROSPORA CRASSA;

EID: 84860390110     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08242.x     Document Type: Article

References (40)

1. Britton G, Liaaen-Jensen S, &, Pfander H, (1998) Carotenoids. Birkhäuser Verlag, Basel.
2. Cuttriss AJ, &, Pogson BJ, (2006) Carotenoids. In The Structure and Function of Plastids (, Wise RR, &, Hoober JK, eds), pp. 315-334. Springer, Dordrecht, The Netherlands.
3. von Lintig J, (2010) Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism. Annu Rev Nutr 30, 35-56.
4. Sandmann G, &, Misawa N, (2002) Fungal carotenoids. In The Mycota X Industrial Applications (, Osiewacz HD, ed.), pp. 247-262. Springer Verlag, Berlin Heidelberg.
5. Avalos J, &, Cerdá-Olmedo E, (2004) Fungal carotenoid production. In Handbook of Fungal Biotechnology (, Arora DK, ed.), pp. 367-378. Marcel Dekker, New York.
6. Avalos J, Cerdá-Olmedo E, Reyes F, &, Barrero AF, (2007) Gibberellins and other metabolites of Fusarium fujikuroi and related fungi. Curr Org Chem 11, 721-737. (Pubitemid 46746340)
7. Zalokar M, (1957) Isolation of an acidic pigment in Neurospora. Arch Biochem Biophys 70, 568-571.
8. Linnemannstöns P, Prado MM, Fernandez-Martin R, Tudzynski B, &, Avalos J, (2002) A carotenoid biosynthesis gene cluster in Fusarium fujikuroi: the genes carB and carRA. Mol Genet Genomics 267, 593-602. (Pubitemid 34824188)
9. Fernández-Martín R, Cerdá-Olmedo E, &, Avalos J, (2000) Homologous recombination and allele replacement in transformants of Fusarium fujikuroi. Mol Gen Genet 263, 838-845.
10. Prado-Cabrero A, Schaub P, Díaz-Sánchez V, Estrada AF, Al-Babili S, &, Avalos J, (2009) Deviation of the neurosporaxanthin pathway towards β-carotene biosynthesis in Fusarium fujikuroi by a point mutation in the phytoene desaturase gene. FEBS J 276, 4582-4597.
11. Prado-Cabrero A, Estrada AF, Al-Babili S, &, Avalos J, (2007) Identification and biochemical characterization of a novel carotenoid oxygenase: elucidation of the cleavage step in the Fusarium carotenoid pathway. Mol Microbiol 64, 448-460. (Pubitemid 46632625)
12. Prado-Cabrero A, Scherzinger D, Avalos J, &, Al-Babili S, (2007) Retinal biosynthesis in fungi: characterization of the carotenoid oxygenase CarX from Fusarium fujikuroi. Eukaryot Cell 6, 650-657. (Pubitemid 46697545)
13. Prado MM, Prado-Cabrero A, Fernández-Martín R, &, Avalos J, (2004) A gene of the opsin family in the carotenoid gene cluster of Fusarium fujikuroi. Curr Genet 46, 47-58. (Pubitemid 39089038)
14. Estrada AF, &, Avalos J, (2009) Regulation and targeted mutation of opsA, coding for the NOP-1 opsin orthologue in Fusarium fujikuroi. J Mol Biol 387, 59-73.
15. Avalos J, &, Cerdá-Olmedo E, (1987) Carotenoid mutants of Gibberella fujikuroi. Curr Genet 25, 1837-1841.
16. Avalos J, &, Schrott EL, (1990) Photoinduction of carotenoid biosynthesis in Gibberella fujikuroi. FEMS Microbiol Lett 66, 295-298. (Pubitemid 20014257)
17. Rodríguez-Ortiz R, Limón MC, &, Avalos J, (2009) Regulation of carotenogenesis and secondary metabolism by nitrogen in wild-type Fusarium fujikuroi and carotenoid-overproducing mutants. Appl Environ Microbiol 75, 405-413.
18. Thewes S, Prado-Cabrero A, Prado MM, Tudzynski B, &, Avalos J, (2005) Characterization of a gene in the car cluster of Fusarium fujikuroi that codes for a protein of the carotenoid oxygenase family. Mol Genet Genomics 274, 217-228. (Pubitemid 41478840)
19. Avalos J, &, Estrada AF, (2010) Regulation by light in Fusarium. Fungal Genet Biol 47, 930-938.
20. Schmidhauser TJ, Lauter FR, Russo VE, &, Yanofsky C, (1990) Cloning, sequence, and photoregulation of al-1, a carotenoid biosynthetic gene of Neurospora crassa. Mol Cell Biol 10, 5064-5070.
21. Schmidhauser TJ, Lauter FR, Schumacher M, Zhou W, Russo VE, &, Yanofsky C, (1994) Characterization of al-2, the phytoene synthase gene of Neurospora crassa. Cloning, sequence analysis, and photoregulation. J Biol Chem 269, 12060-12066.
22. Arrach N, Schmidhauser TJ, &, Avalos J, (2002) Mutants of the carotene cyclase domain of al-2 from Neurospora crassa. Mol Genet Genomics 266, 914-921.
23. Saelices L, Youssar L, Holdermann I, Al-Babili S, &, Avalos J, (2007) Identification of the gene responsible for torulene cleavage in the Neurospora carotenoid pathway. Mol Genet Genomics 278, 527-537. (Pubitemid 47568704)
24. Estrada AF, Youssar L, Scherzinger D, Al-Babili S, &, Avalos J, (2008) The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway. Mol Microbiol 69, 1207-1220.
25. Estrada AF, Maier D, Scherzinger D, Avalos J, &, Al-Babili S, (2008) Novel apocarotenoid intermediates in Neurospora crassa mutants imply a new biosynthetic reaction sequence leading to neurosporaxanthin formation. Fungal Genet Biol 45, 1497-1505.
26. Jin JM, Lee J, &, Lee YW, (2010) Characterization of carotenoid biosynthetic genes in the ascomycete Gibberella zeae. FEMS Microbiol Lett 302, 197-202.
27. Beutner S, Bloedorn B, Frixel S, Hernández Blanco I, Hoffmann T, Martin H-D, Mayer B, Noack P, Ruck C, Schmidt M, et al. (2001) Quantitative assessment of antioxidant properties of natural colorants and phytochemicals: carotenoids, flavonoids, phenols and indigoids. The role of β-carotene in antioxidant functions. J Sci Food Agric 81, 559-568. (Pubitemid 32386131)
28. Avalos J, &, Cerdá-Olmedo E, (1986) Chemical modification of carotenogenesis in Gibberella fujikuroi. Phytochemistry 25, 1837-1841.
29. Avalos J, Mackenzie A, Nelki DS, &, Bramley PM, (1988) Terpenoid biosynthesis in cell-extracts of wild type and mutant strains of Gibberella fujikuroi. Biochim Biophys Acta 966, 257-265.
30. Valadon LRG, &, Mummery RS, (1977) Natural β-apo-4′- carotenoic acid methyl ester in the fungus Verticillium agaricinum. Phytochemistry 16, 613-614.
31. Sakaki H, Kaneno H, Sumiya Y, Tsushima M, Miki W, Kishimoto N, Fujita T, Matsumoto S, Komemushi S, &, Sawabe A, (2002) A new carotenoid glycosyl ester isolated from a marine microorganism, Fusarium strain T-1. J Nat Prod 65, 1683-1684. (Pubitemid 35386806)
32. Valadon LRG, Osman M, Mummery RS, Jerebzoff-Quintin S, &, Jerebzoff S, (1982) The effect of monochromatic radiation in the range 350 to 750 nm on the carotenogenesis in Verticillium agaricinum. Physiol Plant 56, 199-203.
33. Leslie J, (1991) Mating populations in Gibberella fujikuroi (Fusarium section Liseola). Phytopathology 81, 1058-1060.
34. O'Donnell K, Cigelnik E, &, Niremberg HI, (1998) Molecular systematics and phylogeography of the Gibberella fujikuroi species complex. Mycologia 90, 465-493. (Pubitemid 28273436)
35. Avalos J, Casadesús J, &, Cerdá-Olmedo E, (1985) Gibberella fujikuroi mutants obtained with UV radiation and N-methyl-N′- nitro-N-nitrosoguanidine. Appl Environ Microbiol 49, 187-191. (Pubitemid 15184422)
36. Punt PJ, Oliver RP, Dingemanse MA, Pouwels PH, &, van den Hondel CA, (1987) Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli. Gene 56, 117-124.
37. Proctor RH, Hohn TM, &, McCormick SP, (1997) Restoration of wild-type virulence to Tri5 disruption mutants of Gibberella zeae via gene reversion and mutant complementation. Microbiology 143, 2583-2591. (Pubitemid 27389944)
38. Sambrook J, &, Russell DW, (2001) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
39. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, &, Higgins DG, (1997) The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 24, 4876-4882. (Pubitemid 28022245)
40. Schultz J, Milpetz F, Bork P, &, Ponting CP, (1998) SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci USA 95, 5857-5864. (Pubitemid 28248931)