Experimental and husbandry procedures as potential modifiers of the results of phenotyping tests

Physiology and Behavior

Volumn 106, Issue 5, 2012, Pages 602-611

  Gerdin, Anna Karin ^a   Igosheva, Natalia ^a   Roberson, Laura Anne ^a   Ismail, Ozama ^a   Karp, Natasha ^a   Sanderson, Mark ^a   Cambridge, Emma ^a   Shannon, Carl ^a   Sunter, David ^a   Ramirez Solis, Ramiro ^a   Bussell, James ^a   White, Jacqueline K ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Blood glucose; Core temperature; Husbandry; Radiotelemetry; Stress response; Systematic large scale phenotyping

Indexed keywords

GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL HUSBANDRY; ARTERIAL PRESSURE; ARTICLE; BODY WEIGHT; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORE TEMPERATURE; EXPERIMENTATION; FEMALE; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HEART RATE; LOCOMOTION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STRESS; TELEMETRY; VALIDITY;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BLOOD GLUCOSE; BLOOD PRESSURE; BODY TEMPERATURE; DISEASE MODELS, ANIMAL; FASTING; FEMALE; HEART RATE; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PHENOTYPE; SEX FACTORS; STRESS, PSYCHOLOGICAL; TELEMETRY; TIME FACTORS;

EID: 84860380368     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2012.03.026     Document Type: Article

References (44)

1. Austin C., Battey J., Bradley A., Bucan M., Capecchi M., Collins F., et al. The knockout mouse project. Nat Genet 2004, 36:921-924.
2. Skarnes W.C., Rosen B., West A.P., Koutsourakis M, Bushell W, Iyer V, et al. A conditional knockout resource for the genome-wide study of mouse gene function. Nature 2011, 474:337-342.
3. Brown S.D.M., Wurst W., Kühn R., Hancock J.M. The functional annotation of mammalian genomes: the challenge of phenotyping. Annu Rev Genet 2009, 43:305-333.
4. Testa G., Schaft J., van der Hoeven F., Glaser S., Anastassiadis K., Zhang Y., et al. A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles. Genesis 2004, 38:151-158.
5. Gates H., Mallon A.M., Brown S.D. High-throughput mouse phenotyping. Methods 2011, 53:394-404.
6. Mandillo S., Tucci V., Holter S.M., Meziane H., Banchaabouchi M.A., Kallnik M., et al. Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiol Genomics 2008, 34:243-255.
7. Crabbe J.C., Wahlsten D., Dudek B.C. Genetics of mouse behavior: interactions with laboratory environment. Science 1999, 284:1670-1672.
8. Champy M., Selloum M., Zeitler V., Caradec C., Jung B., Rousseau S., et al. Genetic background determines metabolic phenotypes in the mouse. Mamm Genome 2008, 19:318-331.
9. Morice E., Denis C., Giros B., Nosten-Bertrand M. Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background. Eur J Neurosci 2004, 20:120-126.
10. Champy M.F., Selloum M., Piard L., Zeitler V., Caradec C., Chambon P., et al. Mouse functional genomics requires standardization of mouse handling and housing conditions. Mamm Genome 2004, 15:768-783.
11. De Maio A., Torres M., Reeves R. Genetic determinants influencing the response to injury, inflammation, and sepsis. Shock 2005, 23:11-17.
12. Wurbel H. Ideal homes? Housing effects on rodent brain and behaviour. Trends Neurosci 2001, 24:207-211.
13. Nithianantharajah J., Barkus C., Murphy M., Hannan A. Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice. Neurobiol Dis 2008, 29:490-504.
14. Richter S., Garner J., Wurbel H. Environmental standardization: cure or cause of poor reproducibility in animal experiments?. Nat Methods 2009, 6:257-261.
15. Balcombe J., Barnard N., Sandusky C. Laboratory Routines Cause Animal Stress. Contemp Top Lab Anim Sci 2004, 43:42-51.
16. Castelhano-Carlos M.J., Baumans V. The impact of light, noise, cage cleaning and in-house transport on welfare and stress of laboratory rats. Lab Anim 2009, 43:311-327.
17. Duke J., Zammit T., Lawson D. The effects of routine cage-changing on cardiovascular and behavioral parameters in male Sprague-Dawley rats. Contemp Top Lab Anim Sci 2001, 40:17-20.
18. Tabata H., Kitamura T., Nagamatsu N. Comparison of effects of restraint, cage transportation, anaesthesia and repeated bleeding on plasma glucose levels between mice and rats. Lab Anim 1998, 32:143-148.
19. Leon L.R., Walker L.D., DuBose D.A., Stephenson L.A. Biotelemetry transmitter implantation in rodents: impact on growth and circadian rhythms. Am J Physiol Regul Integr Comp Physiol 2004, 286:R967-R974.
20. Hawkins P., Morton D.B., Bevan R., Heath K., Kirkwood J., Pearce P., et al. Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part B. Lab Anim 2004, 38:1-10.
21. Zethof T.J., Van der Heyden J.A., Tolboom J.T., Olivier B. Stress-induced hyperthermia as a putative anxiety model. Eur J Pharmacol 1995, 294:125-135.
22. Thurston J.H., Hauhart R.E. Effect of momentary stress on brain energy metabolism in weanling mice: apparent use of lactate as cerebral metabolic fuel concomitant with a decrease in brain glucose utilization. Metab Brain Dis 1989, 4:177-186.
23. Meijer M.K., Spruijt B.M., van Zutphen L.F.M., Baumans V. Effect of restraint and injection methods on heart rate and body temperature in mice. Lab Anim 2006, 40:382-391.
24. Tuli J., Smith J., Morton D. Stress measurements in mice after transportation. Lab Anim 1995, 29:132-138.
25. Yamada K., Ohki-Hamazaki H., Wada K. Differential effects of social isolation upon body weight, food consumption, and responsiveness to novel and social environment in bombesin receptor subtype-3 (BRS-3) deficient mice. Physiol Behav 2000, 68:555-561.
26. Meijer M.K., Sommer R., Spruijt B.M., van Zutphen L.F., Baumans V. Influence of environmental enrichment and handling on the acute stress response in individually housed mice. Lab Anim 2007, 41:161-173.
27. Baldwin D.R., Wilcox Z.C., Baylosis R.C. Impact of differential housing on humoral immunity following exposure to an acute stressor in rats. Physiol Behav 1995, 57:649-653.
28. Herd J.A. Cardiovascular response to stress. Physiol Rev 1991, 71:305-330.
29. Amico J.A., Cai H.M., Vollmer R.R. Corticosterone release in oxytocin gene deletion mice following exposure to psychogenic versus non-psychogenic stress. Neurosci Lett 2008, 442:262-266.
30. Andrikopoulos S., Blair A.R., Deluca N., Fam B.C., Proietto J. Evaluating the glucose tolerance test in mice. Am J Physiol Endocrinol Metab 2008, 295:E1323-E1332.
31. Ayala J.E., Samuel V.T., Morton G.J., Obici S., Croniger C.M., Shulman G.I., et al. Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice. Dis Model Mech 2010, 3:525-534.
32. Swoap S.J., Gutilla M.J. Cardiovascular changes during daily torpor in the laboratory mouse. Am J Physiol Regul Integr Comp Physiol 2009, 297:R769-R774.
33. Kramer K., van Acker S.A., Voss H.P., Grimbergen J.A., van der Vijgh W.J., Bast A. Use of telemetry to record electrocardiogram and heart rate in freely moving mice. J Pharmacol Toxicol Methods 1993, 30:209-215.
34. Hoppe C., Moritz K., Fitzgerald S., Bertram J., Evans R. Transient hypertension and sustained tachycardia in mice housed individually in metabolism cages. Physiol Res 2009, 58:69-75.
35. Sharp J., Zammit T., Lawson D. Stress-like responses to common procedures in rats: effect of the estrous cycle. Contemp Top Lab Anim Sci 2002, 41:15-22.
36. Sharp J., Zammit T., Azar T., Lawson D. Stress-like responses to common procedures in male rats housed alone or with other rats. Contemp Top Lab Anim Sci 2002, 41:8-14.
37. Du X.J., Fang L., Kiriazis H. Sex dimorphism in cardiac pathophysiology: experimental findings, hormonal mechanisms, and molecular mechanisms. Pharmacol Ther 2006, 111:434-475.
38. Bartolomucci A. Individual housing induces altered immuno-endocrine responses to psychological stress in male mice. Psychoneuroendocrinology 2003, 28:540-558.
39. Van Loo P.L.P., Van de Weerd H.A., Van Zutphen L.F.M., Baumans V. Preference for social contact versus environmental enrichment in male laboratory mice. Lab Anim 2004, 38:178-188.
40. Pham T.M., Hagman B., Codita A., Van Loo P.L.P., Strömmer L., Baumans V. Housing environment influences the need for pain relief during post-operative recovery in mice. Physiol Behav 2010, 99:663-668.
41. Van Loo P.L.P., Kuin N., Sommer R., Avsaroglu H., Pham T., Baumans V. Impact of 'living apart together' on postoperative recovery of mice compared with social and individual housing. Lab Anim 2007, 41:441-455.
42. Burn C.C., Peters A., Day M.J., Mason G.J. Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare, and handleability: a cross-laboratory study. Lab Anim 2006, 40:353-370.
43. Rosenbaum M., VandeWoude S., Johnson T. Effects of cage change frequency and bedding volume on mice and their microenvironment. JAALAS 2009, 48:763-773.
44. Reeb-Whitaker C.K., Paigen B., Beamer W.G., Bronson R.T., Churchill G.A., Schweitzer I.B., et al. The impact of reduced frequency of cage changes on the health of mice housed in ventilated cages. Lab Anim 2001, 35:58-73.