Efficacy and safety of topical antifungals in the treatment of dermatomycosis: A systematic review

British Journal of Dermatology

Volumn 166, Issue 5, 2012, Pages 927-933

  Rotta, I ^a   Sanchez, A ^a   Goncalves P R ^a   Otuki, M F ^a   Correr, C J ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BIFONAZOLE; BUTENAFINE; CICLOPIROXOLAMINE; CLOTRIMAZOLE; ECONAZOLE; KETOCONAZOLE; MICONAZOLE; NAFTIFINE; OXICONAZOLE; PLACEBO; SERTACONAZOLE; TERBINAFINE; TIOCONAZOLE;

APPLICATION SITE BURNING; COCHRANE LIBRARY; CONFIDENCE INTERVAL; DERMATOMYCOSIS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; HUMAN; MEDLINE; META ANALYSIS; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK; SENSITIVITY ANALYSIS; SYSTEMATIC REVIEW;

ADMINISTRATION, CUTANEOUS; ANTIFUNGAL AGENTS; DERMATOMYCOSES; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 84860340696     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2012.10815.x     Document Type: Review

References (17)

1. Borgers M, Degreef H, Cauwenbergh G,. Fungal infections of the skin: infection process and antimycotic therapy. Curr Drug Targets 2005; 6: 849-62. (Pubitemid 41672447)
2. Charles AJ,. Superficial cutaneous fungal infections in tropical countries. Dermatol Ther 2009; 22: 550-9.
3. Garber G,. An overview of fungal infections. Drugs 2001; 61 (Suppl. 1): 1-12. (Pubitemid 32151108)
4. Gupta AK, Einarson TR, Summerbell RC, Shear NH,. An overview of topical antifungal therapy in dermatomycoses. A North American perspective. Drugs 1998; 55: 645-74. (Pubitemid 28203773)
5. Gupta AK, Cooper EA,. Update in antifungal therapy of dermatophytosis. Mycopathologia 2008; 166: 353-67.
6. Meis JF, Verweij PE,. Current management of fungal infections. Drugs 2001; 1: 13-25. (Pubitemid 32151109)
7. Severo LC, Londero AT,. Tratado de Infectologia. São Paulo: Atheneu, 2002.
8. Crawford F, Hollis S,. Topical treatments for fungal infections of the skin and nails of the foot. Cochrane Database Syst Rev 2007; 3: 1-157.
9. Hainer BL,. Dermatophyte infections. Am Fam Physician 2003; 67: 101-8. (Pubitemid 36227391)
10. Hart R, Bell-Syer SE, Crawford F, et al. Systematic review of topical treatments for fungal infections of the skin and nails of the feet. BMJ 1999; 319: 79-82. (Pubitemid 29313235)
11. Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions, version 5.0.2 [updated September 2009] Available at: (last accessed 19 January 2012).
12. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17: 1-12. (Pubitemid 26120810)
13. Ablon G, Rosen T, Spedale J,. Comparative efficacy of naftifine, oxiconazole, and terbinafine in short-term treatment of tinea pedis. Int J Dermatol 1996; 35: 591-3. (Pubitemid 26261936)
14. Crawford F, Harris R, Williams HC,. Are placebo-controlled trials of creams for athlete's foot still justified? Br J Dermatol 2008; 159: 773-9.
15. Williams H,. Fungal infections of skin and nails of feet. Pragmatic clinical trial is now needed. BMJ 1999; 319: 1070-1. (Pubitemid 29476447)
16. Lu G, Ades AE,. Combination of direct and indirect evidence in mixed treatment comparisons. Stat Med 2004; 23: 3105-24. (Pubitemid 39334902)
17. Lumley T,. Network meta-analysis for indirect treatment comparisons. Stat Med 2002; 21: 2313-24.