Working memory in the aged Ts65Dn mouse, a model for Down syndrome

Behavioural Brain Research

Volumn 232, Issue 1, 2012, Pages 202-209

  Whitney, Katharine N ^a   Wenger, Galen R ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Down syndrome; Lifespan; Matching to position; Memory; Ts65Dn

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; LIFESPAN; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; REINFORCEMENT; TASK PERFORMANCE; WORKING MEMORY;

AGING; ANIMALS; ANTIDEPRESSIVE AGENTS; CENTRAL NERVOUS SYSTEM STIMULANTS; COGNITION; CONDITIONING, OPERANT; DEXTROAMPHETAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN SYNDROME; INDANS; LONGITUDINAL STUDIES; MALE; MEMANTINE; MEMORY, SHORT-TERM; MICE; MICE, NEUROLOGIC MUTANTS; NOOTROPIC AGENTS; PIPERIDINES; PSYCHOMOTOR PERFORMANCE; ROLIPRAM;

EID: 84860341441     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.03.042     Document Type: Article

References (43)

1. Akeson E.C., Lambert J.P., Narayanswami S., Gardiner K., Bechtel L.J., Davisson M.T. Ts65Dn - localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome. Cytogenetics and Cell Genetics 2001, 93:270-276.
2. Antonarakis S.E., Epstein C.J. The challenge of Down syndrome. Trends in Molecular Medicine 2006, 12:473-479.
3. Blough D.S. Delayed matching in the pigeon. Journal of the Experimental Analysis of Behavior 1959, 2:151-160.
4. Canfield M.A., Honein M.A., Yuskiv N., Xing J., Mai C.T., Collins J.S., et al. National estimates and race/ethnic-specific variation of selected birth defects in the United States, 1999-2001. Birth Defects Research. Part A, Clinical and Molecular Teratology 2006, 76:747-756.
5. Chen Y., Dyakin V.V., Branch C.A., Ardekani B., Yang D., Guilfoyle D.N., et al. In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. Neurobiology of Aging 2009, 30:1453-1465.
6. Costa A.C.S., Walsh K., Davisson M.T. Motor dysfunction in a mouse model for Down syndrome. Physiology and Behavior 1999, 68:211-220.
7. Dalton A.J., Crapper D.R., Schlotterer G.R. Alzheimer's disease in Down's syndrome: visual retention deficits. Cortex 1974, 10:366-377.
8. Dalton A.J., Crapper McLachlan D.R. Incidence of memory deterioration in aging persons with Down's syndrome. Perspectives and progress in mental retardation, vol. II - biomedical aspects 1984, 55-62. University Park Press, Baltimore, MD. J.M. Berg (Ed.).
9. Dalton A.J., Crapper-McLachlan D.R. Clinical expression of Alzheimer's disease in Down's syndrome. The Psychiatric Clinics of North America 1986, 9:659-670.
10. Davisson M.T., Schmidt C., Akeson E.C. Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome. Molecular genetics of chromosome 21 and Down syndrome 1990, 263-280. Wiley-Liss, New York. D. Patterson, C.J. Epstein (Eds.).
11. Davisson M.T., Schmidt C., Reeves R.H., Irving N.G., Akeson E.C., Harris B.S., et al. Segmental trisomy as a mouse model for Down syndrome. The phenotypic mapping of Down syndrome and other aneuploid conditions. Progress in clinical and biological research 1993, vol. 384:117-133. Wiley-Liss, New York.
12. Dawson G., Meltzoff A.N. Neuropsychological correlates of early symptoms of autism. Child Development 1998, 69:1276-1285.
13. Dawson G., Osterling J., Rinaldi J., Carver L., Mcpartland J. Brief report: Recognition memory and stimulus-reward associations: indirect support for the role of ventromedial prefrontal dysfunction in autism. Journal of Autism and Developmental Disorders 2001, 31:337-341.
14. Demas G.E., Nelson R.J., Krueger B.K., Yarowsky P.J. Spatial memory deficits in segmental trisomic Ts65Dn mice. Behavioural Brain Research 1996, 82:85-92.
15. Demas G.E., Nelson R.J., Krueger B.K., Yarowsky P.J. Impaired spatial working and reference memory in segmental trisomy. Behavioural Brain Research 1998, 90:199-201.
16. Devenny D.A., Silverman W.P., Hill A.L., Jenkins E., Sersen E.A., Wisniewski K.E. Normal ageing in adults with Down's syndrome: a longitudinal study. Journal of Intellectual Disability Research 1996, 40:208-221.
17. Dowdy-Sanders N.C., Wenger G.R. Working memory in the Ts65Dn mouse, a model for Down syndrome. Behavioural Brain Research 2006, 168:349-352.
18. Escorihuela R.M., Fernández-Teruel A., Vallina I.F., Baamonde C., Lumbreras M.A., Dierssen M., et al. A behavioral assessment of Ts65Dn mice: a putative Down syndrome model. Neuroscience Letters 1995, 199:143-146.
19. Escorihuela R.M., Vallina I.F., Martínez-Cué C., Baamonde C., Dierssen M., Tobeña A., et al. Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome. Neuroscience Letters 1998, 247:171-174.
20. Granholm A-CE, Sanders L.A., Crnic L.S. Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome. Experimental Neurology 2000, 161:647-663.
21. Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.S., et al. The DNA sequence of human chromosome 21. Nature 2000, 405:311-319.
22. Holtzman D.M., Santucci D., Kilbridge J., Chua-Couzens J., Fontana D.J., Daniels S.E., et al. Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:13333-13338.
23. Hunter C.L., Bimonte H.A., Granholm A.C. Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory. Behavioural Brain Research 2003, 138:121-131.
24. Lai F., Williams R.S. A prospective study of Alzheimer disease in Down syndrome. Archives of Neurology 1989, 46:849-853.
25. Laws G. Working memory in children and adolescents with Down syndrome: evidence from a colour memory experiment. Journal of Child Psychology and Psychiatry and Allied Disciplines 2002, 43:353-364.
26. Lott I.T., Head E. Down syndrome and Alzheimer's disease: a link between development and aging. Mental Retardation and Developmental Disabilities Research Reviews 2001, 7:172-178.
27. Megias M., Verduga R., Dierssen M., Florez J., Insausti R., Crespo D. Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice. Neuroreport 1997, 8:3475-3478.
28. Moser M.B. Making more synapses: a way to store information?. Cellular and Molecular Life Sciences 1999, 55:593-600.
29. Nadel L. Down's syndrome: a genetic disorder in biobehavioral perspective. Genes, Brain and Behavior 2003, 2:156-166.
30. Numminen H., Service E., Ahonen T., Ruoppila I. Working memory and everyday cognition in adults with Down's syndrome. Journal of Intellectual Disability Research 2001, 45:157-168.
31. Pham T.M., Söderström S., Winblad B., Mohammed A.H. Effects of environmental enrichment on cognitive function and hippocampal NGF in the non-handled rats. Behavioural Brain Research 1999, 103:63-70.
32. Reeves R.H., Irving N.G., Moran T.H., Wohn A., Kitt C., Sisodia S.S., et al. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nature Genetics 1995, 11:177-184.
33. Richtsmeier J.T., Baxter L.L., Reeves R.H. Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice. Developmental Dynamics 2000, 217:137-145.
34. Sago H., Carlson E.J., Smith D.J., Rubin E.M., Crnic L.S., Huang T., et al. Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome. Pediatric Research 2000, 48:606-613.
35. Sanders N.C., Williams D.K., Wenger G.R. Does the learning deficit observed under an incremental repeated acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age?. Behavioural Brain Research 2009, 203:137-142.
36. Seo H., Isacson O. Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice. Experimental Neurology 2005, 193:469-480.
37. Slikker W., Paule M.G., Ali S.F., Scallet A.C., Bailey J.R. Behavioral, neurochemical and neurohistological effects of chronic marijuana smoke exposure in the nonhuman primate. Marijuana/cannabinoids: neurophysiology and neurobiology 1992, 219-273. CRC Press, Boca Raton. L.L. Murphy, A. Bartke (Eds.).
38. Toyoda A., Noguchi H., Taylor T.D., Ito T., Pletcher M.T., Sakaki Y., et al. Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region. Genome Research 2002, 12:1323-1332.
39. Vogel W., Kun K.J., Meshorer E. Effects of environmental enrichment and environmental deprivation on cognitive functioning in institutionalized retardates. Journal of Consulting Psychology 1967, 31:570-576.
40. Wenger G.R., Schmidt C., Davisson M.T. Operant conditioning in the Ts65Dn mouse: learning. Behavior Genetics 2004, 34:105-119.
41. Wiseman F.K., Alford K.A., Tybulewicz V.L.J., Fisher E.M.C. Down syndrome-recent progress and future prospects. Human Molecular Genetics 2009, 18:R75-R83.
42. Wisniewski K.E., Dalton A.J., Crapper McLachlan D.R., Wen G.Y., Wisniewski H.M. Alzheimer's disease in Down's syndrome: clinicopathologic studies. Neurology 1985, 35:957-961.
43. Wisniewski K.E., Wisniewski H.M., Wen G.Y. Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Annals of Neurology 1985, 17:278-282.