The determinants that Govern microtubule assembly from the atomic structure of GTP-tubulin

Journal of Molecular Biology

Volumn 412, Issue 1, 2011, Pages 35-42

  Nawrotek, Agata ^a   Knossow, Marcel ^a   Gigant, Benoît ^a  

^a LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

Author keywords

cytoskeleton; microtubule dynamics; nucleotide; tubulin structural cycle; X ray crystallography

Indexed keywords

ALPHA TUBULIN; BETA TUBULIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; STATHMIN; TUBULIN;

ARTICLE; ATOM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; MICROTUBULE ASSEMBLY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

EID: 84860390007     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.07.029     Document Type: Article

References (32)

1. Nogales E., Whittaker M., Milligan R.A., and Downing K.H. High-resolution model of the microtubule Cell 96 1999 79 88 (Pubitemid 29044155)
2. Sui H., and Downing K.H. Structural basis of interprotofilament interaction and lateral deformation of microtubules Structure 18 2010 1022 1031
3. Desai A., and Mitchison T.J. Microtubule polymerization dynamics Annu. Rev. Cell Dev. Biol. 13 1997 83 117 (Pubitemid 28034521)
4. Müller-Reichert T., Chrétien D., Severin F., and Hyman A.A. Structural changes at microtubule ends accompanying GTP hydrolysis: information from a slowly hydrolyzable analogue of GTP, guanylyl (α,β) methylenediphosphonate Proc. Natl Acad. Sci. USA 95 1998 3661 3666 (Pubitemid 28173184)
5. Buey R.M., Diaz J.F., and Andreu J.M. The nucleotide switch of tubulin and microtubule assembly: a polymerization-driven structural change Biochemistry 45 2006 5933 5938 (Pubitemid 43727084)
6. Gigant B., Curmi P.A., Martin-Barbey C., Charbaut E., Lachkar S., and Lebeau L. The 4 Å X-ray structure of a tubulin:stathmin-like domain complex Cell 102 2000 809 816
7. Nogales E., Downing K.H., Amos L.A., and Lowe J. Tubulin and FtsZ form a distinct family of GTPases Nat. Struct. Biol. 5 1998 451 458 (Pubitemid 28265028)
8. Dorléans A., Gigant B., Ravelli R.B., Mailliet P., Mikol V., and Knossow M. Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc. Natl Acad. Sci. USA 106 2009 13775 13779
9. Ravelli R.B., Gigant B., Curmi P.A., Jourdain I., Lachkar S., Sobel A., and Knossow M. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain Nature 428 2004 198 202 (Pubitemid 38374318)
10. Rice L.M., Montabana E.A., and Agard D.A. The lattice as allosteric effector: structural studies of αβ- and γ-tubulin clarify the role of GTP in microtubule assembly Proc. Natl Acad. Sci. USA 105 2008 5378 5383 (Pubitemid 351753871)
11. Wang H.W., and Nogales E. Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly Nature 435 2005 911 915 (Pubitemid 40896310)
12. Barbier P., Dorleans A., Devred F., Sanz L., Allegro D., and Alfonso C. Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers J. Biol. Chem. 285 2010 31672 31681
13. Grafmüller A., and Voth G.A. Intrinsic bending of microtubule protofilaments Structure 19 2011 409 417
14. Knipling L., Hwang J., and Wolff J. Preparation and properties of pure tubulin S Cell Motil. Cytoskeleton 43 1999 63 71 (Pubitemid 29236876)
15. Banerjee A., Roach M.C., Wall K.A., Lopata M.A., Cleveland D.W., and Luduena R.F. A monoclonal antibody against the type II isotype of β-tubulin. Preparation of isotypically altered tubulin J. Biol. Chem. 263 1988 3029 3034 (Pubitemid 18062960)
16. Lowe J., Li H., Downing K.H., and Nogales E. Refined structure of αβ-tubulin at 3.5 Å resolution J. Mol. Biol. 313 2001 1045 1057 (Pubitemid 33081900)
17. Valiron O., Arnal I., Caudron N., and Job D. GDP-tubulin incorporation into growing microtubules modulates polymer stability J. Biol. Chem. 285 2010 17507 17513
18. Honnappa S., Cutting B., Jahnke W., Seelig J., and Steinmetz M.O. Thermodynamics of the Op18/stathmin-tubulin interaction J. Biol. Chem. 278 2003 38926 38934 (Pubitemid 37221793)
19. Cormier A., Marchand M., Ravelli R.B., Knossow M., and Gigant B. Structural insight into the inhibition of tubulin by vinca domain peptide ligands EMBO Rep. 9 2008 1101 1106
20. Gigant B., Wang C., Ravelli R.B., Roussi F., Steinmetz M.O., and Curmi P.A. Structural basis for the regulation of tubulin by vinblastine Nature 435 2005 519 522 (Pubitemid 40734250)
21. Chretien D., Fuller S.D., and Karsenti E. Structure of growing microtubule ends: two-dimensional sheets close into tubes at variable rates J. Cell Biol. 129 1995 1311 1328
22. Castoldi M., and Popov A.V. Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer Protein Expression Purif. 32 2003 83 88 (Pubitemid 37436140)
23. 2+ dependence of guanine nucleotide binding to tubulin J. Biol. Chem. 262 1987 17278 17284 (Pubitemid 18032199)
24. Charbaut E., Curmi P.A., Ozon S., Lachkar S., Redeker V., and Sobel A. Stathmin family proteins display specific molecular and tubulin binding properties J. Biol. Chem. 276 2001 16146 16154
25. Dorléans A., Knossow M., and Gigant B. Studying drug-tubulin interactions by X-ray crystallography Methods Mol. Med. 137 2007 235 243
26. Wang C., Cormier A., Gigant B., and Knossow M. Insight into the GTPase activity of tubulin from complexes with stathmin-like domains Biochemistry 46 2007 10595 10602 (Pubitemid 47417253)
27. Caplow M., Ruhlen R.L., and Shanks J. The free energy for hydrolysis of a microtubule-bound nucleotide triphosphate is near zero: all of the free energy for hydrolysis is stored in the microtubule lattice J. Cell Biol. 127 1994 779 788 (Pubitemid 24332972)
28. Kabsch W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants J. Appl. Crystallogr. 26 1993 795 800
29. Navaza J. Implementation of molecular replacement in AMoRe Acta Crystallogr., Sect. D: Biol. Crystallogr. 57 2001 1367 1372 (Pubitemid 36117184)
30. Bricogne G., Blanc E., Brandl M., Flensburg C., Keller P., and Paciorek W. BUSTER 2.8.0 Edit 2009 Global Phasing Ltd. Cambridge, UK
31. Emsley P., and Cowtan K. Coot: model-building tools for molecular graphics Acta Crystallogr., Sect. D: Biol. Crystallogr. 60 2004 2126 2132 (Pubitemid 41742764)
32. DeLano W.L. The PyMOL Molecular Graphics System 2002 DeLano Scientific Schrödinger, LLC